Dual topology of functional Toll-like receptor 3 expression in human hepatocellular carcinoma: Differential signaling mechanisms of TLR3-induced NF-κB activation and apoptosis

International Journal of Oncology

Volumn 33, Issue 5, 2008, Pages 929-936

  Yoneda, Kentaro ^a   Sugimoto, Kazushi ^a   Shiraki, Katsuya ^a   Tanaka, Junichiro ^a   Beppu, Tetsuya ^a   Fuke, Hiroyuki ^a   Yamamoto, Norihiko ^a   Masuya, Masahiro ^b   Horie, Ryo ^c   Uchida, Kazuhiko ^c   Takei, Yoshiyuki ^a  

^a MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b MIE UNIVERSITY HOSPITAL   (Japan)

^c UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Apoptosis; Hepatocellular carcinoma; Nuclear factor B; Toll like receptor 3

Indexed keywords

BETA INTERFERON; CASPASE 3; DOUBLE STRANDED RNA; FLICE INHIBITORY PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; MESSENGER RNA; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN BCL XL; SURVIVIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; X LINKED INHIBITOR OF APOPTOSIS; TLR3 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CELL MEMBRANE; CELL SURFACE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; DOWN REGULATION; FLOW CYTOMETRY; GENE ACTIVATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; PATTERN RECOGNITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; GENETICS; LIVER TUMOR; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL MEMBRANE; CELL SURVIVAL; CYTOPLASM; HUMANS; INTERFERON-BETA; LIVER NEOPLASMS; NF-KAPPA B; POLY I-C; RNA, MESSENGER; SIGNAL TRANSDUCTION; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TOLL-LIKE RECEPTOR 3; TRANSFECTION;

EID: 58149195681     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000080     Document Type: Article

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