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Volumn 1, Issue 7, 2006, Pages 753-764

HTRF®: Pioneering technology for high-throughput screening

Author keywords

assay; fluorescence; FRET; GPCR screening; HTS; kinase screening; TR FRET

Indexed keywords


EID: 58049211410     PISSN: 17460441     EISSN: 1746045X     Source Type: Journal    
DOI: 10.1517/17460441.1.7.753     Document Type: Article
Times cited : (30)

References (51)
  • 2
    • 84985559865 scopus 로고
    • Energy transfer luminescence of europium (III) and terbium (III) cryptates of macrobicyclic polypyridine ligands
    • ALPHA B, LEHN JM, MATHIS G: Energy transfer luminescence of europium (III) and terbium (III) cryptates of macrobicyclic polypyridine ligands. Chem Int Ed Engl. (1987) 26:266-713.
    • (1987) Chem Int Ed Engl. , vol.26 , pp. 266-713
    • Alpha, B.1    Lehn, J.M.2    Mathis, G.3
  • 4
    • 33846238764 scopus 로고    scopus 로고
    • Fluorescence technologies for the investigation of chemical libraries
    • Aug
    • TRINQUET E, MATHIS G: Fluorescence technologies for the investigation of chemical libraries. Mol Biosyst. 2006 Aug; 2(8):380-387.
    • (2006) Mol Biosyst. , vol.2 , Issue.8 , pp. 380-387
    • Trinquet, E.1    Mathis, G.2
  • 5
    • 0035860103 scopus 로고    scopus 로고
    • Homogeneous time resolved fluorescence resonance energy transfer using rare earth cryptates as a tool for probing molecular interactions in biology
    • BAZIN H, PRÉAUDAT M, TRINQUET E, MATHIS G: Homogeneous time resolved fluorescence resonance energy transfer using rare earth cryptates as a tool for probing molecular interactions in biology. Spectrochim. Acta. A. Mol. Biomol. Spectrosc. (2001) 57:2197-2211.
    • (2001) Spectrochim. Acta. A. Mol. Biomol. Spectrosc. , vol.57 , pp. 2197-2211
    • Bazin, H.1    Préaudat, M.2    Trinquet, E.3    Mathis, G.4
  • 6
    • 0036182267 scopus 로고    scopus 로고
    • Time-resolved amplification of cryptate emission: A versatile technology to trace biomolecular interactions
    • BAZIN H, TRINQUET E, MATHIS G: Time-resolved amplification of cryptate emission: a versatile technology to trace biomolecular interactions. J. Biotechnol.(2002) 82:233-250.
    • (2002) J. Biotechnol. , vol.82 , pp. 233-250
    • Bazin, H.1    Trinquet, E.2    Mathis, G.3
  • 7
    • 0003162214 scopus 로고    scopus 로고
    • A homogeneous, time-resolved fluorescence method for drug discovery
    • Devlin JP, (Ed.) Marcel Dekker, Inc., New York
    • KOLB A, BURKE J, MATHIS G: A homogeneous, time-resolved fluorescence method for drug discovery. in: high throughput screening, the discovery of bioactive substances. Devlin JP, (Ed.) Marcel Dekker, Inc., New York (1997) (345)360.
    • (1997) High Throughput Screening, the Discovery of Bioactive Substances , Issue.345 , pp. 360
    • Kolb, A.1    Burke, J.2    Mathis, G.3
  • 8
    • 0000276429 scopus 로고    scopus 로고
    • MANLYS: Use of a novel homogenous fluorescent technology in high throughput screening
    • KOLB J, YAMANAKE G, MANLYS: Use of a novel homogenous fluorescent technology in high throughput screening. J. Biomol. Screening (1996) 1:203-210.
    • (1996) J. Biomol. Screening , vol.1 , pp. 203-210
    • Kolb, J.1    Yamanake, G.2
  • 9
    • 0033368046 scopus 로고    scopus 로고
    • Homogeneous time resolved fluorescence, point-counterpoint
    • MATHIS G: Homogeneous time resolved fluorescence, point-counterpoint. J. Biomol Screening. (1999) 4:309-313.
    • (1999) J. Biomol Screening. , vol.4 , pp. 309-313
    • Mathis, G.1
  • 11
    • 80052413825 scopus 로고    scopus 로고
    • Introduction of a new HTRF® acceptor, d2. Development of a complete GPCR platform for a Gs, Gi and Gq screening
    • Geneva, CH
    • AMORAVAIN M, LYOTARD S, JAGA D, et al. : Introduction of a new HTRF® acceptor, d2. Development of a complete GPCR platform for a Gs, Gi and Gq screening. SBS 11th Annual Conference. Geneva, CH. (2005).
    • (2005) SBS 11th Annual Conference
    • Amoravain, M.1    Lyotard, S.2    Jaga, D.3
  • 13
    • 33744546849 scopus 로고    scopus 로고
    • HTRF KinEASE: A new solution for screening serine-threonine kinases
    • DREXLER C: HTRF KinEASE: a new solution for screening serine-threonine kinases. Nat. Methods (2006) 3:i-ii.
    • (2006) Nat. Methods , vol.3
    • Drexler, C.1
  • 16
    • 0347512128 scopus 로고    scopus 로고
    • Homogeneous time resolved fluorescence assay to measure histamine release
    • CLARET E, OULED-DIAF J, SEGUIN P: Homogeneous time resolved fluorescence assay to measure histamine release. Comb. Chem. High Throughput Screen. (2003) 6:789-794.
    • (2003) Comb. Chem. High Throughput Screen. , vol.6 , pp. 789-794
    • Claret, E.1    Ouled-Diaf, J.2    Seguin, P.3
  • 17
    • 0034668139 scopus 로고    scopus 로고
    • Quantitation of amyloid-β peptides in biological milieu using a novel homogeneous time-resolved fluorescence (HTRF®) assay
    • CLARKE EE, SHEARMAN S: Quantitation of amyloid-β peptides in biological milieu using a novel homogeneous time-resolved fluorescence (HTRF®) assay. J. Neurosci. Meth. (2000) 102:61-68.
    • (2000) J. Neurosci. Meth. , vol.102 , pp. 61-68
    • Clarke, E.E.1    Shearman, S.2
  • 18
    • 0033812471 scopus 로고    scopus 로고
    • High throughput screening for human interferon-gamma production using Homogeneous Time-Resolved Fluorescence
    • ENOMOTO K, AONO Y, MITSUGI T, SUZUKI R, PRÉAUDAT M, MATHIS G: High throughput screening for human interferon-gamma production using Homogeneous Time-Resolved Fluorescence. J. Biomol. Screen. (2000) 5:263-268.
    • (2000) J. Biomol. Screen. , vol.5 , pp. 263-268
    • Enomoto, K.1    Aono, Y.2    Mitsugi, T.3    Suzuki, R.4    Préaudat, M.5    Mathis, G.6
  • 19
    • 0038729338 scopus 로고    scopus 로고
    • Measuring human β-secretase (BACE1) activity using homogeneous time-resolved fluorescence
    • KENNEDY ME,WANG W: Measuring human β-secretase (BACE1) activity using homogeneous time-resolved fluorescence. Anal. Biochem. (2003) 319:49-55.
    • (2003) Anal. Biochem. , vol.319 , pp. 49-55
    • Kennedy Mewang, W.1
  • 20
    • 0029134581 scopus 로고
    • Probing molecular interactions with homogeneous techniques based on rare earth cryptates and fluorescence energy transfer
    • MATHIS G: Probing molecular interactions with homogeneous techniques based on rare earth cryptates and fluorescence energy transfer. Clin Chem. (1995) 41:1391-1397.
    • (1995) Clin Chem. , vol.41 , pp. 1391-1397
    • Mathis, G.1
  • 21
    • 0030952352 scopus 로고    scopus 로고
    • Homogeneous immunoassay and other applications of a novel fluorescence energy transfer technology using rare earth cryptates
    • MATHIS G: Homogeneous immunoassay and other applications of a novel fluorescence energy transfer technology using rare earth cryptates. J. Clin. Ligand Assay. (1997) 20:141-147.
    • (1997) J. Clin. Ligand Assay. , vol.20 , pp. 141-147
    • Mathis, G.1
  • 22
    • 0027227462 scopus 로고
    • Rare earth cryptates and homogeneous fluoroimmunoassays with human sera
    • MATHIS G: Rare earth cryptates and homogeneous fluoroimmunoassays with human sera. Clin Chem. (1993) 39:1953-1959.
    • (1993) Clin Chem. , vol.39 , pp. 1953-1959
    • Mathis, G.1
  • 23
    • 0030865745 scopus 로고    scopus 로고
    • Homogeneous immunoassays using rare earth cryptates and time resolved fluorescence. Principles and specific advantages for tumor markers
    • MATHIS G, SOCQUET F, VIGUIER M, DARBOURET B: Homogeneous immunoassays using rare earth cryptates and time resolved fluorescence. Principles and specific advantages for tumor markers. Anticancer Res. (1997) 17:3011-3014.
    • (1997) Anticancer Res. , vol.17 , pp. 3011-3014
    • Mathis, G.1    Socquet, F.2    Viguier, M.3    Darbouret, B.4
  • 24
    • 18844418158 scopus 로고    scopus 로고
    • Development of a CD28/CD86 (B7-2) binding assay for high throughput screening by homogenous time-resolved fluorescence
    • MELLOR GW, BURDEN MN: Development of a CD28/CD86 (B7-2) binding assay for high throughput screening by homogenous time-resolved fluorescence. J. Biomol. Screen. (1998) 3:91-99.
    • (1998) J. Biomol. Screen. , vol.3 , pp. 91-99
    • Mellor, G.W.1    Burden, M.N.2
  • 25
    • 0035884591 scopus 로고    scopus 로고
    • Allophycocyanin 1 as a near-infrared fluorescent tracer: Isolation, characterization, chemical modification, and use in homogeneous fluorescence resonance energy transfer
    • TRINQUET E, MAURIN F, PRÉAUDAT M, MATHIS G: Allophycocyanin 1 as a near-infrared fluorescent tracer: isolation, characterization, chemical modification, and use in homogeneous fluorescence resonance energy transfer. Anal. Biochem. (2001) 296:232-244.
    • (2001) Anal. Biochem. , vol.296 , pp. 232-244
    • Trinquet, E.1    Maurin, F.2    Préaudat, M.3    Mathis, G.4
  • 26
    • 0032964339 scopus 로고    scopus 로고
    • Mono(di)nuclear Europium(lll) complexes of macrobi(tri)cyclic cryptands derived from diazatetralactams as luminophores in aqueous solution
    • GALAUP C, PICARD C, CATHALA B et al.: Mono(di)nuclear Europium(lll) complexes of macrobi(tri)cyclic cryptands derived from diazatetralactams as luminophores in aqueous solution. Helv. Chim. Acta. (1999) 82:543-560.
    • (1999) Helv. Chim. Acta. , vol.82 , pp. 543-560
    • Galaup, C.1    Picard, C.2    Cathala, B.3
  • 27
    • 80052412506 scopus 로고    scopus 로고
    • Evaluation of IP-One, a new HTRF assay to monitor Gq coupled GPCR response. Comparison in HTS conditions with FLIPR
    • Geneva, CH
    • TOZAWA-TAKAHASHI F, TANAKA Y et al.: Evaluation of IP-One, a new HTRF assay to monitor Gq coupled GPCR response. Comparison in HTS conditions with FLIPR. 11th SBS Annual Conference. Geneva, CH. (2005).
    • (2005) 11th SBS Annual Conference
    • Tozawa-Takahashi, F.1    Tanaka, Y.2
  • 28
    • 0035880150 scopus 로고    scopus 로고
    • A homogeneous europium cryptate-based assay for the diagnosis of mutations by time-resolved fluorescence resonance energy transfer
    • LOPEZ-CRAPEZ E, BAZIN H, ANDRE E, NOLETTI J, GRENIER J, MATHIS G. A homogeneous europium cryptate-based assay for the diagnosis of mutations by time-resolved fluorescence resonance energy transfer. Nucleic Acids Res. (2001) 29:14e70.
    • (2001) Nucleic Acids Res. , vol.29 , Issue.14
    • Lopez-Crapez, E.1    Bazin, H.2    Andre, E.3    Noletti, J.4    Grenier, J.5    Mathis, G.6
  • 30
    • 0031821433 scopus 로고    scopus 로고
    • Tyrosine kinase assays adapted to homogenous time-resolved fluorescence
    • KOLB AJ, KAPLITA PV, HAYES DJ et al.: Tyrosine kinase assays adapted to homogenous time-resolved fluorescence. Discovery Drug Technol. (1998) 3:333-342.
    • (1998) Discovery Drug Technol. , vol.3 , pp. 333-342
    • Kolb, A.J.1    Kaplita, P.V.2    Hayes, D.J.3
  • 31
    • 0037108991 scopus 로고    scopus 로고
    • Homogeneous time-resolved fluorescence assay for identifying p53 interactions with its protein partners, directly in a cellular extract
    • LEBLANC V, DELAUNAY V, LELONG JC, GAS F, MATHIS G, GRASSI J, MAY E: Homogeneous time-resolved fluorescence assay for identifying p53 interactions with its protein partners, directly in a cellular extract. Anal. Biochem. (2002) 308:247-254.
    • (2002) Anal. Biochem. , vol.308 , pp. 247-254
    • Leblanc, V.1    Delaunay, V.2    Lelong, J.C.3    Gas, F.4    Mathis, G.5    Grassi, J.6    May, E.7
  • 32
    • 0035991289 scopus 로고    scopus 로고
    • A homogeneous caspase 3 activity assay using HTRF® technology
    • PRÉAUDAT M, OULED-DIAF J, ALPHA-BAZIN B et al.: A homogeneous caspase 3 activity assay using HTRF® technology. J. Biomol. Screening. (2002) 7:267-274.
    • (2002) J. Biomol. Screening. , vol.7 , pp. 267-274
    • Préaudat, M.1    Ouled-Diaf, J.2    Alpha-Bazin, B.3
  • 33
    • 0032749109 scopus 로고    scopus 로고
    • Application of homogeneous time-resolved fluorescence (HTRF®) to monitor poly-ubiquitination of wild-type p53
    • YABUKI N, WATANABE S, KUDOH T, NIHIRA S, MIYAMOTO C: Application of homogeneous time-resolved fluorescence (HTRF®) to monitor poly-ubiquitination of wild-type p53. Comb. Chem. High Throughput Screen. (1999) 2:27-87.
    • (1999) Comb. Chem. High Throughput Screen. , vol.2 , pp. 27-87
    • Yabuki, N.1    Watanabe, S.2    Kudoh, T.3    Nihira, S.4    Miyamoto, C.5
  • 34
    • 0034802615 scopus 로고    scopus 로고
    • Use of homogeneous time-resolved fluorescence energy transfer in the measurement of nuclear receptor activation
    • ZHOU G, CUMMINGS R, HERMES J, MOLLER DE: Use of homogeneous time-resolved fluorescence energy transfer in the measurement of nuclear receptor activation. Methods. (2001) 25:54-61.
    • (2001) Methods , vol.25 , pp. 54-61
    • Zhou, G.1    Cummings, R.2    Hermes, J.3    Moller, D.E.4
  • 38
    • 80052403602 scopus 로고    scopus 로고
    • Validation of the HTRF® technology for high throughput quantification of cAMP production mediated by activation of GPCR - Comparison with flashplate
    • Baltimore, USA
    • HAMON J, MARTIN B, MEUNIER E, CASAMITJANA O, OUAGUED M, ROMAN F: Validation of the HTRF® technology for high throughput quantification of cAMP production mediated by activation of GPCR - comparison with flashplate. SBS 7th Annual Conference. Baltimore, USA (2001).
    • (2001) SBS 7th Annual Conference
    • Hamon, J.1    Martin, B.2    Meunier, E.3    Casamitjana, O.4    Ouagued, M.5    Roman, F.6
  • 39
    • 33749439331 scopus 로고    scopus 로고
    • D-myo-Inositol 1-phosphate as a surrogate of D-myo-inositol 1,4,5-tris phosphate to monitor G protein-coupled receptor activation
    • TRINQUET E, FINK M, BAZIN H et al.: D-myo-Inositol 1-phosphate as a surrogate of D-myo-inositol 1,4,5-tris phosphate to monitor G protein-coupled receptor activation Anal. Biochem. (2006) 358:126-135.
    • (2006) Anal. Biochem. , vol.358 , pp. 126-135
    • Trinquet, E.1    Fink, M.2    Bazin, H.3
  • 40
    • 80052398804 scopus 로고    scopus 로고
    • Screening and profiling for kinases: Development of a unique and versatile platform
    • Basel, CH. May
    • CHAMBON M, OTTO-BRUC A, HAMON H V, PERNELLE C: Screening and profiling for kinases: development of a unique and versatile platform. Miptec. Basel, CH. May (2005).
    • (2005) Miptec
    • Chambon, M.1    Otto-Bruc, A.2    Hamon, H.V.3    Pernelle, C.4
  • 41
    • 0033541662 scopus 로고    scopus 로고
    • Homogeneous proximity tyrosine kinase assays: Scintillation proximity assay versus homogeneous time-resolved fluorescence
    • PARK YW, CUMMINGS RT, WU L et al.: Homogeneous proximity tyrosine kinase assays: scintillation proximity assay versus homogeneous time-resolved fluorescence. Anal Biochem. (1999) 269:94-104.
    • (1999) Anal Biochem. , vol.269 , pp. 94-104
    • Park, Y.W.1    Cummings, R.T.2    U, L.W.3
  • 42
    • 23944499553 scopus 로고    scopus 로고
    • Purification and kinetic characterization of recombinant human mitogen-activated protein kinase kinase kinase COT and the complexes with its cellular partner NF-kB1 p105
    • JIA Y, QUINN C, BUMP I et al.: Purification and kinetic characterization of recombinant human mitogen-activated protein kinase kinase kinase COT and the complexes with its cellular partner NF-kB1 p105. Arch. Biochem. Biophys. (2005) 441:64-74.
    • (2005) Arch. Biochem. Biophys. , vol.441 , pp. 64-74
    • Jia, Y.1    Quinn, C.2    Bump, I.3
  • 43
    • 33644687467 scopus 로고    scopus 로고
    • Comparative analysis of various in vitro COT kinase assay formats and their applications in inhibitor identification and characterization
    • JIA Y, QUINN C, CLABBERS A, TALANIAN R, XU Y, WISHART N et al.: Comparative analysis of various in vitro COT kinase assay formats and their applications in inhibitor identification and characterization. Anal. Biochem. (2006) 350:268-276.
    • (2006) Anal. Biochem. , vol.350 , pp. 268-276
    • Jia, Y.1    Quinn, C.2    Clabbers, A.3    Talanian, R.4    U, Y.X.5    Wishart, N.6
  • 44
    • 13844292596 scopus 로고    scopus 로고
    • Suppression of CD4+ T cell activation by a novel inhibitor of Src family kinases
    • MCRAE B, WALLACE C, FITZGERALD DIXON K et al.: Suppression of CD4+ T cell activation by a novel inhibitor of Src family kinases. Internat. Immunopharm. (2005) 5:667-677.
    • (2005) Internat. Immunopharm. , vol.5 , pp. 667-677
    • McRae, B.1    Wallace, C.2    Fitzgerald Dixon, K.3
  • 45
    • 33747880633 scopus 로고    scopus 로고
    • Homogeneous time-resolved fluorescence and its applications for kinase assays in drug discovery
    • In Press
    • YONG JIA, QUINN CM, GAGNON AI, TALANIAN R: Homogeneous time-resolved fluorescence and its applications for kinase assays in drug discovery. Anal. Biochem. (2006) (In Press).
    • (2006) Anal. Biochem.
    • Jia, Y.1    Quinn, C.M.2    Gagnon, A.I.3    Talanian, R.4
  • 46
    • 80052414874 scopus 로고    scopus 로고
    • Use of Europium cryptate labeled phospho-specific antibodies for high throughput kinase assays
    • Basel, CH
    • OULED-DIAF J, RUSSELLO SV, ROURKE K, DEGORCE F, BUNKER C, CLARET EJ: Use of Europium cryptate labeled phospho-specific antibodies for high throughput kinase assays. Miptec. Basel, CH. (2003).
    • (2003) Miptec
    • Ouled-Diaf, J.1    Russello, S.V.2    Rourke, K.3    Degorce, F.4    Bunker, C.5    Claret, E.J.6
  • 47
    • 80052422781 scopus 로고    scopus 로고
    • MABEL M, MATHIS G: US5527684 (2006)
    • MABEL M, MATHIS G: US5527684 (2006).
  • 48
    • 80052414355 scopus 로고    scopus 로고
    • http://www.htrf.com. Cisbio (2006).
    • (2006) Cisbio
  • 49
    • 80052417137 scopus 로고    scopus 로고
    • Cisbio international
    • http://www.htrf.com/resources/details/?tid=7 &rid=21 Cisbio international. HTRF resource library (2006).
    • (2006)
  • 50
    • 80052413258 scopus 로고    scopus 로고
    • http:/www./cerep.fr/cerep/users/pages/productsservices/popupkinase.asp Cerep. Description of HTRF kinase assay format (2004).
    • (2004)


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