-
1
-
-
10944222754
-
Role of programmed cell death in normal neuronal development and function
-
Buss RR, Oppenheim RW. Role of programmed cell death in normal neuronal development and function. Anat Sci Int 2004; 79:191-7.
-
(2004)
Anat Sci Int
, vol.79
, pp. 191-197
-
-
Buss, R.R.1
Oppenheim, R.W.2
-
2
-
-
0031057656
-
Bcl-2 gene family in the nervous system
-
Merry DE, Korsmeyer SJ. Bcl-2 gene family in the nervous system. Annu Rev Neurosci 1997; 20:245-67.
-
(1997)
Annu Rev Neurosci
, vol.20
, pp. 245-267
-
-
Merry, D.E.1
Korsmeyer, S.J.2
-
4
-
-
0041488911
-
Trk receptors: Roles in neuronal signal transduction
-
Huang EJ, Reichardt LF. Trk receptors: roles in neuronal signal transduction. Annu Rev Biochem 2003; 72:609-42.
-
(2003)
Annu Rev Biochem
, vol.72
, pp. 609-642
-
-
Huang, E.J.1
Reichardt, L.F.2
-
5
-
-
1542381057
-
Cell cycle regulation of neuronal apoptosis in development and disease
-
Becker EB, Bonni A. Cell cycle regulation of neuronal apoptosis in development and disease. Prog Neurobiol 2004; 72:1-25.
-
(2004)
Prog Neurobiol
, vol.72
, pp. 1-25
-
-
Becker, E.B.1
Bonni, A.2
-
6
-
-
33947109561
-
Cell cycle molecules define a pathway required for neuron death in development and disease
-
Greene LA, Liu DX, Troy CM, Biswas SC. Cell cycle molecules define a pathway required for neuron death in development and disease. Biochim Biophys Acta 2007; 1772:392-401.
-
(2007)
Biochim Biophys Acta
, vol.1772
, pp. 392-401
-
-
Greene, L.A.1
Liu, D.X.2
Troy, C.M.3
Biswas, S.C.4
-
7
-
-
34247508686
-
Cell cycle regulation in the postmitotic neuron: Oxymoron or new biology?
-
Herrup K, Yang Y. Cell cycle regulation in the postmitotic neuron: oxymoron or new biology? Nat Rev Neurosci 2007; 8:368-78.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 368-378
-
-
Herrup, K.1
Yang, Y.2
-
8
-
-
33645960654
-
Stabilizers and destabilizers controlling cell cycle oscillators
-
Guardavaccaro D, Pagano M. Stabilizers and destabilizers controlling cell cycle oscillators. Mol Cell 2006; 22:1-4.
-
(2006)
Mol Cell
, vol.22
, pp. 1-4
-
-
Guardavaccaro, D.1
Pagano, M.2
-
9
-
-
0035990906
-
Cyclin-dependent kinases as potential targets to improve stroke outcome
-
O'Hare M, Wang F, Park DS. Cyclin-dependent kinases as potential targets to improve stroke outcome. Pharmacol Ther 2002; 93:135-43.
-
(2002)
Pharmacol Ther
, vol.93
, pp. 135-143
-
-
O'Hare, M.1
Wang, F.2
Park, D.S.3
-
10
-
-
34547952048
-
Cdk1 is sufficient to drive the mammalian cell cycle
-
Santamaria D, Barriere C, Cerqueira A, Hunt S, Tardy C, Newton K, Caceres JF, Dubus P, Malumbres M, Barbacid M. Cdk1 is sufficient to drive the mammalian cell cycle. Nature 2007; 448:811-5.
-
(2007)
Nature
, vol.448
, pp. 811-815
-
-
Santamaria, D.1
Barriere, C.2
Cerqueira, A.3
Hunt, S.4
Tardy, C.5
Newton, K.6
Caceres, J.F.7
Dubus, P.8
Malumbres, M.9
Barbacid, M.10
-
11
-
-
0036282745
-
Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery
-
Konishi Y, Lehtinen M, Donovan N, Bonni A. Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery. Mol Cell 2002; 9:1005-16.
-
(2002)
Mol Cell
, vol.9
, pp. 1005-1016
-
-
Konishi, Y.1
Lehtinen, M.2
Donovan, N.3
Bonni, A.4
-
12
-
-
0037335443
-
The E2F-Cdc2 cell cycle pathway specifically mediates activity deprivation-induced apoptosis of postmitotic neurons
-
Konishi Y, Bonni A. The E2F-Cdc2 cell cycle pathway specifically mediates activity deprivation-induced apoptosis of postmitotic neurons. J Neurosci 2003; 23:1649-58.
-
(2003)
J Neurosci
, vol.23
, pp. 1649-1658
-
-
Konishi, Y.1
Bonni, A.2
-
13
-
-
0031006939
-
Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain
-
Vincent I, Jicha G, Rosado M, Dickson DW. Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain. J Neurosci 1997; 17:3588-98.
-
(1997)
J Neurosci
, vol.17
, pp. 3588-3598
-
-
Vincent, I.1
Jicha, G.2
Rosado, M.3
Dickson, D.W.4
-
14
-
-
0032522911
-
Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain
-
Busser J, Geldmacher DS, Herrup K. Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain. J Neurosci 1998; 18:2801-7.
-
(1998)
J Neurosci
, vol.18
, pp. 2801-2807
-
-
Busser, J.1
Geldmacher, D.S.2
Herrup, K.3
-
15
-
-
0033635551
-
Mitotic activation: A convergent mechanism for a cohort of neurodegenerative diseases
-
Husseman JW, Nochlin D, Vincent I. Mitotic activation: a convergent mechanism for a cohort of neurodegenerative diseases. Neurobiol Aging 2000; 21:815-28.
-
(2000)
Neurobiol Aging
, vol.21
, pp. 815-828
-
-
Husseman, J.W.1
Nochlin, D.2
Vincent, I.3
-
16
-
-
31944434543
-
TOR-mediated cell cycle activation causes neurodegeneration in a Drosophila tauopathy model
-
Khurana V, Lu Y, Steinhilb ML, Oldham S, Shulman JM, Feany MB. TOR-mediated cell cycle activation causes neurodegeneration in a Drosophila tauopathy model. Curr Biol 2006; 16:230-41.
-
(2006)
Curr Biol
, vol.16
, pp. 230-241
-
-
Khurana, V.1
Lu, Y.2
Steinhilb, M.L.3
Oldham, S.4
Shulman, J.M.5
Feany, M.B.6
-
18
-
-
0038003956
-
Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty
-
Burgering BM, Medema RH. Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty. J Leukoc Biol 2003; 73:689-701.
-
(2003)
J Leukoc Biol
, vol.73
, pp. 689-701
-
-
Burgering, B.M.1
Medema, R.H.2
-
19
-
-
0035019007
-
Identification and characterization of members of the FKHR (FOXO) subclass of winged-helix transcription factors in the mouse
-
Biggs WH, 3rd, Cavenee WK, Arden KC. Identification and characterization of members of the FKHR (FOXO) subclass of winged-helix transcription factors in the mouse. Mamm Genome 2001; 12:416-25.
-
(2001)
Mamm Genome
, vol.12
, pp. 416-425
-
-
Biggs 3rd, W.H.1
Cavenee, W.K.2
Arden, K.C.3
-
20
-
-
0034661826
-
Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues
-
Furuyama T, Nakazawa T, Nakano I, Mori N. Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues. Biochem J 2000; 349:629-34.
-
(2000)
Biochem J
, vol.349
, pp. 629-634
-
-
Furuyama, T.1
Nakazawa, T.2
Nakano, I.3
Mori, N.4
-
21
-
-
30444442827
-
Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain
-
Hoekman MF, Jacobs FM, Smidt MP, Burbach JP. Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain. Gene Expr Patterns 2006; 6:134-40.
-
(2006)
Gene Expr Patterns
, vol.6
, pp. 134-140
-
-
Hoekman, M.F.1
Jacobs, F.M.2
Smidt, M.P.3
Burbach, J.P.4
-
22
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 1999; 96:857-68.
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
Anderson, M.J.7
Arden, K.C.8
Blenis, J.9
Greenberg, M.E.10
-
23
-
-
33646934067
-
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span
-
Lehtinen MK, Yuan Z, Boag PR, Yang Y, Villen J, Becker EB, DiBacco S, de la Iglesia N, Gygi S, Blackwell TK, Bonni A. A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell 2006; 125:987-1001.
-
(2006)
Cell
, vol.125
, pp. 987-1001
-
-
Lehtinen, M.K.1
Yuan, Z.2
Boag, P.R.3
Yang, Y.4
Villen, J.5
Becker, E.B.6
DiBacco, S.7
de la Iglesia, N.8
Gygi, S.9
Blackwell, T.K.10
Bonni, A.11
-
24
-
-
33846295218
-
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
-
Paik JH, Kollipara R, Chu G, Ji H, Xiao Y, Ding Z, Miao L, Tothova Z, Horner JW, Carrasco DR, Jiang S, Gilliland DG, Chin L, Wong WH, Castrillon DH, DePinho RA. FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell 2007; 128:309-23.
-
(2007)
Cell
, vol.128
, pp. 309-323
-
-
Paik, J.H.1
Kollipara, R.2
Chu, G.3
Ji, H.4
Xiao, Y.5
Ding, Z.6
Miao, L.7
Tothova, Z.8
Horner, J.W.9
Carrasco, D.R.10
Jiang, S.11
Gilliland, D.G.12
Chin, L.13
Wong, W.H.14
Castrillon, D.H.15
DePinho, R.A.16
-
25
-
-
0037134040
-
-
Tran H, Brunet A, Grenier JM, Datta SR, Fornace AJ Jr, DiStefano PS, Chiang LW, Greenberg ME. DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science 2002; 296:530-4.
-
Tran H, Brunet A, Grenier JM, Datta SR, Fornace AJ Jr, DiStefano PS, Chiang LW, Greenberg ME. DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science 2002; 296:530-4.
-
-
-
-
26
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 1993; 366:461-4.
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
27
-
-
41149160386
-
Activation of FOXO1 by Cdk1 in cycling cells and postmitotic neurons
-
Yuan Z, Becker EB, Merlo P, Yamada T, DiBacco S, Konishi Y, Schaefer EM, Bonni A. Activation of FOXO1 by Cdk1 in cycling cells and postmitotic neurons. Science 2008; 319:1665-8.
-
(2008)
Science
, vol.319
, pp. 1665-1668
-
-
Yuan, Z.1
Becker, E.B.2
Merlo, P.3
Yamada, T.4
DiBacco, S.5
Konishi, Y.6
Schaefer, E.M.7
Bonni, A.8
-
28
-
-
0033546439
-
Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B
-
Rena G, Guo S, Cichy SC, Unterman TG, Cohen P. Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B. J Biol Chem 1999; 274:17179-83.
-
(1999)
J Biol Chem
, vol.274
, pp. 17179-17183
-
-
Rena, G.1
Guo, S.2
Cichy, S.C.3
Unterman, T.G.4
Cohen, P.5
-
29
-
-
0035868368
-
Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting
-
Rena G, Prescott AR, Guo S, Cohen P, Unterman TG. Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting. Biochem J 2001; 354:605-12.
-
(2001)
Biochem J
, vol.354
, pp. 605-612
-
-
Rena, G.1
Prescott, A.R.2
Guo, S.3
Cohen, P.4
Unterman, T.G.5
-
30
-
-
0036282745
-
Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery
-
Konishi Y, Lehtinen M, Donovan N, Bonni A. Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery. Molecular Cell 2002; 9:1005-16.
-
(2002)
Molecular Cell
, vol.9
, pp. 1005-1016
-
-
Konishi, Y.1
Lehtinen, M.2
Donovan, N.3
Bonni, A.4
-
31
-
-
43049151493
-
Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1
-
Petronczki M, Lenart P, Peters JM. Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1. Dev Cell 2008; 14:646-59.
-
(2008)
Dev Cell
, vol.14
, pp. 646-659
-
-
Petronczki, M.1
Lenart, P.2
Peters, J.M.3
-
32
-
-
33750032892
-
CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage
-
Huang H, Regan KM, Lou Z, Chen J, Tindall DJ. CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage. Science 2006; 314:294-7.
-
(2006)
Science
, vol.314
, pp. 294-297
-
-
Huang, H.1
Regan, K.M.2
Lou, Z.3
Chen, J.4
Tindall, D.J.5
-
33
-
-
0026452774
-
Neuronal cdc2-like kinase: A cdc2-related protein kinase with predominantly neuronal expression
-
Hellmich MR, Pant HC, Wada E, Battey JF. Neuronal cdc2-like kinase: a cdc2-related protein kinase with predominantly neuronal expression. Proc Natl Acad Sci USA 1992; 89:10867-71.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10867-10871
-
-
Hellmich, M.R.1
Pant, H.C.2
Wada, E.3
Battey, J.F.4
-
34
-
-
4544227785
-
Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice
-
Furuyama T, Kitayama K, Shimoda Y, Ogawa M, Sone K, Yoshida-Araki K, Hisatsune H, Nishikawa S, Nakayama K, Ikeda K, Motoyama N, Mori N. Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice. J Biol Chem 2004; 279:34741-9.
-
(2004)
J Biol Chem
, vol.279
, pp. 34741-34749
-
-
Furuyama, T.1
Kitayama, K.2
Shimoda, Y.3
Ogawa, M.4
Sone, K.5
Yoshida-Araki, K.6
Hisatsune, H.7
Nishikawa, S.8
Nakayama, K.9
Ikeda, K.10
Motoyama, N.11
Mori, N.12
-
36
-
-
0037237279
-
The forkhead transcription factor Foxo1 regulates adipocyte differentiation
-
Nakae J, Kitamura T, Kitamura Y, Biggs WH, 3rd, Arden KC, Accili D. The forkhead transcription factor Foxo1 regulates adipocyte differentiation. Dev Cell 2003; 4:119-29.
-
(2003)
Dev Cell
, vol.4
, pp. 119-129
-
-
Nakae, J.1
Kitamura, T.2
Kitamura, Y.3
Biggs 3rd, W.H.4
Arden, K.C.5
Accili, D.6
|