MRNA expression and transport characterization of conditionally immortalized rat brain capillary endothelial cell lines; a new in vitro BBB model for drug targeting

Journal of Drug Targeting

Volumn 8, Issue 6, 2000, Pages 357-370

  Hosoya, K I ^a   Takashima, T ^a   Tetsuka, K ^a   Nagura, T ^a   Ohtsuki, S ^a   Takanaga, H ^a   Ueda, M ^a   Yanai, N ^a   Obinata, M ^a   Terasaki, T ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Blood brain barrier; GLUT 1; P glycoprotein; Temperature sensitive SV 40T antigen; Tight junction strand protein

Indexed keywords

3 METHYLGLUCOSE; CELL ADHESION MOLECULE; CELL MARKER; CELL PROTEIN; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE; GLYCOPROTEIN P; LOW DENSITY LIPOPROTEIN; MESSENGER RNA; OCCLUDIN; PENICILLIN G POTASSIUM; STREPTOMYCIN SULFATE; VIRUS LARGE T ANTIGEN; VON WILLEBRAND FACTOR;

ACETYLATION; ANIMAL TISSUE; ANTIGEN EXPRESSION; APICAL MEMBRANE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CAPILLARY; CAPILLARY ENDOTHELIUM; CELL GROWTH; CELL IMMORTALIZATION; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME LOCALIZATION; FEMALE; GENE EXPRESSION; GENE TRANSFER; GLUCOSE TRANSPORT SYSTEM; IN VITRO STUDY; MALE; MICHAELIS CONSTANT; MODEL; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIMIAN VIRUS 40; TEMPERATURE; TEMPERATURE SENSITIVITY; TIGHT JUNCTION; TIME; TRANSGENIC ANIMAL; WESTERN BLOTTING;

EID: 0034452792     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.3109/10611860008997912     Document Type: Article

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