The role of NK cell recognition of nectin and nectin-like proteins in tumor immunosurveillance

Seminars in Cancer Biology

Volumn 16, Issue 5, 2006, Pages 359-366

  Fuchs, Anja ^a   Colonna, Marco ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD226 ANTIGEN; CD96 ANTIGEN; CELL ADHESION MOLECULE; CLASS I RESTRICTED T CELL ASSOCIATED MOLECULE; IMMUNOGLOBULIN RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN; NATURAL KILLER CELL RECEPTOR; NCL 5 PROTEIN; NECTIN; NECTIN 2; NECTIN LIKE PROTEIN; T LYMPHOCYTE ANTIGEN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANTIGEN PRESENTING CELL; CANCER INHIBITION; CANCER INVASION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL ADHESION; CELL FUNCTION; CELL INTERACTION; CELL SURFACE; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; HUMAN; IMMUNOSURVEILLANCE; LUNG CANCER; MALIGNANT TRANSFORMATION; METASTASIS; MOLECULAR INTERACTION; NATURAL KILLER CELL; NEUROBLASTOMA; NONHUMAN; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVIEW; T CELL LEUKEMIA; T LYMPHOCYTE ACTIVATION; TUMOR CELL; TUMOR GROWTH; TUMOR IMMUNITY; TUMOR SUPPRESSOR GENE;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CELL ADHESION MOLECULES; HUMANS; IMMUNOGLOBULINS; IMMUNOLOGIC SURVEILLANCE; KILLER CELLS, NATURAL; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; NEOPLASMS; RECEPTORS, VIRUS; TUMOR ESCAPE;

EID: 33748170117     PISSN: 1044579X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semcancer.2006.07.002     Document Type: Review

References (54)

1. Karre K., Ljunggren H.G., Piontek G., and Kiessling R. Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy. Nature 319 6055 (1986) 675-678
2. Lanier L.L. NK cell recognition. Annu Rev Immunol 23 (2005) 225-274
3. Hildreth J.E., Gotch F.M., Hildreth P.D., and McMichael A.J. A human lymphocyte-associated antigen involved in cell-mediated lympholysis. Eur J Immunol 13 3 (1983) 202-208
4. Spits H., Keizer G., Borst J., Terhorst C., Hekman A., and de Vries J.E. Characterization of monoclonal antibodies against cell surface molecules associated with cytotoxic activity of natural and activated killer cells and cloned CTL lines. Hybridoma 2 4 (1983) 423-437
5. Gahmberg C.G. Leukocyte adhesion: CD11/CD18 integrins and intercellular adhesion molecules. Curr Opin Cell Biol 9 5 (1997) 643-650
6. Takai Y., Irie K., Shimizu K., Sakisaka T., and Ikeda W. Nectins and nectin-like molecules: roles in cell adhesion, migration, and polarization. Cancer Sci 94 8 (2003) 655-667
7. Burns G.F., Triglia T., Werkmeister J.A., Begley C.G., and Boyd A.W. TLiSA1, a human T lineage-specific activation antigen involved in the differentiation of cytotoxic T lymphocytes and anomalous killer cells from their precursors. J Exp Med 161 5 (1985) 1063-1078
8. Scott J.L., Dunn S.M., Jin B., et al. Characterization of a novel membrane glycoprotein involved in platelet activation. J Biol Chem 264 23 (1989) 13475-13482
9. Shibuya A., Campbell D., Hannum C., et al. DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes. Immunity 4 6 (1996) 573-581
10. Shibuya A., Lanier L.L., and Phillips J.H. Protein kinase C is involved in the regulation of both signaling and adhesion mediated by DNAX accessory molecule-1 receptor. J Immunol 161 4 (1998) 1671-1676
11. Shibuya K., Lanier L.L., Phillips J.H., et al. Physical and functional association of LFA-1 with DNAM-1 adhesion molecule. Immunity 11 5 (1999) 615-623
12. Ralston K.J., Hird S.L., Zhang X., et al. The LFA-1-associated molecule PTA-1 (CD226) on T cells forms a dynamic molecular complex with protein 4.1G and human discs large. J Biol Chem 279 32 (2004) 33816-33828
13. Bottino C., Castriconi R., Pende D., et al. Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule. J Exp Med 198 4 (2003) 557-567
14. Reymond N., Imbert A.M., Devilard E., et al. DNAM-1 and PVR regulate monocyte migration through endothelial junctions. J Exp Med 199 10 (2004) 1331-1341
15. Dardalhon V., Schubart A.S., Reddy J., et al. CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions. J Immunol 175 3 (2005) 1558-1565
16. Shibuya K., Shirakawa J., Kameyama T., et al. CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation. J Exp Med 198 12 (2003) 1829-1839
17. Tao D., Shangwu L., Qun W., et al. CD226 expression deficiency causes high sensitivity to apoptosis in NK T cells from patients with systemic lupus erythematosus. J Immunol 174 3 (2005) 1281-1290
18. Mendelsohn C.L., Wimmer E., and Racaniello V.R. Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily. Cell 56 5 (1989) 855-865
19. Nobis P., Zibirre R., Meyer G., Kuhne J., Warnecke G., and Koch G. Production of a monoclonal antibody against an epitope on HeLa cells that is the functional poliovirus binding site. J Gen Virol 66 Pt 12 (1985) 2563-2569
20. Irie K., Shimizu K., Sakisaka T., Ikeda W., and Takai Y. Roles and modes of action of nectins in cell-cell adhesion. Semin Cell Dev Biol 15 6 (2004) 643-656
21. Lange R., Peng X., Wimmer E., Lipp M., and Bernhardt G. The poliovirus receptor CD155 mediates cell-to-matrix contacts by specifically binding to vitronectin. Virology 285 2 (2001) 218-227
22. Masson D., Jarry A., Baury B., et al. Overexpression of the CD155 gene in human colorectal carcinoma. Gut 49 2 (2001) 236-240
23. Sloan K.E., Eustace B.K., Stewart J.K., et al. CD155/PVR plays a key role in cell motility during tumor cell invasion and migration. BMC Cancer 4 (2004) 73
24. Freistadt M.S., and Eberle K.E. Physical association between CD155 and CD44 in human monocytes. Mol Immunol 34 18 (1997) 1247-1257
25. Oda T., Ohka S., and Nomoto A. Ligand stimulation of CD155alpha inhibits cell adhesion and enhances cell migration in fibroblasts. Biochem Biophys Res Commun 319 4 (2004) 1253-1264
26. Castriconi R., Dondero A., Corrias M.V., et al. Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: critical role of DNAX accessory molecule-1-poliovirus receptor interaction. Cancer Res 64 24 (2004) 9180-9184
27. Pende D., Spaggiari G.M., Marcenaro S., et al. Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112). Blood 105 5 (2005) 2066-2073
28. Tahara-Hanaoka S., Miyamoto A., Hara A., Honda S., Shibuya K., and Shibuya A. Identification and characterization of murine DNAM-1 (CD226) and its poliovirus receptor family ligands. Biochem Biophys Res Commun 329 3 (2005) 996-1000
29. Tahara-Hanaoka S., Shibuya K., Kai H., et al. Tumor rejection by the poliovirus receptor family ligands of the DNAM-1 (CD226) receptor. Blood 107 4 (2006) 1491-1496
30. Wang P.L., O'Farrell S., Clayberger C., and Krensky A.M. Identification and molecular cloning of tactile. A novel human T cell activation antigen that is a member of the Ig gene superfamily. J Immunol 148 8 (1992) 2600-2608
31. Gramatzki M., Ludwig W.D., Burger R., et al. Antibodies TC-12 ("unique") and TH-111 (CD96) characterize T-cell acute lymphoblastic leukemia and a subgroup of acute myeloid leukemia. Exp Hematol 26 13 (1998) 1209-1214
32. Fuchs A., Cella M., Giurisato E., Shaw A.S., and Colonna M. Cutting edge: CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155). J Immunol 172 7 (2004) 3994-3998
33. Boles K.S., Barchet W., Diacovo T., Cella M., and Colonna M. The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM. Blood 106 3 (2005) 779-786
34. Kennedy J., Vicari A.P., Saylor V., et al. A molecular analysis of NKT cells: identification of a class-I restricted T cell-associated molecule (CRTAM). J Leuk Biol 67 5 (2000) 725-734
35. Galibert L., Diemer G.S., Liu Z., et al. Nectin-like protein 2 defines a subset of T-cell zone dendritic cells and is a ligand for class-I-restricted T-cell-associated molecule. J Biol Chem 280 23 (2005) 21955-21964
36. Patino-Lopez G., Hevezi P., Lee J., et al. Human class-I restricted T cell associated molecule is highly expressed in the cerebellum and is a marker for activated NKT and CD8+ T lymphocytes. J Neuroimmunol 171 1-2 (2006) 145-155
37. Arase N., Takeuchi A., Unno M., et al. Heterotypic interaction of CRTAM with Necl2 induces cell adhesion on activated NK cells and CD8+ T cells. Int Immunol 17 9 (2005) 1227-1237
38. Wolk K., Kunz S., Witte E., Friedrich M., Asadullah K., and Sabat R. IL-22 increases the innate immunity of tissues. Immunity 21 2 (2004) 241-254
39. Kuramochi M., Fukuhara H., Nobukuni T., et al. TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer. Nat Genet 27 4 (2001) 427-430
40. Yageta M., Kuramochi M., Masuda M., et al. Direct association of TSLC1 and DAL-1, two distinct tumor suppressor proteins in lung cancer. Cancer Res 62 18 (2002) 5129-5133
41. Shingai T., Ikeda W., Kakunaga S., et al. Implications of nectin-like molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein localization in epithelial cells. J Biol Chem 278 37 (2003) 35421-35427
42. Fukuhara H., Masuda M., Yageta M., et al. Association of a lung tumor suppressor TSLC1 with MPP3, a human homologue of Drosophila tumor suppressor Dlg. Oncogene 22 40 (2003) 6160-6165
43. Biederer T., Sara Y., Mozhayeva M., et al. SynCAM, a synaptic adhesion molecule that drives synapse assembly. Science 297 5586 (2002) 1525-1531
44. Murakami Y. Involvement of a cell adhesion molecule, TSLC1/IGSF4, in human oncogenesis. Cancer Sci 96 9 (2005) 543-552
45. Mao X., Seidlitz E., Ghosh K., Murakami Y., and Ghosh H.P. The cytoplasmic domain is critical to the tumor suppressor activity of TSLC1 in non-small cell lung cancer. Cancer Res 63 22 (2003) 7979-7985
46. Mao X., Seidlitz E., Truant R., Hitt M., and Ghosh H.P. Re-expression of TSLC1 in a non-small-cell lung cancer cell line induces apoptosis and inhibits tumor growth. Oncogene 23 33 (2004) 5632-5642
47. Sasaki H., Nishikata I., Shiraga T., et al. Overexpression of a cell adhesion molecule, TSLC1, as a possible molecular marker for acute-type adult T-cell leukemia. Blood 105 3 (2005) 1204-1213
48. Dunn G.P., Old L.J., and Schreiber R.D. The three Es of cancer immunoediting. Annu Rev Immunol 22 (2004) 329-360
49. Baury B., Masson D., McDermott Jr. B.M., et al. Identification of secreted CD155 isoforms. Biochem Biophys Res Commun 309 1 (2003) 175-182
50. Ebnet K., Suzuki A., Ohno S., and Vestweber D. Junctional adhesion molecules (JAMs): more molecules with dual functions?. J Cell Sci 117 Pt 1 (2004) 19-29
51. Grundemann C., Bauer M., Schweier O., et al. Cutting edge: identification of E-cadherin as a ligand for the murine killer cell lectin-like receptor G1. J Immunol 176 3 (2006) 1311-1315
52. Ito M., Maruyama T., Saito N., Koganei S., Yamamoto K., and Matsumoto N. Killer cell lectin-like receptor G1 binds three members of the classical cadherin family to inhibit NK cell cytotoxicity. J Exp Med 203 2 (2006) 289-295
53. Markel G., Lieberman N., Katz G., et al. CD66a interactions between human melanoma and NK cells: a novel class I MHC-independent inhibitory mechanism of cytotoxicity. J Immunol 168 6 (2002) 2803-2810
54. Stern N., Markel G., Arnon T.I., et al. Carcinoembryonic antigen (CEA) inhibits NK killing via interaction with CEA-related cell adhesion molecule 1. J Immunol 174 11 (2005) 6692-6701