Mitochondria-mediated apoptosis in human breast carcinoma MCF-7 cells induced by a novel selenadiazole derivative

Biomedicine and Pharmacotherapy

Volumn 62, Issue 2, 2008, Pages 77-84

  Chen, Tianfeng ^a   Zheng, Wenjie ^b   Wong, Yum Shing ^a   Yang, Fang ^b  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b JINAN UNIVERSITY   (China)

Author keywords

Apoptosis; Mitochondrial dysfunction; Reactive oxygen species; Selenadiazole derivative; Selenium

Indexed keywords

1,2,3 SELENADIAZOLE DERIVATIVE; 1,2,5 SELENADIAZOLO[3,4 D]PYRIMIDINE 5,7(4H,6H) DIONE; CASPASE 8; CASPASE 9; DNA FRAGMENT; ORGANOSELENIUM DERIVATIVE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST CARCINOMA; CANCER PREVENTION; CELL PROLIFERATION; CONTROLLED STUDY; DNA DETERMINATION; DRUG POTENCY; ENZYME ACTIVATION; HEPATOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRACELLULAR TRANSPORT; MELANOMA CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CASPASE 8; CASPASE 9; CELL LINE, TUMOR; DNA FRAGMENTATION; FEMALE; G1 PHASE; GENE EXPRESSION REGULATION; HUMANS; LIVER NEOPLASMS; MELANOMA; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRIMIDINONES; REACTIVE OXYGEN SPECIES;

EID: 38949104369     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2007.12.002     Document Type: Article

References (29)

1. Sinha R., and El-Bayoumy K. Apoptosis is a critical cellular event in cancer chemoprevention and chemotherapy by selenium compounds. Curr Cancer Drug Targets 4 (2004) 13-28
2. Clark L.C., Combs G.F.J., Turnbull B.W., Slate E.H., Chalker D.K., Chow J., et al. Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional prevention of cancer study group. JAMA 276 (1996) 1957-1963
3. Yu S.Y., Zhu Y.J., and Li W.G. Protective role of selenium against hepatitis B virus and primary liver cancer in Qidong. Biol Trace Elem Res 56 (1997) 117-124
4. El-Bayoumy K., and Sinha R. Mechanisms of mammary cancer chemoprevention by organoselenium compounds. Mutat Res 551 (2004) 181-197
5. Abdulah R., Miyazaki K., Nakazawa M., and Koyama H. Chemical forms of selenium for cancer prevention. J Trace Elem Med Biol 19 (2005) 141-150
6. Zhao R., Xiang N., Domann F.E., and Zhong W. Expression of p53 enhances selenite-induced superoxide production and apoptosis in human prostate cancer cells. Cancer Res 66 (2006) 2296-2304
7. Mugesh G., Mont W.W., and Sies H. Chemistry of biologically important synthetic organoselenium compounds. Chem Rev 101 (2001) 2125-2179
8. Juang S.H., Lung C.C., Hsu P.C., Hsu K.S., Li Y.C., Hong P.C., et al. D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation. Mol Cancer Ther 6 (2007) 193-202
9. Al-Smadi M., and Ratrout S. New multi-1,2,3-selenadiazole aromatic derivatives. Molecules 10 (2005) 1126-1134
10. Ito H., Wang J.Z., Shimura K., Sakakibara J., and Ueda T. Antitumor effect of a new organic selenium compound, 6-phenyl-7 (6H)-isoselenazolo [4,3-d] pyrimidone (ISP), on the growth of P388 mouse leukemia. Anticancer Res 10 (1990) 891-895
11. Kumar Y., Green R., Borysko K.Z., Wise D.S., Wotring L.L., and Townsend L.B. Synthesis of 2,4-disubstituted thiazoles and selenazoles as potential antitumor and antifilarial agents: 1. Methyl 4-(isothiocyanatomethyl) thiazole-2-carbamates,-selenazole-2-carbamates, and related derivatives. J Med Chem 36 (1993) 3843-3848
12. Grivas S. 2,1,3-Benzoselenadiazoles as valuable synthetic intermediates. Curr Org Chem 4 (2000) 707-726
13. Jaliliana A.R., Sattarib S., Bineshmarvastia M., Daneshtalabb M., and Shafiee A. Synthesis and in vitro antifungal and cytotoxicity evaluation of substituted 4,5-dihydronaphtho[1,2-d] [1,2,3] thia (or selena) diazoles. II Farmaco 58 (2003) 63-68
14. Arsenyan P., Rubina K., Shestakova I., and Domracheva I. 4-Methyl-1,2,3-selenadiazole-5-carboxylic acid amides: antitumor action and cytotoxic effect correlation. Eur J Med Chem 42 (2007) 635-640
15. Zou J.H., Yang F., Zheng W.J., Bai Y., and Li Y.Q. Solid-phase synthesis of heterocyclic aromatic selenium compounds. Chem Reagents 26 (2004) 289-292
16. Zhang J.L., Zheng W.J., Zou J.H., Yang F., Bai Y., and Li Y.Q. Solid-state synthesis of heterocyclic aromatic selenium compounds at room temperature. Chem J Int 6 (2004) 97
17. Zhang J.L., Zou J.H., Zheng W.J., Yang F., Bai Y., and Li Y.Q. Microwave solid-state synthesis of heterocyclic aromatic selenium compounds. Chem Res Appl 16 (2004) 561-562
18. Zou J.H., Zheng W.J., Yang F., Zen X.H., Bai Y., and Li Y.Q. GC/MS analysis of heterocyclic aromatic selenium compounds. J Anal Sci 21 (2005) 381-383
19. Mesner J.P.W., and Kaufmann S.H. Methods utilized in the study of apoptosis. Adv Pharmacol 41 (1997) 57-87
20. Gurp M.V., Festjens N., Loo G.V., Saelens X., and Vandenabeele P. Mitochondrial intermembrane proteins in cell death. Biochem Biophys Res Commun 304 (2003) 487-497
21. Evan G., and Littlewood T. A matter of life and cell death. Science 281 (1998) 1317-1322
22. Kim R. Recent advances in understanding the cell death pathways activated by anticancer therapy. Cancer 103 (2005) 1551-1560
23. Zapata J.M., Pawlowski K., Haas E., Ware C.F., Godzik A., and Reed J.C. A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains. J Biol Chem 276 (2001) 24242-24252
24. Cory S., and Adams J.M. The Bcl-2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2 (2002) 647-656
25. Turrens J.F. Mitochondrial formation of reactive oxygen species. J Physiol 552 (2003) 335-344
26. Dhanasekaran A., Kotamraju S., Karunakaran C., Kalivendi S.V., Thomas S., Joseph J., et al. Mitochondria superoxide dismutase mimetic inhibits peroxide-induced oxidative damage and apoptosis: role of mitochondrial superoxide. Free Radic Biol Med 39 (2005) 567-583
27. Apel K., and Hirt H. Reactive oxygen species: metabolism, oxidative stress, and signal transduction. Annu Rev Plant Biol 55 (2004) 373-399
28. Pelicanoa H., Carneya D., and Huang P. ROS stress in cancer cells and therapeutic implications. Drug Resist Update 7 (2004) 97-110
29. Nilsonne G., Sun X., Nystrom C., Rundlof A.K., Fernandes A.P., Bjornstedt M., et al. Selenite induces apoptosis in sarcomatoid malignant mesothelioma cells through oxidative stress. Free Radic Biol Med 6 (2006) 874-885