Anticarcinogenic effects of selenium

Cellular and Molecular Life Sciences

Volumn 57, Issue 13-14, 2000, Pages 1864-1873

  Schrauzer, G N ^a,b  

^a Biological Trace Element Research Institute   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cancer; Cancer prevention; Selenium; Selenium antagonists; Selenium supplementation

Indexed keywords

ANTIMUTAGENIC AGENT; CELL DNA; GLUTATHIONE PEROXIDASE; OXYGEN RADICAL; SELENIUM;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CANCER PREVENTION; CANCER RISK; CELL DIVISION; DIET SUPPLEMENTATION; DRUG EFFECT; DRUG MECHANISM; GENE ACTIVATION; GENE INACTIVATION; HUMAN; IMMUNE SYSTEM; LIFESTYLE; MALIGNANT TRANSFORMATION; NUTRITIONAL VALUE; ONCOGENE; REVIEW; RISK FACTOR;

EID: 0034485903     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00000668     Document Type: Review

References (123)

1. Possible inhibitory effect of selenium on human cancer
2. Interpretation of the methylene blue reduction test of human plasma and the possible cancer protecting effect of selenium
3. Selenium distribution and human cancer mortality
4. Selenium and cancer: Chemical interpretation of a plasma "cancer test"
5. Cancer mortality correlation studies. III. Associations with dietary selenium intakes
6. Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin
7. Selenium vitamin E and prostate cancer: Ready for prime time?
8. Selenium inhibition of chemical carcinogenesis
9. Effect of selenium on virally induced and transplantable tumor models
10. The distribution of selenium and cancer mortality in the continental United States
11. Regional variation of cancer mortality incidence and its relation to selenium levels in China
12. Antioxidant status and cancer mortality in China
13. Blood selenium concentration in residents of areas in China having a high incidence of lung cancer
14. Blood serum selenium in the province of Merida, Venezuela, related to sex, cancer incidence and soil selenium
15. Selenium in forage crops and cancer mortality in U.S. counties
16. Selenium in human nutrition: Dietary intakes and effects of supplementation
17. Selenium balance in young men during selenium depletion and repletion
18. Prediagnostic serum selenium and risk of cancer
19. Association between serum selenium and the risk of cancer
20. Low plasma selenium as a risk factor for cancer in middle aged men
21. Serum selenium contents and the risk of cancer
22. Selenium in the human thyroid gland
23. Prediagnostic serum selenium in a case-control study of thyroid cancer
24. Selenium therapy in patients with precancerous and malignant oral cavity lesions: Preliminary results
25. Plasma selenium and the risk of colorectal adenomas
26. Serum selenium and vitamin E concentrations in patients with lung cancer and their families
27. A prospective cohort study on selenium status and the risk of lung cancer
28. A prospective study on toenail selenium levels and risk of gastrointestinal cancer
29. Study of prediagnostic selenium level in toenails and the risk of advanced prostate cancer
30. Selenoprotein P in serum as a biochemical marker of selenium status
31. Plasma selenoprotein P levels of healthy males in different selenium status after oral supplementation with different forms of selenium
32. Selenoprotein P in plasma in relation to cancer morbidity in middle-aged Swedish men
33. The relationship of dietary selenium and breast cancer
34. Levels of selenium in plasma and glutathione peroxidase in erythrocytes and risk of breast cancer. A case-control study
35. Oxidant and antioxidant levels in the erythrocytes of breast cancer patients treated with CMF
36. Erythrocyte selenium and breast cancer risk
37. Selenium levels in nails of premenopausal breast cancer patients assessed prediagnostically in a cohort-nested case-referent study among women screened in the DOM project
38. A prospective study of selenium status and breast cancer risk
39. Selenium in diet, blood, and toenails in relation to breast cancer: A case control study
40. Selenium in the blood of Japanese and American women with and without breast cancer and fibrocystic disease
41. Protective role of selenium against hepatitis B virus and primary liver cancer in Qidong
42. A preliminary report of the intervention trials of primary liver cancer in high risk populations with nutritional supple-mentation of selenium in China
43. Chemoprevention trial of human hepatitis with selenium supplementation in China
44. Nutrition intervention trials in Linxian, China: Supplementation with specific vitamin/mineral combinations, and disease-specific mortality in the general population
45. Selenomethionine and selenium yeast: Appropriate forms of selenium for use in infant formulas and nutritional supplements
46. Nutrition and breast cancer in Japan
47. Analysis of dietary fat, calories, body weight and the development of mammary tumors in rats and mice: A review
48. Dietary fat and breast cancer: A quantitative assessment of the epidemiological literature and a discussion of methodological issues
49. Soybean phytoestrogen intake and cancer risk (1995)
50. Phytooestrogens and breast cancer
51. Serum and tissue lycopene and biomarkers of oxidation in prostate cancer patients
52. Diet, antioxidants and risk of cancer: A case control study
53. Selenium, dietary fats and male lung cancer mortality
54. Enhancement of mammary tumorigenesis by dietary selenium deficiency in rats with a high polyunsaturated fat intake
55. Selenium and the genesis of murine mammary tumors
56. Effect of simulated American, Bulgarian and Japanese human diets and of selenium supplementation on the incidence of virally induced mammary tumors in female mice
57. Dietary selenium, glutathione peroxidase activity and toxicity of 2,3,7,8-tetradichlorobenzo-p-dioxin
58. Cancer incidence rates among Japanese immigrants in the City of Sao Paulo, Brazil, 1968-78
59. Serum selenium levels in middle-aged Japanese men in Sao Paulo, Brazil, and five areas of Japan
60. Cadmium
61. The metals
62. The geographical distribution of high cadmium concentrations in the environment and prostate cancer in Alberta
63. Correlations between carcinogenic trace metals in water supplies and cancer mortality
64. Cancer mortality correlation studies. IV. Associations with dietary intakes and blood levels of certain trace elements, notably Se-antagonists
65. Metabolic balance of zinc copper cadmium iron molybdenum and selenium in young New Zealand women
66. Cadmium-induced excretion of urinary lipid metabolites, DNA damage, glutathione depletion and hepatic lipid peroxidation in Sprague-Dawley rats
67. Cadmium and selenium in blood and urine related to smoking habits and previous exposure to mercury vapor
68. Selenium protection against testicular lipid peroxidation from cadmium
69. Effects of selenium antagonists on cancer susceptibility: New aspects of chronic heavy metal toxicity
70. Antioxidants and cancer. VIII. Cadmium-selenium levels in kidneys
71. Zinc and cadmium analysis of human prostate neoplasms
72. Selenium prevents the growth stimulatory effects of cadmium on human prostatic epithelium
73. Effects of dietary selenium and lead on the genesis of spontaneous mammary tumors in mice
74. Inhibition of the genesis of spontaneous mammary tumors in C3H mice: Effects of Se and of Se-antagonistic elements and their possible role in human breast cancer
75. In vivo interaction of selenium with zinc
76. Zinc-selenium interaction in the rat
77. 75Se
78. Zinc distribution in malignant tumors
79. Relationship between tumor and trace elements in hair
80. Epidemiological associations between arsenic and cancer in Argentina
81. Malignant neoplasms among residents of a Blackfoot disease-endemic area in Taiwan: High-arsenic artesian well water and cancers
82. Arsenic, selenium and zinc in patients with Blackfoot disease
83. A study of the relation of the Se/As ratio in the hair of workers to lung cancer at the Yunnan Tin Mine
84. Intervention trial with selenium for the prevention of lung cancer among tin miners in Yunnan
85. Arsenic and cancer. Effects of the joint administration of selenium and arsenic on the genesis of spontaneous mammary tumors in mice
86. Interaction between selenium and chromium and distribution of zinc, rubidium, cobalt and iron in mice given chromate ions and selenium compounds
87. Trace elements in carcinogenesis
88. Trace element correlations in the blood of Indian women with breast cancer
89. Minor and trace elemental contents of cancerous breast tissue measured by instrumental and radiochemical neutron activation analysis
90. Distribution of trace elements in normal and neoplastic human tissues by energy dispersive x-ray fluorescence
91. Inorganic element levels in neoplasia
92. Selenium and other trace elements in lung tissue in smelter workers. Relationship to the occurrence of lung cancer
93. Benign human enterovirs becomes virulent in selenium-deficient mice
94. Genomic structures of viral agents in relation to the biosynthesis of selenoproteins
95. Effects of temporary selenium supplementation on the genesis of mammary tumors in female inbred C3H/St mice
96. Selenite: A good inhibitor of rat liver DNA methylase
97. The site of substitution of the methyl group in the bioalkylation of benzo-[a]-pyrene
98. The role of hypoxia in selenium metabolism
99. Selenium: Mechanistic aspects of anticarcinogenic action
100. Sauerstoff und Selen in der Onkologie
101. Effects of selenium on cell proliferation in rat liver and mammalian cells as indicated by cytokinetic and biochemical analysis
102. On the nature of selenium toxicity and carcinostatic activity
103. Biological efficacy of partial hepatectomy and hepatopoietin in long-term selenium-deficienc mice
104. Biochemical and cellular aspects of the anticancer activity of selenium
105. Differential effects of selenium on the proliferation of human pulmonary adenocarcinoma cells and human embryonic lung diploid cells in vitro
106. Inhibition of cell colony formation by selenite: Involvement of glutathione
107. The selenium metabolite selenodiglutathione induces p53 and apoptosis: Relevance to the chemopreventive effects of selenium?
108. Mechanism of the regulation of thioredoxin reductase activity in cancer cells by the chemopreventive agent selenium
109. Selenium: Inhibition of microtubule formation and interaction with tubulin
110. The regulatory effect of selenium on the expression of oncogenes associated with the proliferation and differentiation on tumor cells
111. Selenite supplementation decreases the expression of MAZ in HT29 human colon adenocarcinoma cells
112. Finger-loops, oncogenes and metals
113. Selenium-mediated inhibition of transcription factor nFκB and HIV-1 LTR promoter activity
114. Redox regulation of nFκB activation
115. Inhibition of nuclear factor κB activation confers sensitivity to tumor necrosis factor-α by impairment of cell cycle progression in human glioma cells
116. Selenium and immune responses. A review
117. Selenium and immune cell functions. I. Effect on lymphocyte proliferation and production of interleukin-1 and interleukin-2
118. Selenium and immune cell functions. II. Effect on lymphocyte-mediated cytotoxicity
119. Supplementation with selenium and human immune cell functions. I. Effect on lymphocyte proliferation and interleukin 2 receptor expression
120. Supplementation with selenium and human immune cell functions. II. Effect on cytotoxic lymphocytes and natural killer cells
121. Supplementation with selenium augments the functions of natural killer and lymphokine-activated killer cells