Residues that affect human Argonaute2 concentration in cytoplasmic processing bodies

Biochemical and Biophysical Research Communications

Volumn 378, Issue 3, 2009, Pages 620-624

  Zhou, Huamin ^a   Yang, Lin ^b   Li, Hanjie ^a   Li, Linjie ^a   Chen, Jianming ^a  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Argonaute2 (Ago2); Co localization; Dcp1a; Processing bodies (P bodies)

Indexed keywords

ARGONAUTE 2 PROTEIN; CHIMERIC PROTEIN; PROTEIN DCP1A; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOPLASM; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN LOCALIZATION; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; CYTOPLASM; ENDORIBONUCLEASES; EUKARYOTIC INITIATION FACTOR-2; EVOLUTION, MOLECULAR; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; POINT MUTATION; RNA-INDUCED SILENCING COMPLEX; TRANS-ACTIVATORS;

EUKARYOTA; HEXAPODA; MAMMALIA;

EID: 57749202244     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.11.098     Document Type: Article

References (31)

1. Meister G., and Tuschl T. Mechanisms of gene silencing by double-stranded RNA. Nature 431 (2004) 343-349
2. Meyer S., Temme C., and Wahle E. Messenger RNA turnover in eukaryotes: pathways and enzymes. Crit. Rev. Biochem. Mol. Biol. 39 (2004) 197-216
3. Teixeira D., Sheth U., Valencia-Sanchez M.A., Brengues M., and Parker R. Processing bodies require RNA for assembly and contain nontranslating mRNAs. RNA 11 (2005) 371-382
4. Cougot N., Babajko S., and Séraphin B. Cytoplasmic foci are sites of mRNA decay in human cells. J. Cell Biol. 165 (2004) 31-40
5. Sheth U., and Parker R. Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science 300 (2003) 805-808
6. Hannon G.J. RNA interference. Nature 418 (2002) 244-251
7. Meister G., Landthaler M., Patkaniowska A., Dorsett Y., Teng G., and Tusch T. Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol. Cell 15 (2004) 185-197
8. Hammond S.M., Boettcher S., Caudy A.A., Kobayashi R., and Hannon G.J. Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 293 (2001) 1146-1150
9. Rand T.A., Ginalski K., Grishin N.V., and Wang X. Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity. PNAS 101 (2004) 14385-14389
10. Doi N., Zenno S., Ueda R., Ohki-Hamazaki H., Ui-Tei K., and Saigo K. Short- interfering-RNA-mediated gene silencing in mammalian cells requires dicer and eif2c translation initiation factors. Curr. Biol. 13 (2003) 41-46
11. Rivas F.V., Tolia N.H., Song J.J., Aragon J.P., Liu J., Hannon G.J., and Joshua-Tor L. Purified Argonaute2 and a siRNA form recombinant human RISC. Nat. Struct. Mol. Biol. 12 (2005) 340-349
12. Sen G.L., and Blau H.M. Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies. Nat. Cell Biol. 7 (2005) 633-636
13. Liu J., Carmell M.A., Rivas F.V., Marsden C.G., Thomson J.M., Song J., Hammond S.M., Joshua-Tor L., and Hannon G.J. Argonaute2 is the catalytic engine of mammalian RNAi. Science 305 (2004) 1437-1441
14. Carmell M.A., and Hannon G.J. RNase III enzymes and the initiation of gene silencing. Nat. Struct. Mol. Biol. 11 (2004) 214-218
15. Hutvágner G., and Zamore P.D. A microRNA in a multiple-turnover RNAi enzyme complex. Science 297 (2002) 2056-2060
16. Gregory R.I., Chendrimada T.P., Cooch N., and Shiekhattar R. Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 123 (2005) 631-640
17. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116 (2004) 281-297
18. Liu J., Valencia-Sanchez M.A., Hannon G.J., and Parker R. MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nat. Cell Biol. 7 (2005) 717-723
19. Mourelatos Z., Dostie J., Paushkin S., Sharma A., Charroux B., Abel L., Rappsilber J., Mann M., and Dreyfuss G. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev. 16 (2002) 720-728
20. Jing Q., Huang S., Guth S., Zarubin T., Motoyama A., Chen J., Di Padova F., Lin S., Gram H., and Han J. Involvement of microRNA in AU-rich element-mediated mRNA instability. Cell 120 (2005) 623-634
21. Carmell M.A., Xuan Z., Zhang M.Q., and Hannon G.J. The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis. Genes Dev. 16 (2002) 2733-2742
22. Cerutti L., Mian N., and Bateman A. Domains in gene silencing and cell differentiation proteins: the novel PAZ domain and redefinition of the Piwi domain. Trends Biochem. Sci. 25 (2000) 481-482
23. Sasaki T., Shiohama A., Minoshima S., and Shimizu N. Identification of eight members of the Argonaute family in the human genome. Genomics 82 (2003) 323-330
24. Parker J.S., and Barford D. Argonaute: a scaffold for the function of short regulatory RNAs. Trends Biochem. Sci. 31 (2006) 622-630
25. Song J., Liu J., Tolia N.H., Schneiderman J., Smith S.K., Martienssen R.A., Hannon G.J., and Joshua-Tor L. The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complex. Nat. Struct. Biol. 10 (2003) 1026-1032
26. Ma J., Ye K., and Patel D.J. Structural basis for overhangspecific small interfering RNA recognition by the PAZ domain. Nature 429 (2004) 318-322
27. Liu J., Valencia-Sanchez M.A., Hannon G.J., and Parker R. MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nat. Cell Biol. 7 (2005) 719-723
28. Xin Y., Lasker J.M., Rosman A.S., and Lieber C.S. Isoelectric focusing/western blotting: a novel and practical method for quantitation of carbohydrate-deficient transferrin in alcoholics. Alcohol. Clin. Exp. Res. 15 (2006) 814-821
29. Zeng Y., Sankala H., Zhang X., and Graves P.R. Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies. Biochem. J. 413 (2008) 429-436
30. Blom N., Gammeltoft S., and Brunak S. Sequence- and structure-based prediction of eukaryotic protein phosphorylation sites. J. Mol. Biol. 294 (1999) 1351-1362
31. Y. Wang, G. Sheng, S. Juranek, T. Tushl, D. Patel, Structure of the guide-strand-containing argonaute silencing complex, Nature 455 (2008), advance online publication.