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Volumn 1147, Issue , 2008, Pages 335-347

Regulation of forkhead transcription factor FoxO3a contributes to calorie restriction-induced prevention of Alzheimer's disease-type amyloid neuropathology and spatial memory deterioration

Author keywords

Alzheimer's disease; Amyloid peptide; Calorie restriction; Forkhead transcription factor FoxO3a

Indexed keywords

ALPHA SECRETASE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; RHO KINASE; SIRTUIN 1; TRANSCRIPTION FACTOR FKHRL1;

EID: 57649155899     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1427.024     Document Type: Conference Paper
Times cited : (92)

References (28)
  • 1
    • 14844293962 scopus 로고    scopus 로고
    • The role of insulin and IGF-1 signaling in longevity
    • &
    • Katic, M. & C.R. Kahn. 2005. The role of insulin and IGF-1 signaling in longevity. Cell. Mol. Life Sci. 62 : 320 343.
    • (2005) Cell. Mol. Life Sci. , vol.62 , pp. 320-343
    • Katic, M.1    Kahn, C.R.2
  • 2
    • 2942536602 scopus 로고    scopus 로고
    • The paradox of the insulin/IGF-1 signaling pathway in longevity
    • &
    • Rincon, M., R. Muzumdar, G. Atzmon & N. Barzilai. 2004. The paradox of the insulin/IGF-1 signaling pathway in longevity. Mech. Ageing Dev. 125 : 397 403.
    • (2004) Mech. Ageing Dev. , vol.125 , pp. 397-403
    • Rincon, M.1    Muzumdar, R.2    Atzmon, G.3    Barzilai, N.4
  • 3
    • 0037323903 scopus 로고    scopus 로고
    • Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors
    • &
    • Birkenkamp, K.U. & P.J. Coffer. 2003. Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors. Biochem. Soc. Trans. 31 : 292 297.
    • (2003) Biochem. Soc. Trans. , vol.31 , pp. 292-297
    • Birkenkamp, K.U.1    Coffer, P.J.2
  • 4
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
    • Brunet, A., A. Bonni, M.J. Zigmond, et al. 1999. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96 : 857 868.
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1    Bonni, A.2    Zigmond, M.J.3
  • 5
    • 4143050290 scopus 로고    scopus 로고
    • The interaction between FOXO and SIRT1: Tipping the balance towards survival
    • &
    • Giannakou, M. & L. Partridge. 2004. The interaction between FOXO and SIRT1: tipping the balance towards survival. Trends Cell. Biol. 14 : 408 412.
    • (2004) Trends Cell. Biol. , vol.14 , pp. 408-412
    • Giannakou, M.1    Partridge, L.2
  • 6
    • 1342264308 scopus 로고    scopus 로고
    • Mammalian SIRT1 represses forkhead transcription factors
    • Motta, M.C., N. Divecha, M. Lemieux, et al. 2004. Mammalian SIRT1 represses forkhead transcription factors. Cell 116 : 551 563.
    • (2004) Cell , vol.116 , pp. 551-563
    • Motta, M.C.1    Divecha, N.2    Lemieux, M.3
  • 7
    • 3142742707 scopus 로고    scopus 로고
    • FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2 (SIRT1)
    • Van Der Horst, A., L.G. Tertoolen, L.M. de Vries-Smits, et al. 2004. FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2 (SIRT1). J. Biol. Chem. 279 : 28873 28879.
    • (2004) J. Biol. Chem. , vol.279 , pp. 28873-28879
    • Van Der Horst, A.1    Tertoolen, L.G.2    De Vries-Smits, L.M.3
  • 8
    • 3042750643 scopus 로고    scopus 로고
    • Silent information regulator 2 potentiates FoxO1-mediated transcription through its deacetylase activity
    • Daitoku, H., M. Hatta, H. Matsuzaki, et al. 2004. Silent information regulator 2 potentiates FoxO1-mediated transcription through its deacetylase activity. Proc. Natl. Acad. Sci. USA 101 : 10042 10047.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 10042-10047
    • Daitoku, H.1    Hatta, M.2    Matsuzaki, H.3
  • 9
    • 20144386977 scopus 로고    scopus 로고
    • Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease
    • Wang, J., L. Ho, W. Qin, et al. 2005. Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease. FASEB J. 19 : 659 661.
    • (2005) FASEB J. , vol.19 , pp. 659-661
    • Wang, J.1    Ho, L.2    Qin, W.3
  • 10
    • 33746824192 scopus 로고    scopus 로고
    • Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction
    • Qin, W., T. Yang, L. Ho, et al. 2006a. Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. J. Biol. Chem. 281 : 21745 21754.
    • (2006) J. Biol. Chem. , vol.281 , pp. 21745-21754
    • Qin, W.1    Yang, T.2    Ho, L.3
  • 11
    • 0029742199 scopus 로고    scopus 로고
    • Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
    • Hsiao, K., P. Chapman, S. Nilsen, et al. 1996. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274 : 99 102.
    • (1996) Science , vol.274 , pp. 99-102
    • Hsiao, K.1    Chapman, P.2    Nilsen, S.3
  • 12
    • 4644286910 scopus 로고    scopus 로고
    • Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease
    • Ho, L., W. Qin, P.N. Pompl, et al. 2004. Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease. FASEB J. 18 : 902 904.
    • (2004) FASEB J. , vol.18 , pp. 902-904
    • Ho, L.1    Qin, W.2    Pompl, P.N.3
  • 13
    • 0035980149 scopus 로고    scopus 로고
    • Insulin rescues retinal neurons from apoptosis by aphosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3
    • Barber, A.J., M. Nakamura, E.B. Wolpert, et al. 2001. Insulin rescues retinal neurons from apoptosis by aphosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3. J. Biol. Chem. 276 : 32814 32821.
    • (2001) J. Biol. Chem. , vol.276 , pp. 32814-32821
    • Barber, A.J.1    Nakamura, M.2    Wolpert, E.B.3
  • 14
    • 0032887341 scopus 로고    scopus 로고
    • Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2
    • Kelley, K.A., L. Ho, D. Winger, et al. 1999. Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2. Am. J. Pathol. 155 : 995 1004.
    • (1999) Am. J. Pathol. , vol.155 , pp. 995-1004
    • Kelley, K.A.1    Ho, L.2    Winger, D.3
  • 15
    • 14544282413 scopus 로고    scopus 로고
    • Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
    • Rodgers, J.T., C. Lerin, W. Haas, et al. 2005. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434 : 113 118.
    • (2005) Nature , vol.434 , pp. 113-118
    • Rodgers, J.T.1    Lerin, C.2    Haas, W.3
  • 16
    • 9144219644 scopus 로고    scopus 로고
    • Cyclooxygenase (COX)-2 and COX-1 potentiate beta-amyloid peptide generation through mechanisms that involve gamma-secretase activity
    • Qin, W., L. Ho, P.N. Pompl, et al. 2003. Cyclooxygenase (COX)-2 and COX-1 potentiate beta-amyloid peptide generation through mechanisms that involve gamma-secretase activity. J. Biol. Chem. 278 : 50970 50977.
    • (2003) J. Biol. Chem. , vol.278 , pp. 50970-50977
    • Qin, W.1    Ho, L.2    Pompl, P.N.3
  • 17
    • 0018344553 scopus 로고
    • Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat
    • Barnes, C.A. 1979. Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. J. Comp. Physiol. Psycho. 193 : 74 104.
    • (1979) J. Comp. Physiol. Psycho. , vol.193 , pp. 74-104
    • Barnes, C.A.1
  • 18
    • 0033082456 scopus 로고    scopus 로고
    • Adaptation of the circular platform spatial memory task for mice: Use in detecting cognitive impairment in the APPsw transgenic mouse model for Alzheimer's disease
    • Pompl, P.N., M.J. Mullan, K. Bjugstad, G.W. Arendash. 1999. Adaptation of the circular platform spatial memory task for mice: use in detecting cognitive impairment in the APPsw transgenic mouse model for Alzheimer's disease. J. Neurosci. Methods 87 : 87 95.
    • (1999) J. Neurosci. Methods , vol.87 , pp. 87-95
    • Pompl, P.N.1    Mullan, M.J.2    Bjugstad, K.3    Arendash, G.W.4
  • 19
    • 0347723879 scopus 로고    scopus 로고
    • The Akt-regulated forkhead transcription factor FoxO3a controls endothelial cell viability through modulation of the caspase-8 inhibitor FLIP
    • Skurk, C., H. Maatz, H.S. Kim, et al. 2004. The Akt-regulated forkhead transcription factor FoxO3a controls endothelial cell viability through modulation of the caspase-8 inhibitor FLIP. J. Biol. Chem. 279 : 1513 1525.
    • (2004) J. Biol. Chem. , vol.279 , pp. 1513-1525
    • Skurk, C.1    Maatz, H.2    Kim, H.S.3
  • 20
    • 12144290563 scopus 로고    scopus 로고
    • Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
    • Brunet, A., L.B. Sweeney, J.F. Sturgill, et al. 2004. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303 : 2011 2015.
    • (2004) Science , vol.303 , pp. 2011-2015
    • Brunet, A.1    Sweeney, L.B.2    Sturgill, J.F.3
  • 21
    • 15744397372 scopus 로고    scopus 로고
    • Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK
    • Pedrini, S., T.L. Carter, G. Prendergast, et al. 2005. Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK. PLoS Med. 2 : e18.
    • (2005) PLoS Med. , vol.2
    • Pedrini, S.1    Carter, T.L.2    Prendergast, G.3
  • 22
    • 0024160877 scopus 로고
    • Role of insulin resistance in human disease. Banting lecture
    • Reaven, G.M. 1988. Role of insulin resistance in human disease. Banting lecture. Diabetes 37 : 1595 15607.
    • (1988) Diabetes , vol.37 , pp. 1595-15607
    • Reaven, G.M.1
  • 24
    • 33748792821 scopus 로고    scopus 로고
    • Opposing activities protect against age-onset proteotoxicity
    • Cohen E, Bieschke J, Perciavalle RM, et al. 2006. Opposing activities protect against age-onset proteotoxicity. Science 313 : 1604 1610.
    • (2006) Science , vol.313 , pp. 1604-1610
    • Cohen, E.1    Bieschke, J.2    Perciavalle, R.M.3
  • 25
    • 0034609737 scopus 로고    scopus 로고
    • Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
    • Dijkers, P.F., R.H. Medema, J.W. Lammers, et al. 2000. Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Curr. Biol. 10 : 1201 1204.
    • (2000) Curr. Biol. , vol.10 , pp. 1201-1204
    • Dijkers, P.F.1    Medema, R.H.2    Lammers, J.W.3
  • 26
    • 33645633087 scopus 로고    scopus 로고
    • Protein phosphatase 2A regulates bim expression via the Akt/FKHRL1 signaling pathway in amyloid-beta peptide-induced cerebrovascular endothelial cell death
    • Yin, K.J., C.Y. Hsu, X.Y. Hu, et al. 2006. Protein phosphatase 2A regulates bim expression via the Akt/FKHRL1 signaling pathway in amyloid-beta peptide-induced cerebrovascular endothelial cell death. J. Neurosci. 26 : 2290 2299.
    • (2006) J. Neurosci. , vol.26 , pp. 2290-2299
    • Yin, K.J.1    Hsu, C.Y.2    Hu, X.Y.3
  • 27
    • 0036850972 scopus 로고    scopus 로고
    • Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons
    • Linseman, D.A., R.A. Phelps, R.J. Bouchard, et al. 2002. Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons. J. Neurosci. 22 : 9287 9297.
    • (2002) J. Neurosci. , vol.22 , pp. 9287-9297
    • Linseman, D.A.1    Phelps, R.A.2    Bouchard, R.J.3
  • 28
    • 33846959101 scopus 로고    scopus 로고
    • Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in Squirrel monkeys (Saimiri sciureus)
    • Qin, W., M. Chachich, M. Lane, et al. 2006b. Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in Squirrel monkeys (Saimiri sciureus). J. Alzheimers Dis. 10 : 417 422.
    • (2006) J. Alzheimers Dis. , vol.10 , pp. 417-422
    • Qin, W.1    Chachich, M.2    Lane, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.