Enaminones 8: CoMFA and CoMSIA studies on some anticonvulsant enaminones

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 1, 2009, Pages 133-140

  Jackson, Patrice L ^a   Scott, K R ^a   Southerland, William M ^a   Fang, Ya Yin ^a  

^a HOWARD UNIVERSITY   (United States)

Author keywords

3D QSAR; CoMFA; CoMSIA; Enaminones; scPTZ

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; ANTICONVULSIVE AGENT; ENAMINONE 8 DERIVATIVE; ENAMINONE DERIVATIVE; PENTETRAZOLE; UNCLASSIFIED DRUG;

ANTICONVULSANT ACTIVITY; ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; COMPUTER PREDICTION; DRUG POTENCY; DRUG SYNTHESIS; ELECTROCHEMICAL DETECTION; MOLECULAR MODEL; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; THREE DIMENSIONAL IMAGING;

ANTICONVULSANTS; BIPHENYL COMPOUNDS; DRUG DESIGN; GABA ANTAGONISTS; HUMANS; IMIDAZOLES; MODELS, MOLECULAR; PENTYLENETETRAZOLE; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, GABA;

EID: 57649150083     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.11.014     Document Type: Article

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