Docking-based 3D-QSAR study for 11β-HSD1 inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 7, 2008, Pages 2479-2490

  Lee, Jin Hee ^a   Kang, Nam Sook ^a   Yoo, Sung Eun ^a  

^a Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

11 HSD1; 3D QSAR; Docking; Inhibitor design

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1 INHIBITOR; ENZYME INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; DRUG ACTIVITY; MOLECULAR DOCKING; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; ALGORITHMS; BINDING SITES; COMPUTER SIMULATION; ENZYME INHIBITORS; LIGANDS; MOLECULAR CONFORMATION; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 41149180681     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.02.042     Document Type: Article

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