Enaminones 9. Further studies on the anticonvulsant activity and potential type IV phosphodiesterase inhibitory activity of substituted vinylic benzamides

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 4, 2006, Pages 997-1006

  Anderson, Alan J ^a,b   Nicholson, Jesse M ^a   Bakare, Oladapo ^a   Butcher, Ray J ^a   Wilson, Tiffany L ^a,c   Scott, K R ^a  

^a HOWARD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

^c ALBANY STATE UNIVERSITY   (United States)

Author keywords

Anticonvulsant evaluation; Base catalyzed parallel synthesis; Benzamides; Enaminones; PDE4 inhibition; QSAR analysis; X ray analysis

Indexed keywords

3 CHLORO N (3 OXOCYCLOHEX 1 ENYL)BENZAMIDE; 3 CHLORO N (5 METHYL 3 OXOCYCLOHEX 1 ENYL)BENZAMIDE; 3 CHLORO N (5,5 DIMETHYL 3 OXOCYCLOHEX 1 ENYL)BENZAMIDE; 3 CYCLOPENTYLOXY 4 METHOXY N (3 OXOCYCLOHEX 1 ENYL)BENZAMIDE; 3 CYCLOPENTYLOXY 4 METHOXY N (5 METHYL 3 OXOCYCLOHEX 1 ENYL)BENZAMIDE; 3 CYCLOPENTYLOXY 4 METHOXY N (5,5 DIMETHYL 3 OXOCYCLOHEX 1 ENYL)BENZAMIDE; 3 N BUTOXY 4 METHOXY N (3 OXOCYCLOHEX 1 ENYL)BENZAMIDE; 3 N BUTOXY 4 METHOXY N (5 METHYL 3 OXOCYCLOHEX 1 ENYL)BENZAMIDE; 3 N BUTOXY 4 METHOXY N (5,5 DIMETHYL 3 OXOCYCLOHEX 1 ENYL)BENZAMIDE; 3,4 DIMETHOXY N (3 OXOCYCLOHEX 1 ENYL)BENZAMIDE; 3,4 DIMETHOXY N (5 METHYL 3 OXOCYCLOHEX 1 ENYL)BENZAMIDE; 3,4 DIMETHOXY N (5,5 DIMETHYL 3 OXOCYCLOHEX 1 ENYL)BENZAMIDE; BENZAMIDE DERIVATIVE; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; MOLECULAR INTERACTION; MOLECULAR MODEL; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; SEIZURE; STRUCTURE ACTIVITY RELATION; X RAY ANALYSIS;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; ANTICONVULSANTS; BENZAMIDES; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; MICE; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; VINYL COMPOUNDS;

ANIMALIA;

EID: 30344438837     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.09.023     Document Type: Article

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