Development of CoMFA, advance CoMFA and CoMSIA models in pyrroloquinazolines as thrombin receptor antagonist

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 13, 2004, Pages 3591-3598

  Dixit, Anshuman ^a   Kashaw, Sushil K ^a   Gaur, Stuti ^a   Saxena, Anil K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

CoMFA; CoMSIA; QSAR; Thrombin receptor antagonist

Indexed keywords

PROTEIN INHIBITOR; QUINAZOLINE DERIVATIVE; THROMBIN RECEPTOR;

ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; DRUG ACTIVITY; MOLECULAR MODEL; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STATISTICAL SIGNIFICANCE;

CATALYSIS; HYDROGEN BONDING; HYDROPHOBICITY; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PYRROLES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; QUINOLINES; RECEPTORS, THROMBIN;

EID: 2942573520     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.04.016     Document Type: Article

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