Asymmetric synthesis and biological evaluation of glycosidic prodrugs for a selective cancer therapy

ChemMedChem

Volumn 3, Issue 12, 2008, Pages 1946-1955

  Tietze, Lutz F ^a   Von Hof, J Marian ^a   Krewer, Birgit ^a   Müller, Michael ^a   Major, Felix ^a   Schuster, Heiko J ^a   Schuberth, Ingrid ^a   Alves, Frauke ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

ADEPT; Antitumor agents; Duocarmycins; Epoxides; Glycosides; Prodrugs

Indexed keywords

ANTINEOPLASTIC AGENT; BETA GALACTOSIDASE; DUOCARMYCIN SA; GLYCOSIDE; INDOLE DERIVATIVE; PRODRUG; PYRROLE DERIVATIVE;

ARTICLE; CHEMISTRY; HUMAN; IC 50; METABOLISM; NEOPLASM; STEREOISOMERISM; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; BETA-GALACTOSIDASE; CELL LINE, TUMOR; GLYCOSIDES; HUMANS; INDOLES; INHIBITORY CONCENTRATION 50; NEOPLASMS; PRODRUGS; PYRROLES; STEREOISOMERISM;

EID: 57549108328     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.200800250     Document Type: Article

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