Age-dependent and tissue-specific CAG repeat instability occurs in mouse knock-in for a mutant Huntington's disease gene

Journal of Neuroscience Research

Volumn 65, Issue 4, 2001, Pages 289-297

  Ishiguro, Hiroshi ^a   Yamada, Kouji ^a   Sawada, Hirohide ^a   Nishii, Kazuhiro ^a   Ichino, Naohiro ^a   Sawada, Makoto ^a   Kurosawa, Yoshikazu ^a   Matsushita, Natsuki ^b   Kobayashi, Kazuto ^b   Goto, Jun ^c   Hashida, Hideji ^c   Masuda, Naoki ^c   Kanazawa, Ichiro ^c   Nagatsu, Toshiharu ^a  

^a FUJITA HEALTH UNIVERSITY   (Japan)

^b FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Astrogliosis; CAG repeat instability; Huntington's disease; Knock in mouse

Indexed keywords

DNA; GLIAL FIBRILLARY ACIDIC PROTEIN; MUTANT PROTEIN;

AGED; AGING; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; CONTROLLED STUDY; DEGENERATIVE DISEASE; GENE MUTATION; GLOBUS PALLIDUS; HUNTINGTON CHOREA; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SUBSTANTIA NIGRA; TISSUE SPECIFICITY; TRINUCLEOTIDE REPEAT;

AGE FACTORS; ANIMALS; ASTROCYTES; DISEASE MODELS, ANIMAL; EXONS; GENE EXPRESSION; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOSIS; GLOBUS PALLIDUS; HUMANS; HUNTINGTON DISEASE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; MOSAICISM; NEOSTRIATUM; SUBSTANTIA NIGRA; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 0035882460     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.1153     Document Type: Article

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