Uncoupling of longevity and paraquat resistance in mutants of the nematode Caenorhabditis elegans

Bioscience, Biotechnology and Biochemistry

Volumn 69, Issue 10, 2005, Pages 2015-2018

  Fujii, Michihiko ^a   Tanaka, Nanae ^a   Miki, Kensuke ^a   Hossain, Mohammad Nazir ^a   Endoh, Morio ^a   Ayusawa, Dai ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Aging; Caenorhabditis elegans; Dyf; Oxidative stress; Paraquat

Indexed keywords

CELLS; ELECTRIC RESISTANCE; OXIDATION; THERMAL EFFECTS; ULTRAVIOLET RADIATION;

AGING; CAENORHABDITIS ELEGANS; DYF; OXIDATIVE STRESS; PARAQUAT;

MUTAGENESIS;

PARAQUAT;

AGING; ANIMAL; ANIMAL MODEL; ARTICLE; CAENORHABDITIS ELEGANS; DRUG EFFECT; DRUG RESISTANCE; GENETICS; LONGEVITY; OXIDATIVE STRESS; PHYSIOLOGY;

AGING; ANIMALS; CAENORHABDITIS ELEGANS; DRUG RESISTANCE; LONGEVITY; MODELS, ANIMAL; OXIDATIVE STRESS; PARAQUAT;

CAENORHABDITIS ELEGANS;

EID: 27644461297     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.69.2015     Document Type: Article

References (18)

1. Harman, D., Aging: a theory based on free radical and radiation chemistry. J. Gerontol., 2, 293-300 (1957).
2. Finkel, T., and Holbrook, N. J., Oxidants, oxidative stress and the biology of ageing. Nature, 408, 239-247 (2000).
3. Martin, G. M., Austad, S. N., and Johnson, T. E., Genetic analysis of ageing: role of oxidative damage and environmental stresses. Nat. Genet., 13, 25-34 (1996).
4. Ishii, N., Takahashi, K., Tomita, S., Keino, T., Honda, S., Yoshino, K., and Suzuki, K., A methyl viologen-sensitive mutant of the nematode Caenorhabditis elegans. Mutat. Res., 237, 165-171 (1990).
5. Fujii, M., Matsumoto, Y., Tanaka, N., Miki, K., Suzuki, T., Ishii, N., and Ayusawa, D., Mutations in chemosensory cilia cause resistance to paraquat in nematode Caenorhabditis elegans. J. Biol. Chem., 279, 20277-20282 (2004).
6. Murakami, S., and Johnson, T. E., Life extension and stress resistance in Caenorhabditis elegans modulated by the tkr-1 gene. Curr. Biol., 8, 1091-1094 (1998).
7. Murakami, S., and Johnson, T. E., A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans. Genetics, 143, 1207-1218 (1996).
8. Lithgow, G. J., White, T. M., Melov, S., and Johnson, T. E., Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress. Proc. Natl. Acad. Sci. U.S.A., 92, 7540-7544 (1995).
9. Perkins, L. A., Hedgecock, E. M., Thomson, J. N., and Culotti, J. G., Mutant sensory cilia in the nematode Caenorhabditis elegans. Dev. Biol., 117, 456-487 (1986).
10. Parkes, T. L., Elia, A. J., Dickinson, D., Hilliker, A. J., Phillips, J. P., and Boulianne, G. L., Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons. Nat. Genet., 19, 171-174 (1998).
11. Munoz, M. J., and Riddle, D. L., Positive selection of Caenorhabditis elegans mutants with increased stress resistance and longevity. Genetics, 163, 171-180 (2003).
12. Lin, K., Dorman, J. B., Rodan, A., and Kenyon, C., daf-16: an HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science, 278, 1319-1322 (1997).
13. Ogg, S., Paradis, S., Gottlieb, S., Patterson, G. I., Lee, L., Tissenbaum, H. A., and Ruvkun, G., The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature, 389, 994-999 (1997).
14. Lee, S. S., Kennedy, S., Tolonen, A. C., and Ruvkun, G., DAF-16 target genes that control C. elegans life-span and metabolism. Science, 300, 644-647 (2003).
15. Murphy, C. T., McCarroll, S. A., Bargmann, C. I., Fraser, A., Kamath, R. S., Ahringer, J., Li, H., and Kenyon, C., Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature, 424, 277-283 (2003).
16. Apfeld, J., and Kenyon, C., Regulation of lifespan by sensory perception in Caenorhabditis elegans. Nature, 402, 804-809 (1999).
17. Lin, K., Hsin, H., Libina, N., and Kenyon, C., Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nat. Genet., 28, 139-145 (2001).
18. Hedgecock, E. M., Culotti, J. G., Thomson, J. N., and Perkins, L. A., Axonal guidance mutants of Caenorhabditis elegans identified by filling sensory neurons with fluorescein dyes. Dev. Biol., 111, 158-170 (1985).