메뉴 건너뛰기




Volumn 7, Issue 10, 2008, Pages 1507-1517

Emerging applications of anticytokine vaccines

Author keywords

Cytokine; Immunotherapy; Inflammatory disease; Monoclonal antibody; Vaccination

Indexed keywords

AUTOANTIBODY; CD4 ANTIGEN; CYTOKINE; CYTOKINE RECEPTOR; DENOSUMAB; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 27; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 9; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCLONAL ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 1; NAKED DNA; NEUTRALIZING ANTIBODY; OSTEOCLAST DIFFERENTIATION FACTOR; PLASMID DNA; RANTES; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG; VACCINE;

EID: 57349190608     PISSN: 14760584     EISSN: 17448395     Source Type: Journal    
DOI: 10.1586/14760584.7.10.1507     Document Type: Review
Times cited : (11)

References (72)
  • 1
    • 0016046244 scopus 로고
    • Commentary. Similarities of T cell function in cell-mediated immunity and antibody production
    • Cohen S, Bigazzi PE, Yoshida T. Commentary. Similarities of T cell function in cell-mediated immunity and antibody production. Cell. Immunol. 12(1), 150-159 (1974).
    • (1974) Cell. Immunol , vol.12 , Issue.1 , pp. 150-159
    • Cohen, S.1    Bigazzi, P.E.2    Yoshida, T.3
  • 2
    • 57349152781 scopus 로고    scopus 로고
    • Introduction to the role of cytokines in innate host defense and adaptive immunity
    • Eds, Academic Press, London, UK 3-20
    • Oppenheim JJ, Feldmann M. Introduction to the role of cytokines in innate host defense and adaptive immunity. In: Cytokine Reference, Volume 1: Ligands. Oppenheim JJ, Feldmann M (Eds). Academic Press, London, UK 3-20 (2000).
    • (2000) Cytokine Reference, Volume 1: Ligands
    • Oppenheim, J.J.1    Feldmann, M.2
  • 3
    • 0033645975 scopus 로고    scopus 로고
    • Reflections on chemokines
    • Baggiolini M. Reflections on chemokines. Immunol. Rev. 177, 5-7 (2000).
    • (2000) Immunol. Rev , vol.177 , pp. 5-7
    • Baggiolini, M.1
  • 4
    • 0142181040 scopus 로고    scopus 로고
    • Autoimmune aspects of cytokine and anticytokine therapies
    • Krause I, Valesini G, Scrivo R, Shoenfeld Y. Autoimmune aspects of cytokine and anticytokine therapies. Am. J. Med. 115(5), 390-397 (2003).
    • (2003) Am. J. Med , vol.115 , Issue.5 , pp. 390-397
    • Krause, I.1    Valesini, G.2    Scrivo, R.3    Shoenfeld, Y.4
  • 5
    • 0024815233 scopus 로고
    • A humanized antibody that binds to the interleukin 2 receptor
    • Queen C, Schneider WP, Selick HE et al. A humanized antibody that binds to the interleukin 2 receptor. Proc. Natl Acad. Sci. USA 86(24), 10029-10033 (1989).
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , Issue.24 , pp. 10029-10033
    • Queen, C.1    Schneider, W.P.2    Selick, H.E.3
  • 6
    • 16644362629 scopus 로고    scopus 로고
    • Monoclonal antibody-based strategies in autoimmunity and transplantation
    • Chatenoud L. Monoclonal antibody-based strategies in autoimmunity and transplantation. Methods Mol. Med. 109, 297-328 (2005).
    • (2005) Methods Mol. Med , vol.109 , pp. 297-328
    • Chatenoud, L.1
  • 7
    • 0037379605 scopus 로고    scopus 로고
    • Active versus passive anticytokine antibody therapy against cytokine-associated chronic diseases
    • Zagury D, Le Buanec H, Bizzini B, Burny A, Lewis G, Gallo RC. Active versus passive anticytokine antibody therapy against cytokine-associated chronic diseases. Cytokine Growth Factor Rev. 14(2), 123-137 (2003).
    • (2003) Cytokine Growth Factor Rev , vol.14 , Issue.2 , pp. 123-137
    • Zagury, D.1    Le Buanec, H.2    Bizzini, B.3    Burny, A.4    Lewis, G.5    Gallo, R.C.6
  • 8
    • 34247590217 scopus 로고    scopus 로고
    • Anticytokine autoantibodies are ubiquitous in healthy individuals
    • Watanabe M, Uchida K, Nakagaki K et al. Anticytokine autoantibodies are ubiquitous in healthy individuals. FEBS Lett. 581(10), 2017-2021 (2007).
    • (2007) FEBS Lett , vol.581 , Issue.10 , pp. 2017-2021
    • Watanabe, M.1    Uchida, K.2    Nakagaki, K.3
  • 9
    • 0347135823 scopus 로고    scopus 로고
    • Therapeutic vaccination for chronic diseases: A new class of drugs in sight
    • Bachmann MF, Dyer MR. Therapeutic vaccination for chronic diseases: a new class of drugs in sight. Nat. Rev. Drug Discov. 3(1), 81-88 (2004).
    • (2004) Nat. Rev. Drug Discov , vol.3 , Issue.1 , pp. 81-88
    • Bachmann, M.F.1    Dyer, M.R.2
  • 10
    • 40049106627 scopus 로고    scopus 로고
    • Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: A double-blind, randomised, placebo-controlled Phase IIa study
    • Tissot AC, Maurer P, Nussberger J et al. Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: a double-blind, randomised, placebo-controlled Phase IIa study. Lancet 371(9615), 821-827 (2008).
    • (2008) Lancet , vol.371 , Issue.9615 , pp. 821-827
    • Tissot, A.C.1    Maurer, P.2    Nussberger, J.3
  • 11
    • 44949133037 scopus 로고    scopus 로고
    • Vaccination with cytokines in autoimmune diseases
    • Delavallee L, Assier E, Denys A et al. Vaccination with cytokines in autoimmune diseases. Ann. Med. 40(5), 343-351 (2008).
    • (2008) Ann. Med , vol.40 , Issue.5 , pp. 343-351
    • Delavallee, L.1    Assier, E.2    Denys, A.3
  • 12
    • 0033018740 scopus 로고    scopus 로고
    • Therapeutic antibodies elicited by immunization against TNF-α
    • Dalum I, Butler DM, Jensen MR et al. Therapeutic antibodies elicited by immunization against TNF-α. Nat. Biotechnol. 17(7), 666-669 (1999).
    • (1999) Nat. Biotechnol , vol.17 , Issue.7 , pp. 666-669
    • Dalum, I.1    Butler, D.M.2    Jensen, M.R.3
  • 13
    • 34848850384 scopus 로고    scopus 로고
    • Active immunotherapy of allergic asthma with a recombinant human interleukin-5 protein as vaccine in a murine model
    • Tan GH, Wang CC, Huang FY, Wang H, Huang YH, Lin YY. Active immunotherapy of allergic asthma with a recombinant human interleukin-5 protein as vaccine in a murine model. Chin. Med. J. (Engl.) 120(17), 1517-1522 (2007).
    • (2007) Chin. Med. J. (Engl.) , vol.120 , Issue.17 , pp. 1517-1522
    • Tan, G.H.1    Wang, C.C.2    Huang, F.Y.3    Wang, H.4    Huang, Y.H.5    Lin, Y.Y.6
  • 14
    • 33751254750 scopus 로고    scopus 로고
    • Vaccination against IL-17 suppresses autoimmune arthritis and encephalomyelitis
    • Efficiency of a vaccine in two experimental autoimmune inflammatory diseases, •
    • Rohn TA, Jennings GT, Hernandez M et al. Vaccination against IL-17 suppresses autoimmune arthritis and encephalomyelitis. Eur. J. Immunol. 36(11), 2857-2867 (2006). • Efficiency of a vaccine in two experimental autoimmune inflammatory diseases.
    • (2006) Eur. J. Immunol , vol.36 , Issue.11 , pp. 2857-2867
    • Rohn, T.A.1    Jennings, G.T.2    Hernandez, M.3
  • 15
    • 50249187809 scopus 로고    scopus 로고
    • Early and long-lasting protection from arthritis in tumour necrosis factor α (TNFα) transgenic mice vaccinated against TNFα
    • Detailed description of long-term efficacy of a vaccine and demonstration of reversibility of blockade, ••
    • Delavallee L, Le Buanec H, Bessis N et al. Early and long-lasting protection from arthritis in tumour necrosis factor α (TNFα) transgenic mice vaccinated against TNFα. Ann. Rheum. Dis. 67(9), 1332-1338 (2008). •• Detailed description of long-term efficacy of a vaccine and demonstration of reversibility of blockade.
    • (2008) Ann. Rheum. Dis , vol.67 , Issue.9 , pp. 1332-1338
    • Delavallee, L.1    Le Buanec, H.2    Bessis, N.3
  • 16
    • 34748893102 scopus 로고    scopus 로고
    • Control of allergic reactions in mice by an active anti-murine IL-4 immunization
    • Le Buanec H, Paturance S, Couillin I et al. Control of allergic reactions in mice by an active anti-murine IL-4 immunization. Vaccine 25(41), 7206-7216 (2007).
    • (2007) Vaccine , vol.25 , Issue.41 , pp. 7206-7216
    • Le Buanec, H.1    Paturance, S.2    Couillin, I.3
  • 17
    • 33751243318 scopus 로고    scopus 로고
    • Development of an anti-IL-17A auto-vaccine that prevents experimental auto-immune encephalomyelitis
    • Uyttenhove C, Van Snick J. Development of an anti-IL-17A auto-vaccine that prevents experimental auto-immune encephalomyelitis. Eur. J. Immunol. 36(11), 2868-2874 (2006).
    • (2006) Eur. J. Immunol , vol.36 , Issue.11 , pp. 2868-2874
    • Uyttenhove, C.1    Van Snick, J.2
  • 18
    • 10944221275 scopus 로고    scopus 로고
    • Development of an anti-IL-12 p40 auto-vaccine: Protection in experimental autoimmune encephalomyelitis at the expense of increased sensitivity to infection
    • Uyttenhove C, Arendse B, Stroobant V, Brombacher F, Van Snick J. Development of an anti-IL-12 p40 auto-vaccine: protection in experimental autoimmune encephalomyelitis at the expense of increased sensitivity to infection. Eur. J. Immunol. 34(12), 3572-3581 (2004).
    • (2004) Eur. J. Immunol , vol.34 , Issue.12 , pp. 3572-3581
    • Uyttenhove, C.1    Arendse, B.2    Stroobant, V.3    Brombacher, F.4    Van Snick, J.5
  • 19
    • 0031908427 scopus 로고    scopus 로고
    • Gene vaccination: Plasmid DNA is more than just a blueprint
    • Tighe H, Corr M, Roman M, Raz E. Gene vaccination: plasmid DNA is more than just a blueprint. Immunol. Today 19(2), 89-97 (1998).
    • (1998) Immunol. Today , vol.19 , Issue.2 , pp. 89-97
    • Tighe, H.1    Corr, M.2    Roman, M.3    Raz, E.4
  • 20
    • 34447283518 scopus 로고    scopus 로고
    • Human TNF-α gene vaccination prevents collagen-induced arthritis in mice
    • Shen Y, Chen J, Zhang X, Wu X, Xu Q. Human TNF-α gene vaccination prevents collagen-induced arthritis in mice. Int. Immunopharmacol. 7(9), 1140-1149 (2007).
    • (2007) Int. Immunopharmacol , vol.7 , Issue.9 , pp. 1140-1149
    • Shen, Y.1    Chen, J.2    Zhang, X.3    Wu, X.4    Xu, Q.5
  • 21
    • 0032532308 scopus 로고    scopus 로고
    • Long-lasting protective immunity to experimental autoimmune encephalomyelitis following vaccination with naked DNA encoding C-C chemokines
    • Youssef S, Wildbaum G, Maor G et al. Long-lasting protective immunity to experimental autoimmune encephalomyelitis following vaccination with naked DNA encoding C-C chemokines. J. Immunol. 161(8), 3870-3879 (1998).
    • (1998) J. Immunol , vol.161 , Issue.8 , pp. 3870-3879
    • Youssef, S.1    Wildbaum, G.2    Maor, G.3
  • 22
    • 14244268426 scopus 로고    scopus 로고
    • Antigen epitope-expressing cytokines for DNA immunization
    • He X, Tsang TC, Zhang T, Luo P, Harris DT. Antigen epitope-expressing cytokines for DNA immunization. Vaccine 23(16), 1966-1972 (2005).
    • (2005) Vaccine , vol.23 , Issue.16 , pp. 1966-1972
    • He, X.1    Tsang, T.C.2    Zhang, T.3    Luo, P.4    Harris, D.T.5
  • 23
    • 37048999583 scopus 로고    scopus 로고
    • TNFα antagonists in rheumatoid arthritis patients seen in everyday practice
    • Falgarone G, Duclos M, Boissier MC. TNFα antagonists in rheumatoid arthritis patients seen in everyday practice. Joint Bone Spine 74(6), 523-526 (2007).
    • (2007) Joint Bone Spine , vol.74 , Issue.6 , pp. 523-526
    • Falgarone, G.1    Duclos, M.2    Boissier, M.C.3
  • 24
    • 46749125294 scopus 로고    scopus 로고
    • Shifting the imbalance from Th1/Th2 to Th17/treg: The changing rheumatoid arthritis paradigm
    • Boissier MC, Assier E, Falgarone G, Bessis N. Shifting the imbalance from Th1/Th2 to Th17/treg: the changing rheumatoid arthritis paradigm. Joint Bone Spine 74(4), 373-375 (2008).
    • (2008) Joint Bone Spine , vol.74 , Issue.4 , pp. 373-375
    • Boissier, M.C.1    Assier, E.2    Falgarone, G.3    Bessis, N.4
  • 25
    • 0026039673 scopus 로고
    • Transgenic mice expressing human tumour necrosis factor: A predictive genetic model of arthritis
    • Keffer J, Probert L, Cazlaris H et al. Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. EMBO J. 10(13), 4025-4031 (1991).
    • (1991) EMBO J , vol.10 , Issue.13 , pp. 4025-4031
    • Keffer, J.1    Probert, L.2    Cazlaris, H.3
  • 26
    • 36148986078 scopus 로고    scopus 로고
    • Intra-articular electrotransfer of plasmid encoding soluble TNF receptor variants in normal and arthritic mice
    • Bloquel C, Denys A, Boissier MC et al. Intra-articular electrotransfer of plasmid encoding soluble TNF receptor variants in normal and arthritic mice. J. Gene Med. 9(11), 986-993 (2007).
    • (2007) J. Gene Med , vol.9 , Issue.11 , pp. 986-993
    • Bloquel, C.1    Denys, A.2    Boissier, M.C.3
  • 27
    • 0034669914 scopus 로고    scopus 로고
    • A targeted DNA vaccine augments the natural immune response to self TNF-α and suppresses ongoing adjuvant arthritis
    • Wildbaum G, Youssef S, Karin N. A targeted DNA vaccine augments the natural immune response to self TNF-α and suppresses ongoing adjuvant arthritis. J. Immunol. 165(10), 5860-5866 (2000).
    • (2000) J. Immunol , vol.165 , Issue.10 , pp. 5860-5866
    • Wildbaum, G.1    Youssef, S.2    Karin, N.3
  • 28
    • 0034898470 scopus 로고    scopus 로고
    • Conjugation of a self-antigen to papillomavirus-like particles allows for efficient induction of protective autoantibodies
    • Chackerian B, Lowy DR, Schiller JT. Conjugation of a self-antigen to papillomavirus-like particles allows for efficient induction of protective autoantibodies. J. Clin. Invest. 108(3), 415-423 (2001).
    • (2001) J. Clin. Invest , vol.108 , Issue.3 , pp. 415-423
    • Chackerian, B.1    Lowy, D.R.2    Schiller, J.T.3
  • 29
    • 34249809700 scopus 로고    scopus 로고
    • A virus-like particle-based vaccine selectively targeting soluble TNF-α protects from arthritis without inducing reactivation of latent tuberculosis
    • Vaccine against TNF designed with virus-like particles VLPs, •
    • Spohn G, Guler R, Johansen P et al. A virus-like particle-based vaccine selectively targeting soluble TNF-α protects from arthritis without inducing reactivation of latent tuberculosis. J. Immunol. 178(11), 7450-7457 (2007). • Vaccine against TNF designed with virus-like particles (VLPs).
    • (2007) J. Immunol , vol.178 , Issue.11 , pp. 7450-7457
    • Spohn, G.1    Guler, R.2    Johansen, P.3
  • 30
    • 0029300707 scopus 로고
    • Kinoids: The basis for anticytokine immunization and their use in HIV infection
    • Bizzini B, Achour A. "Kinoids": the basis for anticytokine immunization and their use in HIV infection. Cell. Mol. Biol. (Noisy-le-Grand) 41(3), 351-356 (1995).
    • (1995) Cell. Mol. Biol. (Noisy-le-Grand) , vol.41 , Issue.3 , pp. 351-356
    • Bizzini, B.1    Achour, A.2
  • 31
    • 33845879373 scopus 로고    scopus 로고
    • Le Buanec H, Delavallee L, Bessis N et al. TNFα kinoid vaccination-induced neutralizing antibodies to TNFα protect mice from autologous TNFα-driven chronic and acute inflammation. Proc. Natl Acad. Sci. USA, 103(51), 19442-19447 (2006). •• Seminal description of the efficacy of a vaccine against TNF in acute and chronic models of inflammation.
    • Le Buanec H, Delavallee L, Bessis N et al. TNFα kinoid vaccination-induced neutralizing antibodies to TNFα protect mice from autologous TNFα-driven chronic and acute inflammation. Proc. Natl Acad. Sci. USA, 103(51), 19442-19447 (2006). •• Seminal description of the efficacy of a vaccine against TNF in acute and chronic models of inflammation.
  • 32
    • 43649107676 scopus 로고    scopus 로고
    • Active immunization with IL-1 displayed on virus-like particles protects from autoimmune arthritis
    • Spohn G, Keller I, Beck M, Grest P, Jennings GT, Bachmann MF. Active immunization with IL-1 displayed on virus-like particles protects from autoimmune arthritis. Eur. J. Immunol. 38(3), 877-887 (2008).
    • (2008) Eur. J. Immunol , vol.38 , Issue.3 , pp. 877-887
    • Spohn, G.1    Keller, I.2    Beck, M.3    Grest, P.4    Jennings, G.T.5    Bachmann, M.F.6
  • 33
    • 22144457874 scopus 로고    scopus 로고
    • Improvement of collagen-induced arthritis by active immunization against murine IL-1β peptides designed by molecular modelling, • Report on a vaccine against a cytokine peptide
    • Bertin-Maghit SM, Capini CJ et al. Improvement of collagen-induced arthritis by active immunization against murine IL-1β peptides designed by molecular modelling. Vaccine 23(33), 4228-4235 (2005). • Report on a vaccine against a cytokine peptide.
    • (2005) Vaccine , vol.23 , Issue.33 , pp. 4228-4235
    • Bertin-Maghit, S.M.1    Capini, C.J.2
  • 34
    • 13444256307 scopus 로고    scopus 로고
    • The role of T-cell interleukin-17 in conducting destructive arthritis: Lessons from animal models
    • Lubberts E, Koenders MI, van den Berg WB. The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models. Arthritis Res. Ther. 7(1), 29-37 (2005).
    • (2005) Arthritis Res. Ther , vol.7 , Issue.1 , pp. 29-37
    • Lubberts, E.1    Koenders, M.I.2    van den Berg, W.B.3
  • 35
    • 35748943527 scopus 로고    scopus 로고
    • Vaccination with IL-6 analogues induces autoantibodies to IL-6 and influences experimentally induced inflammation
    • Galle P, Jensen L, Andersson C et al. Vaccination with IL-6 analogues induces autoantibodies to IL-6 and influences experimentally induced inflammation. Int. Immunopharmacol. 7(13), 1704-1713 (2007).
    • (2007) Int. Immunopharmacol , vol.7 , Issue.13 , pp. 1704-1713
    • Galle, P.1    Jensen, L.2    Andersson, C.3
  • 36
    • 33847084328 scopus 로고    scopus 로고
    • Onodera S, Ohshima S, Tohyama H et al. A novel DNA vaccine targeting macrophage migration inhibitory factor protects joints from inflammation and destruction in murine models of arthritis. Arthritis Rheum. 56(2), 521-530 (2007). •• DNA vaccine targeted to the site of inflammation.
    • Onodera S, Ohshima S, Tohyama H et al. A novel DNA vaccine targeting macrophage migration inhibitory factor protects joints from inflammation and destruction in murine models of arthritis. Arthritis Rheum. 56(2), 521-530 (2007). •• DNA vaccine targeted to the site of inflammation.
  • 37
    • 3142719733 scopus 로고    scopus 로고
    • Suppression of ongoing adjuvant-induced arthritis by neutralizing the function of the p28 subunit of IL-27
    • Goldberg R, Wildbaum G, Zohar Y, Maor G, Karin N. Suppression of ongoing adjuvant-induced arthritis by neutralizing the function of the p28 subunit of IL-27. J. Immunol. 173(2), 1171-1178 (2004).
    • (2004) J. Immunol , vol.173 , Issue.2 , pp. 1171-1178
    • Goldberg, R.1    Wildbaum, G.2    Zohar, Y.3    Maor, G.4    Karin, N.5
  • 38
    • 0032525890 scopus 로고    scopus 로고
    • Polyclonal antibody directed against human RANTES ameliorates disease in the Lewis rat adjuvant-induced arthritis model
    • Barnes DA, Tse J, Kaufhold M et al. Polyclonal antibody directed against human RANTES ameliorates disease in the Lewis rat adjuvant-induced arthritis model. J. Clin. Invest. 101(12), 2910-2919 (1998).
    • (1998) J. Clin. Invest , vol.101 , Issue.12 , pp. 2910-2919
    • Barnes, D.A.1    Tse, J.2    Kaufhold, M.3
  • 39
    • 0033846366 scopus 로고    scopus 로고
    • C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis
    • Youssef S, Maor G, Wildbaum G, Grabie N, Gour-Lavie A, Karin N. C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis. J. Clin. Invest. 106(3), 361-371 (2000).
    • (2000) J. Clin. Invest , vol.106 , Issue.3 , pp. 361-371
    • Youssef, S.1    Maor, G.2    Wildbaum, G.3    Grabie, N.4    Gour-Lavie, A.5    Karin, N.6
  • 40
    • 8444235333 scopus 로고    scopus 로고
    • Suppression of ongoing experimental autoimmune encephalomyelitis by neutralizing the function of the p28 subunit of IL-27
    • Goldberg R, Zohar Y, Wildbaum G, Geron Y, Maor G, Karin N. Suppression of ongoing experimental autoimmune encephalomyelitis by neutralizing the function of the p28 subunit of IL-27. J. Immunol. 173(10), 6465-6471 (2004).
    • (2004) J. Immunol , vol.173 , Issue.10 , pp. 6465-6471
    • Goldberg, R.1    Zohar, Y.2    Wildbaum, G.3    Geron, Y.4    Maor, G.5    Karin, N.6
  • 41
    • 0033058502 scopus 로고    scopus 로고
    • Augmentation of natural immunity to a pro-inflammatory cytokine (TNF-α) by targeted DNA vaccine confers long-lasting resistance to experimental autoimmune encephalomyelitis
    • Wildbaum G, Karin N. Augmentation of natural immunity to a pro-inflammatory cytokine (TNF-α) by targeted DNA vaccine confers long-lasting resistance to experimental autoimmune encephalomyelitis. Gene Ther. 6(6), 1128-1138 (1999).
    • (1999) Gene Ther , vol.6 , Issue.6 , pp. 1128-1138
    • Wildbaum, G.1    Karin, N.2
  • 42
    • 0028803845 scopus 로고
    • An important role for the chemokine macrophage inflammatory protein-1 α in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis
    • Karpus WJ, Lukacs NW, McRae BL, Strieter RM, Kunkel SL, Miller SD. An important role for the chemokine macrophage inflammatory protein-1 α in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis. J. Immunol. 155(10), 5003-5010 (1995).
    • (1995) J. Immunol , vol.155 , Issue.10 , pp. 5003-5010
    • Karpus, W.J.1    Lukacs, N.W.2    McRae, B.L.3    Strieter, R.M.4    Kunkel, S.L.5    Miller, S.D.6
  • 43
    • 0032794139 scopus 로고    scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by MIP-1α and MCP-1 naked DNA vaccines
    • Youssef S, Wildbaum G, Karin N. Prevention of experimental autoimmune encephalomyelitis by MIP-1α and MCP-1 naked DNA vaccines. J. Autoimmun. 13(1), 21-29 (1999).
    • (1999) J. Autoimmun , vol.13 , Issue.1 , pp. 21-29
    • Youssef, S.1    Wildbaum, G.2    Karin, N.3
  • 44
    • 0027945732 scopus 로고
    • Depletion of interleukin-4 in BALB/c mice with established Leishmania major infections increases the efficacy of antimony therapy and promotes Th1-like responses
    • Nabors GS, Farrell JP. Depletion of interleukin-4 in BALB/c mice with established Leishmania major infections increases the efficacy of antimony therapy and promotes Th1-like responses. Infect. Immun. 62(12), 5498-5504 (1994).
    • (1994) Infect. Immun , vol.62 , Issue.12 , pp. 5498-5504
    • Nabors, G.S.1    Farrell, J.P.2
  • 45
    • 20144372895 scopus 로고    scopus 로고
    • Therapeutic dosing with anti-interleukin-13 monoclonal antibody inhibits asthma progression in mice
    • Yang G, Li L, Volk A et al. Therapeutic dosing with anti-interleukin-13 monoclonal antibody inhibits asthma progression in mice. J. Pharmacol. Exp. Ther. 313(1), 8-15 (2005).
    • (2005) J. Pharmacol. Exp. Ther , vol.313 , Issue.1 , pp. 8-15
    • Yang, G.1    Li, L.2    Volk, A.3
  • 46
    • 0030928063 scopus 로고    scopus 로고
    • Depletion of eosinophil infiltration by anti-IL-5 monoclonal antibody (TRFK-5) accelerates open skin wound epithelial closure
    • Yang J, Torio A, Donoff RB et al. Depletion of eosinophil infiltration by anti-IL-5 monoclonal antibody (TRFK-5) accelerates open skin wound epithelial closure. Am. J. Pathol. 151(3), 813-819 (1997).
    • (1997) Am. J. Pathol , vol.151 , Issue.3 , pp. 813-819
    • Yang, J.1    Torio, A.2    Donoff, R.B.3
  • 47
    • 0035478849 scopus 로고    scopus 로고
    • Active vaccination against IL-5 bypasses immunological tolerance and ameliorates experimental asthma
    • Hertz M, Mahalingam S, Dalum I et al. Active vaccination against IL-5 bypasses immunological tolerance and ameliorates experimental asthma. J. Immunol. 167(7), 3792-3799 (2001).
    • (2001) J. Immunol , vol.167 , Issue.7 , pp. 3792-3799
    • Hertz, M.1    Mahalingam, S.2    Dalum, I.3
  • 48
    • 40949128356 scopus 로고    scopus 로고
    • A recombinant DNA plasmid encoding the human interleukin-5 breaks immunological tolerance and inhibits airway inflammation in a murine model of asthma
    • Tan GH, Su JM, Wang CC et al. A recombinant DNA plasmid encoding the human interleukin-5 breaks immunological tolerance and inhibits airway inflammation in a murine model of asthma. Int. Arch. Allergy Immunol. 145(4), 313-323 (2008).
    • (2008) Int. Arch. Allergy Immunol , vol.145 , Issue.4 , pp. 313-323
    • Tan, G.H.1    Su, J.M.2    Wang, C.C.3
  • 49
    • 1542316856 scopus 로고    scopus 로고
    • Induction of TNF-α autoantibody production by AutoVac TNF106: A novel therapeutic approach for the treatment of allergic diseases
    • Zuany-Amorim C, Manlius C, Dalum I et al. Induction of TNF-α autoantibody production by AutoVac TNF106: a novel therapeutic approach for the treatment of allergic diseases. Int. Arch. Allergy Immunol. 133(2), 154-163 (2004).
    • (2004) Int. Arch. Allergy Immunol , vol.133 , Issue.2 , pp. 154-163
    • Zuany-Amorim, C.1    Manlius, C.2    Dalum, I.3
  • 50
    • 35448939297 scopus 로고    scopus 로고
    • A potential immunotherapy approach: Mucosal immunization with an IL-13 peptide-based virus-like particle vaccine in a mouse asthma model
    • Ma Y, Ma AG, Peng Z. A potential immunotherapy approach: mucosal immunization with an IL-13 peptide-based virus-like particle vaccine in a mouse asthma model. Vaccine 25(47), 8091-8099 (2007).
    • (2007) Vaccine , vol.25 , Issue.47 , pp. 8091-8099
    • Ma, Y.1    Ma, A.G.2    Peng, Z.3
  • 51
    • 10744222448 scopus 로고    scopus 로고
    • IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease
    • Bossu P, Neumann D, Del Giudice E et al. IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease. Proc. Natl Acad. Sci. USA 100(24), 14181-14186 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , Issue.24 , pp. 14181-14186
    • Bossu, P.1    Neumann, D.2    Del Giudice, E.3
  • 52
    • 23844502618 scopus 로고    scopus 로고
    • Blockade of interleukin-12 function by protein vaccination attenuates atherosclerosis
    • Hauer AD, Uyttenhove C, de Vos P et al. Blockade of interleukin-12 function by protein vaccination attenuates atherosclerosis. Circulation 112(7), 1054-1062 (2005).
    • (2005) Circulation , vol.112 , Issue.7 , pp. 1054-1062
    • Hauer, A.D.1    Uyttenhove, C.2    de Vos, P.3
  • 53
    • 33751242743 scopus 로고    scopus 로고
    • Neutralization of IL-17 by active vaccination inhibits IL-23-dependent autoimmune myocarditis
    • Sonderegger I, Rohn TA, Kurrer MO et al. Neutralization of IL-17 by active vaccination inhibits IL-23-dependent autoimmune myocarditis. Eur. J. Immunol. 36(11), 2849-2856 (2006).
    • (2006) Eur. J. Immunol , vol.36 , Issue.11 , pp. 2849-2856
    • Sonderegger, I.1    Rohn, T.A.2    Kurrer, M.O.3
  • 54
    • 42749092176 scopus 로고    scopus 로고
    • Clinical potential of RANKL Inhibition for the management of postmenopausal osteoporosis and other metabolic bone diseases
    • Delmas PD. Clinical potential of RANKL Inhibition for the management of postmenopausal osteoporosis and other metabolic bone diseases. J. Clin. Densitom. 11(2), 325-338 (2008).
    • (2008) J. Clin. Densitom , vol.11 , Issue.2 , pp. 325-338
    • Delmas, P.D.1
  • 55
    • 27144468615 scopus 로고    scopus 로고
    • Protection against osteoporosis by active immunization with TRANCE/RANKL displayed on virus-like particles
    • Clear-cut effects of a VLP-designed vaccine in a model of osteoporosis, •
    • Spohn G, Schwarz K, Maurer P, Illges H et al. Protection against osteoporosis by active immunization with TRANCE/RANKL displayed on virus-like particles. J. Immunol. 175(9), 6211-6218 (2005). • Clear-cut effects of a VLP-designed vaccine in a model of osteoporosis.
    • (2005) J. Immunol , vol.175 , Issue.9 , pp. 6211-6218
    • Spohn, G.1    Schwarz, K.2    Maurer, P.3    Illges, H.4
  • 56
    • 0034681145 scopus 로고    scopus 로고
    • Anti-IL-9 vaccination prevents worm expulsion and blood eosinophilia in Trichuris muris-infected mice
    • Richard M, Grencis RK, Humphreys NE, Renauld JC, Van Snick J. Anti-IL-9 vaccination prevents worm expulsion and blood eosinophilia in Trichuris muris-infected mice. Proc. Natl Acad. Sci. USA 97(2), 767-772 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , Issue.2 , pp. 767-772
    • Richard, M.1    Grencis, R.K.2    Humphreys, N.E.3    Renauld, J.C.4    Van Snick, J.5
  • 57
    • 0033102084 scopus 로고    scopus 로고
    • IFN α kinoid vaccine in conjunction with tritherapy, a weapon to combat immunopathogenesis in AIDS
    • Bizzini B, Volpato I, Lachgar A, Cohen P, Gringeri A. IFN α kinoid vaccine in conjunction with tritherapy, a weapon to combat immunopathogenesis in AIDS. Biomed. Pharmacother. 53(2), 87-89 (1999).
    • (1999) Biomed. Pharmacother , vol.53 , Issue.2 , pp. 87-89
    • Bizzini, B.1    Volpato, I.2    Lachgar, A.3    Cohen, P.4    Gringeri, A.5
  • 58
    • 0026681015 scopus 로고
    • Immunogenicity of combined anti-HIV and anti-suppressive vaccine preparations
    • Carelli C, Halbreich A, Bernard J et al. Immunogenicity of combined anti-HIV and anti-suppressive vaccine preparations. Biomed. Pharmacother. 46(4), 149-153 (1992).
    • (1992) Biomed. Pharmacother , vol.46 , Issue.4 , pp. 149-153
    • Carelli, C.1    Halbreich, A.2    Bernard, J.3
  • 59
    • 0033001847 scopus 로고    scopus 로고
    • Active anti-interferon-α immunization: A European-Israeli, randomized, double-blind, placebo-controlled clinical trial in 242 HIV-1-infected patients (the EURIS study)
    • Gringeri A, Musicco M, Hermans P et al. Active anti-interferon-α immunization: a European-Israeli, randomized, double-blind, placebo-controlled clinical trial in 242 HIV-1-infected patients (the EURIS study). J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 20(4), 358-370 (1999).
    • (1999) J. Acquir. Immune Defic. Syndr. Hum. Retrovirol , vol.20 , Issue.4 , pp. 358-370
    • Gringeri, A.1    Musicco, M.2    Hermans, P.3
  • 60
    • 33947110880 scopus 로고    scopus 로고
    • Paradoxical effects of cytokines in tumor immune surveillance and tumor immune escape
    • Salazar-Onfray F, Lopez MN, Mendoza-Naranjo A. Paradoxical effects of cytokines in tumor immune surveillance and tumor immune escape. Cytokine Growth Factor Rev. 18(1-2), 171-182 (2007).
    • (2007) Cytokine Growth Factor Rev , vol.18 , Issue.1-2 , pp. 171-182
    • Salazar-Onfray, F.1    Lopez, M.N.2    Mendoza-Naranjo, A.3
  • 61
    • 33847326301 scopus 로고    scopus 로고
    • VEGF kinoid vaccine, a therapeutic approach against tumor angiogenesis and metastases
    • Kinoid approach efficient in blocking angiogenesis, •
    • Rad FH, Le Buanec H, Paturance S et al. VEGF kinoid vaccine, a therapeutic approach against tumor angiogenesis and metastases. Proc. Natl Acad. Sci. USA 104(8), 2837-2842 (2007). • Kinoid approach efficient in blocking angiogenesis.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.8 , pp. 2837-2842
    • Rad, F.H.1    Le Buanec, H.2    Paturance, S.3
  • 62
    • 33847673267 scopus 로고    scopus 로고
    • Prophylactic naked DNA vaccination with the human vascular endothelial growth factor induces an anti-tumor response in C57Bl/6 mice
    • Bequet-Romero M, Ayala M, Acevedo BE et al. Prophylactic naked DNA vaccination with the human vascular endothelial growth factor induces an anti-tumor response in C57Bl/6 mice. Angiogenesis 10(1), 23-34 (2007).
    • (2007) Angiogenesis , vol.10 , Issue.1 , pp. 23-34
    • Bequet-Romero, M.1    Ayala, M.2    Acevedo, B.E.3
  • 63
    • 7444238665 scopus 로고    scopus 로고
    • Effect of an EGF-cancer vaccine on wound healing and inflammation models
    • Casaco A, Diaz Y, Ledon N et al. Effect of an EGF-cancer vaccine on wound healing and inflammation models. J. Surg. Res. 122(1), 130-134 (2004).
    • (2004) J. Surg. Res , vol.122 , Issue.1 , pp. 130-134
    • Casaco, A.1    Diaz, Y.2    Ledon, N.3
  • 64
    • 41149159650 scopus 로고    scopus 로고
    • Phase II randomized controlled trial of an epidermal growth factor vaccine in advanced non-small-cell lung cancer
    • Neninger Vinageras E, de la Torre A, Osorio Rodriguez M et al. Phase II randomized controlled trial of an epidermal growth factor vaccine in advanced non-small-cell lung cancer. J. Clin. Oncol. 26(9), 1452-1458 (2008).
    • (2008) J. Clin. Oncol , vol.26 , Issue.9 , pp. 1452-1458
    • Neninger Vinageras, E.1    de la Torre, A.2    Osorio Rodriguez, M.3
  • 65
    • 1942437446 scopus 로고    scopus 로고
    • TNF autovaccination induces self anti-TNF antibodies and inhibits metastasis in a murine melanoma model
    • Waterston AM, Salway F, Andreakos E, Butler DM, Feldmann M, Coombes RC. TNF autovaccination induces self anti-TNF antibodies and inhibits metastasis in a murine melanoma model. Br. J. Cancer 90(6), 1279-1284 (2004).
    • (2004) Br. J. Cancer , vol.90 , Issue.6 , pp. 1279-1284
    • Waterston, A.M.1    Salway, F.2    Andreakos, E.3    Butler, D.M.4    Feldmann, M.5    Coombes, R.C.6
  • 66
    • 22244450013 scopus 로고    scopus 로고
    • Phase I study of TNFα autovaccine in patients with metastatic cancer
    • Waterston AM, Gumbrell L, Bratt T et al. Phase I study of TNFα autovaccine in patients with metastatic cancer. Cancer Immunol. Immunother. 54(9), 848-857 (2005).
    • (2005) Cancer Immunol. Immunother , vol.54 , Issue.9 , pp. 848-857
    • Waterston, A.M.1    Gumbrell, L.2    Bratt, T.3
  • 67
    • 0842348085 scopus 로고    scopus 로고
    • Anticytokine Ab immune therapy: Present status and perspectives
    • Zagury D, Gallo RC. Anticytokine Ab immune therapy: present status and perspectives. Drug Discov. Today 9(2), 72-81 (2004).
    • (2004) Drug Discov. Today , vol.9 , Issue.2 , pp. 72-81
    • Zagury, D.1    Gallo, R.C.2
  • 68
    • 1042265187 scopus 로고    scopus 로고
    • Neuropathology and pathogenesis of encephalitis following amyloid-β immunization in Alzheimer's disease
    • Ferrer I, Boada Rovira M, Sanchez Guerra ML, Rey MJ, Costa-Jussa F. Neuropathology and pathogenesis of encephalitis following amyloid-β immunization in Alzheimer's disease. Brain Pathol. 14(1), 11-20 (2004).
    • (2004) Brain Pathol , vol.14 , Issue.1 , pp. 11-20
    • Ferrer, I.1    Boada Rovira, M.2    Sanchez Guerra, M.L.3    Rey, M.J.4    Costa-Jussa, F.5
  • 69
    • 0030064148 scopus 로고    scopus 로고
    • The interleukin 12 p40 gene promoter is primed by interferon γ in monocytic cells
    • Ma X, Chow JM, Gri G, Carra G et al. The interleukin 12 p40 gene promoter is primed by interferon γ in monocytic cells. J. Exp. Med. 183(1), 147-157. (1996).
    • (1996) J. Exp. Med , vol.183 , Issue.1 , pp. 147-157
    • Ma, X.1    Chow, J.M.2    Gri, G.3    Carra, G.4
  • 70
    • 0036913333 scopus 로고    scopus 로고
    • A DNA vaccine against VEGF receptor 2 prevents effective angiogenesis and inhibits tumor growth
    • Niethammer AG, Xiang R, Becker JC et al. A DNA vaccine against VEGF receptor 2 prevents effective angiogenesis and inhibits tumor growth. Nat. Med. 8(12), 1369-1375 (2002).
    • (2002) Nat. Med , vol.8 , Issue.12 , pp. 1369-1375
    • Niethammer, A.G.1    Xiang, R.2    Becker, J.C.3
  • 71
    • 0032958538 scopus 로고    scopus 로고
    • Gene therapy for severe combined immunodeficiency caused by adenosine deaminase deficiency: Improved retroviral vectors for clinical trials
    • Onodera M, Nelson DM, Sakiyama Y, Candotti F, Blaese RM. Gene therapy for severe combined immunodeficiency caused by adenosine deaminase deficiency: improved retroviral vectors for clinical trials. Acta Haematol. 101(2), 89-96 (1999).
    • (1999) Acta Haematol , vol.101 , Issue.2 , pp. 89-96
    • Onodera, M.1    Nelson, D.M.2    Sakiyama, Y.3    Candotti, F.4    Blaese, R.M.5
  • 72
    • 3843101609 scopus 로고    scopus 로고
    • Active immunization against murine TNFα peptides in mice: Generation of endogenous antibodies cross-reacting with the native cytokine and in vivo protection
    • Capini CJ, Bertin-Maghit SM, Bessis N et al. Active immunization against murine TNFα peptides in mice: generation of endogenous antibodies cross-reacting with the native cytokine and in vivo protection. Vaccine 22(23-24), 3144-3153 (2004).
    • (2004) Vaccine , vol.22 , Issue.23-24 , pp. 3144-3153
    • Capini, C.J.1    Bertin-Maghit, S.M.2    Bessis, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.