메뉴 건너뛰기




Volumn 5, Issue 1, 2008, Pages 53-61

Cardiovascular consequences of obesity and targets for treatment

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANOREXIGENIC AGENT; ANTIOBESITY AGENT; ANTIOXIDANT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CENTRAL NERVOUS SYSTEM AGENTS; DEXFENFLURAMINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FENFLURAMINE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; SIBUTRAMINE; TETRAHYDROLIPSTATIN; THIAZIDE DIURETIC AGENT; TRIACYLGLYCEROL;

EID: 57249094367     PISSN: 17406773     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddstr.2008.07.001     Document Type: Review
Times cited : (14)

References (78)
  • 1
    • 39749191084 scopus 로고    scopus 로고
    • Heart diseases and stroke statistics - 2008 update
    • Rosamond W., et al. Heart diseases and stroke statistics - 2008 update. Circulation 117 (2008) e25-e146
    • (2008) Circulation , vol.117
    • Rosamond, W.1
  • 2
    • 34548628795 scopus 로고    scopus 로고
    • Association of overweight with increased risk of coronary heart disease partly independent of blood pressure and cholesterol levels: a meta-analysis of 21 cohort studies including more than 300 000 persons
    • Bogers R.P., et al. Association of overweight with increased risk of coronary heart disease partly independent of blood pressure and cholesterol levels: a meta-analysis of 21 cohort studies including more than 300 000 persons. Arch. Intern. Med. 167 (2007) 1720-1728
    • (2007) Arch. Intern. Med. , vol.167 , pp. 1720-1728
    • Bogers, R.P.1
  • 3
    • 0036681988 scopus 로고    scopus 로고
    • Obesity and the risk of heart failure
    • Kenchaiah S., et al. Obesity and the risk of heart failure. N. Engl. J. Med. 347 (2002) 305-313
    • (2002) N. Engl. J. Med. , vol.347 , pp. 305-313
    • Kenchaiah, S.1
  • 4
    • 2442647863 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome and its relation to all-cause and cardiovascular mortality in nondiabetic European men and women
    • Hu G., et al. Prevalence of the metabolic syndrome and its relation to all-cause and cardiovascular mortality in nondiabetic European men and women. Arch. Intern. Med. 164 (2004) 1066-1076
    • (2004) Arch. Intern. Med. , vol.164 , pp. 1066-1076
    • Hu, G.1
  • 5
    • 0037021505 scopus 로고    scopus 로고
    • The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men
    • Lakka H.M., et al. The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA 288 (2002) 2709-2716
    • (2002) JAMA , vol.288 , pp. 2709-2716
    • Lakka, H.M.1
  • 6
    • 0032491203 scopus 로고    scopus 로고
    • Obesity: impact of cardiovascular disease
    • Krauss R.M., et al. Obesity: impact of cardiovascular disease. Circulation 98 (1998) 1472-1476
    • (1998) Circulation , vol.98 , pp. 1472-1476
    • Krauss, R.M.1
  • 7
    • 33646448307 scopus 로고    scopus 로고
    • Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss
    • Poirier P., et al. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss. Arterioscler. Thromb. Vasc. Biol. 26 (2006) 968-976
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 968-976
    • Poirier, P.1
  • 8
    • 0023681544 scopus 로고
    • Location and regulation of rat angiotensinogen messenger RNA
    • Cassis L.A., et al. Location and regulation of rat angiotensinogen messenger RNA. Hypertension 11 6 Pt 2 (1988) 591-596
    • (1988) Hypertension , vol.11 , Issue.6 PART 2 , pp. 591-596
    • Cassis, L.A.1
  • 9
    • 0029992124 scopus 로고    scopus 로고
    • Characterization and regulation of angiotensin II receptors in rat adipose tissue. Angiotensin receptors in adipose tissue
    • Cassis L.A., et al. Characterization and regulation of angiotensin II receptors in rat adipose tissue. Angiotensin receptors in adipose tissue. Adv. Exp. Med. Biol. 396 (1996) 39-47
    • (1996) Adv. Exp. Med. Biol. , vol.396 , pp. 39-47
    • Cassis, L.A.1
  • 10
    • 0035064965 scopus 로고    scopus 로고
    • Obesity cardiomyopathy: pathophysiology and evolution of the clinical syndrome
    • Alpert M.A. Obesity cardiomyopathy: pathophysiology and evolution of the clinical syndrome. Am. J. Med. Sci. 321 (2001) 225-236
    • (2001) Am. J. Med. Sci. , vol.321 , pp. 225-236
    • Alpert, M.A.1
  • 11
    • 4644280707 scopus 로고    scopus 로고
    • The global epidemic of obesity: are we becoming more sympathetic?
    • Davy K.P. The global epidemic of obesity: are we becoming more sympathetic?. Curr. Hypertens. Rep. 6 (2004) 241-246
    • (2004) Curr. Hypertens. Rep. , vol.6 , pp. 241-246
    • Davy, K.P.1
  • 12
    • 0032943709 scopus 로고    scopus 로고
    • C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?
    • Yudkin J.S., et al. C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?. Arterioscler. Thromb. Vasc. Biol. 19 (1999) 972-978
    • (1999) Arterioscler. Thromb. Vasc. Biol. , vol.19 , pp. 972-978
    • Yudkin, J.S.1
  • 13
    • 33645300081 scopus 로고    scopus 로고
    • Inflammation and hypertension: the search for a link
    • Pauletto P., and Rattazzi M. Inflammation and hypertension: the search for a link. Nephrol. Dial Transplant. 21 (2006) 850-853
    • (2006) Nephrol. Dial Transplant. , vol.21 , pp. 850-853
    • Pauletto, P.1    Rattazzi, M.2
  • 14
    • 8144231115 scopus 로고    scopus 로고
    • Clinical implications of obesity with specific focus on cardiovascular disease: a statement for professionals from the American Heart Association Council on Nutrition, Physical Activity, and Metabolism: endorsed by the American College of Cardiology Foundation
    • Klein S., et al. Clinical implications of obesity with specific focus on cardiovascular disease: a statement for professionals from the American Heart Association Council on Nutrition, Physical Activity, and Metabolism: endorsed by the American College of Cardiology Foundation. Circulation 110 (2004) 2952-2967
    • (2004) Circulation , vol.110 , pp. 2952-2967
    • Klein, S.1
  • 15
    • 34447511196 scopus 로고    scopus 로고
    • Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
    • Nordestgaard B.G., et al. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA 298 (2007) 299-308
    • (2007) JAMA , vol.298 , pp. 299-308
    • Nordestgaard, B.G.1
  • 16
    • 34447520136 scopus 로고    scopus 로고
    • Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women
    • Bansal S., et al. Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA 298 (2007) 309-316
    • (2007) JAMA , vol.298 , pp. 309-316
    • Bansal, S.1
  • 17
    • 0030798890 scopus 로고    scopus 로고
    • Fatty acid regulation of very low density lipoprotein production
    • Lewis G.F. Fatty acid regulation of very low density lipoprotein production. Curr. Opin. Lipidol. 8 (1997) 146-153
    • (1997) Curr. Opin. Lipidol. , vol.8 , pp. 146-153
    • Lewis, G.F.1
  • 18
    • 33845320131 scopus 로고    scopus 로고
    • Molecular regulation of HDL metabolism and function: implications for novel therapies
    • Rader D.J. Molecular regulation of HDL metabolism and function: implications for novel therapies. J. Clin. Invest. 116 (2006) 3090-3100
    • (2006) J. Clin. Invest. , vol.116 , pp. 3090-3100
    • Rader, D.J.1
  • 19
    • 0023126669 scopus 로고
    • Lipoprotein lipase in diabetes
    • Taskinen M.R. Lipoprotein lipase in diabetes. Diabetes Metab. Rev. 3 (1987) 551-570
    • (1987) Diabetes Metab. Rev. , vol.3 , pp. 551-570
    • Taskinen, M.R.1
  • 20
    • 0026781014 scopus 로고
    • Effects of weight reduction on blood lipids and lipoproteins: a meta-analysis
    • Dattilo A.M., and Kris-Etherton P.M. Effects of weight reduction on blood lipids and lipoproteins: a meta-analysis. Am. J. Clin. Nutr. 56 (1992) 320-328
    • (1992) Am. J. Clin. Nutr. , vol.56 , pp. 320-328
    • Dattilo, A.M.1    Kris-Etherton, P.M.2
  • 21
    • 34548859563 scopus 로고    scopus 로고
    • Gender-specific characteristics of atherosclerosis in menopausal women: risk factors, clinical course and strategies for prevention
    • Vitale C., et al. Gender-specific characteristics of atherosclerosis in menopausal women: risk factors, clinical course and strategies for prevention. Climacteric 10 Suppl. 2 (2007) 16-20
    • (2007) Climacteric , vol.10 , Issue.SUPPL. 2 , pp. 16-20
    • Vitale, C.1
  • 22
    • 5644231992 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
    • Ozcan U., et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306 (2004) 457-461
    • (2004) Science , vol.306 , pp. 457-461
    • Ozcan, U.1
  • 23
    • 0034652225 scopus 로고    scopus 로고
    • Lipotoxic heart disease in obese rats: implications for human obesity
    • Zhou Y.T., et al. Lipotoxic heart disease in obese rats: implications for human obesity. Proc. Natl. Acad. Sci. U S A 97 (2000) 1784-1789
    • (2000) Proc. Natl. Acad. Sci. U S A , vol.97 , pp. 1784-1789
    • Zhou, Y.T.1
  • 24
    • 0035805629 scopus 로고    scopus 로고
    • Palmitate-induced apoptosis can occur through a ceramide-independent pathway
    • Listenberger L.L., et al. Palmitate-induced apoptosis can occur through a ceramide-independent pathway. J. Biol. Chem. 276 (2001) 14890-14895
    • (2001) J. Biol. Chem. , vol.276 , pp. 14890-14895
    • Listenberger, L.L.1
  • 25
    • 33646423846 scopus 로고    scopus 로고
    • Vascular structure and function in women: relationship with body mass index
    • Olson T.P., et al. Vascular structure and function in women: relationship with body mass index. Am. J. Prev. Med. 30 (2006) 487-492
    • (2006) Am. J. Prev. Med. , vol.30 , pp. 487-492
    • Olson, T.P.1
  • 27
    • 33751534511 scopus 로고    scopus 로고
    • Vascular endothelial and smooth muscle function relates to body mass index and glucose in obese and nonobese children
    • Pena A.S., et al. Vascular endothelial and smooth muscle function relates to body mass index and glucose in obese and nonobese children. J. Clin. Endocrinol. Metab. 91 (2006) 4467-4471
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , pp. 4467-4471
    • Pena, A.S.1
  • 28
    • 36148981792 scopus 로고    scopus 로고
    • Selective resistance to vasoactive effects of insulin in muscle resistance arteries of obese Zucker (fa/fa) rats
    • Eringa E.C., et al. Selective resistance to vasoactive effects of insulin in muscle resistance arteries of obese Zucker (fa/fa) rats. Am. J. Physiol. Endocrinol. Metab. 293 (2007) E1134-E1139
    • (2007) Am. J. Physiol. Endocrinol. Metab. , vol.293
    • Eringa, E.C.1
  • 29
    • 0029819733 scopus 로고    scopus 로고
    • Chronic hyperglycemia impairs endothelial function and insulin sensitivity via different mechanisms in insulin-dependent diabetes mellitus
    • Makimattila S., et al. Chronic hyperglycemia impairs endothelial function and insulin sensitivity via different mechanisms in insulin-dependent diabetes mellitus. Circulation 94 (1996) 1276-1282
    • (1996) Circulation , vol.94 , pp. 1276-1282
    • Makimattila, S.1
  • 30
    • 0031049146 scopus 로고    scopus 로고
    • Effect of a single high-fat meal on endothelial function in healthy subjects
    • Vogel R.A., et al. Effect of a single high-fat meal on endothelial function in healthy subjects. Am. J. Cardiol. 79 (1997) 350-354
    • (1997) Am. J. Cardiol. , vol.79 , pp. 350-354
    • Vogel, R.A.1
  • 31
    • 33846263404 scopus 로고    scopus 로고
    • Adipocytokines - novel link between inflammation and vascular function?
    • Guzik T.J., et al. Adipocytokines - novel link between inflammation and vascular function?. J. Physiol. Pharmacol. 57 (2006) 505-528
    • (2006) J. Physiol. Pharmacol. , vol.57 , pp. 505-528
    • Guzik, T.J.1
  • 32
    • 33646896940 scopus 로고    scopus 로고
    • Obesity, weight loss, and vascular function
    • Brook R.D. Obesity, weight loss, and vascular function. Endocrine 29 (2006) 21-25
    • (2006) Endocrine , vol.29 , pp. 21-25
    • Brook, R.D.1
  • 33
    • 0037907471 scopus 로고    scopus 로고
    • Pivotal role of nitric oxide in the control of blood pressure after leptin administration
    • Fruhbeck G. Pivotal role of nitric oxide in the control of blood pressure after leptin administration. Diabetes 48 (1999) 903-908
    • (1999) Diabetes , vol.48 , pp. 903-908
    • Fruhbeck, G.1
  • 34
    • 33749001704 scopus 로고    scopus 로고
    • Leptin is an endothelial-independent vasodilator in humans with coronary artery disease: evidence for tissue specificity of leptin resistance
    • Momin A.U., et al. Leptin is an endothelial-independent vasodilator in humans with coronary artery disease: evidence for tissue specificity of leptin resistance. Eur. Heart J. 27 (2006) 2294-2299
    • (2006) Eur. Heart J. , vol.27 , pp. 2294-2299
    • Momin, A.U.1
  • 35
    • 34147182630 scopus 로고    scopus 로고
    • Effects of CRP infusion on endothelial function and coagulation in normocholesterolemic and hypercholesterolemic subjects
    • Bisoendial R.J., et al. Effects of CRP infusion on endothelial function and coagulation in normocholesterolemic and hypercholesterolemic subjects. J. Lipid Res. 48 (2007) 952-960
    • (2007) J. Lipid Res. , vol.48 , pp. 952-960
    • Bisoendial, R.J.1
  • 36
    • 34548121876 scopus 로고    scopus 로고
    • Adipose tissue, inflammation and endothelial dysfunction
    • Chudek J., and Wiecek A. Adipose tissue, inflammation and endothelial dysfunction. Pharmacol. Rep. 58 Suppl. (2006) 81-88
    • (2006) Pharmacol. Rep. , vol.58 , Issue.SUPPL , pp. 81-88
    • Chudek, J.1    Wiecek, A.2
  • 37
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P. Inflammation in atherosclerosis. Nature 420 (2002) 868-874
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 38
    • 33645755859 scopus 로고    scopus 로고
    • Endothelial dysfunction: a comprehensive appraisal
    • Esper R.J., et al. Endothelial dysfunction: a comprehensive appraisal. Cardiovasc. Diabetol. 5 (2006) 4
    • (2006) Cardiovasc. Diabetol. , vol.5 , pp. 4
    • Esper, R.J.1
  • 39
    • 0242577299 scopus 로고    scopus 로고
    • IL-6 is produced by splenocytes derived from CMV-infected mice in response to CMV antigens, and induces MCP-1 production by endothelial cells: a new mechanistic paradigm for infection-induced atherogenesis
    • Rott D., et al. IL-6 is produced by splenocytes derived from CMV-infected mice in response to CMV antigens, and induces MCP-1 production by endothelial cells: a new mechanistic paradigm for infection-induced atherogenesis. Atherosclerosis 170 (2003) 223-228
    • (2003) Atherosclerosis , vol.170 , pp. 223-228
    • Rott, D.1
  • 40
    • 20844449693 scopus 로고    scopus 로고
    • Impact of interleukin-6 on plaque development and morphology in experimental atherosclerosis
    • Scheiffer B., et al. Impact of interleukin-6 on plaque development and morphology in experimental atherosclerosis. Circulation 110 (2004) 3493-3500
    • (2004) Circulation , vol.110 , pp. 3493-3500
    • Scheiffer, B.1
  • 41
    • 0026776760 scopus 로고
    • Induction of low density lipoprotein receptor and a transcription factor SP-1 by tumor necrosis factor in human microvascular endothelial cells
    • Hamanaka R., et al. Induction of low density lipoprotein receptor and a transcription factor SP-1 by tumor necrosis factor in human microvascular endothelial cells. J. Biol. Chem. 267 (1992) 13160-13165
    • (1992) J. Biol. Chem. , vol.267 , pp. 13160-13165
    • Hamanaka, R.1
  • 42
    • 0033597123 scopus 로고    scopus 로고
    • Inflammatory cytokines and oxidized low density lipoproteins increase endothelial cell expression of membrane type 1-matrix metalloproteinase
    • Rajavashisth T.B., et al. Inflammatory cytokines and oxidized low density lipoproteins increase endothelial cell expression of membrane type 1-matrix metalloproteinase. J. Biol. Chem. 274 (1999) 11924-11929
    • (1999) J. Biol. Chem. , vol.274 , pp. 11924-11929
    • Rajavashisth, T.B.1
  • 43
    • 33748970803 scopus 로고    scopus 로고
    • Leptin and atherosclerosis
    • Beltowski J. Leptin and atherosclerosis. Atherosclerosis 189 (2006) 47-60
    • (2006) Atherosclerosis , vol.189 , pp. 47-60
    • Beltowski, J.1
  • 44
    • 33846505483 scopus 로고    scopus 로고
    • Imaging aortic matrix metabolism: mirabile visu!
    • Towler D.A. Imaging aortic matrix metabolism: mirabile visu!. Circulation 115 (2007) 297-299
    • (2007) Circulation , vol.115 , pp. 297-299
    • Towler, D.A.1
  • 45
    • 0037341535 scopus 로고    scopus 로고
    • Obesity: risk of venous thrombosis and the interaction with coagulation factor levels and oral contraceptive use
    • Abdollahi M., et al. Obesity: risk of venous thrombosis and the interaction with coagulation factor levels and oral contraceptive use. Thromb. Haemost. 89 (2003) 493-498
    • (2003) Thromb. Haemost. , vol.89 , pp. 493-498
    • Abdollahi, M.1
  • 46
    • 15444366991 scopus 로고    scopus 로고
    • Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation
    • Dandona P., et al. Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation. Circulation 111 (2005) 1448-1454
    • (2005) Circulation , vol.111 , pp. 1448-1454
    • Dandona, P.1
  • 47
    • 0032840328 scopus 로고    scopus 로고
    • Patterns of body fat deposition in youth and their relation to left ventricular markers of adverse cardiovascular prognosis
    • Mensah G.A., et al. Patterns of body fat deposition in youth and their relation to left ventricular markers of adverse cardiovascular prognosis. Am. J. Cardiol. 84 (1999) 583-588
    • (1999) Am. J. Cardiol. , vol.84 , pp. 583-588
    • Mensah, G.A.1
  • 48
    • 1942420839 scopus 로고    scopus 로고
    • Alterations in left ventricular structure and function in young healthy obese women: assessment by echocardiography and tissue Doppler imaging
    • Peterson L.R., et al. Alterations in left ventricular structure and function in young healthy obese women: assessment by echocardiography and tissue Doppler imaging. J. Am. Coll. Cardiol. 43 (2004) 1399-1404
    • (2004) J. Am. Coll. Cardiol. , vol.43 , pp. 1399-1404
    • Peterson, L.R.1
  • 49
    • 8544283794 scopus 로고    scopus 로고
    • Alterations of left ventricular myocardial characteristics associated with obesity
    • Wong C.Y., et al. Alterations of left ventricular myocardial characteristics associated with obesity. Circulation 110 (2004) 3081-3087
    • (2004) Circulation , vol.110 , pp. 3081-3087
    • Wong, C.Y.1
  • 50
    • 0242288653 scopus 로고    scopus 로고
    • Adiposity contributes to differences in left ventricular structure and diastolic function with age in healthy men
    • Gates P.E., et al. Adiposity contributes to differences in left ventricular structure and diastolic function with age in healthy men. J. Clin. Endocrinol. Metab. 88 (2003) 4884-4890
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 4884-4890
    • Gates, P.E.1
  • 51
    • 0026667805 scopus 로고
    • The influence of obesity on left ventricular filling and systolic function
    • Stoddard M.F., et al. The influence of obesity on left ventricular filling and systolic function. Am. Heart J. 124 (1992) 694-699
    • (1992) Am. Heart J. , vol.124 , pp. 694-699
    • Stoddard, M.F.1
  • 52
    • 0028879983 scopus 로고
    • Obesity and left ventricular diastolic dysfunction
    • Berkalp B., et al. Obesity and left ventricular diastolic dysfunction. Int. J. Cardiol. 52 (1995) 23-26
    • (1995) Int. J. Cardiol. , vol.52 , pp. 23-26
    • Berkalp, B.1
  • 53
    • 0023129491 scopus 로고
    • Cardiac mechanics and function in obese normotensive persons with normal coronary arteries
    • Carabello B.A., and Gittens L. Cardiac mechanics and function in obese normotensive persons with normal coronary arteries. Am. J. Cardiol. 59 (1987) 469-473
    • (1987) Am. J. Cardiol. , vol.59 , pp. 469-473
    • Carabello, B.A.1    Gittens, L.2
  • 54
    • 0035889569 scopus 로고    scopus 로고
    • Relation of various degrees of body mass index in patients with systemic hypertension to left ventricular mass, cardiac output, and peripheral resistance (The Hypertension Genetic Epidemiology Network Study)
    • Palmieri V., et al. Relation of various degrees of body mass index in patients with systemic hypertension to left ventricular mass, cardiac output, and peripheral resistance (The Hypertension Genetic Epidemiology Network Study). Am. J. Cardiol. 88 (2001) 1163-1168
    • (2001) Am. J. Cardiol. , vol.88 , pp. 1163-1168
    • Palmieri, V.1
  • 55
    • 13444268937 scopus 로고    scopus 로고
    • Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy
    • Chiu H.C., et al. Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy. Circ. Res. 96 (2005) 225-233
    • (2005) Circ. Res. , vol.96 , pp. 225-233
    • Chiu, H.C.1
  • 56
    • 0037315085 scopus 로고    scopus 로고
    • Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice
    • Aasum E., et al. Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice. Diabetes 52 (2003) 434-441
    • (2003) Diabetes , vol.52 , pp. 434-441
    • Aasum, E.1
  • 57
    • 0035061419 scopus 로고    scopus 로고
    • A novel mouse model of lipotoxic cardiomyopathy
    • Chiu H.C., et al. A novel mouse model of lipotoxic cardiomyopathy. J. Clin. Invest. 107 (2001) 813-822
    • (2001) J. Clin. Invest. , vol.107 , pp. 813-822
    • Chiu, H.C.1
  • 58
    • 2442492971 scopus 로고    scopus 로고
    • Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women
    • Peterson L.R., et al. Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women. Circulation 109 (2004) 2191-2196
    • (2004) Circulation , vol.109 , pp. 2191-2196
    • Peterson, L.R.1
  • 59
    • 0037371754 scopus 로고    scopus 로고
    • Myocardial triglycerides and systolic function in humans: in vivo evaluation by localized proton spectroscopy and cardiac imaging
    • Szczepaniak L.S., et al. Myocardial triglycerides and systolic function in humans: in vivo evaluation by localized proton spectroscopy and cardiac imaging. Magn. Reson. Med. 49 (2003) 417-423
    • (2003) Magn. Reson. Med. , vol.49 , pp. 417-423
    • Szczepaniak, L.S.1
  • 60
    • 7744234747 scopus 로고    scopus 로고
    • Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart
    • Sharma S., et al. Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart. FASEB J. 18 (2004) 1692-1700
    • (2004) FASEB J. , vol.18 , pp. 1692-1700
    • Sharma, S.1
  • 61
    • 33748419255 scopus 로고    scopus 로고
    • Association of plasma free fatty acids and left ventricular diastolic function in patients with clinically severe obesity
    • Leichman J.G., et al. Association of plasma free fatty acids and left ventricular diastolic function in patients with clinically severe obesity. Am. J. Clin. Nutr. 84 (2006) 336-341
    • (2006) Am. J. Clin. Nutr. , vol.84 , pp. 336-341
    • Leichman, J.G.1
  • 62
    • 0032952718 scopus 로고    scopus 로고
    • Obesity is associated with increased myocardial oxidative stress
    • Vincent H.K., et al. Obesity is associated with increased myocardial oxidative stress. Int. J. Obes. Relat. Metab. Disord 23 (1999) 67-74
    • (1999) Int. J. Obes. Relat. Metab. Disord , vol.23 , pp. 67-74
    • Vincent, H.K.1
  • 63
    • 33846250408 scopus 로고    scopus 로고
    • The peroxynitrite decomposition catalyst FP15 improves ageing-associated cardiac and vascular dysfunction
    • Radovits T., et al. The peroxynitrite decomposition catalyst FP15 improves ageing-associated cardiac and vascular dysfunction. Mech. Ageing Dev. 128 (2007) 173-181
    • (2007) Mech. Ageing Dev. , vol.128 , pp. 173-181
    • Radovits, T.1
  • 65
    • 0021949444 scopus 로고
    • Effect of weight loss on cardiac chamber size, wall thickness and left ventricular function in morbid obesity
    • Alpert M.A., et al. Effect of weight loss on cardiac chamber size, wall thickness and left ventricular function in morbid obesity. Am. J. Cardiol. 55 (1985) 783-786
    • (1985) Am. J. Cardiol. , vol.55 , pp. 783-786
    • Alpert, M.A.1
  • 66
    • 34548848059 scopus 로고    scopus 로고
    • Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins
    • Boudina S., et al. Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins. Diabetes 56 (2007) 2457-2466
    • (2007) Diabetes , vol.56 , pp. 2457-2466
    • Boudina, S.1
  • 67
    • 0037737900 scopus 로고    scopus 로고
    • A randomized trial of a low-carbohydrate diet for obesity
    • Foster G.D., et al. A randomized trial of a low-carbohydrate diet for obesity. N. Engl. J. Med. 348 (2003) 2082-2090
    • (2003) N. Engl. J. Med. , vol.348 , pp. 2082-2090
    • Foster, G.D.1
  • 68
    • 33750993168 scopus 로고    scopus 로고
    • Nonpharmacologic therapy for hypertension: does it really work?
    • Tejada T., et al. Nonpharmacologic therapy for hypertension: does it really work?. Curr. Cardiol. Rep. 8 (2006) 418-424
    • (2006) Curr. Cardiol. Rep. , vol.8 , pp. 418-424
    • Tejada, T.1
  • 69
    • 34547820945 scopus 로고    scopus 로고
    • Metabolic syndrome: treatment of hypertensive patients
    • Israili Z.H., et al. Metabolic syndrome: treatment of hypertensive patients. Am. J. Ther. 14 (2007) 386-402
    • (2007) Am. J. Ther. , vol.14 , pp. 386-402
    • Israili, Z.H.1
  • 70
    • 10844295087 scopus 로고    scopus 로고
    • Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery
    • Sjostrom L., et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N. Engl. J. Med. 351 (2004) 2683-2693
    • (2004) N. Engl. J. Med. , vol.351 , pp. 2683-2693
    • Sjostrom, L.1
  • 71
    • 2942526828 scopus 로고    scopus 로고
    • Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease
    • Klein S., et al. Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. N. Engl. J. Med. 350 (2004) 2549-2557
    • (2004) N. Engl. J. Med. , vol.350 , pp. 2549-2557
    • Klein, S.1
  • 72
    • 34548075820 scopus 로고    scopus 로고
    • Long-term mortality after gastric bypass surgery
    • Adams T.D., et al. Long-term mortality after gastric bypass surgery. N. Engl. J. Med. 357 (2007) 753-761
    • (2007) N. Engl. J. Med. , vol.357 , pp. 753-761
    • Adams, T.D.1
  • 73
    • 34548090763 scopus 로고    scopus 로고
    • Effects of bariatric surgery on mortality in Swedish obese subjects
    • Sjostrom L., et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N. Engl. J. Med. 357 (2007) 741-752
    • (2007) N. Engl. J. Med. , vol.357 , pp. 741-752
    • Sjostrom, L.1
  • 74
    • 0028873028 scopus 로고
    • Improvement of left ventricular morphology and function in obese subjects following a diet and exercise program
    • Wirth A., and Kroger H. Improvement of left ventricular morphology and function in obese subjects following a diet and exercise program. Int. J. Obes. Relat. Metab. Disord. 19 (1995) 61-66
    • (1995) Int. J. Obes. Relat. Metab. Disord. , vol.19 , pp. 61-66
    • Wirth, A.1    Kroger, H.2
  • 75
    • 0028908380 scopus 로고
    • Reduction of weight and left ventricular mass with serotonin uptake inhibition in obese patients with systemic hypertension
    • Jordan J., et al. Reduction of weight and left ventricular mass with serotonin uptake inhibition in obese patients with systemic hypertension. Am. J. Cardiol. 75 (1995) 743-744
    • (1995) Am. J. Cardiol. , vol.75 , pp. 743-744
    • Jordan, J.1
  • 76
    • 0033062820 scopus 로고    scopus 로고
    • A weight reduction and weight maintenance program with long-lasting improvement in left ventricular mass and blood pressure
    • Himeno E., et al. A weight reduction and weight maintenance program with long-lasting improvement in left ventricular mass and blood pressure. Am. J. Hypertens. 12 (1999) 682-690
    • (1999) Am. J. Hypertens. , vol.12 , pp. 682-690
    • Himeno, E.1
  • 77
    • 33751573397 scopus 로고    scopus 로고
    • Moderate weight loss decreases myocardial oxygen consumption and cardiac work in obese men and women
    • Peterson L.R., et al. Moderate weight loss decreases myocardial oxygen consumption and cardiac work in obese men and women. J. Am. Coll. Cardiol. 47 (2006) 105A
    • (2006) J. Am. Coll. Cardiol. , vol.47
    • Peterson, L.R.1
  • 78
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: human gut microbes associated with obesity
    • Ley R.E., et al. Microbial ecology: human gut microbes associated with obesity. Nature 444 (2006) 1022-1023
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.