Obesity is associated with increased myocardial oxidative stress

International Journal of Obesity

Volumn 23, Issue 1, 1999, Pages 67-74

  Vincent, Heather K ^a   Powers, S K ^a   Stewart, D J ^a   Shanely, R A ^a   Demirel, H ^a   Naito, H ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

Antioxidant enzymes; Lipid peroxidation; Myocardium; Obesity; Reactive oxygen species (ROS)

Indexed keywords

ANTIOXIDANT; CATALASE; CITRATE SYNTHASE; CUMENE HYDROPEROXIDE; GLUTATHIONE PEROXIDASE; HEAT SHOCK PROTEIN; IRON; LIPID HYDROPEROXIDE; MANGANESE DERIVATIVE; OXIDOREDUCTASE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID; THIOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENZYME ACTIVITY; HEART LEFT VENTRICLE; HEART MUSCLE; LEAN BODY WEIGHT; LIPID PEROXIDATION; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; TISSUE LEVEL;

ANIMALIA; FELIS CATUS;

EID: 0032952718     PISSN: 03070565     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ijo.0800761     Document Type: Article

References (33)

1. 1 Van Gaal LF, Zhang A, Steijaert MM, DeLeeuw IH. Human obesity: from lipid abnormalities to lipid oxidation. Int J Obes 1995; 9(Suppl 3): S21-S26.
2. 2 Ji L. Exercise and oxidative stress: role of the cellular antioxidant systems. Exer Sport Sci Rev 1995; 23: 135-166.
3. 3 Kukreja RC, Hess ML. The oxygen free radical system: from equations through membrane-protein interactions to cardiovascular injury and protection. Cardiovasc Res 1992; 26: 641-655.
4. 4 Shattock MJ, Haddock PS. Oxidant stress and the heart: modulation of ion transport mechanisms during ischemia and reperfusion. In: Immunopharmacology of Free Radical Species. Academic Press: Baltimore, 1995.
5. 5 Messerli FYH, Ketelhut R. Left ventricular hypertrophy: a pressure-independent cardiovascular risk factor. J Cardiopulm Pharm 1993; 22(Suppl. 1): S7-S13.
6. 6 Messerli FH, Nunez BD, Ventura HO, Snyder DW. Overweight and sudden death: increased ventricular ectopy in cardiopathy of obesity. Arch Intern Med 1987; 147: 1725-1728.
7. 7 Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine (2nd edn). Clarendon Press: Oxford, 1989.
8. 8 Locke M. Cellular stress response to exercise: role of stress proteins. Exer Sport Sci Rev 1997; 25: 105-136.
9. 9 Flohe L, Gunzler W. Assays of glutathione peroxidase. Methods Enzymol 1984; 105: 114-121.
10. 10 Powers SK, Demirel H, Vincent HK, Coombes JS, Naito H, Ward KH, Shanely RA, Jessup J. Exercise training improves myocardial tolerance to in vivo ischemia-reperfusion in the rat. Am J Physiol, 1998; in review.
11. 11 Das DK, Engleman RM, Y Kimura. Molecular adaptation of the cellular defenses following preconditioning of the heart by repeated ischemia. Cardiovasc Res 1993; 27: 578-584.
12. 12 Salo DC, Donovan CM, Davies KJA. HSP70 and other heat shock or oxidative stress proteins are induced in skeletal muscle, heart, and liver during exercise. Free Rad Biol Med 1991; 11: 239-246.
13. 13 Burdon RH, van Knippenberg PH (eds). Lipid extraction procedures. In: Burdon RH, van Knippenberg PH (eds). Laboratory Techniques in Biochemistry and Molecular Biology. vol 3 (part 2). Elsevier: Amsterdam, 1986, pp 100-107.
14. 14 Srere P. Citrate Synthase. Methods Enzymol 1969; 3: 3-3-11.
15. 15 Oyanagui Y. Reevaluation of assay methods and establishment of kit for superoxide dismutase activity. Anal Biochem 1984; 142: 290-296.
16. 16 Aebi H. Catalase in vitro. Methods Enzymol 1984; 105: 121-126.
17. 17 Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxidation in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351-359.
18. 18 Hermes-Lima M, Willmore W, Storey K. Quantification of lipid peroxidation in tissue extracts based on Fe(III) xylenol orange formation. Free Rad Biol Med 1995; 19: 271-280.
19. 19 Locke M, Tanguay R, Klabunde R, Ianuzzo D. Enhanced postischemic myocardial recovery following induction of HSP72. Am J Physiol 1995; 38: H320-H325.
20. 20 Cox RH, Kitka DC. Age-related changes in thoracic aorta of obese Zucker rats. Am J Physiol 1992 31: H1548-H1556.
21. 21 Kurtz TW, Morris RC and Pershadsingh HA. The Zucker fatty rat as a genetic model of obesity and hypertension. Hypertension 1989; 13: 896-901.
22. 22 Pawloski CM, Kanagy NL, Mortensen LH, Fink GD. Obese Zucker rats are normotensive on normal and increased sodium intake. Hypertension 1992; 19 (suppl 1): 190-195.
23. 23 Yu B. Cellular defenses against damage from reactive oxygen species. Physiol Rev 1994; 74: 139-162.
24. 24 Blake DR, Allen RE, Lunec J. Free radicals in biological systems a review oriented to inflammatory processes. Br Med Bull 1987; 43: 371-385.
25. 25 Koneru B, Reddy MC, Dela Torre AN, Patel D, Ippolito T and Ferrante RJ. Studies of hepatic warm ischemia in the obese Zucker Rat. Transplantation 1995; 59: 942-946.
26. 26 Regnstrom J, Nilsson J, Tomvall P, Landau C, Hamster A. Susceptibility to low-density lipoprotein oxidation and coronary atherosclerosis in man. Lancet 1992; 339: 1183-1186.
27. 27 Barclay JK, Hansel M. Free radicals contribute to oxidative skeletal muscle fatigue. Can J Physiol Pharmacol 1991; 69: 279-284.
28. 28 Decsi T, Molnar D, Koletzko B. Reduced plasma concentrations of alpha-tocopherol and beta-carotene in obese boys. J Pediatr 1997; 130 (4): 653-655.
29. 29 De Bono DP. Free radicals and antioxidants in vascular biology: the roles of reaction kinetics, environment and substrate turnover. Q J Med 1994; 87: 445-453.
30. 30 Mizzen LA, Chang C, Garrels JI, Welch WJ. Identification, characterization and purification of two mammalian stress proteins present in the mitochondria, grp 75, a member of the hsp 70 family and hsp 58, homolog of the bacterial groEL protein. J Biol Chem 1989; 264: 20664-20675.
31. 31 Bray GA. The Zucker fatty rat: a review. Fed Proc 1977; 36: 148-153.
32. 32 Hoshida S, Nishida M, Yamashita N, Igarashi J, Aoki K, Hori M, Kuzuya T, Tada M. Heme oxygenase-1 expression and its relation to oxidative stress during primary culture of cardiomyocytes. J Mol Cell Cardiol 1996; 28: 1845-1855.
33. 33 Joceylin P. Spectrophotometric assay of thiols. Methods Enzymol 1989; 143: 44-55.