Activation of liver X receptors inhibits pancreatic islet beta cell proliferation through cell cycle arrest

Diabetologia

Volumn 52, Issue 1, 2009, Pages 125-135

  Meng, Z X ^a   Nie, J ^a   Ling, J J ^a   Sun, J X ^b   Zhu, Y X ^a   Gao, L ^a   Lv, J H ^a   Zhu, D Y ^a   Sun, Y J ^a   Han, X ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

Beta cell; Cell cycle; Islet; LXR; P27; Proliferation

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BROXURIDINE; DNA; LIVER X RECEPTOR; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; PROTEIN P27;

ADENOVIRUS; ANIMAL CELL; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CELL VIABILITY; CHEMICAL LABELING; COMPETITIVE INHIBITION; CONTROLLED STUDY; DNA DETERMINATION; DNA RESPONSIVE ELEMENT; DNA SYNTHESIS; FLOW CYTOMETRY; FLUOROMETRY; GENE ACTIVITY; GENE EXPRESSION; GENETIC ANALYSIS; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; RNA INTERFERENCE; TRANSACTIVATION; TRANSIENT TRANSFECTION;

ANIMALS; CELL CYCLE; CELL DIVISION; CELL SURVIVAL; CRICETINAE; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GENES, REPORTER; INSULIN-SECRETING CELLS; MICE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 57249094223     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-008-1174-x     Document Type: Article

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