Broadening of neutralization activity to directly block a dominant antibody-driven SARS-coronavirus evolution pathway

PLoS Pathogens

Volumn 4, Issue 11, 2008, Pages

  Sui, Jianhua ^a,b   Aird, Daniel R ^a,b   Tamin, Azaibi ^c   Murakami, Akikazu ^a,b   Yan, Meiying ^d   Yammanuru, Anuradha ^a,b   Jing, Huaiqi ^d   Kan, Biao ^d   Liu, Xin ^a,b   Zhu, Quan ^a,b   Yuan, Qing An ^e   Adams, Gregory P ^e   Bellini, William J ^c   Xu, Jianguo ^d   Anderson, Larry J ^c   Marasco, Wayne A ^a,b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c NATL CENTER FOR INFECTIOUS DISEASES   (United States)

^d CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^e FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYTIDINE DEAMINASE; EPITOPE; NEUTRALIZING ANTIBODY; VIRUS ANTIBODY; VIRUS PROTEIN; AICDA (ACTIVATION INDUCED CYTIDINE DEAMINASE); AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); ANTISERUM; UNCLASSIFIED DRUG;

ANTIBODY RESPONSE; ANTIVIRAL THERAPY; ARTICLE; ENZYME ACTIVATION; HUMAN; IMMUNE RESPONSE; IN VITRO STUDY; MOLECULAR EVOLUTION; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN STRUCTURE; SARS CORONAVIRUS; SOMATIC HYPERMUTATION; VIRUS INFECTION; VIRUS STRAIN; VIRUS TRANSMISSION; ANIMAL; COMPLEMENTARITY DETERMINING REGION; EVOLUTION; GENETIC SELECTION; GENETICS; IMMUNOLOGY;

ANIMALIA; SARS CORONAVIRUS;

ANIMALS; ANTIBODIES, VIRAL; COMPLEMENTARITY DETERMINING REGIONS; CYTIDINE DEAMINASE; EPITOPES; EVOLUTION; HUMANS; IMMUNE SERA; SARS VIRUS; SELECTION (GENETICS);

EID: 57149089660     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000197     Document Type: Article

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