Electrophilic S-trifluoromethylation of cysteine side chains in α- and β-peptides: Isolation of trifluoromethylated sandostatin® (octreotide) derivatives

Helvetica Chimica Acta

Volumn 91, Issue 11, 2008, Pages 2035-2056

  Caponea, Stefania ^a   Kieltschb, Iris ^a   Flögela, Oliver ^a   Lelaisa, Gerald ^a   Togni, Antonio ^a   Seebach, Dieter ^a  

^a LABORATORY OF INORGANIC CHEMISTRY   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CD SPECTROSCOPIES; HIGH RESOLUTIONS; INDOLE RINGS; MEDICINAL CHEMISTRIES; NMR SPECTROSCOPIES; OCTREOTIDE; SIDE CHAINS; TRIFLUORO METHYLS; TRIFLUOROMETHYLATION;

AMINES; CARBOXYLATION; CHROMATOGRAPHIC ANALYSIS; FUNCTIONAL GROUPS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDES; PROTEINS;

GROUP TECHNOLOGY;

ALANINE; CYSTEINE; FLUORINE DERIVATIVE; OCTREOTIDE; PEPTIDE; TRYPTOPHAN;

ARTICLE; CHEMICAL MODIFICATION; CHROMATOGRAPHY; CIRCULAR DICHROISM; FLUORINATION; MASS SPECTROMETRY; METHYLATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL;

EID: 57149087723     PISSN: 0018019X     EISSN: None     Source Type: Journal    
DOI: 10.1002/hlca.200890217     Document Type: Article

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