Role of NF-κB and PI 3-kinase/Akt in TNF-α-induced cytotoxicity in microvascular endothelial cells

American Journal of Physiology - Renal Physiology

Volumn 295, Issue 4, 2008, Pages

  Zhou, Zhu ^b   Gengaro, Patricia ^a   Wang, Wei ^a   Wang, Xue Qing ^a   Li, Chunling ^a   Faubel, Sarah ^a   Rivard, Christopher ^a   Schrier, Robert W ^a,c  

^a UNIVERSITY OF COLORADO   (United States)

^b KUNMING MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

Cell culture; Endotoxemia; LY294002; PDTC; Sepsis

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PYRROLIDINE DITHIOCARBAMATE; RANTES; TUMOR NECROSIS FACTOR ALPHA; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ANTIOXIDANT; CHROMONE DERIVATIVE; DRUG DERIVATIVE; ENZYME INHIBITOR; MORPHOLINE DERIVATIVE; NOS2 PROTEIN, MOUSE; PROLINE; PROLINEDITHIOCARBAMATE; THIOCARBAMIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; ENDOTHELIUM CELL; ENZYME ACTIVATION; INHIBITION KINETICS; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; VASCULAR ENDOTHELIUM; ANIMAL; CELL CULTURE; CELL SURVIVAL; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENDOTOXEMIA; METABOLISM; PHYSIOLOGY; SEPSIS; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIOXIDANTS; CELL SURVIVAL; CELLS, CULTURED; CHROMONES; ENDOTHELIAL CELLS; ENDOTOXEMIA; ENZYME INHIBITORS; INTERLEUKIN-1BETA; INTERLEUKIN-6; MAP KINASE SIGNALING SYSTEM; MICE; MORPHOLINES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PROLINE; PROTO-ONCOGENE PROTEINS C-AKT; SEPSIS; THIOCARBAMATES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 57049100959     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00066.2008     Document Type: Article

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