메뉴 건너뛰기




Volumn 7, Issue 22, 2008, Pages 3525-3533

AURKA overexpression accompanies dysregulation of DNA-damage response genes in invasive urothelial cell carcinoma

Author keywords

aCGH; AURKA; Cell cycle; DDR; Expression microarray; UCC

Indexed keywords

AURKA PROTEIN; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

EID: 56449127792     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.7.22.7042     Document Type: Article
Times cited : (15)

References (51)
  • 4
    • 0034969685 scopus 로고    scopus 로고
    • Billerey C, Chopin D, Aubriot-Lorton MH, Ricol D, Gil Diez de Medina S, Van Rhijn B, Bralet MP, Lefrere-Belda MA, Lahaye JB, Abbou CC, Bonaventure J, Zafrani ES, van der Kwast T, Thiery JP, Radvanyi F. Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors. Am J Pathol 2001; 158:1955-9.
    • Billerey C, Chopin D, Aubriot-Lorton MH, Ricol D, Gil Diez de Medina S, Van Rhijn B, Bralet MP, Lefrere-Belda MA, Lahaye JB, Abbou CC, Bonaventure J, Zafrani ES, van der Kwast T, Thiery JP, Radvanyi F. Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors. Am J Pathol 2001; 158:1955-9.
  • 5
    • 41849120477 scopus 로고    scopus 로고
    • Chromosomal instability in bladder cancer
    • Epub ahead of print
    • Florl AR, Schulz WA. Chromosomal instability in bladder cancer. Arch Toxicol 2008; [Epub ahead of print].
    • (2008) Arch Toxicol
    • Florl, A.R.1    Schulz, W.A.2
  • 6
    • 0029808466 scopus 로고    scopus 로고
    • Cell cycle checkpoints: Preventing an identity crisis
    • Elledge SJ. Cell cycle checkpoints: preventing an identity crisis. Science 1996; 274:1664-72.
    • (1996) Science , vol.274 , pp. 1664-1672
    • Elledge, S.J.1
  • 9
    • 0035902108 scopus 로고    scopus 로고
    • Genome maintenance mechanisms for preventing cancer
    • Hoeijmakers JH. Genome maintenance mechanisms for preventing cancer. Nature 2001; 411:366-74.
    • (2001) Nature , vol.411 , pp. 366-374
    • Hoeijmakers, J.H.1
  • 10
    • 3242890575 scopus 로고    scopus 로고
    • Mammalian cell cycle checkpoints: Signalling pathways and their organization in space and time
    • Lukas J, Lukas C, Bartek J. Mammalian cell cycle checkpoints: signalling pathways and their organization in space and time. DNA Repair (Amst) 2004; 3:997-1007.
    • (2004) DNA Repair (Amst) , vol.3 , pp. 997-1007
    • Lukas, J.1    Lukas, C.2    Bartek, J.3
  • 11
    • 9244251125 scopus 로고    scopus 로고
    • Cell cycle checkpoints and cancer
    • Kastan MB, Bartek J. Cell cycle checkpoints and cancer. Nature 2004; 432:316-23.
    • (2004) Nature , vol.432 , pp. 316-323
    • Kastan, M.B.1    Bartek, J.2
  • 12
    • 17244380682 scopus 로고    scopus 로고
    • Aborting the Birth of Cancer
    • Venkitaraman A. Aborting the Birth of Cancer. Nature 2005; 434:829-30.
    • (2005) Nature , vol.434 , pp. 829-830
    • Venkitaraman, A.1
  • 13
    • 1842486792 scopus 로고    scopus 로고
    • The spindle checkpoint, aneuploidy and cancer
    • Bharadwaj R, Yu H. The spindle checkpoint, aneuploidy and cancer. Oncogene 2004; 23:2016-27.
    • (2004) Oncogene , vol.23 , pp. 2016-2027
    • Bharadwaj, R.1    Yu, H.2
  • 14
    • 8444220396 scopus 로고    scopus 로고
    • Overexpression of Aurora-A contributes to malignant development of human esophageal squamous cell carcinoma
    • Tong T, Zhong Y, Kong J, et al. Overexpression of Aurora-A contributes to malignant development of human esophageal squamous cell carcinoma. Clin Cancer Res 2004; 10:7304-10.
    • (2004) Clin Cancer Res , vol.10 , pp. 7304-7310
    • Tong, T.1    Zhong, Y.2    Kong, J.3
  • 15
    • 16344361846 scopus 로고    scopus 로고
    • The clinical significance of Aurora-A/STK15/ BTAK expression in human esophageal squamous cell carcinoma
    • Tanaka E, Hashimoto Y, Ito T, et al. The clinical significance of Aurora-A/STK15/ BTAK expression in human esophageal squamous cell carcinoma. Clin Cancer Res 2005; 11:1827-34.
    • (2005) Clin Cancer Res , vol.11 , pp. 1827-1834
    • Tanaka, E.1    Hashimoto, Y.2    Ito, T.3
  • 16
    • 0037343237 scopus 로고    scopus 로고
    • Overexpression of oncogenic STK15/BTAK/Aurora A kinase in human pancreatic cancer
    • Li D, Zhu J, Firozi PF, et al. Overexpression of oncogenic STK15/BTAK/Aurora A kinase in human pancreatic cancer. Clin Cancer Res 2003; 9:991-7.
    • (2003) Clin Cancer Res , vol.9 , pp. 991-997
    • Li, D.1    Zhu, J.2    Firozi, P.F.3
  • 18
    • 0346217067 scopus 로고    scopus 로고
    • STK15/Aurora-A expression in primary breast tumors is correlated with nuclear grade but not with prognosis
    • Royce ME, Xia W, Sahin AA, et al. STK15/Aurora-A expression in primary breast tumors is correlated with nuclear grade but not with prognosis. Cancer 2004; 100:12-9.
    • (2004) Cancer , vol.100 , pp. 12-19
    • Royce, M.E.1    Xia, W.2    Sahin, A.A.3
  • 19
    • 0035342595 scopus 로고    scopus 로고
    • Association of centrosomal kinase STK15/BTAK mRNA expression with chromosomal instability in human breast cancers
    • Miyoshi Y, Iwao K, Egawa C, Noguchi S. Association of centrosomal kinase STK15/BTAK mRNA expression with chromosomal instability in human breast cancers. Int J Cancer 2001; 92:370-3.
    • (2001) Int J Cancer , vol.92 , pp. 370-373
    • Miyoshi, Y.1    Iwao, K.2    Egawa, C.3    Noguchi, S.4
  • 20
    • 0037019736 scopus 로고    scopus 로고
    • Amplification/overexpression of a mitotic kinase gene in human bladder cancer
    • Sen S, Zhou H, Zhang RD, et al. Amplification/overexpression of a mitotic kinase gene in human bladder cancer. J Natl Cancer Inst 2002; 94:1320-9.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1320-1329
    • Sen, S.1    Zhou, H.2    Zhang, R.D.3
  • 21
    • 0031714080 scopus 로고    scopus 로고
    • Tumor amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
    • Zhou H, Kuang J, Zhong L, Kuo WL, Gray JW, Sahin A, Brinkley BR, Sen S. Tumor amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat Genet 1998; 20:189-93.
    • (1998) Nat Genet , vol.20 , pp. 189-193
    • Zhou, H.1    Kuang, J.2    Zhong, L.3    Kuo, W.L.4    Gray, J.W.5    Sahin, A.6    Brinkley, B.R.7    Sen, S.8
  • 22
    • 38349169905 scopus 로고    scopus 로고
    • Simultaneous Aurora-A/STK15 overexpression and centrosome amplification induce chromosomal instability in tumor cells with a MIN phenotype
    • Lentini L, Amato A, Schillaci T, Di Leonardo A. Simultaneous Aurora-A/STK15 overexpression and centrosome amplification induce chromosomal instability in tumor cells with a MIN phenotype. BMC Cancer 2007; 7:212.
    • (2007) BMC Cancer , vol.7 , pp. 212
    • Lentini, L.1    Amato, A.2    Schillaci, T.3    Di Leonardo, A.4
  • 25
    • 1842647388 scopus 로고    scopus 로고
    • World Health Organization Classification of Tumors
    • Eble JN, Sauter G, Epstein JI, Sesterhenn IA, Eds, Lyon, France: IARC Press
    • Eble JN, Sauter G, Epstein JI, Sesterhenn IA. (Eds.): World Health Organization Classification of Tumors. Pathology and Genetics of Tumors of the Urinary System and Male Genital Organs. Lyon, France: IARC Press 2004; 93.
    • (2004) Pathology and Genetics of Tumors of the Urinary System and Male Genital Organs , pp. 93
  • 27
    • 33746750132 scopus 로고    scopus 로고
    • High-resolution array-based comparative genomic hybridization of medulloblastomas and supratentorial primitive neuroectodermal tumors
    • McCabe MG, Ichimura K, Liu L, Plant K, Backlund LM, Pearson DM, Collins VP. High-resolution array-based comparative genomic hybridization of medulloblastomas and supratentorial primitive neuroectodermal tumors. J Neuropathol Exp Neurol 2006; 65:549-61.
    • (2006) J Neuropathol Exp Neurol , vol.65 , pp. 549-561
    • McCabe, M.G.1    Ichimura, K.2    Liu, L.3    Plant, K.4    Backlund, L.M.5    Pearson, D.M.6    Collins, V.P.7
  • 30
    • 33644867290 scopus 로고    scopus 로고
    • Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays
    • Sanchez-Carbayo M, Socci ND, Lozano J, Saint F, Cordon-Cardo C. Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays. J Clin Oncol 2006; 24:778-89.
    • (2006) J Clin Oncol , vol.24 , pp. 778-789
    • Sanchez-Carbayo, M.1    Socci, N.D.2    Lozano, J.3    Saint, F.4    Cordon-Cardo, C.5
  • 33
    • 0034655991 scopus 로고    scopus 로고
    • Wang Y, Cortez D, Yazdi P, Neff N, Elledge SJ, Qin J. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev 2000; 14:927-39.
    • Wang Y, Cortez D, Yazdi P, Neff N, Elledge SJ, Qin J. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev 2000; 14:927-39.
  • 36
    • 2542418023 scopus 로고    scopus 로고
    • Identifying superficial, muscle-invasive and metastasizing transitional cell carcinoma of the bladder: Use of cDNA array analysis of gene expression profiles
    • Modlich O, Prisack HB, Pitschke G, Ramp U, Ackermann R, Bojar H, Vogeli TA, Grimm MO. Identifying superficial, muscle-invasive and metastasizing transitional cell carcinoma of the bladder: use of cDNA array analysis of gene expression profiles. Clin Cancer Res 2004; 10:3410-215.
    • (2004) Clin Cancer Res , vol.10 , pp. 3410-4215
    • Modlich, O.1    Prisack, H.B.2    Pitschke, G.3    Ramp, U.4    Ackermann, R.5    Bojar, H.6    Vogeli, T.A.7    Grimm, M.O.8
  • 39
    • 35148812601 scopus 로고    scopus 로고
    • Complex engagement of DNA damage response pathways in human cancer and in lung tumor progression
    • Nuciforo PG, Luise C, Capra M, Pelosi G, d'Adda di Fagagna F. Complex engagement of DNA damage response pathways in human cancer and in lung tumor progression. Carcinogenesis 2007; 28:2082-8.
    • (2007) Carcinogenesis , vol.28 , pp. 2082-2088
    • Nuciforo, P.G.1    Luise, C.2    Capra, M.3    Pelosi, G.4    d'Adda di Fagagna, F.5
  • 41
    • 0030864009 scopus 로고    scopus 로고
    • Chen Y, Riley DJ, Chen PL, Lee WH. HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis. Mol Cell Biol 1997; 17:6049-56.
    • Chen Y, Riley DJ, Chen PL, Lee WH. HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis. Mol Cell Biol 1997; 17:6049-56.
  • 42
    • 0034799722 scopus 로고    scopus 로고
    • The ZW10 and rough deal checkpoint proteins function together in a large, evolutionarily conserved complex targeted to the kinetochore
    • Scaerou F, Starr DA, Piano F, Papoulas O, Karess RE, Goldberg ML. The ZW10 and rough deal checkpoint proteins function together in a large, evolutionarily conserved complex targeted to the kinetochore. J Cell Sci 2001; 114:3103-14.
    • (2001) J Cell Sci , vol.114 , pp. 3103-3114
    • Scaerou, F.1    Starr, D.A.2    Piano, F.3    Papoulas, O.4    Karess, R.E.5    Goldberg, M.L.6
  • 43
    • 33646409883 scopus 로고    scopus 로고
    • BRCA1 downregulation leads to premature inactivation of spindle checkpoint and confers paclitaxel resistance
    • Chabalier C, Lamare C, Racca C, Privat M, Valette A, Larminat F. BRCA1 downregulation leads to premature inactivation of spindle checkpoint and confers paclitaxel resistance. Cell Cycle 2006; 5:1001-7.
    • (2006) Cell Cycle , vol.5 , pp. 1001-1007
    • Chabalier, C.1    Lamare, C.2    Racca, C.3    Privat, M.4    Valette, A.5    Larminat, F.6
  • 44
    • 0030840402 scopus 로고    scopus 로고
    • HEC binds to the seventh regulatory subunit of the 26 S pro-teasome and modulates the proteolysis of mitotic cyclins
    • Chen Y, Sharp ZD, Lee WH. HEC binds to the seventh regulatory subunit of the 26 S pro-teasome and modulates the proteolysis of mitotic cyclins. J Biol Chem 1997; 272:24081-7.
    • (1997) J Biol Chem , vol.272 , pp. 24081-24087
    • Chen, Y.1    Sharp, Z.D.2    Lee, W.H.3
  • 45
    • 33646851446 scopus 로고    scopus 로고
    • Spindle checkpoint function requires Mad2-dependent Cdc20 binding to the Mad3 homology domain of BubR1
    • Davenport J, Harris LD, Goorha R. Spindle checkpoint function requires Mad2-dependent Cdc20 binding to the Mad3 homology domain of BubR1. Exp Cell Res 2006; 312:1831-42.
    • (2006) Exp Cell Res , vol.312 , pp. 1831-1842
    • Davenport, J.1    Harris, L.D.2    Goorha, R.3
  • 47
    • 0030876766 scopus 로고    scopus 로고
    • A novel mammalian, mitotic spindle-associated kinase is related to yeast and fly chromosome segregation regulators
    • Gopalan G, Chan CS, Donovan PJ. A novel mammalian, mitotic spindle-associated kinase is related to yeast and fly chromosome segregation regulators. J Cell Biol 1997; 138:643-56.
    • (1997) J Cell Biol , vol.138 , pp. 643-656
    • Gopalan, G.1    Chan, C.S.2    Donovan, P.J.3
  • 50
    • 0037586498 scopus 로고    scopus 로고
    • AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol
    • Anand S, Penrhyn-Lowe S, Venkitaraman AR. AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol. Cancer Cell 2003; 3:51-62.
    • (2003) Cancer Cell , vol.3 , pp. 51-62
    • Anand, S.1    Penrhyn-Lowe, S.2    Venkitaraman, A.R.3
  • 51
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical Bayes methods for assessing differential expression in microarray experiments
    • Smyth GK. Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Statistical Applications in Genetics and Molecular Biology 2004; 3.
    • (2004) Statistical Applications in Genetics and Molecular Biology , pp. 3
    • Smyth, G.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.