Secretion of tumor necrosis factor-α shows a strong relationship to insulin-stimulated glucose transport in human adipose tissue

Diabetes

Volumn 49, Issue 5, 2000, Pages 688-692

  Löfgren, Patrik ^a   Van Harmelen, Vanessa ^a   Reynisdottir, Signy ^a   Näslund, Erik ^b   Rydén, Mikael ^a   Rössner, Stephan ^a   Arner, Peter ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b DANDERYD HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

ADIPOSE TISSUE; ADULT; ARTICLE; CLINICAL ARTICLE; DIABETES MELLITUS; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; HUMAN; HUMAN TISSUE; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL;

EID: 0342265155     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.49.5.688     Document Type: Article

References (36)

1. Kissebah AH, Krakower GR, Sonnenberg GE, Hennes MI: Clinical manifestations of the metabolic syndrome. In Handbook of Obesity. Bray GA, Bouchard C, James WP, Eds. New York, Marcel Dekker, 1998, p. 601-636
2. Hotamisligil GS, Spiegelman BM: Tumor necrosis factor alpha: a key component of the obesity-diabetes link. Diabetes 43:1271-1278, 1994
3. Hotamisligil GS, Arner P, Caro, JF, Atkinson RL, Spiegelman BM: Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance. J Clin Invest 95:2409-2415, 1995
4. Kern PA, Saghizadeh M, Ong JM, Bosch RJ, Deem R, Simsolo RB: The expression of tumor necrosis factor in human adipose tissue: regulation by obesity, weight loss and relationship to lipoprotein lipase. J Clin Invest 95:2111-2119, 1995
5. Hotamisligil GS, Shargill NS, Spiegelman BM: Adipose expression of tumor necrosis factor alpha: direct role in obesity-linked insulin resistance. Science 259:87-91, 1993
6. Cheung AT, Ree D, Kolls JK, Fuselier J, Coy DH, Bryer-Ash M: An in vivo model for elucidation of the mechanism of tumor necrosis factor-α (TNF-α) induced insulin resistance: evidence for differential regulation of insulin signaling by TNF-α. Endocrinology 139:4928-4935, 1998
7. Uysal KT, Wiesbrock SM, Marino MW, Hotamisligl GS: Protection from obesity induced insulin resistance in mice lacking TNF-α function. Nature 389: 610-614, 1997
8. Ventre J, Doebber T, Wu M, MacNaul K, Stevens K, Pasparakis M, Kollias G, Moller DE: Targeted disruption of the tumor necrosis factor-α gene. Diabetes 46:1526-1531, 1997
9. Schreyer SA, Chua SC Jr, LeBoef RC: Obesity and diabetes in TNF alpha receptor-deficient mice. J Clin Invest 102:402-411, 1998
10. Mohamed-Ali V, Goodrick S, Rawesh A, Katz DR, Miles JM, Klein S, Yudkin JS, Coppack SW: Subcutaneous adipose tissue releases interleukin-6 but not tumor necrosis factor alpha, in vivo. J Clin Endocrinol Metab 82:4196-4200, 1997
11. Zinman B, Hanley AJG, Harris SB, Kwan J, Fantus IG. Circulating tumor necrosis factor-α concentrations in native Canadian population with high rates of type 2 diabetes mellitus. J Clin Endocrinol Metab 84:272-278, 1999
12. Desfaits A-C, Serri O, Renier G: Normalization of plasma lipid peroxides, monocyte adhesion, and tumor necrosis factor-α production in NIDDM patients after gliclazide treatment. Diabetes Care 21:487-493, 1998
13. Dandona M, Weinstock R, Thusu K, Abdel-Rahman E, Aljada A, Wadden T: Tumor necrosis factor-α in sera of obese patients: fall with weight loss. J Clin Endocrinol Metab 83:2907-2910, 1998
14. Katsuki A, Sumida Y, Murashima S, Murata K, Takarada Y, Ito K, Fujii M, Tsuchihashi K, Goto H, Nakatani K, Yano Y: Serum levels of tumor necrosis factor-α are increased in obese patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 83:859-862, 1998
15. Nilsson J, Jovinge S, Niemann A, Reneland R, Lithell H: Relation between plasma tumor necrosis factor-α and insulin sensitivity in elderly men with non-insulin-dependent diabetes mellitus. Arterioscler Thromb Vasc Biol 18:1199-1202, 1998
16. Winkler G, Salamon F, Harmos G, Salamon D, Speer G, Szekeres O, Hajos P, Kevacs M, Simon K, Cseh K: Elevalod serum tumor necrosis factor-α concentrations and bioactivity in type 2 diabetics and patients with android type obesity. Diabetes Res Clin Pract 42:169-174, 1998
17. Yudkin JS, Stehouwer CDA, Emeis JJ, Coppack SW: C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue? Arterioscler Thromb Vasc Biol 19:972-978, 1999
18. Paolisso G, Rizzo MR, Mazziotti G, Tagliamonte MR, Gambardella A, Rotondi M, Carella C, Giugliano D, Varicchio M, D'Onofrio F: Advancing age and insulin resistance: role of plasma tumor necrosis factor-α. Am J Physiol 275:E294-E299, 1998
19. Kellerer M, Rett K, Renn W, Groop L, Häring HU: Circulating TNF-alpha and leptin levels in offspring of NIDDM patients do not correlate to individual insulin sensitivity. Horm Metab Res 28:737-743, 1996
20. Ofei F, Hurel S, Newkirk J, Sopwith M, Taylor R: Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM. Diabetes 45:881-885, 1996
21. Saghizadeh M, Ong JM, Garvey WT, Henry RR, Kern PA: The expression of TNF-alpha by human muscle: relationship to insulin resistance. J Clin Invest 97:1111-1116, 1996
22. Eriksson P, Reynisdottir S, Lönnqvist F, Stemme V. Hamsten A, Arner P: Adipose tissue secretion of plasminogen activator inhibitor-1 in non-obese and obese individuals. Diabetologia 41:65-71, 1998
23. Kolaczynski SW, Morales LM, Moore JH Jr, Considine RV, Pietrzkowski Z, Noto PF, Colberg J, Caro JF: A new technique for biopsy of human abdominal fat under local anaesthesia with lidocaine. Int J Obes 3:161-166, 1994
24. Reynisdottir S, Eleborg L, van Harmelen V, Strömmer L, Arner P: Lipolysis in human fat cells obtained under local and general anesthesia. Int J Obes 21:78-82, 1997
25. Rodbell M: Metabolism of isolated fat cells: effects of hormones on glucose metabolism and lipolysis. J Biol Chem 239:375-380, 1964
26. Hirsh J, Gallian E: Methods for determination of adipose cell size and cell number in man and animals. J Lipid Res 9:110-119, 1968
27. Whitesell RR, Glieman J: Kinetic parameters of transport of 3-O-methyl glucose in adipocytes. J Biol Chem 254:5276-5283, 1979
28. Moody AJ, Stan MA, Stan M, Glieman J: A simple free fat cell bioassay for insulin. Horm Metab Res 6:12-16, 1974
29. Arner P, Engfeldt P: Fasting mediated alteration studies of insulin action on lipolysis and lipogenesis in obese women. Am J Physiol 253:193-201, 1987
30. Nordenström J, Sonnenfeld T, Arner P: Characterization of insulin resistance after surgery. Surgery 1:28-35, 1989
31. Bolinder J, Östman J, Arner P: Post receptor defects causing insulin resistance in normoinsulinemic non-insulin dependent diabetes mellitus. Diabetes 31:911-916, 1982
32. Kenakin T: The classification of drugs and drug receptors in isolated tissue. Pharmacol Rev 36:165-222, 1984
33. Kahn CR: Insulin resistance, insulin insensitivity, and insulin unresponsiveness: a necessary distinction. Metabolism 27:1893-1902, 1978
34. 1 protein concentrations. J Biol Chem 274:6770-6775, 1999
35. Hauner H, Petruschke T, Russ M, Eckel J: Effects of tumor necrosis factor alpha on glucose transport and lipid metabolism of newly differentiated human fat cells in cell culture. Diabetologia 38:764-771, 1995
36. Mohamed-Ali V, Pinkney JH, Coppack SW: Adipose tissue as an endocrine and paracrine organ. Int J Obes Relat Metab Disord 22:1145-1158, 1998