Rosiglitazone produces insulin sensitisation by increasing expression of the insulin receptor and its tyrosine kinase activity in brown adipocytes

Diabetologia

Volumn 46, Issue 12, 2003, Pages 1618-1628

  Hernandez, R ^a   Teruel, T ^a   Lorenzo, M ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Akt; Brown adipocytes; Glucose uptake; GLUT4 translocation; Insulin; Insulin receptor; Insulin receptor substrate 2; Protein tyrosine phosphatase 1B; Rosiglitazone

Indexed keywords

GLUCOSE TRANSPORTER 4; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE C ZETA; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE 1B; ROSIGLITAZONE; SERINE;

ANIMAL CELL; ARTICLE; BETA CHAIN; BROWN ADIPOSE TISSUE; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; CYTOLYSIS; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; ENZYME ACTIVITY; FETUS; GENE EXPRESSION; GLUCOSE TRANSPORT; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INSULIN SENSITIVITY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ADIPOCYTES; ADIPOSE TISSUE, BROWN; ANIMALS; BIOLOGICAL TRANSPORT; DEOXYGLUCOSE; FETUS; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; HYPOGLYCEMIC AGENTS; INSULIN; MITOGEN-ACTIVATED PROTEIN KINASES; MONOSACCHARIDE TRANSPORT PROTEINS; MUSCLE PROTEINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN TRANSPORT; RATS; RATS, WISTAR; RECEPTOR, INSULIN; THIAZOLIDINEDIONES;

EID: 0348107407     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-003-1236-z     Document Type: Article

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