-
2
-
-
56249105151
-
-
Supuran C.T., Scozzafava A., and Conway J. (Eds), CRC Press, Boca Raton (FL), USA and references cited therein
-
In: Supuran C.T., Scozzafava A., and Conway J. (Eds). Carbonic Anhydrase-Its Inhibitors and Activators (2004), CRC Press, Boca Raton (FL), USA 1-376 and references cited therein
-
(2004)
Carbonic Anhydrase-Its Inhibitors and Activators
, pp. 1-376
-
-
-
4
-
-
42549148009
-
-
Winum J.Y., Rami M., Scozzafava A., Montero J.L., and Supuran C. Med. Res. Rev. 28 (2008) 445
-
(2008)
Med. Res. Rev.
, vol.28
, pp. 445
-
-
Winum, J.Y.1
Rami, M.2
Scozzafava, A.3
Montero, J.L.4
Supuran, C.5
-
5
-
-
0029120989
-
-
Lynch C.J., Fox H., Hazen S.A., Stanley B.A., Dodgson S.J., and Lanoue K.F. Biochem. J. 310 (1995) 197
-
(1995)
Biochem. J.
, vol.310
, pp. 197
-
-
Lynch, C.J.1
Fox, H.2
Hazen, S.A.3
Stanley, B.A.4
Dodgson, S.J.5
Lanoue, K.F.6
-
6
-
-
0029933488
-
-
Hazen S.A., Waheed A., Sly W.S., Lanoue K.F., and Lynch C.J. FASEB J. 10 (1996) 481
-
(1996)
FASEB J.
, vol.10
, pp. 481
-
-
Hazen, S.A.1
Waheed, A.2
Sly, W.S.3
Lanoue, K.F.4
Lynch, C.J.5
-
7
-
-
0034576649
-
-
Picard F., Deshaies Y., Lalonde J., Samson P., and Richard D. Obesity Res. 8 (2000) 656
-
(2000)
Obesity Res.
, vol.8
, pp. 656
-
-
Picard, F.1
Deshaies, Y.2
Lalonde, J.3
Samson, P.4
Richard, D.5
-
12
-
-
1242318777
-
-
Vullo D., Franchi M., Gallori E., Antel J., Scozzafava A., and Supuran C.T. J. Med. Chem. 47 (2004) 1272
-
(2004)
J. Med. Chem.
, vol.47
, pp. 1272
-
-
Vullo, D.1
Franchi, M.2
Gallori, E.3
Antel, J.4
Scozzafava, A.5
Supuran, C.T.6
-
13
-
-
5144220555
-
-
Innocenti A., Antel J., Wurl M., Scozzafava A., and Supuran C.T. Bioorg. Med. Chem. Lett. 14 (2004) 5703
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 5703
-
-
Innocenti, A.1
Antel, J.2
Wurl, M.3
Scozzafava, A.4
Supuran, C.T.5
-
14
-
-
17144375722
-
-
De Simone G., Di Fiore A., Menchise V., Pedone C., Antel J., Casini A., Scozzafava A., Wurl M., and Supuran C.T. Bioorg. Med. Chem. Lett. 15 (2005) 2315
-
(2005)
Bioorg. Med. Chem. Lett.
, vol.15
, pp. 2315
-
-
De Simone, G.1
Di Fiore, A.2
Menchise, V.3
Pedone, C.4
Antel, J.5
Casini, A.6
Scozzafava, A.7
Wurl, M.8
Supuran, C.T.9
-
15
-
-
26844469638
-
-
Cecchi A., Taylor S.D., Liu Y., Hill B., Vullo D., Scozzafava A., and Supuran C.T. Bioorg. Med. Chem. Lett. 15 (2005) 5192
-
(2005)
Bioorg. Med. Chem. Lett.
, vol.15
, pp. 5192
-
-
Cecchi, A.1
Taylor, S.D.2
Liu, Y.3
Hill, B.4
Vullo, D.5
Scozzafava, A.6
Supuran, C.T.7
-
16
-
-
28144452672
-
-
Nishimori I., Vullo D., Innocenti A., Scozzafava A., Mastrolorenzo A., and Supuran C.T. J. Med. Chem. 48 (2005) 7860
-
(2005)
J. Med. Chem.
, vol.48
, pp. 7860
-
-
Nishimori, I.1
Vullo, D.2
Innocenti, A.3
Scozzafava, A.4
Mastrolorenzo, A.5
Supuran, C.T.6
-
17
-
-
53249121381
-
-
Güzel O., Innocenti A., Scozzafava A., Salman A., Parkkila S., Hilvo M., and Supuran C.T. Bioorg. Med. Chem. 16 (2008) 9113
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 9113
-
-
Güzel, O.1
Innocenti, A.2
Scozzafava, A.3
Salman, A.4
Parkkila, S.5
Hilvo, M.6
Supuran, C.T.7
-
18
-
-
48649096568
-
-
Poulsen S.-A., Wilkinson B.L., Innocenti A., Vullo D., and Supuran C.T. Bioorg. Med. Chem. Lett. 18 (2008) 4624
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 4624
-
-
Poulsen, S.-A.1
Wilkinson, B.L.2
Innocenti, A.3
Vullo, D.4
Supuran, C.T.5
-
23
-
-
0344193512
-
-
Casini A., Antel J., Abbate F., Scozzafava A., David S., Waldeck H., Schäfer S., and Supuran C.T. Bioorg. Med. Chem. Lett. 13 (2003) 841
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 841
-
-
Casini, A.1
Antel, J.2
Abbate, F.3
Scozzafava, A.4
David, S.5
Waldeck, H.6
Schäfer, S.7
Supuran, C.T.8
-
24
-
-
0037430430
-
-
Casini A., Winum J.-Y., Montero J.-L., Scozzafava A., and Supuran C.T. Bioorg. Med. Chem. Lett. 13 (2003) 837
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 837
-
-
Casini, A.1
Winum, J.-Y.2
Montero, J.-L.3
Scozzafava, A.4
Supuran, C.T.5
-
25
-
-
0346252639
-
-
Abbate F., Winum J.-Y., Potter B.V.L., Casini A., Montero J.-L., Scozzafava A., and Supuran C.T. Bioorg. Med. Chem. Lett. 14 (2004) 231
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 231
-
-
Abbate, F.1
Winum, J.-Y.2
Potter, B.V.L.3
Casini, A.4
Montero, J.-L.5
Scozzafava, A.6
Supuran, C.T.7
-
26
-
-
33845353402
-
-
Winum J.Y., Temperini C., El Cheikh K., Innocenti A., Vullo D., Ciattini S., Montero J.L., Scozzafava A., and Supuran C.T. J. Med. Chem. 49 (2006) 7024
-
(2006)
J. Med. Chem.
, vol.49
, pp. 7024
-
-
Winum, J.Y.1
Temperini, C.2
El Cheikh, K.3
Innocenti, A.4
Vullo, D.5
Ciattini, S.6
Montero, J.L.7
Scozzafava, A.8
Supuran, C.T.9
-
27
-
-
56249128663
-
-
note
-
6) δ 7.14 (s, 2H), 3.5 (s, 3H), 3.16 (s, 1H).
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-
-
-
28
-
-
0035850282
-
-
Winum J.Y., Toupet L., Barragan V., Dewynter G., and Montero J.L. Org. Lett. 3 (2001) 2241
-
(2001)
Org. Lett.
, vol.3
, pp. 2241
-
-
Winum, J.Y.1
Toupet, L.2
Barragan, V.3
Dewynter, G.4
Montero, J.L.5
-
30
-
-
56249115268
-
-
Di Fiore, A.; Monti, S. M.; Hilvo, M.; Parkkila, S.; Romano, V.; Scaloni, A.; Pedone, C.; Scozzafava, A.; Supuran, C.T.; De Simone, G. Proteins 2008, in press.
-
Di Fiore, A.; Monti, S. M.; Hilvo, M.; Parkkila, S.; Romano, V.; Scaloni, A.; Pedone, C.; Scozzafava, A.; Supuran, C.T.; De Simone, G. Proteins 2008, in press.
-
-
-
-
31
-
-
33750703618
-
-
Menchise V., De Simone G., Di Fiore A., Scozzafava A., and Supuran C.T. Bioorg. Med. Chem. Lett. 16 (2006) 6204
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 6204
-
-
Menchise, V.1
De Simone, G.2
Di Fiore, A.3
Scozzafava, A.4
Supuran, C.T.5
-
32
-
-
0031776867
-
-
Supuran C.T., Mincione F., Scozzafava A., Briganti F., Mincione G., and Ilies M.A. Eur. J. Med. Chem. 33 (1998) 247
-
(1998)
Eur. J. Med. Chem.
, vol.33
, pp. 247
-
-
Supuran, C.T.1
Mincione, F.2
Scozzafava, A.3
Briganti, F.4
Mincione, G.5
Ilies, M.A.6
-
33
-
-
37549037851
-
-
Güzel O., Temperini C., Innocenti A., Scozzafava A., Salman A., and Supuran CT. Bioorg. Med. Chem. Lett. 18 (2008) 152
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 152
-
-
Güzel, O.1
Temperini, C.2
Innocenti, A.3
Scozzafava, A.4
Salman, A.5
Supuran, CT.6
-
34
-
-
0034645612
-
-
Kim C.Y., Chang J.S., Doyon J.B., Baird T.T., Fierke C.A., Jain A., and Christianson D.W. J. Am. Chem. Soc. 122 (2000) 12125
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 12125
-
-
Kim, C.Y.1
Chang, J.S.2
Doyon, J.B.3
Baird, T.T.4
Fierke, C.A.5
Jain, A.6
Christianson, D.W.7
-
35
-
-
4544324380
-
-
Supuran C.T., Scozzafava A., and Conway J. (Eds), CRC Press, Boca Raton
-
Antel J., Weber A., Sotriffer C.A., and Klebe G. In: Supuran C.T., Scozzafava A., and Conway J. (Eds). Carbonic Anhydrase-Its Inhibitors and Activators (2004), CRC Press, Boca Raton 45-65
-
(2004)
Carbonic Anhydrase-Its Inhibitors and Activators
, pp. 45-65
-
-
Antel, J.1
Weber, A.2
Sotriffer, C.A.3
Klebe, G.4
-
36
-
-
42149143745
-
-
Krishnamurthy V.M., Kaufman G.K., Urbach A.R., Gitlin I., Gudiksen K.L., Weibel D.B., and Whitesides G.M. Chem. Rev. 108 (2008) 946
-
(2008)
Chem. Rev.
, vol.108
, pp. 946
-
-
Krishnamurthy, V.M.1
Kaufman, G.K.2
Urbach, A.R.3
Gitlin, I.4
Gudiksen, K.L.5
Weibel, D.B.6
Whitesides, G.M.7
-
37
-
-
0027062907
-
-
Supuran C.T., Manole G., Dinculescu A., Schiketanz A., Gheorghiu M.D., Puscas I., and Balaban A.T. J. Pharm. Sci. 81 (1992) 716
-
(1992)
J. Pharm. Sci.
, vol.81
, pp. 716
-
-
Supuran, C.T.1
Manole, G.2
Dinculescu, A.3
Schiketanz, A.4
Gheorghiu, M.D.5
Puscas, I.6
Balaban, A.T.7
-
38
-
-
15044351878
-
-
Di Fiore A., De Simone G., Menchise V., Pedone C., Casini A., Scozzafava A., and Supuran C.T. Bioorg. Med. Chem. Lett. 15 (2005) 1937
-
(2005)
Bioorg. Med. Chem. Lett.
, vol.15
, pp. 1937
-
-
Di Fiore, A.1
De Simone, G.2
Menchise, V.3
Pedone, C.4
Casini, A.5
Scozzafava, A.6
Supuran, C.T.7
-
39
-
-
0034649604
-
-
Casini A., Scozzafava A., Mincione F., Menabuoni L., Ilies M.A., and Supuran C.T. J. Med. Chem. 43 (2000) 4884
-
(2000)
J. Med. Chem.
, vol.43
, pp. 4884
-
-
Casini, A.1
Scozzafava, A.2
Mincione, F.3
Menabuoni, L.4
Ilies, M.A.5
Supuran, C.T.6
-
40
-
-
24744467784
-
-
Menchise V., De Simone G., Alterio V., Di Fiore A., Pedone C., Scozzafava A., and Supuran C.T. J. Med. Chem. 48 (2005) 5721
-
(2005)
J. Med. Chem.
, vol.48
, pp. 5721
-
-
Menchise, V.1
De Simone, G.2
Alterio, V.3
Di Fiore, A.4
Pedone, C.5
Scozzafava, A.6
Supuran, C.T.7
-
41
-
-
33745644458
-
-
Alterio V., Vitale R.M., Monti S.M., Pedone C., Scozzafava A., Cecchi A., De Simone G., and Supuran C.T. J. Am. Chem. Soc. 128 (2006) 8329
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 8329
-
-
Alterio, V.1
Vitale, R.M.2
Monti, S.M.3
Pedone, C.4
Scozzafava, A.5
Cecchi, A.6
De Simone, G.7
Supuran, C.T.8
-
42
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0015239422
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note
-
2 concentrations ranged from 1.7 to 17 mM for the determination of the kinetic parameters and inhibition constants. For each inhibitor at least six traces of the initial 5-10% of the reaction have been used for determining the initial velocity. The uncatalyzed rates were determined in the same manner and subtracted from the total observed rates. Stock solutions of inhibitor (10 mM) were prepared in distilled-deionized water with 10-20% (v/v) DMSO (which is not inhibitory at these concentrations) and dilutions up to 0.1 nM were done thereafter with distilled-deionized water. Inhibitor and enzyme solutions were preincubated together for 15 min at room temperature prior to assay, in order to allow for the formation of the E-I complex. The inhibition constants were obtained by non-linear least-squares methods using PRISM 3, and represent the mean from at least three different determinations.
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