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Volumn 28, Issue 44, 2008, Pages 11409-11420

Requirement of 3-phosphoinositide-dependent protein kinase-1 for BDNF-mediated neuronal survival

Author keywords

Akt; Development; MAP kinase; Neurotrophins; p90RSK; Protein kinase B; Survival; TrkB

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; S6 KINASE; 3 PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE; 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE;

EID: 56149117611     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2135-08.2008     Document Type: Article
Times cited : (27)

References (49)
  • 1
    • 0036178441 scopus 로고    scopus 로고
    • Molecular psychology: Roles for the ERK MAP kinase cascade in memory
    • Adams JP, Sweatt JD (2002) Molecular psychology: roles for the ERK MAP kinase cascade in memory. Annu Rev Pharmacol Toxicol 42:135-163.
    • (2002) Annu Rev Pharmacol Toxicol , vol.42 , pp. 135-163
    • Adams, J.P.1    Sweatt, J.D.2
  • 2
    • 0030995057 scopus 로고    scopus 로고
    • TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death
    • Alcántara S, Frisén J, del Río JA, Soriano E, Barbacid M, Silos-Santiago I (1997) TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death. J Neurosci 17:3623-3633.
    • (1997) J Neurosci , vol.17 , pp. 3623-3633
    • Alcántara, S.1    Frisén, J.2    del Río, J.A.3    Soriano, E.4    Barbacid, M.5    Silos-Santiago, I.6
  • 4
    • 0032698075 scopus 로고    scopus 로고
    • Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms
    • Bonni A, Brunet A, West AE, Datta SR, Takasu MA, Greenberg ME (1999) Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 286:1358-1362.
    • (1999) Science , vol.286 , pp. 1358-1362
    • Bonni, A.1    Brunet, A.2    West, A.E.3    Datta, S.R.4    Takasu, M.A.5    Greenberg, M.E.6
  • 5
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp TR, Bernards R, Agami R (2002) A system for stable expression of short interfering RNAs in mammalian cells. Science 296:550-553.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 6
    • 33747869352 scopus 로고    scopus 로고
    • Adaptive roles of programmed cell death during nervous system development
    • Buss RR, Sun W, Oppenheim RW (2006) Adaptive roles of programmed cell death during nervous system development. Annu Rev Neurosci 29:1-35.
    • (2006) Annu Rev Neurosci , vol.29 , pp. 1-35
    • Buss, R.R.1    Sun, W.2    Oppenheim, R.W.3
  • 7
    • 0024543825 scopus 로고
    • Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element
    • Cherrington JM, Mocarski ES (1989) Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element. J Virol 63:1435-1440.
    • (1989) J Virol , vol.63 , pp. 1435-1440
    • Cherrington, J.M.1    Mocarski, E.S.2
  • 8
    • 0007588936 scopus 로고    scopus 로고
    • Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway
    • Cho KS, Lee JH, Kim S, Kim D, Koh H, Lee J, Kim C, Kim J, Chung J (2001) Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway. Proc Natl Acad Sci U S A 98:6144-6149.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 6144-6149
    • Cho, K.S.1    Lee, J.H.2    Kim, S.3    Kim, D.4    Koh, H.5    Lee, J.6    Kim, C.7    Kim, J.8    Chung, J.9
  • 9
    • 33847042741 scopus 로고    scopus 로고
    • A clickable inhibitor reveals context-dependent autoactivation of p90 RSK. Nat
    • Cohen MS, Hadjivassiliou H, Taunton J (2007) A clickable inhibitor reveals context-dependent autoactivation of p90 RSK. Nat Chem Biol 3:156 -160.
    • (2007) Chem Biol , vol.3 , pp. 156-160
    • Cohen, M.S.1    Hadjivassiliou, H.2    Taunton, J.3
  • 10
    • 0042967831 scopus 로고    scopus 로고
    • In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation
    • Collins BJ, Deak M, Arthur JS, Armit LJ, Alessi DR (2003) In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation. EMBO J 22:4202-4211.
    • (2003) EMBO J , vol.22 , pp. 4202-4211
    • Collins, B.J.1    Deak, M.2    Arthur, J.S.3    Armit, L.J.4    Alessi, D.R.5
  • 11
    • 27944482145 scopus 로고    scopus 로고
    • In vivo role of the phosphate groove of PDK1 defined by knockin mutation
    • Collins BJ, Deak M, Murray-Tait V, Storey KG, Alessi DR (2005) In vivo role of the phosphate groove of PDK1 defined by knockin mutation. J Cell Sci 118:5023-5034.
    • (2005) J Cell Sci , vol.118 , pp. 5023-5034
    • Collins, B.J.1    Deak, M.2    Murray-Tait, V.3    Storey, K.G.4    Alessi, D.R.5
  • 12
  • 13
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME (1997) Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91:231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 14
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta SR, Brunet A, Greenberg ME (1999) Cellular survival: a play in three Akts. Genes Dev 13:2905-2927.
    • (1999) Genes Dev , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 15
    • 1842333237 scopus 로고    scopus 로고
    • del Peso L, González-García M, Page C, Herrera R, Nuñez G (1997) Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 278:687-689.
    • del Peso L, González-García M, Page C, Herrera R, Nuñez G (1997) Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 278:687-689.
  • 16
    • 22744449792 scopus 로고    scopus 로고
    • Spatially separate docking sites on ERK2 regulate distinct signaling events in vivo
    • Dimitri CA, Dowdle W, MacKeigan JP, Blenis J, Murphy LO (2005) Spatially separate docking sites on ERK2 regulate distinct signaling events in vivo. Curr Biol 15:1319-1324.
    • (2005) Curr Biol , vol.15 , pp. 1319-1324
    • Dimitri, C.A.1    Dowdle, W.2    MacKeigan, J.P.3    Blenis, J.4    Murphy, L.O.5
  • 17
    • 0031053586 scopus 로고    scopus 로고
    • Dudek H, Datta SR, Franke TF, Birnbaum MJ, Yao R, Cooper GM, Segal RA, Kaplan DR, Greenberg ME (1997) Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 275:661-665.
    • Dudek H, Datta SR, Franke TF, Birnbaum MJ, Yao R, Cooper GM, Segal RA, Kaplan DR, Greenberg ME (1997) Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 275:661-665.
  • 18
    • 0034676303 scopus 로고    scopus 로고
    • Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival
    • Flynn P, Wongdagger M, Zavar M, Dean NM, Stokoe D (2000) Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival. Curr Biol 10:1439-1442.
    • (2000) Curr Biol , vol.10 , pp. 1439-1442
    • Flynn, P.1    Wongdagger, M.2    Zavar, M.3    Dean, N.M.4    Stokoe, D.5
  • 19
    • 33644877643 scopus 로고    scopus 로고
    • NMDA neuroprotection against a phosphatidylinositol-3 kinase inhibitor, LY294002 by NR2B-mediated suppression of glycogen synthase kinase-3beta-induced apoptosis
    • Habas A, Kharebava G, Szatmari E, Hetman M (2006) NMDA neuroprotection against a phosphatidylinositol-3 kinase inhibitor, LY294002 by NR2B-mediated suppression of glycogen synthase kinase-3beta-induced apoptosis. J Neurochem 96:335-348.
    • (2006) J Neurochem , vol.96 , pp. 335-348
    • Habas, A.1    Kharebava, G.2    Szatmari, E.3    Hetman, M.4
  • 20
    • 33748320817 scopus 로고    scopus 로고
    • RSK and MSK in MAP kinase signalling
    • Hauge C, Frödin M (2006) RSK and MSK in MAP kinase signalling. J Cell Sci 119:3021-3023.
    • (2006) J Cell Sci , vol.119 , pp. 3021-3023
    • Hauge, C.1    Frödin, M.2
  • 22
    • 0034175688 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal
    • Hetman M, Cavanaugh JE, Kimelman D, Xia Z (2000) Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal. J Neurosci 20:2567-2574.
    • (2000) J Neurosci , vol.20 , pp. 2567-2574
    • Hetman, M.1    Cavanaugh, J.E.2    Kimelman, D.3    Xia, Z.4
  • 23
    • 0037147327 scopus 로고    scopus 로고
    • ERK1/2 antagonizes glycogen synthase kinase-3beta -induced apoptosis in cortical neurons
    • Hetman M, Hsuan SL, Habas A, Higgins MJ, Xia Z (2002) ERK1/2 antagonizes glycogen synthase kinase-3beta -induced apoptosis in cortical neurons. J Biol Chem 277:49577-49584.
    • (2002) J Biol Chem , vol.277 , pp. 49577-49584
    • Hetman, M.1    Hsuan, S.L.2    Habas, A.3    Higgins, M.J.4    Xia, Z.5
  • 24
    • 0033578776 scopus 로고    scopus 로고
    • 90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1
    • Jensen CJ, Buch MB, Krag TO, Hemmings BA, Gammeltoft S, Frödin M (1999) 90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1. J Biol Chem 274:27168-27176.
    • (1999) J Biol Chem , vol.274 , pp. 27168-27176
    • Jensen, C.J.1    Buch, M.B.2    Krag, T.O.3    Hemmings, B.A.4    Gammeltoft, S.5    Frödin, M.6
  • 25
    • 33749162839 scopus 로고    scopus 로고
    • Role of megakaryoblastic acute leukemia-1 in ERK1/2-dependent stimulation of serum response factor-driven transcription by BDNF or increased synaptic activity
    • Kalita K, Kharebava G, Zheng JJ, Hetman M (2006) Role of megakaryoblastic acute leukemia-1 in ERK1/2-dependent stimulation of serum response factor-driven transcription by BDNF or increased synaptic activity. J Neurosci 26:10020-10032.
    • (2006) J Neurosci , vol.26 , pp. 10020-10032
    • Kalita, K.1    Kharebava, G.2    Zheng, J.J.3    Hetman, M.4
  • 26
    • 0034044227 scopus 로고    scopus 로고
    • Neurotrophin signal transduction in the nervous system
    • Kaplan DR, Miller FD (2000) Neurotrophin signal transduction in the nervous system. Curr Opin Neurobiol 10:381-391.
    • (2000) Curr Opin Neurobiol , vol.10 , pp. 381-391
    • Kaplan, D.R.1    Miller, F.D.2
  • 29
    • 33747610198 scopus 로고    scopus 로고
    • Differential roles of phosphoinositide-dependent protein kinase-1 and akt1 expression and phosphorylation in breast cancer cell resistance to Paclitaxel, Doxorubicin, and gemcitabine
    • Liang K, Lu Y, Li X, Zeng X, Glazer RI, Mills GB, Fan Z (2006) Differential roles of phosphoinositide-dependent protein kinase-1 and akt1 expression and phosphorylation in breast cancer cell resistance to Paclitaxel, Doxorubicin, and gemcitabine. Mol Pharmacol 70:1045-1052.
    • (2006) Mol Pharmacol , vol.70 , pp. 1045-1052
    • Liang, K.1    Lu, Y.2    Li, X.3    Zeng, X.4    Glazer, R.I.5    Mills, G.B.6    Fan, Z.7
  • 33
    • 3142548954 scopus 로고    scopus 로고
    • Fetal alcohol syndrome at the cellular level
    • discussion 151
    • Olney JW (2004) Fetal alcohol syndrome at the cellular level. Addict Biol 9:137-149; discussion 151.
    • (2004) Addict Biol , vol.9 , pp. 137-149
    • Olney, J.W.1
  • 34
    • 3042765843 scopus 로고    scopus 로고
    • Ribosomal S6 kinase as a mediator of keratinocyte growth factor-induced activation of Akt in epithelial cells
    • Pan ZZ, Devaux Y, Ray P (2004) Ribosomal S6 kinase as a mediator of keratinocyte growth factor-induced activation of Akt in epithelial cells. Mol Biol Cell 15:3106-3113.
    • (2004) Mol Biol Cell , vol.15 , pp. 3106-3113
    • Pan, Z.Z.1    Devaux, Y.2    Ray, P.3
  • 35
    • 0033151613 scopus 로고    scopus 로고
    • A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans
    • Paradis S, Ailion M, Toker A, Thomas JH, Ruvkun G (1999) A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans. Genes Dev 13:1438-1452.
    • (1999) Genes Dev , vol.13 , pp. 1438-1452
    • Paradis, S.1    Ailion, M.2    Toker, A.3    Thomas, J.H.4    Ruvkun, G.5
  • 37
    • 0037034928 scopus 로고    scopus 로고
    • Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine)
    • Sato S, Fujita N, Tsuruo T (2002) Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine). Oncogene 21:1727-1738.
    • (2002) Oncogene , vol.21 , pp. 1727-1738
    • Sato, S.1    Fujita, N.2    Tsuruo, T.3
  • 38
    • 4043102610 scopus 로고    scopus 로고
    • Involvement of 3-phosphoinositide- dependent protein kinase-1 in the MEK/MAPK signal transduction pathway
    • Sato S, Fujita N, Tsuruo T (2004) Involvement of 3-phosphoinositide- dependent protein kinase-1 in the MEK/MAPK signal transduction pathway. J Biol Chem 279:33759-33767.
    • (2004) J Biol Chem , vol.279 , pp. 33759-33767
    • Sato, S.1    Fujita, N.2    Tsuruo, T.3
  • 39
    • 0026446686 scopus 로고
    • Identification of a minimal transforming domain of p53: Negative dominance through abrogation of sequence-specific DNA binding
    • Shaulian E, Zauberman A, Ginsberg D, Oren M (1992) Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding. Mol Cell Biol 12:5581-5592.
    • (1992) Mol Cell Biol , vol.12 , pp. 5581-5592
    • Shaulian, E.1    Zauberman, A.2    Ginsberg, D.3    Oren, M.4
  • 41
    • 10044281770 scopus 로고    scopus 로고
    • Activation of p90 Rsk1 is sufficient for differentiation of PC12 cells
    • Silverman E, Frödin M, Gammeltoft S, Maller JL (2004) Activation of p90 Rsk1 is sufficient for differentiation of PC12 cells. Mol Cell Biol 24:10573-10583.
    • (2004) Mol Cell Biol , vol.24 , pp. 10573-10583
    • Silverman, E.1    Frödin, M.2    Gammeltoft, S.3    Maller, J.L.4
  • 42
    • 35448966080 scopus 로고    scopus 로고
    • Role of kinase suppressor of Ras-1 in neuronal survival signaling by extracellular signalregulated kinase 1/2
    • Szatmari E, Kalita KB, Kharebava G, Hetman M (2007) Role of kinase suppressor of Ras-1 in neuronal survival signaling by extracellular signalregulated kinase 1/2. J Neurosci 27:11389-11400.
    • (2007) J Neurosci , vol.27 , pp. 11389-11400
    • Szatmari, E.1    Kalita, K.B.2    Kharebava, G.3    Hetman, M.4
  • 43
    • 33845904217 scopus 로고    scopus 로고
    • ERK1 and ERK2 mitogen-activated protein kinases affect Rasdependent cell signaling differentially
    • Vantaggiato C, Formentini I, Bondanza A, Bonini C, Naldini L, Brambilla R (2006) ERK1 and ERK2 mitogen-activated protein kinases affect Rasdependent cell signaling differentially. J Biol 5:14.
    • (2006) J Biol , vol.5 , pp. 14
    • Vantaggiato, C.1    Formentini, I.2    Bondanza, A.3    Bonini, C.4    Naldini, L.5    Brambilla, R.6
  • 44
    • 8644243021 scopus 로고    scopus 로고
    • Ternary complex factor-serum response factor complex-regulated gene activity is required for cellular proliferation and inhibition of apoptotic cell death
    • Vickers ER, Kasza A, Kurnaz IA, Seifert A, Zeef LA, O'donnell A, Hayes A, Sharrocks AD (2004) Ternary complex factor-serum response factor complex-regulated gene activity is required for cellular proliferation and inhibition of apoptotic cell death. Mol Cell Biol 24:10340-10351.
    • (2004) Mol Cell Biol , vol.24 , pp. 10340-10351
    • Vickers, E.R.1    Kasza, A.2    Kurnaz, I.A.3    Seifert, A.4    Zeef, L.A.5    O'donnell, A.6    Hayes, A.7    Sharrocks, A.D.8
  • 45
    • 0034704141 scopus 로고    scopus 로고
    • Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1
    • Wick MJ, Dong LQ, Riojas RA, Ramos FJ, Liu F (2000) Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1. J Biol Chem 275:40400-40406.
    • (2000) J Biol Chem , vol.275 , pp. 40400-40406
    • Wick, M.J.1    Dong, L.Q.2    Riojas, R.A.3    Ramos, F.J.4    Liu, F.5
  • 47
    • 23744452775 scopus 로고    scopus 로고
    • A disintegrin and metalloprotease 21 (ADAM21) is associated with neurogenesis and axonal growth in developing and adult rodent CNS
    • Yang P, Baker KA, Hagg T (2005) A disintegrin and metalloprotease 21 (ADAM21) is associated with neurogenesis and axonal growth in developing and adult rodent CNS. J Comp Neurol 490:163-179.
    • (2005) J Comp Neurol , vol.490 , pp. 163-179
    • Yang, P.1    Baker, K.A.2    Hagg, T.3
  • 48
    • 0032506514 scopus 로고    scopus 로고
    • Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway
    • Yano S, Tokumitsu H, Soderling TR (1998) Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway. Nature 396:584-587.
    • (1998) Nature , vol.396 , pp. 584-587
    • Yano, S.1    Tokumitsu, H.2    Soderling, T.R.3
  • 49
    • 14044252936 scopus 로고    scopus 로고
    • Both ERK and Wnt/beta-catenin pathways are involved in Wnt3a-induced proliferation
    • Yun MS, Kim SE, Jeon SH, Lee JS, Choi KY (2005) Both ERK and Wnt/beta-catenin pathways are involved in Wnt3a-induced proliferation. J Cell Sci 118:313-322.
    • (2005) J Cell Sci , vol.118 , pp. 313-322
    • Yun, M.S.1    Kim, S.E.2    Jeon, S.H.3    Lee, J.S.4    Choi, K.Y.5


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