In vivo role of the phosphate groove of PDK1 defined by knockin mutation

Journal of Cell Science

Volumn 118, Issue 21, 2005, Pages 5023-5034

  Collins, Barry J ^a   Deak, Maria ^a   Murray Tait, Vicky ^a   Storey, Kate G ^a   Alessi, Dario R ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

AGC kinase; Akt; Docking sites; PKC; Protein kinase; RSK; SGK

Indexed keywords

ISOENZYME; P90 RIBOSOMAL S6 KINASE; PHOSPHOPINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE; PROTEIN KINASE B; S6 KINASE; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BIRTH; CATALYSIS; CELL MUTANT; CELL VIABILITY; CONTROLLED STUDY; CRANIOFACIAL MALFORMATION; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME STABILITY; ENZYME STRUCTURE; FETUS; FETUS DEVELOPMENT; GENETIC CODE; HOMOZYGOSITY; IN VIVO STUDY; INTRAUTERINE GROWTH RETARDATION; KNOCKIN GENE; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; ENZYME ACTIVATION; FEMALE; HYDROPHOBICITY; IMMEDIATE-EARLY PROTEINS; ISOENZYMES; METHIONINE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA;

ANIMALIA;

EID: 27944482145     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02617     Document Type: Article

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