Somatic sequence variation at the Friedreich ataxia locus includes complete contraction of the expanded GAA triplet repeat, significant length variation in serially passaged lymphoblasts and enhanced mutagenesis in the flanking sequence

Human Molecular Genetics

Volumn 8, Issue 13, 1999, Pages 2425-2436

  Bidichandani, Sanjay I ^a   Purandare, Smita M ^a   Taylor, Ellen E ^a   Gumin, Glenice ^a   Machkhas, Hazem ^a,b   Harati, Yadollah ^a,b   Gibbs, Richard A ^a   Ashizawa, Tetsuo ^a,b   Patel, Pragna I ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; CONTROLLED STUDY; DNA TEMPLATE; FRIEDREICH ATAXIA; GENE LOCUS; GENE MUTATION; HUMAN; HUMAN CELL; INTRON; LYMPHOBLAST; LYMPHOBLASTOID CELL LINE; MUTAGENESIS; POINT MUTATION; PRIORITY JOURNAL; SOMATIC MUTATION; SOUTHERN BLOTTING; TRINUCLEOTIDE REPEAT;

ATAXIA;

EID: 0032739342     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/8.13.2425     Document Type: Article

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