Molecular basis of agonicity and antagonicity in the androgen receptor studied by molecular dynamics simulations

Journal of Molecular Graphics and Modelling

Volumn 27, Issue 4, 2008, Pages 452-458

  Bisson, William H ^a   Abagyan, Ruben ^a   Cavasotto, Claudio N ^b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Androgen receptor; Bicalutamide; Flutamide; Molecular dynamics; Nuclear receptor; Passive antagonism; Prostate cancer

Indexed keywords

BIOACTIVITY; LIGANDS; MOLECULAR DYNAMICS; NANOFLUIDICS; QUANTUM CHEMISTRY;

ANDROGEN RECEPTOR; BICALUTAMIDE; FLUTAMIDE; NUCLEAR RECEPTOR; PASSIVE ANTAGONISM; PROSTATE CANCER;

DYNAMICS;

BICALUTAMIDE; BOLDENONE; HYDROXYFLUTAMIDE; STEROID;

ARTICLE; BIOLOGICAL ACTIVITY; CRYSTAL STRUCTURE; DRUG ACTIVITY; DRUG STRUCTURE; GENE MUTATION; MOLECULAR DYNAMICS; PRIORITY JOURNAL; WILD TYPE;

ANILIDES; COMPUTER SIMULATION; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTATION; NITRILES; PROTEIN BINDING; RECEPTORS, ANDROGEN; STEROIDS; TOSYL COMPOUNDS;

EID: 55949119492     PISSN: 10933263     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmgm.2008.08.001     Document Type: Article

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