Homology modeling using multiple molecular dynamics simulations and docking studies of the human androgen receptor ligand binding domain bound to testosterone and nonsteroidal ligands

Journal of Medicinal Chemistry

Volumn 44, Issue 11, 2001, Pages 1729-1740

  Marhefka, C A ^a   Moore II, B M ^a   Bishop, T C ^b   Kirkovsky, L ^a   Mukherjee, A ^a   Dalton, J T ^a   Miller, D D ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; ANDROGEN RECEPTOR STIMULATING AGENT; BICALUTAMIDE; FLUTAMIDE; HORMONE RECEPTOR STIMULATING AGENT; HYDROXYFLUTAMIDE; LIGAND; NILUTAMIDE; TESTOSTERONE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; HUMAN; LIGAND BINDING; MODEL; MOLECULAR DYNAMICS; MUTATION; RECEPTOR BINDING; SIMULATION; STEREOCHEMISTRY;

AMINO ACID SUBSTITUTION; BINDING SITES; BINDING, COMPETITIVE; CRYSTALLOGRAPHY, X-RAY; FLUTAMIDE; HUMANS; IMIDAZOLES; IMIDAZOLIDINES; LIGANDS; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ANDROGEN; RECEPTORS, PROGESTERONE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035942522     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0005353     Document Type: Article

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