Depletion of cellular cholesterol enhances macrophage MAPK activation by chitin microparticles but not by heat-killed Mycobacterium bovis BCG

American Journal of Physiology - Cell Physiology

Volumn 295, Issue 2, 2008, Pages

  Nishiyama, Akihito ^a   Shinohara, Tsutomu ^a   Pantuso, Traci ^a   Tsuji, Shoutaro ^a   Yamashita, Makiko ^a   Shinohara, Shizuka ^a   Myrvik, Quentin N ^c   Henriksen, Ruth Ann ^b   Shibata, Yoshimi ^a  

^a FLORIDA ATLANTIC UNIVERSITY   (United States)

^b EAST CAROLINA UNIVERSITY   (United States)

^c Florida Atlantic Univ ^*

Author keywords

Cyclooxygenase 2; Interleukin 10; Mitogen activated protein kinase activation; N acetyl D glucosamine polymer particles; Phagosome formation; Th1 cytokines

Indexed keywords

BACTERIAL DNA; BCG VACCINE; CHITIN; CHOLESTEROL; CYCLOOXYGENASE 2; INTERLEUKIN 10; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; OLIGODEOXYNUCLEOTIDE; TUMOR NECROSIS FACTOR ALPHA; BETA CYCLODEXTRIN DERIVATIVE; CPG OLIGONUCLEOTIDE; CPG-OLIGONUCLEOTIDE; IMMUNOLOGICAL ADJUVANT; MEMBRANE ANTIGEN; METHYL BETA CYCLODEXTRIN; METHYL-BETA-CYCLODEXTRIN; MITOGEN ACTIVATED PROTEIN KINASE; OLIGODEOXYRIBONUCLEOTIDE; PROSTAGLANDIN E2; PTGS2 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; MACROPHAGE ACTIVATION; MOUSE; MYCOBACTERIUM BOVIS; NONHUMAN; PHAGOCYTOSIS; PHAGOSOME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RNA SYNTHESIS; ANIMAL; CELL LINE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECT; HEAT; IMMUNOLOGY; MACROPHAGE; METABOLISM; PARTICLE SIZE; PHOSPHORYLATION; PHYSIOLOGY;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM BOVIS; MYCOBACTERIUM BOVIS BCG;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS, SURFACE; BETA-CYCLODEXTRINS; CELL LINE; CELL SURVIVAL; CHITIN; CHOLESTEROL; CYCLOOXYGENASE 2; DINOPROSTONE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEAT; INTERLEUKIN-10; MACROPHAGE ACTIVATION; MACROPHAGES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYCOBACTERIUM BOVIS; OLIGODEOXYRIBONUCLEOTIDES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PARTICLE SIZE; PHAGOCYTOSIS; PHAGOSOMES; PHOSPHORYLATION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 55949098778     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00446.2007     Document Type: Article

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