Phagocytosis of N-acetyl-d-glucosamine particles, a Th1 adjuvant, by RAW 264.7 cells results in MAPK activation and TNF-α, but not IL-10, production

Cellular Immunology

Volumn 239, Issue 2, 2006, Pages 103-112

  Nishiyama, Akihito ^a   Tsuji, Shoutaro ^a   Yamashita, Makiko ^a   Henriksen, Ruth Ann ^b   Myrvik, Quentin N ^c   Shibata, Yoshimi ^a  

^a FLORIDA ATLANTIC UNIVERSITY   (United States)

^b EAST CAROLINA UNIVERSITY   (United States)

^c NONE   (United States)

Author keywords

IL 10; Mitogen activated protein kinases; N acetyl d glucosamine polymer particles; Phagosomes; Th1 adjuvant

Indexed keywords

CHITIN DERIVATIVE; CPG OLIGODEOXYNUCLEOTIDE; CYCLOOXYGENASE 2; ENDOTOXIN; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 10; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; N ACETYLGLUCOSAMINE; POLYMER; PROSTAGLANDIN E2; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; VIRULENCE FACTOR;

ANIMAL CELL; ARTICLE; CELL STRAIN; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; IMMUNE RESPONSE; MACROPHAGE; MOUSE; MYCOBACTERIUM; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; TH1 CELL;

ACETYLGLUCOSAMINE; ADJUVANTS, IMMUNOLOGIC; ANIMALS; CELL LINE; CHITIN; ENZYME ACTIVATION; FEMALE; INTERLEUKIN-10; MACROPHAGES; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASES; PARTICLE SIZE; PHAGOCYTOSIS; TH1 CELLS; TUMOR NECROSIS FACTOR-ALPHA;

BACTERIA (MICROORGANISMS); MURINAE;

EID: 33745855443     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2006.04.003     Document Type: Article

References (48)

1. Herr H.W. Restaging transurethral resection of high risk superficial bladder cancer improves the initial response to bacillus Calmette-Guerin therapy. J. Urol. 174 (2005) 2134-2137
2. Pearson C.M. Development of arthritis, periarthritis and periostitis in rats given adjuvants. Proc. Soc. Exp. Biol. Med. 91 (1956) 95-101
3. Billiau A., and Matthys P. Modes of action of Freund's adjuvants in experimental models of autoimmune diseases. J. Leukoc. Biol. 70 (2001) 849-860
4. Chillingworth N.L., and Donaldson L.F. Characterisation of a Freund's complete adjuvant-induced model of chronic arthritis in mice. J. Neurosci. Methods 128 (2003) 45-52
5. Shibata Y., Honda I., Justice J.P., Van Scott M.R., Nakamura R.M., and Myrvik N.Q. Th1 adjuvant N-acetyl-d-glucosamine polymer up-regulates Th1 immunity but down-regulates Th2 immunity against a mycobacterial protein (MPB-59) in interleukin-10-knockout and wild-type mice. Infect. Immun. 69 (2001) 6123-6130
6. Shibata Y., Henriksen R.A., Honda I., Nakamura R.M., and Myrvik Q.N. Splenic PGE2-releasing macrophages regulate Th1 and Th2 immune responses in mice treated with heat-killed BCG. J. Leukoc. Biol. 78 (2005) 1281-1290
7. Power C.A., Wei G., and Bretscher P.A. Mycobacterial dose defines the Th1/Th2 nature of the immune response independently of whether immunization is administered by the intravenous, subcutaneous, or intradermal route. Infect. Immun. 66 (1998) 5743-5750
8. Orme I.M., Roberts A.D., Griffin J.P., and Abrams J.S. Cytokine secretion by CD4 T lymphocytes acquired in response to Mycobacterium tuberculosis infection. J. Immunol. 151 (1993) 518-525
9. Kline J.N., Waldschmidt T.J., Businga T.R., Lemish J.E., Weinstock J.V., Thorne P.S., and Krieg A.M. Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma. J. Immunol. 160 (1998) 2555-2559
10. Roman M., Martin-Orozco E., Goodman J.S., Nguyen M.D., Sato Y., Ronaghy A., Kornbluth R.S., Richman D.D., Carson D.A., and Raz E. Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants. Nat. Med. 3 (1997) 849-854
11. Halpern M.D., Kurlander R.J., and Pisetsky D.S. Bacterial DNA induces murine interferon-gamma production by stimulation of interleukin-12 and tumor necrosis factor-alpha. Cell. Immunol. 167 (1996) 72-78
12. Agrawal S., and Kandimalla E.R. Medicinal chemistry and therapeutic potential of CpG DNA. Trends Mol. Med. 8 (2002) 114-121
13. Crabtree T.D., Jin L., Raymond D.P., Pelletier S.J., Houlgrave C.W., Gleason T.G., Pruett T.L., and Sawyer R.G. Preexposure of murine macrophages to CpG oligonucleotide results in a biphasic tumor necrosis factor alpha response to subsequent lipopolysaccharide challenge. Infect. Immun. 69 (2001) 2123-2129
14. Shibata Y., Foster L.A., Kurimoto M., Okamura H., Nakamura R.M., Kawajiri K., Justice J.P., Van Scott M.R., Myrvik Q.N., and Metzger W.J. Immunoregulatory roles of IL-10 in innate immunity: IL-10 inhibits macrophage production of IFN-gamma-inducing factors but enhances NK cell production of IFN-gamma. J. Immunol. 161 (1998) 4283-4288
15. Haddad J.J., Saade N.E., and Safieh-Garabedian B. Interleukin-10 and the regulation of mitogen-activated protein kinases: are these signalling modules targets for the anti-inflammatory action of this cytokine?. Cell. Signal. 15 (2003) 255-267
16. Fiorentino D.F., Zlotnik A., Mosmann T.R., Howard M., and O'Garra A. IL-10 inhibits cytokine production by activated macrophages. J. Immunol. 147 (1991) 3815-3822
17. Shibata Y., Foster L.A., Metzger W.J., and Myrvik Q.N. Alveolar macrophage priming by intravenous administration of chitin particles, polymers of N-acetyl-d-glucosamine, in mice. Infect. Immun. 65 (1997) 1734-1741
18. Shibata Y., Metzger W.J., and Myrvik Q.N. Chitin particle-induced cell-mediated immunity is inhibited by soluble mannan: mannose receptor-mediated phagocytosis initiates IL-12 production. J. Immunol. 159 (1997) 2462-2467
19. Shibata Y., Foster L.A., Bradfield J.F., and Myrvik Q.N. Oral administration of chitin down-regulates serum IgE levels and lung eosinophilia in the allergic mouse. J. Immunol. 164 (2000) 1314-1321
20. Strong P., Clark H., and Reid K. Intranasal application of chitin microparticles down-regulates symptoms of allergic hypersensitivity to Dermatophagoides pteronyssinus and Aspergillus fumigatus in murine models of allergy. Clin. Exp. Allergy 32 (2002) 1794-1800
21. Hamajima K., Kojima Y., Matsui K., Toda Y., Jounai N., Ozaki T., Xin K.Q., Strong P., and Okuda K. Chitin micro-particles (CMP): a useful adjuvant for inducing viral specific immunity when delivered intranasally with an HIV-DNA vaccine. Viral Immunol. 16 (2003) 541-547
22. Guha M., and Mackman N. LPS induction of gene expression in human monocytes. Cell. Signal. 13 (2001) 85-94
23. Hacker H., Mischak H., Miethke T., Liptay S., Schmid R., Sparwasser T., Heeg K., Lipford G.B., and Wagner H. CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation. EMBO J. 17 (1998) 6230-6240
24. Kim S.H., Kim J., and Sharma R.P. Inhibition of p38 and ERK MAP kinases blocks endotoxin-induced nitric oxide production and differentially modulates cytokine expression. Pharmacol. Res. 49 (2004) 433-439
25. Shi L., Kishore R., McMullen M.R., and Nagy L.E. Lipopolysaccharide stimulation of ERK1/2 increases TNF-alpha production via Egr-1. Am. J. Physiol. Cell Physiol. 282 (2002) C1205-C1211
26. Hacker H., Redecke V., Blagoev B., Kratchmarova I., Hsu L.C., Wang G.G., Kamps M.P., Raz E., Wagner H., Hacker G., Mann M., and Karin M. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature 439 (2006) 204-207
27. Akira S. Toll-like receptor signaling. J. Biol. Chem. 278 (2003) 38105-38108
28. Dunzendorfer S., Lee H.K., Soldau K., and Tobias P.S. TLR4 is the signaling but not the lipopolysaccharide uptake receptor. J. Immunol. 173 (2004) 1166-1170
29. Kopp E., and Medzhitov R. Recognition of microbial infection by Toll-like receptors. Curr. Opin. Immunol. 15 (2003) 396-401
30. Foey A.D., Parry S.L., Williams L.M., Feldmann M., Foxwell B.M., and Brennan F.M. Regulation of monocyte IL-10 synthesis by endogenous IL-1 and TNF-alpha: role of the p38 and p42/44 mitogen-activated protein kinases. J. Immunol. 160 (1998) 920-928
31. Treffkorn L., Scheibe R., Maruyama T., and Dieter P. PGE2 exerts its effect on the LPS-induced release of TNF-alpha, ET-1, IL-1alpha, IL-6 and IL-10 via the EP2 and EP4 receptor in rat liver macrophages. Prostaglandins Other Lipid Mediat. 74 (2004) 113-123
32. Shinomiya S., Naraba H., Ueno A., Utsunomiya I., Maruyama T., Ohuchida S., Ushikubi F., Yuki K., Narumiya S., Sugimoto Y., Ichikawa A., and Oh-ishi S. Regulation of TNFalpha and interleukin-10 production by prostaglandins I(2) and E(2): studies with prostaglandin receptor-deficient mice and prostaglandin E-receptor subtype-selective synthetic agonists. Biochem. Pharmacol. 61 (2001) 1153-1160
33. Paul A., Cuenda A., Bryant C.E., Murray J., Chilvers E.R., Cohen P., Gould G.W., and Plevin R. Involvement of mitogen-activated protein kinase homologues in the regulation of lipopolysaccharide-mediated induction of cyclo-oxygenase-2 but not nitric oxide synthase in RAW 264.7 macrophages. Cell. Signal. 11 (1999) 491-497
34. Verreck F.A., de Boer T., Langenberg D.M., Hoeve M.A., Kramer M., Vaisberg E., Kastelein R., Kolk A., de Waal-Malefyt R., and Ottenhoff T.H. Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria. Proc. Natl. Acad. Sci. USA 101 (2004) 4560-4565
35. Petsch D., Beeskow T.C., Anspach F.B., and Deckwer W.D. Membrane adsorbers for selective removal of bacterial endotoxin. J. Chromatogr. B. Biomed. Sci. Appl. 693 (1997) 79-91
36. Yeo S.J., Gravis D., Yoon J.G., and Yi A.K. Myeloid differentiation factor 88-dependent transcriptional regulation of cyclooxygenase-2 expression by CpG DNA: role of NF-kappaB and p38. J. Biol. Chem. 278 (2003) 22563-22573
37. Ma W., Lim W., Gee K., Aucoin S., Nandan D., Kozlowski M., Diaz-Mitoma F., and Kumar A. The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages. J. Biol. Chem. 276 (2001) 13664-13674
38. Bjersing J.L., Eriksson K., Tarkowski A., and Collins L.V. The arthritogenic and immunostimulatory properties of phosphorothioate oligodeoxynucleotides rely on synergy between the activities of the nuclease-resistant backbone and CpG motifs. Inflammation 28 (2004) 39-51
39. Shibata Y. Prostaglandin E2 release triggered by phagocytosis of latex particles. A distinct association with prostaglandin synthase isozymes in bone marrow macrophages. J. Immunol. 154 (1995) 2878-2887
40. Lamprou I., Tsakas S., Theodorou G.L., Karakantza M., Lampropoulou M., and Marmaras W.J. Uptake of LPS/E. coli/latex beads via distinct signalling pathways in medfly hemocytes: the role of MAP kinases activation and protein secretion. Biochim. Biophys. Acta 1744 (2005) 1-10
41. Mathur R.K., Awasthi A., Wadhone P., Ramanamurthy B., and Saha B. Reciprocal CD40 signals through p38MAPK and ERK-1/2 induce counteracting immune responses. Nat. Med. 10 (2004) 540-544
42. Krysan K., Reckamp K.L., Dalwadi H., Sharma S., Rozengurt E., Dohadwala M., and Dubinett S.M. Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner. Cancer Res. 65 (2005) 6275-6281
43. Fiebich B.L., Schleicher S., Spleiss O., Czygan M., and Hull M. Mechanisms of prostaglandin E2-induced interleukin-6 release in astrocytes: possible involvement of EP4-like receptors, p38 mitogen-activated protein kinase and protein kinase. C. J. Neurochem. 79 (2001) 950-958
44. Chin B.Y., Choi M.E., Burdick M.D., Strieter R.M., Risby T.H., and Choi A.M. Induction of apoptosis by particulate matter: role of TNF-alpha and MAPK. Am. J. Physiol. 275 (1998) L942-L949
45. Kahlke V., Angele M.K., Ayala A., Schwacha M.G., Cioffi W.G., Bland K.I., and Chaudry I.H. Immune dysfunction following trauma-haemorrhage: influence of gender and age. Cytokine 12 (2000) 69-77
46. Murata Y., Amao M., Yoneda J., and Hamuro J. Intracellular thiol redox status of macrophages directs the Th1 skewing in thioredoxin transgenic mice during aging. Mol. Immunol. 38 (2002) 747-757
47. Genovese F., Mancuso G., Cuzzola M., Biondo C., Beninati C., Delfino D., and Teti G. Role of IL-10 in a neonatal mouse listeriosis model. J. Immunol. 163 (1999) 2777-2782
48. Mallat Z., Heymes C., Ohan J., Faggin E., Leseche G., and Tedgui A. Expression of interleukin-10 in advanced human atherosclerotic plaques: relation to inducible nitric oxide synthase expression and cell death. Arterioscler. Thromb. Vasc. Biol. 19 (1999) 611-616