-
1
-
-
0037246571
-
Decrease in toxic potential of mixed tensides maintained below the critical micelle concentration: an in vitro study
-
Benassi L., Bertazzoni G., Magnoni C., Rinaldi M., Fontanesi C., and Seidenari S. Decrease in toxic potential of mixed tensides maintained below the critical micelle concentration: an in vitro study. Skin. Pharmacol. Appl. Skin Physiol. 16 (2003) 156-164
-
(2003)
Skin. Pharmacol. Appl. Skin Physiol.
, vol.16
, pp. 156-164
-
-
Benassi, L.1
Bertazzoni, G.2
Magnoni, C.3
Rinaldi, M.4
Fontanesi, C.5
Seidenari, S.6
-
2
-
-
1642304142
-
Assessment of primary eye and skin irritants by in vitro cytotoxicity and phototoxicity models: an in vitro approach of arginine-based surfactant-induced irritation
-
Benavides T., Mitjans M., Martínez V., Clapés P., Infante M.R., Clothier R.H., and Vinardell M.P. Assessment of primary eye and skin irritants by in vitro cytotoxicity and phototoxicity models: an in vitro approach of arginine-based surfactant-induced irritation. Toxicology 197 (2004) 229-237
-
(2004)
Toxicology
, vol.197
, pp. 229-237
-
-
Benavides, T.1
Mitjans, M.2
Martínez, V.3
Clapés, P.4
Infante, M.R.5
Clothier, R.H.6
Vinardell, M.P.7
-
3
-
-
3543098569
-
Assessment of the potential irritation and photoirritation of novel amino acid-based surfactants by in vitro methods as alternative to the animal tests
-
Benavides T., Martínez V., Mitjans M., Infante M.R., Morán C., Clapés P., Clothier R., and Vinardell M.P. Assessment of the potential irritation and photoirritation of novel amino acid-based surfactants by in vitro methods as alternative to the animal tests. Toxicology 201 (2004) 87-93
-
(2004)
Toxicology
, vol.201
, pp. 87-93
-
-
Benavides, T.1
Martínez, V.2
Mitjans, M.3
Infante, M.R.4
Morán, C.5
Clapés, P.6
Clothier, R.7
Vinardell, M.P.8
-
4
-
-
0021990499
-
Toxicity determined in vitro by morphological alterations and neutral red absorption
-
Borenfreud E., and Puerner J.A. Toxicity determined in vitro by morphological alterations and neutral red absorption. Toxicol. Lett. 24 (1985) 119-124
-
(1985)
Toxicol. Lett.
, vol.24
, pp. 119-124
-
-
Borenfreud, E.1
Puerner, J.A.2
-
5
-
-
2842588325
-
MEIC evaluation of acute systemic toxicity. Part II. Results from 68 toxicity assays used to test the first 30 reference chemicals and a comparative cytotoxicity analysis
-
Clemedson C., McFarlane-Abdulla E., Andersson M., Barile F.A., Calleja M.C., Chesné C., Clothier R., Cottin M., Curren R., Dierickx M.G., Fiskesjö G., Garza-Ocañas, Gómex-Lechón M.J., Gülden M., Isomaa B., Janus J., Judge P., Kahru A., Kemp R.B., Kerszman G., Kristen U., Kunimoto M., Kärenlampi S., Lavrijsen K., Lewan L., Lilius H., Malmsten A., Ohno T., Persoone G., Petersson R., Roguet R., Romert L., Sandberg M., Sawyer T.W., Seibert H., Shrivastava R., Sjöström M., Stammati A., Tanaka N., Torres-Alanis O., Voss J.-U., Wakuri S., Walum E., Wang X., Zucco F., and Ekwall B. MEIC evaluation of acute systemic toxicity. Part II. Results from 68 toxicity assays used to test the first 30 reference chemicals and a comparative cytotoxicity analysis. ATLA 24 (1996) 273-311
-
(1996)
ATLA
, vol.24
, pp. 273-311
-
-
Clemedson, C.1
McFarlane-Abdulla, E.2
Andersson, M.3
Barile, F.A.4
Calleja, M.C.5
Chesné, C.6
Clothier, R.7
Cottin, M.8
Curren, R.9
Dierickx, M.G.10
Fiskesjö, G.11
Garza-Ocañas12
Gómex-Lechón, M.J.13
Gülden, M.14
Isomaa, B.15
Janus, J.16
Judge, P.17
Kahru, A.18
Kemp, R.B.19
Kerszman, G.20
Kristen, U.21
Kunimoto, M.22
Kärenlampi, S.23
Lavrijsen, K.24
Lewan, L.25
Lilius, H.26
Malmsten, A.27
Ohno, T.28
Persoone, G.29
Petersson, R.30
Roguet, R.31
Romert, L.32
Sandberg, M.33
Sawyer, T.W.34
Seibert, H.35
Shrivastava, R.36
Sjöström, M.37
Stammati, A.38
Tanaka, N.39
Torres-Alanis, O.40
Voss, J.-U.41
Wakuri, S.42
Walum, E.43
Wang, X.44
Zucco, F.45
Ekwall, B.46
more..
-
6
-
-
34250674906
-
Normal human keratinocyte assay to predict the human irritancy response
-
Clothier R., and Khammo N. Normal human keratinocyte assay to predict the human irritancy response. Nat. Protoc. 1 1 (2006) 444-451
-
(2006)
Nat. Protoc.
, vol.1
, Issue.1
, pp. 444-451
-
-
Clothier, R.1
Khammo, N.2
-
7
-
-
0030782045
-
An in vitro approach to the evaluation of repeat exposure in the prediction of toxicity
-
Clothier R.H., Beed M., Samson R., and Ward R. An in vitro approach to the evaluation of repeat exposure in the prediction of toxicity. Toxicol. In Vitro 11 (1997) 679-682
-
(1997)
Toxicol. In Vitro
, vol.11
, pp. 679-682
-
-
Clothier, R.H.1
Beed, M.2
Samson, R.3
Ward, R.4
-
8
-
-
0032891414
-
The use of human keratinocytes in the EU/COLIPA international in vitro phototoxicity test validation study and the ECVAM/COLIPA study on UV filterchemicals
-
Clothier R., Willshaw A., Cox H., Garle M., Bowler H., and Combes R. The use of human keratinocytes in the EU/COLIPA international in vitro phototoxicity test validation study and the ECVAM/COLIPA study on UV filterchemicals. ATLA 27 (1999) 247-259
-
(1999)
ATLA
, vol.27
, pp. 247-259
-
-
Clothier, R.1
Willshaw, A.2
Cox, H.3
Garle, M.4
Bowler, H.5
Combes, R.6
-
9
-
-
0036754712
-
The prediction of human skin responses by using the combined in vitro fluorescein leakage/Alamar Blue (resazurin) assay
-
Clothier R., Starzec G., Pradel L., Baxter V., Jones M., Cox H., and Noble L. The prediction of human skin responses by using the combined in vitro fluorescein leakage/Alamar Blue (resazurin) assay. ATLA Altern. Lab. Anim. 30 (2002) 493-504
-
(2002)
ATLA Altern. Lab. Anim.
, vol.30
, pp. 493-504
-
-
Clothier, R.1
Starzec, G.2
Pradel, L.3
Baxter, V.4
Jones, M.5
Cox, H.6
Noble, L.7
-
10
-
-
36348975685
-
Phototoxicity and acute toxicity studies conducted by the frame alternatives laboratory: a brief review
-
Clothier R.H. Phototoxicity and acute toxicity studies conducted by the frame alternatives laboratory: a brief review. ATLA 35 (2007) 515-519
-
(2007)
ATLA
, vol.35
, pp. 515-519
-
-
Clothier, R.H.1
-
11
-
-
33645241608
-
Assessment of the phototoxic hazard of some essential oils using modified 3T3 neutral red uptake assay
-
Dijoux N., Guingand Y., Bourgeois C., Durand S., Fromageot C., Combe C., and Ferret P. Assessment of the phototoxic hazard of some essential oils using modified 3T3 neutral red uptake assay. Toxicol. In Vitro 20 (2006) 480-489
-
(2006)
Toxicol. In Vitro
, vol.20
, pp. 480-489
-
-
Dijoux, N.1
Guingand, Y.2
Bourgeois, C.3
Durand, S.4
Fromageot, C.5
Combe, C.6
Ferret, P.7
-
12
-
-
0036460003
-
Reconstructed skin kits: reproducibility of cutaneous irritancy testing
-
Faller C., and Bracher M. Reconstructed skin kits: reproducibility of cutaneous irritancy testing. Skin Pharmacol. Appl. Skin Physiol. 1 (2002) 74-91
-
(2002)
Skin Pharmacol. Appl. Skin Physiol.
, vol.1
, pp. 74-91
-
-
Faller, C.1
Bracher, M.2
-
13
-
-
33748525168
-
Assessment of the skin irritation potential of chemicals by using the SkinEthic reconstructed human epidermal model and the common skin irritation protocol evaluated in the ECVAM skin irritation validation study
-
Kandarova H., Liebsch M., Schmidt E., Genschow E., Traue D., Spielmann H., Meyer K., Steinhoff C., Tornier C., De Wever B., and Rosdy M. Assessment of the skin irritation potential of chemicals by using the SkinEthic reconstructed human epidermal model and the common skin irritation protocol evaluated in the ECVAM skin irritation validation study. Altern. Lab. Anim. 34 (2006) 393-406
-
(2006)
Altern. Lab. Anim.
, vol.34
, pp. 393-406
-
-
Kandarova, H.1
Liebsch, M.2
Schmidt, E.3
Genschow, E.4
Traue, D.5
Spielmann, H.6
Meyer, K.7
Steinhoff, C.8
Tornier, C.9
De Wever, B.10
Rosdy, M.11
-
14
-
-
0028335894
-
Discrimination of the irritancy potential of surfactants in vitro by two cytotoxicity assays using normal human keratinocytes, HaCaT cells and 3T3 mouse fibroblast: correlation with in vivo data from a soap chamber assay
-
Korting H.C., Herzinger T., Hartinger A., Kerscher M., Angerpointner T., and Maibach H.I. Discrimination of the irritancy potential of surfactants in vitro by two cytotoxicity assays using normal human keratinocytes, HaCaT cells and 3T3 mouse fibroblast: correlation with in vivo data from a soap chamber assay. J. Dermatol. Sci. 7 (1994) 119-129
-
(1994)
J. Dermatol. Sci.
, vol.7
, pp. 119-129
-
-
Korting, H.C.1
Herzinger, T.2
Hartinger, A.3
Kerscher, M.4
Angerpointner, T.5
Maibach, H.I.6
-
15
-
-
0033921110
-
In vitro cytotoxicity tests on cultures human skin fibroblasts to predict skin irritation potential of surfactants
-
Lee J.K., Kim D.B., Kim J.I., and Kim P.Y. In vitro cytotoxicity tests on cultures human skin fibroblasts to predict skin irritation potential of surfactants. Toxicol. In Vitro 14 (2000) 345-349
-
(2000)
Toxicol. In Vitro
, vol.14
, pp. 345-349
-
-
Lee, J.K.1
Kim, D.B.2
Kim, J.I.3
Kim, P.Y.4
-
16
-
-
0025996187
-
Development of an in vitro test system with human skin cells for evaluation of phototoxicity
-
Maier K., Schmitt-Landgraf R., and Siegemund B. Development of an in vitro test system with human skin cells for evaluation of phototoxicity. Toxicol. In Vitro 5 (1991) 457-461
-
(1991)
Toxicol. In Vitro
, vol.5
, pp. 457-461
-
-
Maier, K.1
Schmitt-Landgraf, R.2
Siegemund, B.3
-
17
-
-
0142042423
-
Low potential ocular irritation of arginine-based gemini surfactants and their mixtures with nonionic and zwitterionic surfactants
-
Mitjans M., Martínez V., Clapés P., Perez L., Infante M.R., and Vinardell M.P. Low potential ocular irritation of arginine-based gemini surfactants and their mixtures with nonionic and zwitterionic surfactants. Pharm. Res. 20 (2003) 1697-1701
-
(2003)
Pharm. Res.
, vol.20
, pp. 1697-1701
-
-
Mitjans, M.1
Martínez, V.2
Clapés, P.3
Perez, L.4
Infante, M.R.5
Vinardell, M.P.6
-
20
-
-
20444375525
-
The human epidermis models EpiSkin, SkinEthic and EpiDerm: an evaluation of morphology and their suitability for testing phototoxicity, irritancy, corrosivity, and substance transport
-
Netzlaff F., Lehr C.M., Wertz P.W., and Schaefer U.F. The human epidermis models EpiSkin, SkinEthic and EpiDerm: an evaluation of morphology and their suitability for testing phototoxicity, irritancy, corrosivity, and substance transport. Eur. J. Pharm. Biopharm. 60 (2005) 167-178
-
(2005)
Eur. J. Pharm. Biopharm.
, vol.60
, pp. 167-178
-
-
Netzlaff, F.1
Lehr, C.M.2
Wertz, P.W.3
Schaefer, U.F.4
-
21
-
-
0033856957
-
Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity
-
O'Brien J., Wilson I., Orton T., and Pognan F. Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity. Eur. J. Biochem. 267 (2000) 5421-5426
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 5421-5426
-
-
O'Brien, J.1
Wilson, I.2
Orton, T.3
Pognan, F.4
-
22
-
-
0028344686
-
An approach for development of alternative test methods based on mechanisms of skin irritation
-
Osborne R., and Perkins M.A. An approach for development of alternative test methods based on mechanisms of skin irritation. Food Chem. Toxicol. 32 (1994) 133-142
-
(1994)
Food Chem. Toxicol.
, vol.32
, pp. 133-142
-
-
Osborne, R.1
Perkins, M.A.2
-
23
-
-
36048943289
-
EU legislations affecting safety data availability of cosmetic ingredients
-
Pauwels M., and Rogiers V. EU legislations affecting safety data availability of cosmetic ingredients. Regul. Toxicol. Pharmacol. 49 3 (2007) 308-315
-
(2007)
Regul. Toxicol. Pharmacol.
, vol.49
, Issue.3
, pp. 308-315
-
-
Pauwels, M.1
Rogiers, V.2
-
24
-
-
36349009147
-
An evaluation of the effects photoactivation of bithionol, amiodarone and chlorpromazine on human keratinocytes in vitro
-
Reid L., Khammo N., and Clothier R.H. An evaluation of the effects photoactivation of bithionol, amiodarone and chlorpromazine on human keratinocytes in vitro. ATLA 35 (2007) 471-485
-
(2007)
ATLA
, vol.35
, pp. 471-485
-
-
Reid, L.1
Khammo, N.2
Clothier, R.H.3
-
26
-
-
47149105103
-
Good science must be the key factor in the development and use of alternative methods for safety assessment of cosmetics
-
Rogiers V., and Pauwels M. Good science must be the key factor in the development and use of alternative methods for safety assessment of cosmetics. ALTEX 23 (2006) 346-352
-
(2006)
ALTEX
, vol.23
, pp. 346-352
-
-
Rogiers, V.1
Pauwels, M.2
-
27
-
-
28844468793
-
Potential irritation of lysine derivative surfactants by hemolysis and HaCaT cell viability
-
Sánchez L., Mitjans M., Infante M.R., and Vinardell M.P. Potential irritation of lysine derivative surfactants by hemolysis and HaCaT cell viability. Toxicol. Lett. 161 (2006) 53-60
-
(2006)
Toxicol. Lett.
, vol.161
, pp. 53-60
-
-
Sánchez, L.1
Mitjans, M.2
Infante, M.R.3
Vinardell, M.P.4
-
28
-
-
33749649848
-
Determination of interleukin-1alpha in human NCTC 2544 keratinocyte cells as a predictor of skin irritation from lysine-based surfactants
-
Sánchez L., Mitjans M., Infante M.R., and Vinardell M.P. Determination of interleukin-1alpha in human NCTC 2544 keratinocyte cells as a predictor of skin irritation from lysine-based surfactants. Toxicol. Lett. 167 (2006) 40-46
-
(2006)
Toxicol. Lett.
, vol.167
, pp. 40-46
-
-
Sánchez, L.1
Mitjans, M.2
Infante, M.R.3
Vinardell, M.P.4
-
29
-
-
0031873718
-
The international EU/COLIPA in vitro phototoxicity validation study; results of phase II (blind trial). Part 1: the 3T3 NRU phototoxicity test
-
Spielmann H., Balls M., Dupuis J., Pape W.J., Pechovitch G., de Silva O., Holzhütter H.G., Clothier R., Desolle P., Gerberick F., Liebsch M., Lovell W.W., Maurer T., Pfannenbecker U., Potthast J.M., Csato M., Sladowski D., Steiling W., and Brantom P. The international EU/COLIPA in vitro phototoxicity validation study; results of phase II (blind trial). Part 1: the 3T3 NRU phototoxicity test. Toxicol. In Vitro 12 (1998) 305-327
-
(1998)
Toxicol. In Vitro
, vol.12
, pp. 305-327
-
-
Spielmann, H.1
Balls, M.2
Dupuis, J.3
Pape, W.J.4
Pechovitch, G.5
de Silva, O.6
Holzhütter, H.G.7
Clothier, R.8
Desolle, P.9
Gerberick, F.10
Liebsch, M.11
Lovell, W.W.12
Maurer, T.13
Pfannenbecker, U.14
Potthast, J.M.15
Csato, M.16
Sladowski, D.17
Steiling, W.18
Brantom, P.19
-
30
-
-
0034520168
-
The second ECVAM workshop on phototoxicity testing. The report and recommendations of ECVAM workshop 42
-
Spielmann H., Muller L., Averbeck D., Balls M., Brendler-Schwaab S., Castell J.V., Curren R., de Silva O., Gibbs N.K., Liebsch M., Lovell W.W., Merk H.F., Nash J.F., Neumann N.J., Pape W.J., Ulrich P., and Vohr H.W. The second ECVAM workshop on phototoxicity testing. The report and recommendations of ECVAM workshop 42. Altern. Lab. Anim. 28 6 (2000) 777-814
-
(2000)
Altern. Lab. Anim.
, vol.28
, Issue.6
, pp. 777-814
-
-
Spielmann, H.1
Muller, L.2
Averbeck, D.3
Balls, M.4
Brendler-Schwaab, S.5
Castell, J.V.6
Curren, R.7
de Silva, O.8
Gibbs, N.K.9
Liebsch, M.10
Lovell, W.W.11
Merk, H.F.12
Nash, J.F.13
Neumann, N.J.14
Pape, W.J.15
Ulrich, P.16
Vohr, H.W.17
-
31
-
-
0035166895
-
Quantitative assessment of primary skin irritants in vitro in a cytotoxicity model: comparison with in vivo human irritation tests
-
Wilhelm K.P., Bottjer B., and Siegers C.P. Quantitative assessment of primary skin irritants in vitro in a cytotoxicity model: comparison with in vivo human irritation tests. Br. J. Dermatol. 145 (2001) 709-715
-
(2001)
Br. J. Dermatol.
, vol.145
, pp. 709-715
-
-
Wilhelm, K.P.1
Bottjer, B.2
Siegers, C.P.3
-
32
-
-
0036177997
-
Follow-up to the ECVAM prevalidation study on in vitro tests for acute skin irritation. The European centre for the validation of alternative methods skin irritation task force report 2
-
Zuang V., Balls M., Botham P.A., Coquette A., Corsini E., Curren R.D., Elliott G.R., Fentem J.H., Heylings J.R., Liebsch M., Medina J., Roguet R., van de Sandt J.J., Wiemann C., and Worth A.P. Follow-up to the ECVAM prevalidation study on in vitro tests for acute skin irritation. The European centre for the validation of alternative methods skin irritation task force report 2. ATLA Altern. Lab. Anim. 30 (2002) 109-129
-
(2002)
ATLA Altern. Lab. Anim.
, vol.30
, pp. 109-129
-
-
Zuang, V.1
Balls, M.2
Botham, P.A.3
Coquette, A.4
Corsini, E.5
Curren, R.D.6
Elliott, G.R.7
Fentem, J.H.8
Heylings, J.R.9
Liebsch, M.10
Medina, J.11
Roguet, R.12
van de Sandt, J.J.13
Wiemann, C.14
Worth, A.P.15
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