Assessment of the skin irritation potential of chemicals by using the SkinEthic reconstructed human epidermal model and the common skin irritation protocol evaluated in the ECVAM skin irritation validation study

Alternatives to Laboratory Animals

Volumn 34, Issue 4, 2006, Pages 393-406

  Kandárová, Helena ^a   Liebsch, Manfred ^a   Schmidt, Elisabeth ^a   Genschow, Elke ^a   Traue, Dieter ^a   Spielmann, Horst ^a   Meyer, Kirstin ^b   Steinhoff, Claudia ^b   Tornier, Carine ^c   De Wever, Bart ^c   Rosdy, Martin ^c  

^a FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

^b BAYER PHARMA AG   (Germany)

^c SkinEthic Laboratories   (France)

Author keywords

Alternative methods; Common protocol; EpiDerm; EPISKIN; In vitro; Skin irritation; SkinEthic RHE; Validation

Indexed keywords

1,1,1 TRICHLOROETHANE; 10 UNDECENOIC ACID; BICARBONATE; BUTANOL; CHEMICAL COMPOUND; CITRONELLOL; CYTOKINE; DODECYL SULFATE SODIUM; HYDROXYCITRONELLAL; LAURIC ACID; LIMONENE; MYRISTIC ACID ISOPROPYL ESTER; OCTANE; PALMITIC ACID METHYL ESTER; PENTANE; PHENOL DERIVATIVE; POTASSIUM HYDROXIDE; PROPIONAMIDE DERIVATIVE; TRIAZOLE DERIVATIVE; UNDECANOIC ACID;

ADULT; ARTICLE; CLINICAL PROTOCOL; CONTROLLED STUDY; EPIDERMIS; GERMANY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MEDICAL ASSESSMENT; MEDICAL ETHICS; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN ANALYSIS; SKIN IRRITATION; TOXICITY TESTING; VALIDATION PROCESS;

ORYCTOLAGUS CUNICULUS;

EID: 33748525168     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290603400407     Document Type: Article

References (26)

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