메뉴 건너뛰기




Volumn 6, Issue 3, 1999, Pages 157-168

The problem of anti-pig antibodies in pig-to-primate xenografting: Current and novel methods of depletion and/or suppression of production of anti-pig antibodies

Author keywords

Anti Gal antibodies; Anti CD40 Ligand monoclonal antibody; B cells; Pig to primate; Tolerance; Xenotransplantation

Indexed keywords

ANTIIDIOTYPIC ANTIBODY; CD20 ANTIBODY; CD22 ANTIBODY; CLADRIBINE; CYCLOPHOSPHAMIDE; IMMUNOGLOBULIN; MELPHALAN; METHOTREXATE; MONOCLONAL ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; OLIGOSACCHARIDE; RITUXIMAB; UNCLASSIFIED DRUG; ZIDOVUDINE;

EID: 0032871066     PISSN: 0908665X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3089.1999.00030.x     Document Type: Review
Times cited : (74)

References (92)
  • 1
    • 0013924930 scopus 로고
    • Experimental renal heterotransplantation. I. in widely divergent species
    • PERPER RJ, NAJARIAN J. Experimental renal heterotransplantation. I. In widely divergent species. Transplantation 1966; 4: 377.
    • (1966) Transplantation , vol.4 , pp. 377
    • Perper, R.J.1    Najarian, J.2
  • 2
    • 0024297335 scopus 로고
    • Man, apes and Old World monkeys differ from other mammals in the expression of α-galactosyl epitopes on nucleated cells
    • GALILI U, SHOHET SB, KOBRIN E, et al. Man, apes and Old World monkeys differ from other mammals in the expression of α-galactosyl epitopes on nucleated cells J Biol Chem 1988; 263: 17755.
    • (1988) J Biol Chem , vol.263 , pp. 17755
    • Galili, U.1    Shohet, S.B.2    Kobrin, E.3
  • 3
    • 0021678856 scopus 로고
    • A unique natural human IgG antibody with anti-α-galactosyl specificity
    • GALILI U, RACHMILEWITZ EA, PELEG A, et al. A unique natural human IgG antibody with anti-α-galactosyl specificity J Exp Med 1984; 260: 1519.
    • (1984) J Exp Med , vol.260 , pp. 1519
    • Galili, U.1    Rachmilewitz, E.A.2    Peleg, A.3
  • 4
    • 0026623093 scopus 로고
    • Identification of carbohydrate structures that bind human anti-porcine antibodies: Implications for discordant xenografting in humans
    • GOOD AH, COOPER DKC, MALCOLM AJ, et al. Identification of carbohydrate structures that bind human anti-porcine antibodies: implications for discordant xenografting in humans. Transplant Proc 1992; 24: 559.
    • (1992) Transplant Proc , vol.24 , pp. 559
    • Good, A.H.1    Cooper, D.K.C.2    Malcolm, A.J.3
  • 5
    • 0027135892 scopus 로고
    • Identification of α-galatosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: Relevance to discordant xenografting in man
    • COOPER DKC, GOOD AH, KOREN E, et al. Identification of α-galatosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: relevance to discordant xenografting in man. Transplant Immunol 1993; 1: 198.
    • (1993) Transplant Immunol , vol.1 , pp. 198
    • Cooper, D.K.C.1    Good, A.H.2    Koren, E.3
  • 6
    • 0028171342 scopus 로고
    • Oligosaccharides and discordant xenotransplantation
    • COOPER DKC, KOREN E, ORIOL R. Oligosaccharides and discordant xenotransplantation. Immunol Rev 1994; 141: 31.
    • (1994) Immunol Rev , vol.141 , pp. 31
    • Cooper, D.K.C.1    Koren, E.2    Oriol, R.3
  • 7
    • 0027365748 scopus 로고
    • Binding and specificity of major immunoglobulin classes of preformed human anti-pig heart antibodies
    • KOREN E, NEETHLING FA, RICHARDS S, et al. Binding and specificity of major immunoglobulin classes of preformed human anti-pig heart antibodies. Transplant Int 1993; 6: 351.
    • (1993) Transplant Int , vol.6 , pp. 351
    • Koren, E.1    Neethling, F.A.2    Richards, S.3
  • 8
    • 0028155701 scopus 로고
    • Variability of anti-αGal antibodies in human serum and their relation to serum cytotoxicity against pig cells
    • KUJUNDZIC M, KOREN E, NEETHLING FA, et al. Variability of anti-αGal antibodies in human serum and their relation to serum cytotoxicity against pig cells. Xenotransplantation 1994; 1: 58.
    • (1994) Xenotransplantation , vol.1 , pp. 58
    • Kujundzic, M.1    Koren, E.2    Neethling, F.A.3
  • 9
    • 0023950850 scopus 로고
    • The interaction between the human anti-α-galactosyl IgG (anti-Gal) and bacteria of the human flora
    • GALILI U, MANDRELL RE, HAMADEH RM, et al. The interaction between the human anti-α-galactosyl IgG (anti-Gal) and bacteria of the human flora. Infect Immun 1988; 57: 1730.
    • (1988) Infect Immun , vol.57 , pp. 1730
    • Galili, U.1    Mandrell, R.E.2    Hamadeh, R.M.3
  • 10
    • 0027517325 scopus 로고
    • Antipig IgM antibodies in human serum react predominantly with Galα(1-3) Gal epitopes
    • SANDRIN MS, VAUGHAN HA, DABKOWSKI PL, et al. Antipig IgM antibodies in human serum react predominantly with Galα(1-3) Gal epitopes. Proc Natl Acad Sci USA 1993; 90: 11391.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11391
    • Sandrin, M.S.1    Vaughan, H.A.2    Dabkowski, P.L.3
  • 11
    • 0027508081 scopus 로고
    • Interaction of the natural anti-Gal antibody with agalactosyl epitopes: A major obstacle for xenotransplantation in humans
    • GALILI U. Interaction of the natural anti-Gal antibody with agalactosyl epitopes: a major obstacle for xenotransplantation in humans. Immunol Today 1993; 14: 480.
    • (1993) Immunol Today , vol.14 , pp. 480
    • Galili, U.1
  • 12
    • 0002360359 scopus 로고    scopus 로고
    • Anti-agalactosyl (anti-Gal) antibody damage beyond hyperacute rejection
    • COOPER DKC, KEMP E, PLATT JL, WHITE DJG, eds. Heidelberg: Springer
    • GALILI U. Anti-agalactosyl (anti-Gal) antibody damage beyond hyperacute rejection. In: COOPER DKC, KEMP E, PLATT JL, WHITE DJG, eds. Xenotransplantation, 2nd edn. Heidelberg: Springer 1997.
    • (1997) Xenotransplantation, 2nd Edn.
    • Galili, U.1
  • 14
    • 0027716847 scopus 로고
    • Carbohydrate antigens of pig tissues reacting with human natural antibodies as potential targets for hyperacute vascular rejection in pig-to-man organ xenotransplantation
    • ORIOL R, Ye Y, KOREN E, et al. Carbohydrate antigens of pig tissues reacting with human natural antibodies as potential targets for hyperacute vascular rejection in pig-to-man organ xenotransplantation Transplantation 1993; 56: 1433.
    • (1993) Transplantation , vol.56 , pp. 1433
    • Oriol, R.1    Ye, Y.2    Koren, E.3
  • 15
    • 0027942758 scopus 로고
    • Monomorphic and polymorphic carbohydrate antigens on pig tissues: Implications for organ xenotransplantation in the pig-to-man model
    • ORIOL R, BARTHOLD F, BERGEMER A-M, et al. Monomorphic and polymorphic carbohydrate antigens on pig tissues: Implications for organ xenotransplantation in the pig-to-man model. Transplant Int 1994; 7: 405.
    • (1994) Transplant Int , vol.7 , pp. 405
    • Oriol, R.1    Barthold, F.2    Bergemer, A.-M.3
  • 16
    • 0031931624 scopus 로고    scopus 로고
    • Xenoantigens and xenoantibodies
    • COOPER DKC. Xenoantigens and xenoantibodies. Xenotransplantation 1998; 5: 6.
    • (1998) Xenotransplantation , vol.5 , pp. 6
    • Cooper, D.K.C.1
  • 17
    • 0030852712 scopus 로고    scopus 로고
    • Relationship between ABO blood group and levels of Gal alpha,3galactose-reactive human immunoglobulin G
    • MCMORROW IM, COMRACK CA, NAZAREY PP, et al. Relationship between ABO blood group and levels of Gal alpha,3galactose-reactive human immunoglobulin G. Transplantation 1997; 64: 546.
    • (1997) Transplantation , vol.64 , pp. 546
    • Mcmorrow, I.M.1    Comrack, C.A.2    Nazarey, P.P.3
  • 18
    • 0029876177 scopus 로고    scopus 로고
    • Isohemagglutinins and xenoreactive antibodies: Members of a distinct family of natural antibodies
    • PARKER W, LUNDBERG-SWANSON KL, HOLZKNECHT ZE, et al. Isohemagglutinins and xenoreactive antibodies: members of a distinct family of natural antibodies. Hum Immunol 1996; 45: 94.
    • (1996) Hum Immunol , vol.45 , pp. 94
    • Parker, W.1    Lundberg-Swanson, K.L.2    Holzknecht, Z.E.3
  • 19
    • 0025838090 scopus 로고
    • Immunopathology of hyperacute xenograft rejection in a swine to primate model
    • PLATT JL, FISCHEL RJ, MATAS AJ, et al. Immunopathology of hyperacute xenograft rejection in a swine to primate model, transplantation 1991; 52: 514.
    • (1991) Transplantation , vol.52 , pp. 514
    • Platt, J.L.1    Fischel, R.J.2    Matas, A.J.3
  • 20
    • 0028272004 scopus 로고
    • Cytotoxic effects of human preformed anti-Gal IgG and complement on cultured pig cells
    • KOREN E, KUJUNDZIC M, KOSCEC M, et al. Cytotoxic effects of human preformed anti-Gal IgG and complement on cultured pig cells. Transplant Proc 1994; 26: 1336.
    • (1994) Transplant Proc , vol.26 , pp. 1336
    • Koren, E.1    Kujundzic, M.2    Koscec, M.3
  • 21
    • 0025264624 scopus 로고
    • Frameshift and non-sense mutations in a human genomic sequence homologous to a murine UDP-Gal:β-D-Gal(1,4)-D-G1cNAcα(1,3)-galactosyltransferase cDNA
    • LARSEN RD, RIVERA MC, ERNST LK, et al. Frameshift and non-sense mutations in a human genomic sequence homologous to a murine UDP-Gal:β-D-Gal(1,4)-D-G1cNAcα(1,3)-galactosyltransferase cDNA. J Biol Chem 1990; 265: 7055.
    • (1990) J Biol Chem , vol.265 , pp. 7055
    • Larsen, R.D.1    Rivera, M.C.2    Ernst, L.K.3
  • 22
    • 0025895390 scopus 로고
    • Characterization of an α1,3-galactosyltransferase homologue on human chromosome 12 that is organized as a processed pseudogene
    • JOZIASSE DH, SHAPER JH, JABS EW, et al. Characterization of an α1,3-galactosyltransferase homologue on human chromosome 12 that is organized as a processed pseudogene J Biol Chem 1991; 266: 6991.
    • (1991) J Biol Chem , vol.266 , pp. 6991
    • Joziasse, D.H.1    Shaper, J.H.2    Jabs, E.W.3
  • 23
    • 0001207979 scopus 로고
    • Suppression of α-galactosyl epitopes synthesis and production of the natural anti-Gal antibody: A major evolutionary event in ancestral Old World primates
    • GALILI U, ANDREWS P. Suppression of α-galactosyl epitopes synthesis and production of the natural anti-Gal antibody: a major evolutionary event in ancestral Old World primates. J Hum Evol 1995; 29: 433.
    • (1995) J Hum Evol , vol.29 , pp. 433
    • Galili, U.1    Andrews, P.2
  • 24
    • 0032530610 scopus 로고    scopus 로고
    • Discordant organ xenotransplantation in primates. World experience and current status
    • LAMBRIGTS D, SACHS DH, COOPER DKC. Discordant organ xenotransplantation in primates. World experience and current status. Tranplantation 1998; 66: 547.
    • (1998) Tranplantation , vol.66 , pp. 547
    • Lambrigts, D.1    Sachs, D.H.2    Cooper, D.K.C.3
  • 25
    • 0025804969 scopus 로고
    • Histopathology of hyperacute rejection of the heart: Experimental and clinical observations in allografts and xenografts
    • ROSE AG, COOPER DKC, HUMAN PA, et al. Histopathology of hyperacute rejection of the heart: experimental and clinical observations in allografts and xenografts. J Heart Lung Transplant 1991; 10: 223.
    • (1991) J Heart Lung Transplant , vol.10 , pp. 223
    • Rose, A.G.1    Cooper, D.K.C.2    Human, P.A.3
  • 26
    • 0023950859 scopus 로고
    • Effects of cyclosporine and antibody adsorption on pig cardiac xenograft survival in the baboon
    • COOPER DKC, HUMAN PA, LEXER G, et al. Effects of cyclosporine and antibody adsorption on pig cardiac xenograft survival in the baboon. J Heart Lung Transplant 1988; 7: 238.
    • (1988) J Heart Lung Transplant , vol.7 , pp. 238
    • Cooper, D.K.C.1    Human, P.A.2    Lexer, G.3
  • 27
    • 0000701630 scopus 로고
    • Plasmapheresis and splenectomy in experimental renal xenotransplantation
    • HARDY MA, ed. New York: , Elsevier
    • ALEXANDRE GPJ, GIANELLO P, LATINNE D, et al. Plasmapheresis and splenectomy in experimental renal xenotransplantation. In: HARDY MA, ed. Xenograft, 25. New York: , Elsevier, 1989.
    • (1989) Xenograft , vol.25
    • Alexandre, G.P.J.1    Gianello, P.2    Latinne, D.3
  • 28
    • 0029175941 scopus 로고
    • Xenotransplantation of pig kidneys to nonhuman primates. I. Development of the model
    • SABLINSKI T, LATINNE D, GIANELLO P, et al. Xenotransplantation of pig kidneys to nonhuman primates. I. Development of the model. Xeno-transplantation 1995; 2: 264.
    • (1995) Xeno-transplantation , vol.2 , pp. 264
    • Sablinski, T.1    Latinne, D.2    Gianello, P.3
  • 29
    • 0002266212 scopus 로고    scopus 로고
    • Extracorporeal immunoadsorption of anti- Pig antibody in pigs using αGal oligosaccharide immunoaffinity columns
    • COOPER DKC, CAIRNS TDH, TAUBE DH. Extracorporeal immunoadsorption of anti-pig antibody in pigs using αGal oligosaccharide immunoaffinity columns. Xenotransplantation 1996; 4: 27.
    • (1996) Xenotransplantation , vol.4 , pp. 27
    • Cooper, D.K.C.1    Cairns, T.D.H.2    Taube, D.H.3
  • 30
    • 0028855110 scopus 로고
    • Absence of hyperacute rejection in newborn pig-to-baboon cardiac xenografts
    • KAPLON RJ, MICHLER RE, XU H, et al. Absence of hyperacute rejection in newborn pig-to-baboon cardiac xenografts. Transplantation 1994; 59: 1.
    • (1994) Transplantation , vol.59 , pp. 1
    • Kaplon, R.J.1    Michler, R.E.2    Xu, H.3
  • 31
    • 0029039406 scopus 로고
    • Cardiac xenografts between primate species provide evidence for the importance of the α-galactosyl determinant in hyperacute rejection
    • COLLINS BH, COTTERELL AH, MCCURRY KR, et al. Cardiac xenografts between primate species provide evidence for the importance of the α-galactosyl determinant in hyperacute rejection J Immunol 1995; 154: 5500.
    • (1995) J Immunol , vol.154 , pp. 5500
    • Collins, B.H.1    Cotterell, A.H.2    Mccurry, K.R.3
  • 32
    • 0027480563 scopus 로고
    • Prolongation of cardiac xenograft survival by depletion of complement
    • LEVENTHAL JR, DALMASSO AP, CROMWELL JW, et al. Prolongation of cardiac xenograft survival by depletion of complement. Transplantation 1993; 55: 857.
    • (1993) Transplantation , vol.55 , pp. 857
    • Leventhal, J.R.1    Dalmasso, A.P.2    Cromwell, J.W.3
  • 33
    • 0030661679 scopus 로고    scopus 로고
    • Delayed xenograft rejection of pig- To-baboon cardiac transplants after cobra venom factor therapy
    • KOBAYASHI T, TANIGUCHI S, NEETHLING FA, et al. Delayed xenograft rejection of pig-to-baboon cardiac transplants after cobra venom factor therapy Transplantation 1997; 64: 1255.
    • (1997) Transplantation , vol.64 , pp. 1255
    • Kobayashi, T.1    Taniguchi, S.2    Neethling, F.A.3
  • 34
    • 0029068597 scopus 로고
    • The generation of transgenic pigs as potential organ donors for humans
    • COZZI E, WHITE DJG. The generation of transgenic pigs as potential organ donors for humans. Nature Med 1995; 1: 964.
    • (1995) Nature Med , vol.1 , pp. 964
    • Cozzi, E.1    White, D.J.G.2
  • 35
    • 0029033071 scopus 로고
    • Human complement regulatory proteins protect swine to primate cardiac xenografts from human injury
    • MCCURRY KR, KOOYMAN DL, ALVARADO CG, et al. Human complement regulatory proteins protect swine to primate cardiac xenografts from human injury. Nature Med 1995; 1: 123.
    • (1995) Nature Med , vol.1 , pp. 123
    • Mccurry, K.R.1    Kooyman, D.L.2    Alvarado, C.G.3
  • 36
    • 0032572261 scopus 로고    scopus 로고
    • Orthotopic heart transplantation in a transgenic pig-to-primate model
    • SCHMOECKEL M, BHATTI FN, ZAIDI A, et al. Orthotopic heart transplantation in a transgenic pig-to-primate model. Transplantation 1998; 65: 1570.
    • (1998) Transplantation , vol.65 , pp. 1570
    • Schmoeckel, M.1    Bhatti, F.N.2    Zaidi, A.3
  • 37
    • 0032572281 scopus 로고    scopus 로고
    • Life-supporting pig-to-primate renal xenotransplantation using genetically modified donors
    • ZAIDI A, SCHMOECKEL M, BHATTI F, et al. Life-supporting pig-to-primate renal xenotransplantation using genetically modified donors Transplantation 1998; 65: 1584.
    • (1998) Transplantation , vol.65 , pp. 1584
    • Zaidi, A.1    Schmoeckel, M.2    Bhatti, F.3
  • 38
    • 0032558089 scopus 로고    scopus 로고
    • Anti-Gala1-3Gal antibody response to porcine bone marrow in unmodified baboons and baboons conditioned for tolerance induction
    • KOZLOWSKI T, MONROY R, XU Y, et al. Anti-Gala1-3Gal antibody response to porcine bone marrow in unmodified baboons and baboons conditioned for tolerance induction. Transplantation 1998; 66: 176.
    • (1998) Transplantation , vol.66 , pp. 176
    • Kozlowski, T.1    Monroy, R.2    Xu, Y.3
  • 39
    • 0033556459 scopus 로고    scopus 로고
    • Porcine kidney and heart transplantation in baboons undergoing a tolerance inducing regimen and antibody adsorption
    • KOZLOWSKI T, SHIMIZU A, LAMBRIGTS D, et al. Porcine kidney and heart transplantation in baboons undergoing a tolerance inducing regimen and antibody adsorption. Transplantation 1999; 67: 18.
    • (1999) Transplantation , vol.67 , pp. 18
    • Kozlowski, T.1    Shimizu, A.2    Lambrigts, D.3
  • 41
    • 0030980701 scopus 로고    scopus 로고
    • Porcine and bovine cartilage transplants in cynomolgus monkeys: II. Changes in anti-gal response during chronic rejection
    • GALILI U, LATEMPLE DC, WALGENBACH AW, et al. Porcine and bovine cartilage transplants in cynomolgus monkeys: II. Changes in anti-gal response during chronic rejection. Transplantation 1997; 63: 646.
    • (1997) Transplantation , vol.63 , pp. 646
    • Galili, U.1    Latemple, D.C.2    Walgenbach, A.W.3
  • 42
    • 0003105441 scopus 로고    scopus 로고
    • Mechanisms of delayed xenograft rejection
    • COOPER DKC, KEMP E, PLATT JL, WHITE DJG, eds. Heidelberg: Springer
    • GOODMAN DL, MILLAN MT, FERRAN C, et al. Mechanisms of delayed xenograft rejection. In: COOPER DKC, KEMP E, PLATT JL, WHITE DJG, eds. Xenotransplantation, 2nd edn. Heidelberg: Springer, 1997.
    • (1997) Xenotransplantation, 2nd Edn.
    • Goodman, D.L.1    Millan, M.T.2    Ferran, C.3
  • 44
    • 0023605768 scopus 로고
    • ABO incompatible renal transplantation: Initial immunopathologic evaluation
    • CHOPEK MW, SIMMONS RL, PLATT JL. ABO incompatible renal transplantation: initial immunopathologic evaluation. Transplant Proc 1987; 19: 4553.
    • (1987) Transplant Proc , vol.19 , pp. 4553
    • Chopek, M.W.1    Simmons, R.L.2    Platt, J.L.3
  • 45
    • 0023576832 scopus 로고
    • Present experiences in a series of 26 ABO-incompatible living donor renal allografts
    • ALEXANDRE GPJ, SQUIFFLET JP, DE BRUYERE M, et al. Present experiences in a series of 26 ABO-incompatible living donor renal allografts. Transplant Proc 1987; 19: 4538.
    • (1987) Transplant Proc , vol.19 , pp. 4538
    • Alexandre, G.P.J.1    Squifflet, J.P.2    De Bruyere, M.3
  • 46
    • 0024574794 scopus 로고
    • Removal of HLA antibodies by extracorporeal immunoadsorption to enable renal transplantation
    • PALMER A, WELSH K, GJORSTRUP P, et al. Removal of HLA antibodies by extracorporeal immunoadsorption to enable renal transplantation. Lancet 1989; 1: 10.
    • (1989) Lancet , vol.1 , pp. 10
    • Palmer, A.1    Welsh, K.2    Gjorstrup, P.3
  • 47
    • 0002426585 scopus 로고
    • Accommodation -the role of natural antibody and complement in discordant xenograft rejection
    • COOPER DKC, KEMP E, REEMTSMA K, WHITE DJG, eds. Heidelberg: Springer
    • BACH FH, PLATT JL, COOPER DKC. Accommodation -the role of natural antibody and complement in discordant xenograft rejection. In: COOPER DKC, KEMP E, REEMTSMA K, WHITE DJG, eds. Xenotransplantation, 1st edn. Heidelberg: Springer, 1991.
    • (1991) Xenotransplantation, 1st Edn.
    • Bach, F.H.1    Platt, J.L.2    Cooper, D.K.C.3
  • 48
    • 16944366395 scopus 로고    scopus 로고
    • Accommodation of vascularized xenografts: Expression of "protective genes" by donor endothelial cells in a host Th2 cytokine environment
    • BACH FH, FERRAN C, HECHENLEITNER P, et al. Accommodation of vascularized xenografts: expression of "protective genes" by donor endothelial cells in a host Th2 cytokine environment. Nature Med 1997; 3: 196.
    • (1997) Nature Med , vol.3 , pp. 196
    • Bach, F.H.1    Ferran, C.2    Hechenleitner, P.3
  • 49
    • 0002326105 scopus 로고    scopus 로고
    • Xenogeneic tolerance through hematopoietic cell and thymic transplantation
    • COOPER DKC, KEMP E, PLATT JL, WHITE DJG, eds. Heidelberg: Springer
    • SYKES M, SACHS DH. Xenogeneic tolerance through hematopoietic cell and thymic transplantation. In: COOPER DKC, KEMP E, PLATT JL, WHITE DJG, eds. Xenotransplantation, 2nd edn. Heidelberg: Springer, 1997.
    • (1997) Xenotransplantation, 2nd Edn.
    • Sykes, M.1    Sachs, D.H.2
  • 50
    • 0015036679 scopus 로고
    • Prolongation of renal xenografts by the simultaneous sequestration of preformed antibody, inhibition of complement, coagulation, and antibody synthesis
    • MOBERG AW, SHONS AR, GERWURZ H, et al. Prolongation of renal xenografts by the simultaneous sequestration of preformed antibody, inhibition of complement, coagulation, and antibody synthesis. Transplant Proc 1971; 3: 538.
    • (1971) Transplant Proc , vol.3 , pp. 538
    • Moberg, A.W.1    Shons, A.R.2    Gerwurz, H.3
  • 51
    • 0015036274 scopus 로고
    • Effect of heparin, arvin, liver perfusion, and heterologous anti-platelet serum on rejection of pig kidney to dog
    • SLAPAK M, GREENBAUM M, BARDAWIL W, et al. Effect of heparin, arvin, liver perfusion, and heterologous anti-platelet serum on rejection of pig kidney to dog. Transplant Proc 1971; 3: 558.
    • (1971) Transplant Proc , vol.3 , pp. 558
    • Slapak, M.1    Greenbaum, M.2    Bardawil, W.3
  • 52
    • 0015535633 scopus 로고
    • Techniques of in vivo plasma modification for the treatment of hyperacute rejection
    • SHONS AR, BEIR M, JETZER J, et al. Techniques of in vivo plasma modification for the treatment of hyperacute rejection. Surgery 1973; 73: 28.
    • (1973) Surgery , vol.73 , pp. 28
    • Shons, A.R.1    Beir, M.2    Jetzer, J.3
  • 53
    • 0018287872 scopus 로고
    • Modification of hyperacute renal xenograft rejection after extracorporeal immunoadsorption of heterospecific antibody
    • TERMAN DS, GARCIA-RINALDI R, MCCALMON R, et al. Modification of hyperacute renal xenograft rejection after extracorporeal immunoadsorption of heterospecific antibody. Int J Artif Organs 1979; 2: 35.
    • (1979) Int J Artif Organs , vol.2 , pp. 35
    • Terman, D.S.1    Garcia-Rinaldi, R.2    Mccalmon, R.3
  • 54
    • 0022884461 scopus 로고
    • Hyperacute rejection in a discordant (pig-to-baboon) cardiac xenograft model
    • LEXER G, COOPER DKC, ROSE AG, et al. Hyperacute rejection in a discordant (pig-to-baboon) cardiac xenograft model. J Heart Transplant 1986; 5: 411.
    • (1986) J Heart Transplant , vol.5 , pp. 411
    • Lexer, G.1    Cooper, D.K.C.2    Rose, A.G.3
  • 55
    • 0032029920 scopus 로고    scopus 로고
    • Removal of primate xenoreactive natural antibodies by extracorporeal perfusion of pig kidneys and livers
    • AZIMZADEH A, MEYER C, WATIER H, et al. Removal of primate xenoreactive natural antibodies by extracorporeal perfusion of pig kidneys and livers. Transplant Immunol 1998; 1: 13.
    • (1998) Transplant Immunol , vol.1 , pp. 13
    • Azimzadeh, A.1    Meyer, C.2    Watier, H.3
  • 56
    • 18244419906 scopus 로고    scopus 로고
    • Evidence of human non-alpha- Galactosyl antibodies involved in the hyperacute rejection of pig lungs and their removal by pig organ perfusion
    • MACCHIARINI P, ORIOL R, AZIMZADEH A, et al. Evidence of human non-alpha-galactosyl antibodies involved in the hyperacute rejection of pig lungs and their removal by pig organ perfusion. J Thorac Cardiovasc Surg 1998; 5: 831.
    • (1998) J Thorac Cardiovasc Surg , vol.5 , pp. 831
    • Macchiarini, P.1    Oriol, R.2    Azimzadeh, A.3
  • 57
    • 0028058874 scopus 로고
    • Evidence that intravenously administered alpha-galactosyl carbohydrates reduce baboon serum cytotoxicity to pig kidney cells (PK15): And transplanted pig hearts
    • YE Y, NEETHLING FA, NIEKRASZ M, et al. Evidence that intravenously administered alpha-galactosyl carbohydrates reduce baboon serum cytotoxicity to pig kidney cells (PK15): and transplanted pig hearts. Transplantation 1994; 58: 330.
    • (1994) Transplantation , vol.58 , pp. 330
    • Ye, Y.1    Neethling, F.A.2    Niekrasz, M.3
  • 58
    • 2442758069 scopus 로고    scopus 로고
    • In vivo immunoadsorption of antipig antibodies in baboons using a specific Galα1-3Gal column
    • TANIGUCHI S, NEETHLING FA, KORCHAGINA EY, et al. In vivo immunoadsorption of antipig antibodies in baboons using a specific Galα1-3Gal column. Transplantation 1996; 10: 1: 379.
    • (1996) Transplantation , vol.10 , Issue.1 , pp. 379
    • Taniguchi, S.1    Neethling, F.A.2    Korchagina, E.Y.3
  • 59
    • 0032570299 scopus 로고    scopus 로고
    • Removal of anti-porcine natural antibodies from huma and nonhuman primate plasma 111 vitro and in vivo by a Galα1-3Galb1-4G1c-X immunoaffinity column
    • XU Y, LORF T, SABLINSKI T, et al. Removal of anti-porcine natural antibodies from huma and nonhuman primate plasma 111 vitro and in vivo by a Galα1-3Galb1-4G1c-X immunoaffinity column. Transplantation 1998; 65: 172.
    • (1998) Transplantation , vol.65 , pp. 172
    • Xu, Y.1    Lorf, T.2    Sablinski, T.3
  • 60
    • 13144276329 scopus 로고    scopus 로고
    • Depletion of anti-αGal1-3Gal antibody in baboons by specific immunoaffinity columns
    • KOZLOWSKI T, IERINO FL, LAMBRIGTS D, et al. Depletion of anti-αGal1-3Gal antibody in baboons by specific immunoaffinity columns. Xenotransplantation 1998; 5: 122.
    • (1998) Xenotransplantation , vol.5 , pp. 122
    • Kozlowski, T.1    Ierino, F.L.2    Lambrigts, D.3
  • 61
    • 0029742923 scopus 로고    scopus 로고
    • Monoclonal antiidiotypic antibodies neutralize cytotoxic effects of anti-αGal antibodies
    • KOREN E, MILOTIC F, NEETHLING FA, et al. Monoclonal antiidiotypic antibodies neutralize cytotoxic effects of anti-αGal antibodies. Transplantation 1996; 62: 837.
    • (1996) Transplantation , vol.62 , pp. 837
    • Koren, E.1    Milotic, F.2    Neethling, F.A.3
  • 62
    • 0025822946 scopus 로고
    • Use of intravenous immune globulin therapy: An overview
    • WORDELL CJ. Use of intravenous immune globulin therapy: an overview. DICP 1991; 25: 805.
    • (1991) DICP , vol.25 , pp. 805
    • Wordell, C.J.1
  • 63
    • 0032057037 scopus 로고    scopus 로고
    • Immunomodulatory actions of intravenous immunoglobulin (IVIG): Potential applications in solid organ transplant recipients
    • JORDAN SC, TYAN D, CZER L, et al. Immunomodulatory actions of intravenous immunoglobulin (IVIG): potential applications in solid organ transplant recipients. Pediatr Transplant 1998; 2: 92.
    • (1998) Pediatr Transplant , vol.2 , pp. 92
    • Jordan, S.C.1    Tyan, D.2    Czer, L.3
  • 64
    • 0028817015 scopus 로고
    • Immunoglobulin prevents complement mediated hyperacute rejection in swine-to-primate xenotransplantation
    • MAGEE JC, COLLINS BH, HARLAND RC, et al. Immunoglobulin prevents complement mediated hyperacute rejection in swine-to-primate xenotransplantation. J Clin Invest 1995; 96: 2404.
    • (1995) J Clin Invest , vol.96 , pp. 2404
    • Magee, J.C.1    Collins, B.H.2    Harland, R.C.3
  • 65
    • 0033590571 scopus 로고    scopus 로고
    • Mechanism of intravenous immune globulin therapy in antibody-mediated autoimmune diseases
    • YU Z, LENNON VA. Mechanism of intravenous immune globulin therapy in antibody-mediated autoimmune diseases. N Engl J Med 1999; 340: 227.
    • (1999) N Engl J Med , vol.340 , pp. 227
    • Yu, Z.1    Lennon, V.A.2
  • 66
    • 0030062283 scopus 로고    scopus 로고
    • The reducing end of αGal oligosaccharides contributes to their efficiency in blocking natural antibodies of human and baboon sera
    • NEETHLING FA, JOZIASSE D, BOVIN N, et al. The reducing end of αGal oligosaccharides contributes to their efficiency in blocking natural antibodies of human and baboon sera. Transplant Int 1996; 9: 98.
    • (1996) Transplant Int , vol.9 , pp. 98
    • Neethling, F.A.1    Joziasse, D.2    Bovin, N.3
  • 67
    • 0032518991 scopus 로고    scopus 로고
    • Intravenous infusion of αGal oligosaccharides in baboons delays hyperacute rejection of porcine heart xenografts
    • SIMON PM, NEETHLING FA, TANIGUCHI S, et al. Intravenous infusion of αGal oligosaccharides in baboons delays hyperacute rejection of porcine heart xenografts. Transplantation 1998; 63: 346.
    • (1998) Transplantation , vol.63 , pp. 346
    • Simon, P.M.1    Neethling, F.A.2    Taniguchi, S.3
  • 68
    • 0032587273 scopus 로고    scopus 로고
    • Intravenous synthetic αGal saccharides delay hyperacute rejection following pig-to-baboon heart transplantation
    • ROMANO E, NEETHLING FA, NILSSON KGI, et al. Intravenous synthetic αGal saccharides delay hyperacute rejection following pig-to-baboon heart transplantation Xenotransplantation 1996; 6: 36.
    • (1996) Xenotransplantation , vol.6 , pp. 36
    • Romano, E.1    Neethling, F.A.2    Nilsson, K.G.I.3
  • 69
    • 0031903880 scopus 로고    scopus 로고
    • Total body irradiation for marrow or stem-cell transplantation
    • LINDSLEY K, DEEG HJ. Total body irradiation for marrow or stem-cell transplantation. Cancer Invest 1998; 16: 424.
    • (1998) Cancer Invest , vol.16 , pp. 424
    • Lindsley, K.1    Deeg, H.J.2
  • 70
    • 0031003730 scopus 로고    scopus 로고
    • Mixed chimerism and transplantation tolerance induced by a nonlethal preparative regimen in cynomolgus monkeys
    • KIMIKAWA M, KAWAI T, SACHS DH, et al. Mixed chimerism and transplantation tolerance induced by a nonlethal preparative regimen in cynomolgus monkeys Transplant Proc 1997; 29: 1218.
    • (1997) Transplant Proc , vol.29 , pp. 1218
    • Kimikawa, M.1    Kawai, T.2    Sachs, D.H.3
  • 71
    • 0028858187 scopus 로고
    • Multicolor flow cytometry analysis of blood cell subsets in patients given total body irradiation before bone marrow transplantation
    • CLAVE E, SOCIE G, COSSET JM. Multicolor flow cytometry analysis of blood cell subsets in patients given total body irradiation before bone marrow transplantation. Int J Radiat Oncol Biol Phys 1995; 34: 881.
    • (1995) Int J Radiat Oncol Biol Phys , vol.34 , pp. 881
    • Clave, E.1    Socie, G.2    Cosset, J.M.3
  • 72
    • 0032414777 scopus 로고    scopus 로고
    • Pharmacologic immunosuppressive therapy and extracorporeal immunoadsorption in the suppression of anti-αGal antibody in the baboon
    • LAMBRIGTS D, VAN CALSTER P, Xu Y, et al. Pharmacologic immunosuppressive therapy and extracorporeal immunoadsorption in the suppression of anti-αGal antibody in the baboon. Xenotransplantation 1998; 5: 274.
    • (1998) Xenotransplantation , vol.5 , pp. 274
    • Lambrigts, D.1    Van Calster, P.2    Xu, Y.3
  • 73
    • 0031978140 scopus 로고    scopus 로고
    • Triple immunosuppression reduces mononuclear cell infiltration and prolongs graft life in pig-to-newborn baboon cardiac xenotransplantation
    • MINANOV OP, ARTRIP JH, SZABOLCS M, et al. Triple immunosuppression reduces mononuclear cell infiltration and prolongs graft life in pig-to-newborn baboon cardiac xenotransplantation. J Thorac Cardiovasc Surg 1998; 115: 998.
    • (1998) J Thorac Cardiovasc Surg , vol.115 , pp. 998
    • Minanov, O.P.1    Artrip, J.H.2    Szabolcs, M.3
  • 74
    • 0032995701 scopus 로고    scopus 로고
    • Long-term prognosis following zidovudine monotherapy in primary human immunodeficiency virus type 1 infection
    • LINDBACK S, VIZZARD J, COOPER DA, et al. Long-term prognosis following zidovudine monotherapy in primary human immunodeficiency virus type 1 infection. J Infect Dis 1999; 179: 1549.
    • (1999) J Infect Dis , vol.179 , pp. 1549
    • Lindback, S.1    Vizzard, J.2    Cooper, D.A.3
  • 75
    • 0004459676 scopus 로고
    • Reversal of recalcitrant cardiac allograft rejection with methotrexate
    • COSTANZO-NORDIN M, GRUSK B, SILVER M, et al Reversal of recalcitrant cardiac allograft rejection with methotrexate. Circulation 1988; 78: 47.
    • (1988) Circulation , vol.78 , pp. 47
    • Costanzo-Nordin, M.1    Grusk, B.2    Silver, M.3
  • 76
    • 0027433354 scopus 로고
    • Cladribine, 2-chloro-deoxyadenosine (CDA): An inhibitor of human B and T cell activation in vitro
    • GORSKI A, GRIEB P, KORCZAK-KOWALSKA G, et al. Cladribine, 2-chloro-deoxyadenosine (CDA): an inhibitor of human B and T cell activation in vitro. Immunopharmacology 1993; 26: 197.
    • (1993) Immunopharmacology , vol.26 , pp. 197
    • Gorski, A.1    Grieb, P.2    Korczak-Kowalska, G.3
  • 77
    • 0028057250 scopus 로고
    • Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20
    • REFF ME, CARNER K, CHAMBERS KS, et al. Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20. Blood 1994; 83: 435.
    • (1994) Blood , vol.83 , pp. 435
    • Reff, M.E.1    Carner, K.2    Chambers, K.S.3
  • 78
    • 17144455839 scopus 로고    scopus 로고
    • IDEC-C2B8 results of a phase I multiple-dose trial in patients with relapsed non-Hodgkin's lymphoma
    • MALONEY DG, GRILLO-LOPEZ AJ, BODKIN DJ, et al. IDEC-C2B8 results of a phase I multiple-dose trial in patients with relapsed non-Hodgkin's lymphoma. J Clin Oncol 1997; 15: 3266.
    • (1997) J Clin Oncol , vol.15 , pp. 3266
    • Maloney, D.G.1    Grillo-Lopez, A.J.2    Bodkin, D.J.3
  • 79
    • 7144250528 scopus 로고    scopus 로고
    • Feasibility and pharmacokinitic study of a chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in relapsed B cell lymphoma
    • The IDEC-C2B8 study group
    • TOBINAI K, KOBAYASHI Y, NARABAYASHI M, et al. Feasibility and pharmacokinitic study of a chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in relapsed B cell lymphoma. The IDEC-C2B8 study group. Ann Oncol 1998; 9: 527.
    • (1998) Ann Oncol , vol.9 , pp. 527
    • Tobinai, K.1    Kobayashi, Y.2    Narabayashi, M.3
  • 80
    • 0032530342 scopus 로고    scopus 로고
    • Rituximab (anti-CD20 monoclonal antibody) for the treatment of patients with relapsing or refractory aggressive lymphoma: A multicenter phase II study
    • COIFFIER B, HAIOUN C, KETTERER N, et al. Rituximab (anti-CD20 monoclonal antibody) for the treatment of patients with relapsing or refractory aggressive lymphoma: a multicenter phase II study. Blood 1998; 92: 1927.
    • (1998) Blood , vol.92 , pp. 1927
    • Coiffier, B.1    Haioun, C.2    Ketterer, N.3
  • 81
    • 0345337254 scopus 로고    scopus 로고
    • Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: Half of patients respond to a four dose treatment program
    • MCLAUGHLIN P, GRILLO-LOPEZ AJ, LINK BK, et al. Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four dose treatment program. J Clin Oncol 1998; 16: 2825.
    • (1998) J Clin Oncol , vol.16 , pp. 2825
    • Mclaughlin, P.1    Grillo-Lopez, A.J.2    Link, B.K.3
  • 82
    • 0031980763 scopus 로고    scopus 로고
    • Evaluation of immunotoxin containing single-chain ribosome-inactivating proteins and an anti-CD22 monoclonal antibody (OM124): In vitro and in vivo studies
    • BOLOGNESSI A, TAZZARI PL, OLIVIERI F, et al. Evaluation of immunotoxin containing single-chain ribosome-inactivating proteins and an anti-CD22 monoclonal antibody (OM124): in vitro and in vivo studies. Br J Haematol 1998; 101: 179.
    • (1998) Br J Haematol , vol.101 , pp. 179
    • Bolognessi, A.1    Tazzari, P.L.2    Olivieri, F.3
  • 83
    • 0029056665 scopus 로고
    • Continuous infusion of the anti-CD22 immunotoxin IgG-RFB4-SMPT-dga in patients with B cell lymphoma: A phase I study
    • SAUSVILLE EA, HEADLEE D, STETLER-STEVENSON M, et al. Continuous infusion of the anti-CD22 immunotoxin IgG-RFB4-SMPT-dgA in patients with B cell lymphoma: a phase I study. Blood 1995; 85: 3457.
    • (1995) Blood , vol.85 , pp. 3457
    • Sausville, E.A.1    Headlee, D.2    Stetler-Stevenson, M.3
  • 84
    • 0030993376 scopus 로고    scopus 로고
    • CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling
    • TEDDER TF, TUSCANO J, SATO S, et al. CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling. Annu Rev Immunol 1997; 15: 481.
    • (1997) Annu Rev Immunol , vol.15 , pp. 481
    • Tedder, T.F.1    Tuscano, J.2    Sato, S.3
  • 85
    • 0026528181 scopus 로고
    • Molecular and biological characterization of a murine ligand for CD40
    • ARMITAGE RJ, FANSLOW WC, STROCKBINE L, et al. Molecular and biological characterization of a murine ligand for CD40. Nature 1992; 357: 80.
    • (1992) Nature , vol.357 , pp. 80
    • Armitage, R.J.1    Fanslow, W.C.2    Strockbine, L.3
  • 86
    • 0026772133 scopus 로고
    • A 39-kDa protein on activated helper T cells binds CD40and transduces the signal for cognate activation of B cells
    • NOELLE R, ROY M, SHEPHERD D, et al. A 39-kDa protein on activated helper T cells binds CD40and transduces the signal for cognate activation of B cells. Proc Natl Acad Sci USA 1992; 89: 6550.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6550
    • Noelle, R.1    Roy, M.2    Shepherd, D.3
  • 87
    • 15844404353 scopus 로고    scopus 로고
    • Long-term acceptance of skin and cardiac allografts after blocking CD40 ligand
    • LARSEN CP, ELWOOD ET, ALEXANDER DZ, et al. Long-term acceptance of skin and cardiac allografts after blocking CD40 ligand. Nature 1996; 381: 434.
    • (1996) Nature , vol.381 , pp. 434
    • Larsen, C.P.1    Elwood, E.T.2    Alexander, D.Z.3
  • 88
    • 12644262358 scopus 로고    scopus 로고
    • CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates
    • KIRK AD, HARLAN DM, ARMSTRONG NN, et al. CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates. Proc Natl Acad Sci USA 1997; 94: 8789.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8789
    • Kirk, A.D.1    Harlan, D.M.2    Armstrong, N.N.3
  • 89
    • 0032526283 scopus 로고    scopus 로고
    • Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance
    • WEKERLE T, SAYEGH MH, HILL J, et al. Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance. J Exp Med 1998; 187: 2037.
    • (1998) J Exp Med , vol.187 , pp. 2037
    • Wekerle, T.1    Sayegh, M.H.2    Hill, J.3
  • 90
    • 0032526076 scopus 로고    scopus 로고
    • Prolonged acceptance of concordant and discordant xenografts with combined CD40 and CD28 pathway blockade
    • ELWOOD ET, LARSEN CP, CHO HR, et al. Prolonged acceptance of concordant and discordant xenografts with combined CD40 and CD28 pathway blockade. Transplantation 1998; 65: 1422.
    • (1998) Transplantation , vol.65 , pp. 1422
    • Elwood, E.T.1    Larsen, C.P.2    Cho, H.R.3
  • 92
    • 0029730751 scopus 로고    scopus 로고
    • Simultaneous expression by porcine aorta endothelial cells of glycosphingolipids bearing the major epitope for human xenoreactive antibodies (Galα1-3Gal), blood group H determinant and N-glycolylneuraminic acid
    • BOUHOURS D, POURCEL C, BOUHOURS JF. Simultaneous expression by porcine aorta endothelial cells of glycosphingolipids bearing the major epitope for human xenoreactive antibodies (Galα1-3Gal), blood group H determinant and N-glycolylneuraminic acid. Glycoconjugate J. 1996; 13: 947.
    • (1996) Glycoconjugate J. , vol.13 , pp. 947
    • Bouhours, D.1    Pourcel, C.2    Bouhours, J.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.