Suppression of Natural and Elicited Antibodies in Pig-to-Baboon Heart Transplantation Using a Human Anti-Human CD154 mAb-Based Regimen

American Journal of Transplantation

Volumn 4, Issue 3, 2004, Pages 363-372

  Kuwaki, Kenji ^a   Knosalla, Christoph ^a   Dor, Frank J M F ^a   Gollackner, Bernd ^a   Tseng, Yau Lin ^a   Houser, Stuart ^a   Mueller, Nicolas ^a   Prabharasuth, Derek ^a   Alt, Amy ^b   Moran, Kathy ^b   Cheng, Jane ^b   Behdad, Amir ^c   Sachs, David H ^a   Fishman, Jay A ^a   Schuurman, Henk Jan ^b   Awwad, Michel ^b   Cooper, David K C ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Immerge Biotherapeutics Inc   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Anti CD154 monoclonal antibody; Anti Gal antibody; Baboon; Costimulatory blockade; Heart transplantation; Pig; Xenotransplantation

Indexed keywords

CD40 LIGAND MONOCLONAL ANTIBODY; CIMETIDINE; COBROTOXIN; COMPLEMENT COMPONENT C3B RECEPTOR; DECAY ACCELERATING FACTOR; ERYTHROPOIETIN; GALACTOSYLGALACTOSE; GALACTOSYLGALACTOSE ANTIBODY; GANCICLOVIR; GLYCOCONJUGATE; HEPARIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LEVOFLOXACIN; LOCD2B; METHYLPREDNISOLONE; MONOCLONAL ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PROSTACYCLIN; PROTEIN ANTIBODY; T CELL MONOCLONAL ANTIBODY; THYMOCYTE ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; BABOON; CELL INFILTRATION; CONTROLLED STUDY; DEATH; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DOSE REGIMEN; DRUG HALF LIFE; GRAFT FAILURE; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; HETEROTOPIC TRANSPLANTATION; IMMUNOSUPPRESSIVE TREATMENT; IRRADIATION; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; SWINE; THROMBOSIS; THROMBOTIC THROMBOCYTOPENIC PURPURA; THYMUS; XENOGRAFT;

ANIMALS; ANTIBODIES, MONOCLONAL; CD40 LIGAND; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; IMMUNOSUPPRESSIVE AGENTS; MYOCARDIUM; PAPIO; SWINE; TIME FACTORS; TRANSPLANTATION, HETEROLOGOUS;

EID: 10744228498     PISSN: 16006135     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2004.00353.x     Document Type: Article

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