Structure-permeability relationship analysis of the permeation barrier properties of the stratum corneum and viable epidermis/dermis of rat skin

Journal of Pharmaceutical Sciences

Volumn 97, Issue 10, 2008, Pages 4391-4403

  Yamaguchi, Koji ^a   Mitsui, Tetsuya ^a   Aso, Yoshinori ^a   Sugibayashi, Kenji ^b  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^b JOSAI UNIVERSITY   (Japan)

Author keywords

Diffusion; Mathematical models; Permeability; Rat; Simulations; Skin; Stratum corneum; Viable epidermis and dermis

Indexed keywords

OCTANOL; WATER;

ANIMAL TISSUE; ARTICLE; DERMIS; DIFFUSION COEFFICIENT; DRUG PENETRATION; EPIDERMIS; HYDROGEN BOND; LIPOPHILICITY; MALE; NONHUMAN; PARTITION COEFFICIENT; PHYSICAL CHEMISTRY; RAT; SIMULATION; SKIN PENETRATION; STRATUM CORNEUM; THICKNESS;

EID: 55749105385     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21330     Document Type: Article

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