Correlation between the transdermal permeation of ketoprofen and its solubility in mixtures of a pH 6.5 phosphate buffer and various solvents

Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents

Volumn 9, Issue 1, 2002, Pages 39-45

  Ceschel, G C ^a   Maffei, P ^a   Borgia, S Lombardi ^a  

^a Pharmaceutical Sciences Department   (Italy)

Author keywords

Diffusion Constant; Ketoprofen; Partition Coefficient; Permeability; Transdermal Permeation

Indexed keywords

2 PROPANOL; ALCOHOL; BUFFER; DIETHYLENE GLYCOL MONOETHYL ETHER; GLYCEROL; KETOPROFEN; MACROGOL 400; PHOSPHATE; PROPYLENE GLYCOL; SOLVENT;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIFFUSION COEFFICIENT; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG FORMULATION; DRUG PENETRATION; DRUG SOLUBILITY; GEL; IN VITRO STUDY; MALE; NONHUMAN; PARTITION COEFFICIENT; PH; PRIORITY JOURNAL; STRATUM CORNEUM; SWINE;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BIOLOGICAL TRANSPORT; BUFFERS; CELL MEMBRANE PERMEABILITY; DELAYED-ACTION PREPARATIONS; DIFFUSION; HYDROGEN-ION CONCENTRATION; KETOPROFEN; MALE; PERMEABILITY; PHOSPHATES; SKIN; SOLUBILITY; SWINE; TIME FACTORS; VEHICLES;

EID: 0036183230     PISSN: 10717544     EISSN: None     Source Type: Journal    
DOI: 10.1080/107175402753413163     Document Type: Article

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