Analysis of in vitro skin permeation of 22-oxacalcitriol from ointments based on a two- or three-layer diffusion model considering diffusivity in a vehicle

International Journal of Pharmaceutics

Volumn 336, Issue 2, 2007, Pages 310-318

  Yamaguchi, Koji ^a   Mitsui, Tetsuya ^a   Aso, Yoshinori ^a   Sugibayashi, Kenji ^b  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^b JOSAI UNIVERSITY   (Japan)

Author keywords

Diffusion model; Formulation; In vitro rat skin; Partition; Skin permeation

Indexed keywords

22 OXACALCITRIOL; DRUG VEHICLE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIFFUSION; DIFFUSION COEFFICIENT; DRUG DOSAGE FORM; IN VITRO STUDY; NONHUMAN; OINTMENT; PRIORITY JOURNAL; RAT; SKINFOLD THICKNESS; STRATUM CORNEUM;

ADMINISTRATION, CUTANEOUS; ANIMALS; CALCITRIOL; DERMATOLOGIC AGENTS; DIFFUSION; MALE; MODELS, BIOLOGICAL; OINTMENT BASES; OINTMENTS; PERMEABILITY; RATS; RATS, SPRAGUE-DAWLEY; SKIN; SKIN ABSORPTION; TRIGLYCERIDES;

EID: 34247607622     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.12.017     Document Type: Article

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