Epidermal permeability-penetrant structure relationships: 4, QSAR of permeant diffusion across human stratum corneum in terms of molecular weight, H-bonding and electronic charge

International Journal of Pharmaceutics

Volumn 197, Issue 1-2, 2000, Pages 203-211

  Pugh, W John ^a   Degim, I Tuncer ^a   Hadgraft, Jonathan ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Diffusion; Human stratum corneum; Molecular modelling; Multivariate regression analysis; Partial charge; Principal component analysis

Indexed keywords

ARTICLE; HYDROGEN BOND; MOLECULAR MODEL; MOLECULAR WEIGHT; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REGRESSION ANALYSIS; SKIN PENETRATION; SKIN PERMEABILITY; STRATUM CORNEUM; SURFACE CHARGE;

DATA INTERPRETATION, STATISTICAL; DIFFUSION; HYDROGEN BONDING; MOLECULAR WEIGHT; REGRESSION ANALYSIS; SKIN; SKIN ABSORPTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033995212     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(00)00326-4     Document Type: Article

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