Analysis of in vitro skin permeation of 22-oxacalcitriol having a complicated metabolic pathway

Pharmaceutical Research

Volumn 23, Issue 4, 2006, Pages 680-688

  Yamaguchi, Koji ^a   Mitsui, Tetsuya ^a   Yamamoto, Toshinori ^a,c   Shiokawa, Rie ^a   Nomiyama, Yuko ^a   Ohishi, Norihisa ^a   Aso, Yoshinori ^a   Sugibayashi, Kenji ^b  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^b JOSAI UNIVERSITY   (Japan)

^c PFIZER INC   (United States)

Author keywords

22 oxacalcitriol; Diffusion model; Rat skin; Skin metabolism; Skin permeation

Indexed keywords

22 OXACALCITRIOL; DRUG METABOLITE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DERMIS; DIFFUSION; DRUG METABOLISM; EPIDERMIS; IN VITRO STUDY; METABOLIC RATE; METABOLISM; NONHUMAN; OINTMENT; PRIORITY JOURNAL; RAT; SKIN METABOLISM; SKIN PERMEABILITY; STRATUM CORNEUM;

ALGORITHMS; ANIMALS; BIOTRANSFORMATION; CALCITRIOL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DERMATOLOGIC AGENTS; DERMIS; DIFFUSION; DIFFUSION CHAMBERS, CULTURE; EPIDERMIS; MALE; RATS; SKIN ABSORPTION;

EID: 33646411475     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-006-9781-z     Document Type: Article

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