Phosphorylation of amyloid precursor protein (APP) at Tyr687 regulates APP processing by α- and γ-secretase

Biochemical and Biophysical Research Communications

Volumn 377, Issue 2, 2008, Pages 544-549

  Takahashi, Keita ^a   Niidome, Tetsuhiro ^a   Akaike, Akinori ^a   Kihara, Takeshi ^a   Sugimoto, Hachiro ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Alzheimer's disease; Amyloid precursor protein; APP processing; Phosphorylation; Tyrosine 687

Indexed keywords

ALPHA SECRETASE; AMINO ACID; AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; SERINE; THREONINE; TYROSINE;

ALZHEIMER DISEASE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; CELL LINE; HUMANS; MUTATION; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; TYROSINE;

EID: 55649121592     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.10.013     Document Type: Article

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