-
1
-
-
0035955712
-
Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid
-
Ando, K., Iijima, K. I., Elliot, J. I., Kirino, Y., & Suzuki, T. (2001). Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid. Journal of Biological Chemistry, 276, 40353-40361.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 40353-40361
-
-
Ando, K.1
Iijima, K.I.2
Elliot, J.I.3
Kirino, Y.4
Suzuki, T.5
-
2
-
-
0032498799
-
AP-2/Eps15 interaction is required for receptor-mediated endocytosis
-
Benmerah, A., Lamaze, C., Begue, B., Schmid, S. L., Dautry-Varsat, A., & Cerf-Bensussan, N. (1998). AP-2/Eps15 interaction is required for receptor-mediated endocytosis. Journal of Cell Biology, 140, 1055-1062.
-
(1998)
Journal of Cell Biology
, vol.140
, pp. 1055-1062
-
-
Benmerah, A.1
Lamaze, C.2
Begue, B.3
Schmid, S.L.4
Dautry-Varsat, A.5
Cerf-Bensussan, N.6
-
3
-
-
0034617199
-
Expression analysis of BACE2 in brain and peripheral tissues
-
Bennett, B. D., Babu-Khan, S., Loeloff, R., Louis, J. C., Curran, E., Citron, M., et al. (2000). Expression analysis of BACE2 in brain and peripheral tissues. Journal of Biological Chemistry, 275, 20647-20651.
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 20647-20651
-
-
Bennett, B.D.1
Babu-Khan, S.2
Loeloff, R.3
Louis, J.C.4
Curran, E.5
Citron, M.6
-
4
-
-
0345654356
-
Molecular analysis of the X11-mLin-2/CASK complex in brain
-
Borg, J. P., Lopez-Figueroa, M. O., de Taddeo-Borg, M., Kroon, D. E., Turner, R. S., Watson, S. J., et al. (1999). Molecular analysis of the X11-mLin-2/CASK complex in brain. Journal of Neuroscience, 19, 1307-1316.
-
(1999)
Journal of Neuroscience
, vol.19
, pp. 1307-1316
-
-
Borg, J.P.1
Lopez-Figueroa, M.O.2
de Taddeo-Borg, M.3
Kroon, D.E.4
Turner, R.S.5
Watson, S.J.6
-
5
-
-
10144251747
-
cDNA cloning and chromosome mapping of the human Fe65 gene: Interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein
-
Bressler, S. L., Gray, M. D., Sopher, B. L., Hu, Q., Hearn, M. G., Pham, D. G., et al. (1996). cDNA cloning and chromosome mapping of the human Fe65 gene: Interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein. Human Molecular Genetics, 5, 1589-1598.
-
(1996)
Human Molecular Genetics
, vol.5
, pp. 1589-1598
-
-
Bressler, S.L.1
Gray, M.D.2
Sopher, B.L.3
Hu, Q.4
Hearn, M.G.5
Pham, D.G.6
-
6
-
-
0025250145
-
NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low-density lipoprotein receptor
-
Chen, W. J., Goldstein, J. L., & Brown, M. S. (1990). NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low-density lipoprotein receptor. Journal of Biological Chemistry, 265, 3116-3123.
-
(1990)
Journal of Biological Chemistry
, vol.265
, pp. 3116-3123
-
-
Chen, W.J.1
Goldstein, J.L.2
Brown, M.S.3
-
7
-
-
14844286856
-
Gamma-secretase complex assembly within the early secretory pathway
-
Capell, A., Beher, D., Prokop, S., Steiner, H., Kaether, C., Shearman, M. S., et al. (2005). Gamma-secretase complex assembly within the early secretory pathway. Journal of Biological Chemistry, 280, 6471-6478.
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 6471-6478
-
-
Capell, A.1
Beher, D.2
Prokop, S.3
Steiner, H.4
Kaether, C.5
Shearman, M.S.6
-
8
-
-
0141705361
-
-
da Cruz e Silva, E. F., & da Cruz e Silva, O. A. (2003). Protein phosphorylation and APP metabolism. Neurochemical Research, 28, 1553-1561.
-
da Cruz e Silva, E. F., & da Cruz e Silva, O. A. (2003). Protein phosphorylation and APP metabolism. Neurochemical Research, 28, 1553-1561.
-
-
-
-
9
-
-
4344704079
-
-
da Cruz e Silva, O. A., Fardilha, M., Henriques, A. G., Rebelo, S., Vieira, S., & da Cruz e Silva, E. F. (2004a). Signal transduction therapeutics: Relevance for Alzheimer's disease. Journal of Molecular Neuroscience, 23, 123-142.
-
da Cruz e Silva, O. A., Fardilha, M., Henriques, A. G., Rebelo, S., Vieira, S., & da Cruz e Silva, E. F. (2004a). Signal transduction therapeutics: Relevance for Alzheimer's disease. Journal of Molecular Neuroscience, 23, 123-142.
-
-
-
-
10
-
-
9244229070
-
-
da Cruz e Silva, O. A., Vieira, S. I., Rebelo, S., & da Cruz e Silva, E. F. (2004b). A model system to study intracellular trafficking and processing of the Alzheimer's Amyloid Precursor Protein. Neurodegenerative Diseases, 1, 196-204.
-
da Cruz e Silva, O. A., Vieira, S. I., Rebelo, S., & da Cruz e Silva, E. F. (2004b). A model system to study intracellular trafficking and processing of the Alzheimer's Amyloid Precursor Protein. Neurodegenerative Diseases, 1, 196-204.
-
-
-
-
11
-
-
0037022644
-
Activity-dependent isolation of the presenilin-gamma-secretase complex reveals nicastrin and a gamma substrate
-
Esler, W. P., Kimberly, W. T., Ostaszewski, B. L., Ye, W., Diehl, T. S., Selkoe, D. J., et al. (2002). Activity-dependent isolation of the presenilin-gamma-secretase complex reveals nicastrin and a gamma substrate. Proceedings of the National Academy of Sciences of the United States of America, 99, 2720-2725.
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, pp. 2720-2725
-
-
Esler, W.P.1
Kimberly, W.T.2
Ostaszewski, B.L.3
Ye, W.4
Diehl, T.S.5
Selkoe, D.J.6
-
12
-
-
9244246339
-
Lithium decreases secretion of Aβ1-42 and C-truncated species Aβ1-37/38/39/40 in chicken telencephalic cultures but specifically increases intracellular Aβ1-38
-
Esselmann, H., Maler, J. M., Kunz, N., Otto, M., Paul, S., Lewczuk, P., et al. (2004). Lithium decreases secretion of Aβ1-42 and C-truncated species Aβ1-37/38/39/40 in chicken telencephalic cultures but specifically increases intracellular Aβ1-38. Neurodegenerative Diseases, 1, 236-241.
-
(2004)
Neurodegenerative Diseases
, vol.1
, pp. 236-241
-
-
Esselmann, H.1
Maler, J.M.2
Kunz, N.3
Otto, M.4
Paul, S.5
Lewczuk, P.6
-
13
-
-
0028030517
-
Regulated cleavage of the Alzheimer amyloid precursor protein: Molecular and cellular basis
-
Gandy, S., & Greengard, P. (1994). Regulated cleavage of the Alzheimer amyloid precursor protein: Molecular and cellular basis. Biochimie, 76, 300-303.
-
(1994)
Biochimie
, vol.76
, pp. 300-303
-
-
Gandy, S.1
Greengard, P.2
-
14
-
-
0033198295
-
Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1
-
Homayouni, R., Rice, D. S., Sheldon, M., & Curran, T. (1999). Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1. Journal of Neuroscience, 19, 7507-7515.
-
(1999)
Journal of Neuroscience
, vol.19
, pp. 7507-7515
-
-
Homayouni, R.1
Rice, D.S.2
Sheldon, M.3
Curran, T.4
-
15
-
-
0037047434
-
The gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein induces apoptosis via Tip60 in H4 cells
-
Kinoshita, A., Whelan, C. M., Berezovska, O., & Hyman, B. T. (2002). The gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein induces apoptosis via Tip60 in H4 cells. Journal of Biological Chemistry, 277, 28530-28536.
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 28530-28536
-
-
Kinoshita, A.1
Whelan, C.M.2
Berezovska, O.3
Hyman, B.T.4
-
16
-
-
0028276801
-
Evidence that production and release of amyloid beta-protein involves the endocytic pathway
-
Koo, E. H., & Squazzo, S. L. (1994). Evidence that production and release of amyloid beta-protein involves the endocytic pathway. Journal of Biological Chemistry, 269, 17386-17389.
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 17386-17389
-
-
Koo, E.H.1
Squazzo, S.L.2
-
17
-
-
0030740213
-
Solution conformations of a peptide containing the cytoplasmic domain sequence of the beta amyloid precursor protein
-
Kroenke, C. D., Ziemnicka-Kotula, D., Xu, J., Kotula, L., & Palmer, A. G. (1997). Solution conformations of a peptide containing the cytoplasmic domain sequence of the beta amyloid precursor protein. Biochemistry, 36, 8145-8152.
-
(1997)
Biochemistry
, vol.36
, pp. 8145-8152
-
-
Kroenke, C.D.1
Ziemnicka-Kotula, D.2
Xu, J.3
Kotula, L.4
Palmer, A.G.5
-
18
-
-
0028966092
-
Characterization of sorting signals in the beta-amyloid precursor protein cytoplasmic domain
-
Lai, A., Sisodia, S. S., & Trowbridge, I. S. (1995). Characterization of sorting signals in the beta-amyloid precursor protein cytoplasmic domain. Journal of Biological Chemistry, 270, 3565-3573.
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 3565-3573
-
-
Lai, A.1
Sisodia, S.S.2
Trowbridge, I.S.3
-
19
-
-
0037160063
-
Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch
-
Lee, S. F., Shah, S., Li, H., Yu, C., Han, W., & Yu, G. (2000). Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch. Journal of Biological Chemistry, 277, 45013-45019.
-
(2000)
Journal of Biological Chemistry
, vol.277
, pp. 45013-45019
-
-
Lee, S.F.1
Shah, S.2
Li, H.3
Yu, C.4
Han, W.5
Yu, G.6
-
20
-
-
0142123260
-
APP processing is regulated by cytoplasmic phosphorylation
-
Lee, M. S., Kao, S. C., Lemere, C. A., Xia, W., Tseng, H. C., Zhou, Y., et al. (2003). APP processing is regulated by cytoplasmic phosphorylation. Journal of Cell Biology, 163, 83-95.
-
(2003)
Journal of Cell Biology
, vol.163
, pp. 83-95
-
-
Lee, M.S.1
Kao, S.C.2
Lemere, C.A.3
Xia, W.4
Tseng, H.C.5
Zhou, Y.6
-
21
-
-
0343819757
-
Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state
-
Li, Y. M., Lai, M. T., Xu, M., Huang, Q., DiMuzio-Mower, J., Sardana, M. K., et al. (2000a). Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state. Proceedings of the National Academy of Sciences of the United States of America, 97, 6138-6143.
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, pp. 6138-6143
-
-
Li, Y.M.1
Lai, M.T.2
Xu, M.3
Huang, Q.4
DiMuzio-Mower, J.5
Sardana, M.K.6
-
22
-
-
0034621824
-
Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1
-
Li, Y. M., Xu, M., Lai, M. T., Huang, Q., Castro, J. L., DiMuzio-Mower, J., et al. (2000b). Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1. Nature, 405, 689-694.
-
(2000)
Nature
, vol.405
, pp. 689-694
-
-
Li, Y.M.1
Xu, M.2
Lai, M.T.3
Huang, Q.4
Castro, J.L.5
DiMuzio-Mower, J.6
-
23
-
-
0030592773
-
The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system
-
McLoughlin, D. M., & Miller, C. C. (1999). The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system. FEBS Letters, 397, 197-200.
-
(1999)
FEBS Letters
, vol.397
, pp. 197-200
-
-
McLoughlin, D.M.1
Miller, C.C.2
-
24
-
-
33646732989
-
Role of APP phosphorylation in FE65-dependent gene transactivation mediated by AICD
-
Nakaya, T., & Suzuki, T. (2006). Role of APP phosphorylation in FE65-dependent gene transactivation mediated by AICD. Genes Cells, 11, 633-645.
-
(2006)
Genes Cells
, vol.11
, pp. 633-645
-
-
Nakaya, T.1
Suzuki, T.2
-
25
-
-
0035078189
-
The neuronal endosomal-lysosomal system in Alzheimer's disease
-
Nixon, R. A., Mathews, P. M., & Cataldo, A. M. (2001). The neuronal endosomal-lysosomal system in Alzheimer's disease. Journal of Alzheimer's Disease, 3, 97-107.
-
(2001)
Journal of Alzheimer's Disease
, vol.3
, pp. 97-107
-
-
Nixon, R.A.1
Mathews, P.M.2
Cataldo, A.M.3
-
26
-
-
0030954298
-
The cytoplasmic domain of Alzheimer's amyloid precursor protein is phosphorylated at Thr654, Ser655, and Thr668 in adult rat brain and cultured cells
-
Oishi, M., Nairn, A. C., Czernik, A. J., Lim, G. S., Isohara, T., Gandy, et al. (1997). The cytoplasmic domain of Alzheimer's amyloid precursor protein is phosphorylated at Thr654, Ser655, and Thr668 in adult rat brain and cultured cells. Molecular Medicine, 3, 111-123.
-
(1997)
Molecular Medicine
, vol.3
, pp. 111-123
-
-
Oishi, M.1
Nairn, A.C.2
Czernik, A.J.3
Lim, G.S.4
Isohara, T.5
Gandy6
-
27
-
-
0033516554
-
Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42
-
Perez, R. G., Soriano, S., Hayes, J. D., Ostaszewski, B., Xia, W., Selkoe, D. J., et al. (1999). Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42. Journal of Biological Chemistry, 274, 18851-18856.
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 18851-18856
-
-
Perez, R.G.1
Soriano, S.2
Hayes, J.D.3
Ostaszewski, B.4
Xia, W.5
Selkoe, D.J.6
-
28
-
-
0034646447
-
Transient structure of the amyloid precursor protein cytoplasmic tail indicates preordering of structure for binding to cytosolic factors
-
Ramelot, T. A., Gentile, L. N., & Nicholson, L. K. (2000). Transient structure of the amyloid precursor protein cytoplasmic tail indicates preordering of structure for binding to cytosolic factors. Biochemistry, 39, 2714-2725.
-
(2000)
Biochemistry
, vol.39
, pp. 2714-2725
-
-
Ramelot, T.A.1
Gentile, L.N.2
Nicholson, L.K.3
-
29
-
-
2342473913
-
Effect of cell density on intracellular levels of the Alzheimer's amyloid precursor protein
-
Rebelo, S., Henriques, A. G., da Cruz E Silva, E. F., & da Cruz E Silva, A. O. B. (2004). Effect of cell density on intracellular levels of the Alzheimer's amyloid precursor protein. Journal of Neuroscience Research, 76, 406-414.
-
(2004)
Journal of Neuroscience Research
, vol.76
, pp. 406-414
-
-
Rebelo, S.1
Henriques, A.G.2
da Cruz, E.3
Silva, E.F.4
da Cruz, E.5
Silva, A.O.B.6
-
30
-
-
0035954426
-
The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement
-
Sabo, S. L., Ikin, A. F., Buxbaum, J. D., & Greengard, P. (2001). The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement. Journal of Cell Biology, 153, 1403-1414.
-
(2001)
Journal of Cell Biology
, vol.153
, pp. 1403-1414
-
-
Sabo, S.L.1
Ikin, A.F.2
Buxbaum, J.D.3
Greengard, P.4
-
31
-
-
0037131218
-
PEN-2 is an integral component of the gamma-secretase complex required for coordinated expression of presenilin and nicastrin
-
Steiner, H., Winkler, E., Edbauer, D., Prokop, S., Basset, G., Yamasaki, A., et al. (2002). PEN-2 is an integral component of the gamma-secretase complex required for coordinated expression of presenilin and nicastrin. Journal of Biological Chemistry, 277, 39062-39065J.
-
(2002)
Journal of Biological Chemistry
, vol.277
-
-
Steiner, H.1
Winkler, E.2
Edbauer, D.3
Prokop, S.4
Basset, G.5
Yamasaki, A.6
-
32
-
-
0036064769
-
Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of beta-APP
-
Tarr, P. E., Contursi, C., Roncarati, R., Noviello, C., Ghersi, E., Scheinfeld, M. H., et al. (2002). Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of beta-APP. Biochemical and Biophysical Research Communications, 295, 324-329.
-
(2002)
Biochemical and Biophysical Research Communications
, vol.295
, pp. 324-329
-
-
Tarr, P.E.1
Contursi, C.2
Roncarati, R.3
Noviello, C.4
Ghersi, E.5
Scheinfeld, M.H.6
-
33
-
-
0033595706
-
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar, R., Bennett, B. D., Babu-Khan, S., Kahn, S., Mendiaz, E. A., Denis, P., et al. (1999). Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science, 286, 735-741.
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
Denis, P.6
-
34
-
-
34548824757
-
-
Verdile, G., Gandy, S. E., Martins, R. N. (2006). The Role of Presenilin and its Interacting Proteins in the Biogenesis of Alzheimer's Beta Amyloid. Neurochemical Research 2006 Aug 31, in press.
-
Verdile, G., Gandy, S. E., Martins, R. N. (2006). The Role of Presenilin and its Interacting Proteins in the Biogenesis of Alzheimer's Beta Amyloid. Neurochemical Research 2006 Aug 31, in press.
-
-
-
-
35
-
-
20444377260
-
GGA proteins regulate retrograde transport of BACE1 from endosomes to the trans-Golgi network
-
Wahle, T., Prager, K., Raffler, N., Haass, C., Famulok, M., & Walter, J. (2005). GGA proteins regulate retrograde transport of BACE1 from endosomes to the trans-Golgi network. Molecular and Cellular Biochemistry, 29, 453-461.
-
(2005)
Molecular and Cellular Biochemistry
, vol.29
, pp. 453-461
-
-
Wahle, T.1
Prager, K.2
Raffler, N.3
Haass, C.4
Famulok, M.5
Walter, J.6
-
36
-
-
0035900774
-
Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells
-
Wiltfang, J., Esselmann, H., Cupers, P., Neumann, M., Kretzschmar, H., Beyermann, M., et al. (2001). Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells. Journal of Biological Chemistry, 276, 42645-42657.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 42645-42657
-
-
Wiltfang, J.1
Esselmann, H.2
Cupers, P.3
Neumann, M.4
Kretzschmar, H.5
Beyermann, M.6
-
37
-
-
18444393054
-
Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation
-
Wiltfang, J., Esselmann, H., Bibl, M., Smirnov, A., Otto, M., Paul, S., et al. (2002). Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation. Journal of Neurochemistry, 81, 481-496.
-
(2002)
Journal of Neurochemistry
, vol.81
, pp. 481-496
-
-
Wiltfang, J.1
Esselmann, H.2
Bibl, M.3
Smirnov, A.4
Otto, M.5
Paul, S.6
-
38
-
-
0035823610
-
BACE2 functions as an alternative alpha-secretase in cells
-
Yan, R., Munzner, J. B., Shuck, M. E., & Bienkowski, M. J. (2001). BACE2 functions as an alternative alpha-secretase in cells. Journal of Biological Chemistry, 276, 34019-34027.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 34019-34027
-
-
Yan, R.1
Munzner, J.B.2
Shuck, M.E.3
Bienkowski, M.J.4
-
39
-
-
0035827587
-
The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene
-
Zambrano, N., Bruni, P., Minopoli, G., Mosca, R., Molino, D., Russo, C., et al. (2001). The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene. Journal of Biological Chemistry, 276, 19787-19792.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 19787-19792
-
-
Zambrano, N.1
Bruni, P.2
Minopoli, G.3
Mosca, R.4
Molino, D.5
Russo, C.6
|