Simultaneous determination of saccharin and aspartame in commercial noncaloric sweeteners using the PLS-2 multivariate calibration method and validation by capillary electrophoresis

Journal of Agricultural and Food Chemistry

Volumn 56, Issue 20, 2008, Pages 9345-9349

  Cantarelli, Miguel A ^a   Pellerano, Roberto G ^b   Marchevsky, Eduardo J ^b   Camiña, José M ^a  

^a UNIVERSIDAD NACIONAL DE LA PAMPA   (Argentina)

^b UNIVERSIDAD NACIONAL DE SAN LUIS   (Argentina)

Author keywords

Aspartame; Capillary electrophoresis; Multivariate calibration; PLS 2 method; Sodium saccharin; Sweeteners

Indexed keywords

ASPARTAME; SACCHARIN; SWEETENING AGENT;

ARTICLE; CALIBRATION; CAPILLARY ELECTROPHORESIS; EVALUATION; METHODOLOGY; MULTIVARIATE ANALYSIS; REGRESSION ANALYSIS; SPECTROPHOTOMETRY; STANDARD; STATISTICAL MODEL;

ASPARTAME; CALIBRATION; ELECTROPHORESIS, CAPILLARY; LEAST-SQUARES ANALYSIS; MODELS, STATISTICAL; MULTIVARIATE ANALYSIS; SACCHARIN; SPECTROPHOTOMETRY; SWEETENING AGENTS;

EID: 55549129641     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf801972q     Document Type: Article

References (36)

1. International Sweeteners Association, Brussels, Belgium, 2004; http://www.isabru.org/.
2. Mitchell, M.; Pearson, R. L. In Saccharin in Alternative Sweetener; O'Brien, L., Gelardi, R. C., Eds.; Marcel Dekker: New York, 1991; pp 127-156.
3. Homler, B. E.; Deis, R. C.; Shazer, W. Aspartame in Alternative Sweetener; O'Brien, L., Gelardi, R. C., Eds.; Marcel Dekker: New York, 1991; pp 39-70.
4. Wasik, A.; McCourt, J.; Buchgraber, M. Simultaneous determination of nine intense sweeteners in foodstuffs by high performance liquid chromatography. J. Chromatogr. A 2007, 1157, 187-96.
5. Tsang, W. S.; Clarke, M. A.; Parrish, F. W. Determination of aspartame and its breakdown products in soft drinks by reverse phase chromatography with UV detection. J. Agric. Food Chem. 1985, 33, 734-738.
6. Kobayashi, C.; Nakazato, M.; Ushiyama, H.; Kawai, Y.; Tateishi, Y.; Yasuda, K. Simultaneous determination of five sweeteners in foods by HPLC. Shokuhin Eiseigaku Zasshi 1999, 40, 166-171.
7. Dossi, N.; Toniolo, R.; Susmel, S.; Pizzariello, A.; Bontempelli, G. Simultaneous RP-LC determination of additives in soft drinks. Chromatographia 2006, 63, 557-562.
8. Wu, P. W.; Cheng, C. C.; Chou, S. S. Determination of acesulfame-K, saccharin, aspartame, dulcin and cyclamate in beverages. J. Chin. Agric. Chem. Soc. 1995, 33, 37-50.
9. Zhu, Y.; Guo, Y.; Ye, M.; James, F. S. Separation and simultaneous determination of four artificial sweeteners in food and beverages by ion chromatography. J. Chromatogr. A 2005, 1085, 143-146.
10. Chen, Q. C.; Wang, J. Simultaneous determination of artificial sweeteners, preservatives, caffeine, theobromine and theophylline in food and pharmaceutical preparations by ion chromatography. J. Chromatogr. A 2001, 937, 57-64.
11. Qu, F.; Qi, Z. H.; Liu, K. N.; Mou, S. F. Determination of aspartame by ion chromatography with electrochemical integrated amperometric detection. J. Chromatogr. A 1999, 850, 277-281.
12. Herrmannova, M.; Krivankova, L.; Bartos, M. Direct simultaneous determination of eight sweeteners in foods by capillary isotachophoresis. J. Sep. Sci. 2006, 29, 1132-1137.
13. Pesek, J. J.; Matyska, M. T. Determination of aspartame by high-performance capillary electrophoresis. J. Chromatogr. A 1997, 781, 423-428.
14. Berzas-Nevado, J. J.; Guiberteau-Cabanillas, C.; Contento-Salcedo, A. M. Method development and validation for the simultaneous determination of dyes in foodstuffs by capillary zone electrophoresis. Anal. Chim. Acta 1999, 378, 63-71.
15. Boyce, M. C. Simultaneous determination of antioxidants, preservatives and sweeteners permitted as additives in foods by mixed micellar electrokinetic chromatography. J. Chromatogr. A 1999, 847, 369-375.
16. McCourt, J.; Stroka, J.; Anklam, E. Experimental design-based development and single laboratory validation of a capillary zone electrophoresis method for the determination of the artificial sweetener sucralose in food matrices. Anal. Bioanal. Chem. 2005, 382, 1269-1278.
17. Huang, H. Y.; Chiu, C. W.; Sue, S. L.; Cheng, C. F. Analysis of food colorants by capillary electrophoresis with large-volume sample stacking. J. Chromatogr. A 2003, 995, 29-36.
18. Frazier, R. A.; Inns, E. L.; Dossi, N.; Ames, J. M.; Nursten, H. E. Development of a capillary electrophoresis method for the simultaneous analysis of artificial sweeteners, preservatives and colours in soft drinks. J. Chromatogr. A 2000, 876, 213-220.
19. Armenta, S.; Garrigues, S.; De La Guardia, M. FTIR determination of aspartame and acesulfame-K in table top sweeteners. J. Agric. Food Chem. 2004, 52, 7798-7803.
20. Armenta, S.; Garrigues, S.; De La Guardia, M. Sweeteners determination in table top formulations using FT-Raman spectrometry and chemometric analysis. Anal. Chim. Acta 2004, 521, 149-155.
21. Khurana, H. K.; Cho, I. K.; Shim, J. Y.; Li, Q. X.; Jun, S. Application of multibounce attenuated total reflectance fourier transform infrared spectroscopy and chemometrics for determination of aspartame in soft drinks. J. Agric. Food Chem. 2008, 56, 778-783.
22. Nikolelis, D. P.; Pantoulias, S. A minisensor for the rapid screening of acesulfame-K, cyclamate and saccharin based on surface-stabilized bilayer lipid membranes. Electroanalysis 2000, 12, 786-790.
23. Fatibello-Filho, O.; Marcolino-Junior, L. H.; Pereira, A. V. Solid-phase reactor with copper(II) phosphate for flow-injection spectrophotometric determination of aspartame in tabletop sweeteners. Anal. Chim. Acta 1999, 384, 167-174.
24. Odaci, D.; Timur, S.; Telefoncu, A. Carboxyl esterase-alcohol oxidase based biosensor for the aspartame determination. Food Chem. 2004, 84, 493-496.
25. Fatibello-Filho, O.; Aniceto, C. Potentiometric determination of Saccharin in dietary products using a coated-carbon rod ion selective electrode. Anal. Lett. 1997, 30, 1653-1666.
26. Filho, J. C.; Oppermann Santini, A.; Nasser, A. L. M.; Pezza, H. R.; de Oliveira, J. E.; Melios, C. B.; Pezza, L. Potentiometric determination of saccharin in commercial artificial sweeteners using a silver electrode. Food Chem. 2003, 83, 297-301.
27. Pena, R. M.; Lima, J. L. F. C.; Saraiva, M.; Lucia, M. F. S. Sequential injection analysis-based flow system for the enzymatic determination of aspartame. Anal. Chim. Acta 2004, 514, 37-43.
28. Vallvey, C. L. F.; Valencia, M. C. E.; Nicolas, A.; García- Jiménez, J. F. Resolution of an intense sweetener mixture by use of a flow injection sensor with on-line solid-phase extraction. Application to saccharin and aspartame in sweets and drinks. Anal. Bioanal. Chem. 2006, 385, 385-391.
29. Massart, D. L.; Vandeginste, B. G. M.; Buydens, L. M. C.; De Jong, S.; Lewi, P. J.; Smeyers-Verbeke, J. Handbook of Chemometrics and Qualimetrics; Elsevier: Amsterdam, 1997; Vol. A, pp 366-368.
30. Beebe, K. R.; Pell, R. J.; Seasholtz, M. B. Chemometrics: A Practical Guide; John Wiley and Sons: New York, 1998; pp 278-283, 292.
31. Kellner, R.; Mermet, J. M.; Otto, M.; Valcárcel, M.; Widmer, H. M. Analytical Chemistry, 2nd ed.; Wiley-VCH: Weinheim, 2004; pp 127-130.
32. Martens, H.; Naes, T. Multivariate Calibration; John Wiley and Sons: New York, 1996; pp 116, 290-291.
33. Meites, L. Handbook of Analytical Chemistry; Mc Graw Hill: New York, 1963; pp 11-12.
34. Lozano, V. A.; Camiña, J. M.; Boeris, M. S.; Maerchesvky, E. J. Simultaneous determination of sorbic and benzoic acids in commercial juices using the PLS-2 multivariate calibration method and validation by high performance liquid chromatography. Talanta 2007, 73, 282-286.
35. Sikorska, E.; Gliszczynska-Swiglo, A.; Insinska-Rak, M.; Khmelinskii, I.; De Keukeleire, D.; Sikorski, M. Simultaneous analysis of riboflavin and aromatic amino acids in beer using fluorescence and multivariate calibration methods. Anal. Chim. Acta 2008, 613, 207-217.
36. Miller, J. N.; Miller, J. C. Estadística y Quimiometría para Química Analítica, 4th ed.; Pearson Educación S.A.: Madrid, 2002; pp 45-55.