Genome-scale reconstruction and analysis of the Pseudomonas putida KT2440 metabolic network facilitates applications in biotechnology

PLoS Computational Biology

Volumn 4, Issue 10, 2008, Pages

  Puchałka, Jacek ^a   Oberhardt, Matthew A ^b   Godinho, Miguel ^a   Bielecka, Agata ^a   Regenhardt, Daniela ^a   Timmis, Kenneth N ^a   Papin, Jason A ^b   Martins Dos Santos, Vítor A P ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CELL CULTURE; GENES; METABOLIC ENGINEERING; PHYSIOLOGY;

BIOCATALYSIS; CONSTRAINT-BASED MODELING; CONSTRAINTS-BASED MODELING; FLUX BALANCE ANALYSIS; GENETIC MODIFICATIONS; METABOLIC NETWORK; METABOLIC VERSATILITY; NETWORK RECONSTRUCTION; PSEUDOMONAS PUTIDA; STRESS RESISTANCE;

METABOLISM;

CARBON; ISOENZYME; POLYHYDROXYALKANOIC ACID;

ARTICLE; AUXOTROPHY; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIAL STRAIN; BIOTECHNOLOGICAL PRODUCTION; CELL SURVIVAL; CONTROLLED STUDY; DNA MODIFICATION; GENOME ANALYSIS; METABOLIC ENGINEERING; METABOLIC PARAMETERS; NONHUMAN; PHENOTYPIC PLASTICITY; PSEUDOMONAS PUTIDA; BACTERIAL GENOME; BIOCATALYSIS; BIOLOGICAL MODEL; BIOMASS; BIOSYNTHESIS; BIOTECHNOLOGY; GENETIC DATABASE; GENETICS; GENOMICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; METHODOLOGY; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS; SYSTEMS BIOLOGY;

BACTERIA (MICROORGANISMS); PSEUDOMONAS PUTIDA;

BIOCATALYSIS; BIOMASS; BIOTECHNOLOGY; DATABASES, GENETIC; GENOME, BACTERIAL; GENOMICS; METABOLIC NETWORKS AND PATHWAYS; MODELS, BIOLOGICAL; MUTAGENESIS, SITE-DIRECTED; POLYHYDROXYALKANOATES; PSEUDOMONAS PUTIDA; SYSTEMS BIOLOGY;

EID: 55449096123     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000210     Document Type: Article

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