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Volumn 68, Issue 21, 2008, Pages 8928-8937

Bioselection of a gain of function mutation that enhances adenovirus 5 release and improves its antitumoral potency

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; ONCOLYTIC VIRUS;

EID: 55349119141     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-1145     Document Type: Article
Times cited : (53)

References (51)
  • 1
    • 33846650370 scopus 로고    scopus 로고
    • Clinical trial results with oncolytic virotherapy: A century of promise, a decade of progress
    • Liu TC, Galanis E, Kirn D. Clinical trial results with oncolytic virotherapy: a century of promise, a decade of progress. Nat Clin Pract Oncol 2007;4:101-17.
    • (2007) Nat Clin Pract Oncol , vol.4 , pp. 101-117
    • Liu, T.C.1    Galanis, E.2    Kirn, D.3
  • 2
    • 33847319116 scopus 로고    scopus 로고
    • Cancer selective adenoviruses
    • Alemany R. Cancer selective adenoviruses. Mol Aspects Med 2007;28:42-58.
    • (2007) Mol Aspects Med , vol.28 , pp. 42-58
    • Alemany, R.1
  • 3
    • 27944433469 scopus 로고    scopus 로고
    • Oncolytic viral therapies - the clinical experience
    • Aghi M, Martuza RL. Oncolytic viral therapies - the clinical experience. Oncogene 2005;24:7802-16.
    • (2005) Oncogene , vol.24 , pp. 7802-7816
    • Aghi, M.1    Martuza, R.L.2
  • 4
    • 4143092630 scopus 로고    scopus 로고
    • Use of replicating oncolytic adenoviruses in combination therapy for cancer
    • Chu RL, Post DE, Khuri FR, Van Meir EG. Use of replicating oncolytic adenoviruses in combination therapy for cancer. Clin Cancer Res 2004;10:5299-312.
    • (2004) Clin Cancer Res , vol.10 , pp. 5299-5312
    • Chu, R.L.1    Post, D.E.2    Khuri, F.R.3    Van Meir, E.G.4
  • 5
    • 0038518576 scopus 로고    scopus 로고
    • Phase II trial of intravenous CI-1042 in patients with metastatic colorectal cancer
    • Hamid O, Varterasian ML, Wadler S, et al. Phase II trial of intravenous CI-1042 in patients with metastatic colorectal cancer. J Clin Oncol 2003;21:1498-504.
    • (2003) J Clin Oncol , vol.21 , pp. 1498-1504
    • Hamid, O.1    Varterasian, M.L.2    Wadler, S.3
  • 6
    • 33745161873 scopus 로고    scopus 로고
    • A phase I trial of intravenous CG7870, a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic prostate cancer
    • Small EJ, Carducci MA, Burke JM, et al. A phase I trial of intravenous CG7870, a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic prostate cancer. Mol Ther 2006;14:107-17.
    • (2006) Mol Ther , vol.14 , pp. 107-117
    • Small, E.J.1    Carducci, M.A.2    Burke, J.M.3
  • 7
    • 0033756313 scopus 로고    scopus 로고
    • Blood clearance rates of adenovirus type 5 in mice
    • Alemany R, Suzuki K, Curiel DT. Blood clearance rates of adenovirus type 5 in mice. J Gen Virol 2000;81:2605-9.
    • (2000) J Gen Virol , vol.81 , pp. 2605-2609
    • Alemany, R.1    Suzuki, K.2    Curiel, D.T.3
  • 8
    • 0346242736 scopus 로고    scopus 로고
    • The effect of sequestration by nontarget tissues on anti-tumor efficacy of systemically applied, conditionally replicating adenovirus vectors
    • Bernt KM, Ni S, Gaggar A, et al. The effect of sequestration by nontarget tissues on anti-tumor efficacy of systemically applied, conditionally replicating adenovirus vectors. Mol Ther 2003;8:746-55.
    • (2003) Mol Ther , vol.8 , pp. 746-755
    • Bernt, K.M.1    Ni, S.2    Gaggar, A.3
  • 9
    • 11144248909 scopus 로고    scopus 로고
    • The innate immune response to adenovirus vectors
    • Muruve DA. The innate immune response to adenovirus vectors. Hum Gene Ther 2004;15:1157-66.
    • (2004) Hum Gene Ther , vol.15 , pp. 1157-1166
    • Muruve, D.A.1
  • 10
    • 0030563195 scopus 로고    scopus 로고
    • Adenoviruses as gene-delivery vehicles
    • Wilson JM. Adenoviruses as gene-delivery vehicles. N Engl J Med 1996;334:1185-7.
    • (1996) N Engl J Med , vol.334 , pp. 1185-1187
    • Wilson, J.M.1
  • 11
    • 34548137729 scopus 로고    scopus 로고
    • Systemic toxicity-efficacy profile of ICOVIR-5, a potent and selective oncolytic adenovirus based on the pRB pathway
    • Cascallo M, Alonso MM, Rojas JJ, et al. Systemic toxicity-efficacy profile of ICOVIR-5, a potent and selective oncolytic adenovirus based on the pRB pathway. Mol Ther 2007;15:1607-15.
    • (2007) Mol Ther , vol.15 , pp. 1607-1615
    • Cascallo, M.1    Alonso, M.M.2    Rojas, J.J.3
  • 12
    • 0037457032 scopus 로고    scopus 로고
    • Intratumoral spread of wild-type adenovirus is limited after local injection of human xenograft tumors: Virus persists and spreads systemically at late time points
    • Sauthoff H, Hu J, Maca C, et al. Intratumoral spread of wild-type adenovirus is limited after local injection of human xenograft tumors: virus persists and spreads systemically at late time points. Hum Gene Ther 2003;14:425-33.
    • (2003) Hum Gene Ther , vol.14 , pp. 425-433
    • Sauthoff, H.1    Hu, J.2    Maca, C.3
  • 13
    • 0037444281 scopus 로고    scopus 로고
    • Validation and analysis of a mathematical model of a replication-competent oncolytic virus for cancer treatment: Implications for virus design and delivery
    • Wein LM, Wu JT, Kirn DH. Validation and analysis of a mathematical model of a replication-competent oncolytic virus for cancer treatment: implications for virus design and delivery. Cancer Res 2003;63:1317-24.
    • (2003) Cancer Res , vol.63 , pp. 1317-1324
    • Wein, L.M.1    Wu, J.T.2    Kirn, D.H.3
  • 14
    • 0034086730 scopus 로고    scopus 로고
    • Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein
    • Doronin K, Toth K, Kuppuswamy M, et al. Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein. J Virol 2000;74:6147-55.
    • (2000) J Virol , vol.74 , pp. 6147-6155
    • Doronin, K.1    Toth, K.2    Kuppuswamy, M.3
  • 16
    • 0033556003 scopus 로고    scopus 로고
    • Therapy of colon cancer with oncolytic adenovirus is enhanced by the addition of herpes simplex virus-thymidine kinase
    • Wildner O, Blaese RM, Morris JC. Therapy of colon cancer with oncolytic adenovirus is enhanced by the addition of herpes simplex virus-thymidine kinase. Cancer Res 1999;59:410-3.
    • (1999) Cancer Res , vol.59 , pp. 410-413
    • Wildner, O.1    Blaese, R.M.2    Morris, J.C.3
  • 17
    • 0037812877 scopus 로고    scopus 로고
    • In vitro and in vivo activities of an oncolytic adenoviral vector designed to express GM-CSF
    • Bristol JA, Zhu M, Ji H, et al. In vitro and in vivo activities of an oncolytic adenoviral vector designed to express GM-CSF. Mol Ther 2003;7:755-64.
    • (2003) Mol Ther , vol.7 , pp. 755-764
    • Bristol, J.A.1    Zhu, M.2    Ji, H.3
  • 18
    • 0037323323 scopus 로고    scopus 로고
    • Developing novel oncolytic adenoviruses through bioselection
    • Yan W, Kitzes G, Dormishian F, et al. Developing novel oncolytic adenoviruses through bioselection. J Virol 2003;77:2640-50.
    • (2003) J Virol , vol.77 , pp. 2640-2650
    • Yan, W.1    Kitzes, G.2    Dormishian, F.3
  • 19
    • 32444433144 scopus 로고    scopus 로고
    • Genetic identification of adenovirus type 5 genes that influence viral spread
    • Subramanian T, Vijayalingam S, Chinnadurai G. Genetic identification of adenovirus type 5 genes that influence viral spread. J Virol 2006;80:2000-12.
    • (2006) J Virol , vol.80 , pp. 2000-2012
    • Subramanian, T.1    Vijayalingam, S.2    Chinnadurai, G.3
  • 20
    • 7844240481 scopus 로고    scopus 로고
    • Disruption of the antiproliferative TGF-β signaling pathways in human pancreatic cancer cells
    • Villanueva A, Garcia C, Paules AB, et al. Disruption of the antiproliferative TGF-β signaling pathways in human pancreatic cancer cells. Oncogene 1998;17:1969-78.
    • (1998) Oncogene , vol.17 , pp. 1969-1978
    • Villanueva, A.1    Garcia, C.2    Paules, A.B.3
  • 21
    • 0027076049 scopus 로고
    • Expression of the human MUC1 mucin cDNA in a hamster pancreatic tumor cell line HP-1
    • Batra SK, Metzgar RS, Worlock AJ, Hollingsworth MA. Expression of the human MUC1 mucin cDNA in a hamster pancreatic tumor cell line HP-1. Int J Pancreatol 1992;12:271-83.
    • (1992) Int J Pancreatol , vol.12 , pp. 271-283
    • Batra, S.K.1    Metzgar, R.S.2    Worlock, A.J.3    Hollingsworth, M.A.4
  • 22
    • 0034830243 scopus 로고    scopus 로고
    • CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors
    • Alemany R, Curiel DT. CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors. Gene Ther 2001;8:1347-53.
    • (2001) Gene Ther , vol.8 , pp. 1347-1353
    • Alemany, R.1    Curiel, D.T.2
  • 24
    • 33750607468 scopus 로고    scopus 로고
    • Deletion of VAI and VAII RNA genes in the design of oncolytic adenoviruses
    • Cascallo M, Gros A, Bayo N, et al. Deletion of VAI and VAII RNA genes in the design of oncolytic adenoviruses. Hum Gene Ther 2006;17:929-40.
    • (2006) Hum Gene Ther , vol.17 , pp. 929-940
    • Cascallo, M.1    Gros, A.2    Bayo, N.3
  • 25
    • 0025836816 scopus 로고
    • Retention of adenovirus E19 glycoprotein in the endoplasmic reticulum is essential to its ability to block antigen presentation
    • Cox JH, Bennink JR, Yewdell JW. Retention of adenovirus E19 glycoprotein in the endoplasmic reticulum is essential to its ability to block antigen presentation. J Exp Med 1991;174:1629-37.
    • (1991) J Exp Med , vol.174 , pp. 1629-1637
    • Cox, J.H.1    Bennink, J.R.2    Yewdell, J.W.3
  • 26
    • 0026610807 scopus 로고
    • The 11,600-MW protein encoded by region E3 of adenovirus is expressed early but is greatly amplified at late stages of infection
    • Tollefson AE, Scaria A, Saha SK, Wold WS. The 11,600-MW protein encoded by region E3 of adenovirus is expressed early but is greatly amplified at late stages of infection. J Virol 1992;66:3633-42.
    • (1992) J Virol , vol.66 , pp. 3633-3642
    • Tollefson, A.E.1    Scaria, A.2    Saha, S.K.3    Wold, W.S.4
  • 27
    • 0034431158 scopus 로고    scopus 로고
    • Analysis of free intracellular calcium by flow cytometry: Multiparameter and pharmacologic applications
    • Burchiel SW, Edwards BS, Kuckuck FW, et al. Analysis of free intracellular calcium by flow cytometry: multiparameter and pharmacologic applications. Methods 2000;21:221-30.
    • (2000) Methods , vol.21 , pp. 221-230
    • Burchiel, S.W.1    Edwards, B.S.2    Kuckuck, F.W.3
  • 28
    • 0027538121 scopus 로고
    • Retrieval of transmembrane proteins to the endoplasmic reticulum
    • Jackson MR, Nilsson T, Peterson PA. Retrieval of transmembrane proteins to the endoplasmic reticulum. J Cell Biol 1993;121:317-33.
    • (1993) J Cell Biol , vol.121 , pp. 317-333
    • Jackson, M.R.1    Nilsson, T.2    Peterson, P.A.3
  • 29
    • 0030053047 scopus 로고    scopus 로고
    • Pahl HL, S ester M, Burgert HG, Baeuerle PA. Activation of transcription factor NF-κB by the adenovirus E3/19K protein requires its ER retention. J Cell Biol 1996;132:511-22.
    • Pahl HL, S ester M, Burgert HG, Baeuerle PA. Activation of transcription factor NF-κB by the adenovirus E3/19K protein requires its ER retention. J Cell Biol 1996;132:511-22.
  • 30
    • 0030003101 scopus 로고    scopus 로고
    • The E3-11.6-kDa adenovirus death protein (ADP) is required for efficient cell death: Characterization of cells infected with adp mutants
    • Tollefson AE, Ryerse JS, Scaria A, Hermiston TW, Wold WS. The E3-11.6-kDa adenovirus death protein (ADP) is required for efficient cell death: characterization of cells infected with adp mutants. Virology 1996;220:152-62.
    • (1996) Virology , vol.220 , pp. 152-162
    • Tollefson, A.E.1    Ryerse, J.S.2    Scaria, A.3    Hermiston, T.W.4    Wold, W.S.5
  • 31
    • 0027328712 scopus 로고
    • Deletion mutation analysis of the adenovirus type 2 E3-19K protein: Identification of sequences within the endoplasmic reticulum lumenal domain that are required for class I antigen binding and protection from adenovirus-specific cytotoxic T lymphocytes
    • Hermiston TW, Tripp RA, Sparer T, Gooding LR, Wold WS. Deletion mutation analysis of the adenovirus type 2 E3-19K protein: identification of sequences within the endoplasmic reticulum lumenal domain that are required for class I antigen binding and protection from adenovirus-specific cytotoxic T lymphocytes. J Virol 1993;67:5289-98.
    • (1993) J Virol , vol.67 , pp. 5289-5298
    • Hermiston, T.W.1    Tripp, R.A.2    Sparer, T.3    Gooding, L.R.4    Wold, W.S.5
  • 32
    • 0027991237 scopus 로고
    • Conserved cysteine residues within the E3/19K protein of adenovirus type 2 are essential for binding to major histocompatibility complex antigens
    • Sester M, Burgert HG. Conserved cysteine residues within the E3/19K protein of adenovirus type 2 are essential for binding to major histocompatibility complex antigens. J Virol 1994;68:5423-32.
    • (1994) J Virol , vol.68 , pp. 5423-5432
    • Sester, M.1    Burgert, H.G.2
  • 33
    • 0033136705 scopus 로고    scopus 로고
    • Cutting edge: Adenovirus E19 has two mechanisms for affecting class I MHC expression
    • Bennett EM, Bennink JR, Yewdell JW, Brodsky FM. Cutting edge: adenovirus E19 has two mechanisms for affecting class I MHC expression. J Immunol 1999;162:5049-52.
    • (1999) J Immunol , vol.162 , pp. 5049-5052
    • Bennett, E.M.1    Bennink, J.R.2    Yewdell, J.W.3    Brodsky, F.M.4
  • 34
    • 0021684759 scopus 로고
    • Mutations in the gene encoding the adenovirus early region 1B 19,000-molecular-weight tumor antigen cause the degradation of chromosomal DNA
    • White E, Grodzicker T, Stillman BW. Mutations in the gene encoding the adenovirus early region 1B 19,000-molecular-weight tumor antigen cause the degradation of chromosomal DNA. J Virol 1984;52:410-9.
    • (1984) J Virol , vol.52 , pp. 410-419
    • White, E.1    Grodzicker, T.2    Stillman, B.W.3
  • 35
    • 0038759070 scopus 로고    scopus 로고
    • Tollefson AE, S c aria A, Ying B, Wold WS. Mutations within the ADP (E3-11.6K) protein alter processing and localization of ADP and the kinetics of cell lysis of adenovirus-infected cells. J Virol 2003;77:7764-78.
    • Tollefson AE, S c aria A, Ying B, Wold WS. Mutations within the ADP (E3-11.6K) protein alter processing and localization of ADP and the kinetics of cell lysis of adenovirus-infected cells. J Virol 2003;77:7764-78.
  • 36
    • 0028061226 scopus 로고
    • Fine-mapping of sequences that suppress splicing in the E3 complex transcription unit of adenovirus
    • Scaria A, Wold WS. Fine-mapping of sequences that suppress splicing in the E3 complex transcription unit of adenovirus. Virology 1994;205:406-16.
    • (1994) Virology , vol.205 , pp. 406-416
    • Scaria, A.1    Wold, W.S.2
  • 37
    • 0041333863 scopus 로고    scopus 로고
    • Gonzalez ME, Carrasco L. Viroporins. FEBSLet t 2003;552:28-34.
    • Gonzalez ME, Carrasco L. Viroporins. FEBSLet t 2003;552:28-34.
  • 38
    • 0030928285 scopus 로고    scopus 로고
    • Coxsackievirus protein 2B modifies endoplasmic reticulum membrane and plasma membrane permeability and facilitates virus release
    • van Kuppeveld FJ, Hoenderop JG, Smeets RL, et al. Coxsackievirus protein 2B modifies endoplasmic reticulum membrane and plasma membrane permeability and facilitates virus release. EMBO J 1997;16:3519-32.
    • (1997) EMBO J , vol.16 , pp. 3519-3532
    • van Kuppeveld, F.J.1    Hoenderop, J.G.2    Smeets, R.L.3
  • 39
    • 0021739589 scopus 로고
    • Deletion of the gene encoding the adenovirus 5 early region 1b 21,000-molecular-weight polypeptide leads to degradation of viral and host cell DNA
    • Pilder S, Logan J, Shenk T. Deletion of the gene encoding the adenovirus 5 early region 1b 21,000-molecular-weight polypeptide leads to degradation of viral and host cell DNA. J Virol 1984;52:664-71.
    • (1984) J Virol , vol.52 , pp. 664-671
    • Pilder, S.1    Logan, J.2    Shenk, T.3
  • 40
    • 0022403592 scopus 로고
    • Impaired intracellular transport of class I MHC antigens as a possible means for adenoviruses to evade immune surveillance
    • Andersson M, Paabo S, Nilsson T, Peterson PA. Impaired intracellular transport of class I MHC antigens as a possible means for adenoviruses to evade immune surveillance. Cell 1985;43:215-22.
    • (1985) Cell , vol.43 , pp. 215-222
    • Andersson, M.1    Paabo, S.2    Nilsson, T.3    Peterson, P.A.4
  • 41
    • 0021972750 scopus 로고
    • An adenovirus type 2 glycoprotein blocks cell surface expression of human histocompatibility class I antigens
    • Burgert HG, Kvist S. An adenovirus type 2 glycoprotein blocks cell surface expression of human histocompatibility class I antigens. Cell 1985;41:987-97.
    • (1985) Cell , vol.41 , pp. 987-997
    • Burgert, H.G.1    Kvist, S.2
  • 42
    • 0023514475 scopus 로고
    • A small deletion distant froma splice or polyadenylation site dramatically alters pre-mRNA processing in region E3 of adenovirus
    • Bhat BM, Wold WS. A small deletion distant froma splice or polyadenylation site dramatically alters pre-mRNA processing in region E3 of adenovirus. J Virol 1987;61:3938-45.
    • (1987) J Virol , vol.61 , pp. 3938-3945
    • Bhat, B.M.1    Wold, W.S.2
  • 43
    • 33751292350 scopus 로고    scopus 로고
    • Cytobiological consequences of calcium-signaling alterations induced by human viral proteins
    • Chami M, Oules B, Paterlini-Brechot P. Cytobiological consequences of calcium-signaling alterations induced by human viral proteins. Biochim Biophys Acta 2006;1763:1344-62.
    • (2006) Biochim Biophys Acta , vol.1763 , pp. 1344-1362
    • Chami, M.1    Oules, B.2    Paterlini-Brechot, P.3
  • 44
    • 0036203022 scopus 로고    scopus 로고
    • Multimerization reactions of coxsackievirus proteins 2B, 2C and 2BC: A mammalian two-hybrid analysis
    • de Jong AS, Schrama IW, Willems PH, et al. Multimerization reactions of coxsackievirus proteins 2B, 2C and 2BC: a mammalian two-hybrid analysis. J Gen Virol 2002;83:783-93.
    • (2002) J Gen Virol , vol.83 , pp. 783-793
    • de Jong, A.S.1    Schrama, I.W.2    Willems, P.H.3
  • 45
    • 0042072321 scopus 로고    scopus 로고
    • The human immunodeficiency virus type 1 Vpu protein enhances membrane permeability
    • Gonzalez ME, Carrasco L. The human immunodeficiency virus type 1 Vpu protein enhances membrane permeability. Biochemistry 1998;37:13710-9.
    • (1998) Biochemistry , vol.37 , pp. 13710-13719
    • Gonzalez, M.E.1    Carrasco, L.2
  • 46
    • 0028221512 scopus 로고
    • Influenza virus M2 protein modifies membrane permeability in E. coli cells
    • Guinea R, Carrasco L. Influenza virus M2 protein modifies membrane permeability in E. coli cells. FEBS Lett 1994;343:242-6.
    • (1994) FEBS Lett , vol.343 , pp. 242-246
    • Guinea, R.1    Carrasco, L.2
  • 47
    • 42449144285 scopus 로고    scopus 로고
    • Adenovirus E3/19K promotes evasion of NK cell recognition by intracellular sequestration of the NKG2D ligands major histocompatibility complex class I chain-related proteins A and B
    • McSharry BP, Burgert HG, Owen DP, et al. Adenovirus E3/19K promotes evasion of NK cell recognition by intracellular sequestration of the NKG2D ligands major histocompatibility complex class I chain-related proteins A and B. J Virol 2008;82:4585-94.
    • (2008) J Virol , vol.82 , pp. 4585-4594
    • McSharry, B.P.1    Burgert, H.G.2    Owen, D.P.3
  • 48
    • 0027208574 scopus 로고
    • Proteins with transcription regulatory properties encoded by human adenoviruses
    • Akusjarvi G. Proteins with transcription regulatory properties encoded by human adenoviruses. Trends Microbiol 1993;1:163-70.
    • (1993) Trends Microbiol , vol.1 , pp. 163-170
    • Akusjarvi, G.1
  • 49
    • 34548558821 scopus 로고    scopus 로고
    • ICOVIR-5 shows E2F1 addiction and potent antiglioma effect in vivo
    • Alonso MM, Cascallo M, Gomez-Manzano C, et al. ICOVIR-5 shows E2F1 addiction and potent antiglioma effect in vivo. Cancer Res 2007;67:8255-63.
    • (2007) Cancer Res , vol.67 , pp. 8255-8263
    • Alonso, M.M.1    Cascallo, M.2    Gomez-Manzano, C.3
  • 51
    • 0033838922 scopus 로고    scopus 로고
    • Proliferative activity of intratumoral fibroblasts is closely correlated with lymph node and distant organ metastases of invasive ductal carcinoma of the breast
    • Hasebe T, Sasaki S, Imoto S, Ochiai A. Proliferative activity of intratumoral fibroblasts is closely correlated with lymph node and distant organ metastases of invasive ductal carcinoma of the breast. Am J Pathol 2000;156:1701-10.
    • (2000) Am J Pathol , vol.156 , pp. 1701-1710
    • Hasebe, T.1    Sasaki, S.2    Imoto, S.3    Ochiai, A.4


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