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Volumn 67, Issue 17, 2007, Pages 8255-8263

ICOVIR-5 shows E2F1 addiction and potent antiglioma effect in vivo

Author keywords

[No Author keywords available]

Indexed keywords

ONCOLYTIC ADENOVIRUS; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F1;

EID: 34548558821     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-4675     Document Type: Article
Times cited : (59)

References (37)
  • 1
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp R , Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005;352:987-96.
    • (2005) N Engl J Med , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    van den Bent, M.J.3
  • 3
    • 0030070484 scopus 로고    scopus 로고
    • CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated
    • Ueki K, Ono Y, Henson JW, et al. CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated. Cancer Res 1996;56:150-3.
    • (1996) Cancer Res , vol.56 , pp. 150-153
    • Ueki, K.1    Ono, Y.2    Henson, J.W.3
  • 4
    • 0037079003 scopus 로고    scopus 로고
    • Rules for making human tumor cells
    • Hahn WC, Weinberg RA. Rules for making human tumor cells. N Engl J Med 2002;347:1593-603.
    • (2002) N Engl J Med , vol.347 , pp. 1593-1603
    • Hahn, W.C.1    Weinberg, R.A.2
  • 5
    • 27944502157 scopus 로고    scopus 로고
    • Viruses - seeking and destroying the tumor program
    • O'Shea CC. Viruses - seeking and destroying the tumor program. Oncogene 2005;24:7640-55.
    • (2005) Oncogene , vol.24 , pp. 7640-7655
    • O'Shea, C.C.1
  • 6
    • 0022964245 scopus 로고
    • Functions of adenovirus E1A
    • Berk AJ. Functions of adenovirus E1A. Cancer Surv 1986;5:367-87.
    • (1986) Cancer Surv , vol.5 , pp. 367-387
    • Berk, A.J.1
  • 7
    • 0024968181 scopus 로고
    • Cellular targets for transformation by the adenovirus E1A proteins
    • Whyte P, Williamson NM, Harlow E. Cellular targets for transformation by the adenovirus E1A proteins. Cell 1989;56:67-75.
    • (1989) Cell , vol.56 , pp. 67-75
    • Whyte, P.1    Williamson, N.M.2    Harlow, E.3
  • 8
    • 0034610723 scopus 로고    scopus 로고
    • A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo
    • Fueyo J, Gomez-Manzano C, Alemany R, et al. A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo. Oncogene 2000;19:2-12.
    • (2000) Oncogene , vol.19 , pp. 2-12
    • Fueyo, J.1    Gomez-Manzano, C.2    Alemany, R.3
  • 9
    • 0033782862 scopus 로고    scopus 로고
    • An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy
    • Heise C, Hermiston T, Johnson L, et al. An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy. Nat Med 2000;6:1134-9.
    • (2000) Nat Med , vol.6 , pp. 1134-1139
    • Heise, C.1    Hermiston, T.2    Johnson, L.3
  • 10
    • 0034671907 scopus 로고    scopus 로고
    • Advanced generation adenoviral vectors possess augmented gene transfer efficiency based upon coxsackie adenovirus receptor-independent cellular entry capacity
    • Krasnykh V, Dmitriev I, Navarro JG, et al. Advanced generation adenoviral vectors possess augmented gene transfer efficiency based upon coxsackie adenovirus receptor-independent cellular entry capacity. Cancer Res 2000;60:6784-7.
    • (2000) Cancer Res , vol.60 , pp. 6784-6787
    • Krasnykh, V.1    Dmitriev, I.2    Navarro, J.G.3
  • 11
    • 0035138689 scopus 로고    scopus 로고
    • A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency
    • Suzuki K, Fueyo J, Krasnykh V, et al. A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency. Clin Cancer Res 2001;7:120-6.
    • (2001) Clin Cancer Res , vol.7 , pp. 120-126
    • Suzuki, K.1    Fueyo, J.2    Krasnykh, V.3
  • 12
    • 0038288854 scopus 로고    scopus 로고
    • Preclinical characterization of the antiglioma activity of a tropism-enhanced adenovirus targeted to the retinoblastoma pathway
    • Fueyo J, Alemany R, Gomez-Manzano C, et al. Preclinical characterization of the antiglioma activity of a tropism-enhanced adenovirus targeted to the retinoblastoma pathway. J Natl Cancer Inst 2003;95:652-60.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 652-660
    • Fueyo, J.1    Alemany, R.2    Gomez-Manzano, C.3
  • 13
    • 0035956213 scopus 로고    scopus 로고
    • Regulation of the cell cycle and apoptosis by the oncogenes of adenovirus
    • White E. Regulation of the cell cycle and apoptosis by the oncogenes of adenovirus. Oncogene 2001;20:7836-46.
    • (2001) Oncogene , vol.20 , pp. 7836-7846
    • White, E.1
  • 14
    • 27944464545 scopus 로고    scopus 로고
    • Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus
    • Berk AJ. Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus. Oncogene 2005;24:7673-85.
    • (2005) Oncogene , vol.24 , pp. 7673-7685
    • Berk, A.J.1
  • 15
    • 19044386714 scopus 로고    scopus 로고
    • Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents
    • Johnson L, Shen A, Boyle L, et al. Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents. Cancer Cell 2002;1:325-37.
    • (2002) Cancer Cell , vol.1 , pp. 325-337
    • Johnson, L.1    Shen, A.2    Boyle, L.3
  • 16
    • 0037379880 scopus 로고    scopus 로고
    • An oncolytic adenovirus selective for retinoblastoma tumor suppressor protein pathway-defective tumors: Dependence on E1A, the E2F-1 promoter, and viral replication for selectivity and efficacy
    • Jakubczak JL, Ryan P, Gorziglia M, et al. An oncolytic adenovirus selective for retinoblastoma tumor suppressor protein pathway-defective tumors: dependence on E1A, the E2F-1 promoter, and viral replication for selectivity and efficacy. Cancer Res 2003;63:1490-9.
    • (2003) Cancer Res , vol.63 , pp. 1490-1499
    • Jakubczak, J.L.1    Ryan, P.2    Gorziglia, M.3
  • 17
    • 4043135736 scopus 로고    scopus 로고
    • Antitumor efficacy and tumor-selective replication with a single intravenous injection of OAS403, an oncolytic adenovirus dependent on two prevalent alterations in human cancer
    • Ryan PC, Jakubczak JL, Stewart DA, et al. Antitumor efficacy and tumor-selective replication with a single intravenous injection of OAS403, an oncolytic adenovirus dependent on two prevalent alterations in human cancer. Cancer Gene Ther 2004;11:555-69.
    • (2004) Cancer Gene Ther , vol.11 , pp. 555-569
    • Ryan, P.C.1    Jakubczak, J.L.2    Stewart, D.A.3
  • 18
    • 0017870263 scopus 로고
    • Isolation of deletion and substitution mutants of adenovirus type 5
    • Jones N, Shenk T. Isolation of deletion and substitution mutants of adenovirus type 5. Cell 1978;13:181-8.
    • (1978) Cell , vol.13 , pp. 181-188
    • Jones, N.1    Shenk, T.2
  • 19
    • 0242652179 scopus 로고    scopus 로고
    • Cellular uptake and nuclear delivery of recombinant adenovirus penton base
    • Hong SS, Gay B, Karayan L, Dabauvalle MC, Boulanger P. Cellular uptake and nuclear delivery of recombinant adenovirus penton base. Virology 1999;262:163-77.
    • (1999) Virology , vol.262 , pp. 163-177
    • Hong, S.S.1    Gay, B.2    Karayan, L.3    Dabauvalle, M.C.4    Boulanger, P.5
  • 20
    • 33747600882 scopus 로고    scopus 로고
    • Control of E1A under an E2F-1 promoter insulated with the myotonic dystrophy locus insulator reduces the toxicity of oncolytic adenovirus Ad-Δ24RGD
    • Majem M, Cascallo M, Bayo-Puxan N, et al. Control of E1A under an E2F-1 promoter insulated with the myotonic dystrophy locus insulator reduces the toxicity of oncolytic adenovirus Ad-Δ24RGD. Cancer Gene Ther 2006;13:696-705.
    • (2006) Cancer Gene Ther , vol.13 , pp. 696-705
    • Majem, M.1    Cascallo, M.2    Bayo-Puxan, N.3
  • 21
    • 0028364529 scopus 로고
    • Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression
    • Johnson DG, Ohtani K, Nevins JR. Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes Dev 1994;8:1514-25.
    • (1994) Genes Dev , vol.8 , pp. 1514-1525
    • Johnson, D.G.1    Ohtani, K.2    Nevins, J.R.3
  • 22
    • 0030838479 scopus 로고    scopus 로고
    • Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis
    • Gomez-Manzano C, Fueyo J, Kyritsis AP, et al. Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis. J Natl Cancer Inst 1997;89:1036-44.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1036-1044
    • Gomez-Manzano, C.1    Fueyo, J.2    Kyritsis, A.P.3
  • 23
    • 0031798246 scopus 로고    scopus 로고
    • The functional role of tumor suppressor genes in gliomas: Clues for future therapeutic strategies
    • Fueyo J, Gomez-Manzano C, Yung WK, Kyritsis AP. The functional role of tumor suppressor genes in gliomas: clues for future therapeutic strategies. Neurology 1998;51:1250-5.
    • (1998) Neurology , vol.51 , pp. 1250-1255
    • Fueyo, J.1    Gomez-Manzano, C.2    Yung, W.K.3    Kyritsis, A.P.4
  • 24
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCRand the 2(-ΔΔC(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCRand the 2(-ΔΔC(T)) method. Methods 2001;25:402-8.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 25
    • 0033960389 scopus 로고    scopus 로고
    • An implantable guide-screw system for brain tumor studies in small animals
    • Lal S, Lacroix M, Tofilon P, et al. An implantable guide-screw system for brain tumor studies in small animals. J Neurosurg 2000;92:326-33.
    • (2000) J Neurosurg , vol.92 , pp. 326-333
    • Lal, S.1    Lacroix, M.2    Tofilon, P.3
  • 26
    • 0034804174 scopus 로고    scopus 로고
    • Xylene-free method for histological preparation: A multicentre evaluation
    • Falkeholm L, Grant CA, Magnusson A, Mèoller E. Xylene-free method for histological preparation: a multicentre evaluation. Lab Invest 2001;81:1213-21.
    • (2001) Lab Invest , vol.81 , pp. 1213-1221
    • Falkeholm, L.1    Grant, C.A.2    Magnusson, A.3    Mèoller, E.4
  • 27
    • 0027491775 scopus 로고
    • Expression of transcription factor E2F1 induces quiescent cells to enter S phase
    • Johnson DG, Schwarz JK, Cress WD, Nevins JR. Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature 1993;365:349-52.
    • (1993) Nature , vol.365 , pp. 349-352
    • Johnson, D.G.1    Schwarz, J.K.2    Cress, W.D.3    Nevins, J.R.4
  • 28
    • 0034660892 scopus 로고    scopus 로고
    • The Pezcoller lecture: Cancer cell cycles revisited
    • Sherr CJ. The Pezcoller lecture: cancer cell cycles revisited. Cancer Res 2000;60:3689-95.
    • (2000) Cancer Res , vol.60 , pp. 3689-3695
    • Sherr, C.J.1
  • 29
    • 0001510491 scopus 로고    scopus 로고
    • The RB and p53 pathways in cancer
    • Sherr CJ, McCormick F. The RB and p53 pathways in cancer. Cancer Cell 2002;2:103-12.
    • (2002) Cancer Cell , vol.2 , pp. 103-112
    • Sherr, C.J.1    McCormick, F.2
  • 31
    • 0029612231 scopus 로고
    • A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites
    • Sellers WR, Rodgers JW, Kaelin WG, Jr. A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites. Proc Natl Acad Sci U S A 1995;92:11544-8.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 11544-11548
    • Sellers, W.R.1    Rodgers, J.W.2    Kaelin Jr, W.G.3
  • 32
    • 0030860227 scopus 로고    scopus 로고
    • Tumor-selective transgene expression in vivo mediated by an E2F-responsive adenoviral vector
    • Parr MJ, Manome Y, Tanaka T, et al. Tumor-selective transgene expression in vivo mediated by an E2F-responsive adenoviral vector. Nat Med 1997;3:1145-9.
    • (1997) Nat Med , vol.3 , pp. 1145-1149
    • Parr, M.J.1    Manome, Y.2    Tanaka, T.3
  • 33
    • 27944476391 scopus 로고    scopus 로고
    • Expression of transcription factor E2F1 and telomerase in glioblastomas: Mechanistic linkage and prognostic significance
    • Alonso MM, Fueyo J, Shay JW, et al. Expression of transcription factor E2F1 and telomerase in glioblastomas: mechanistic linkage and prognostic significance. J Natl Cancer Inst 2005;97:1589-600.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1589-1600
    • Alonso, M.M.1    Fueyo, J.2    Shay, J.W.3
  • 34
    • 0031775399 scopus 로고    scopus 로고
    • An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism
    • Dmitriev I, Krasnykh V, Miller CR, et al. An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism. J Virol 1998;72:9706-13.
    • (1998) J Virol , vol.72 , pp. 9706-9713
    • Dmitriev, I.1    Krasnykh, V.2    Miller, C.R.3
  • 35
    • 0027753101 scopus 로고
    • Characterization of integrin receptors in normal and neoplastic human brain
    • Paulus W, Baur I, Schuppan D, Roggendorf W. Characterization of integrin receptors in normal and neoplastic human brain. Am J Pathol 1993;143:154-63.
    • (1993) Am J Pathol , vol.143 , pp. 154-163
    • Paulus, W.1    Baur, I.2    Schuppan, D.3    Roggendorf, W.4
  • 36
    • 27544459331 scopus 로고    scopus 로고
    • In situ analysis of integrin and growth factor receptor signaling pathways in human glioblastomas suggests overlapping relationships with focal adhesion kinase activation
    • Riemenschneider MJ, Mueller W, Betensky RA, Mohapatra G, Louis DN. In situ analysis of integrin and growth factor receptor signaling pathways in human glioblastomas suggests overlapping relationships with focal adhesion kinase activation. Am J Pathol 2005;167:1379-87.
    • (2005) Am J Pathol , vol.167 , pp. 1379-1387
    • Riemenschneider, M.J.1    Mueller, W.2    Betensky, R.A.3    Mohapatra, G.4    Louis, D.N.5
  • 37
    • 27944472282 scopus 로고    scopus 로고
    • Meeting product development challenges in manufacturing clinical grade oncolytic adenoviruses
    • Working PK, Lin A, Borellini F. Meeting product development challenges in manufacturing clinical grade oncolytic adenoviruses. Oncogene 2005;24:7792-801.
    • (2005) Oncogene , vol.24 , pp. 7792-7801
    • Working, P.K.1    Lin, A.2    Borellini, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.