메뉴 건너뛰기




Volumn 63, Issue 6, 2003, Pages 1317-1324

Validation and analysis of a mathematical model of a replication-competent oncolytic virus for cancer treatment: Implications for virus design and delivery

Author keywords

[No Author keywords available]

Indexed keywords

ONCOLYTIC VIRUS;

EID: 0037444281     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (180)

References (37)
  • 1
    • 0035523825 scopus 로고    scopus 로고
    • Cancer gene therapy: Fringe or cutting edge?
    • McCormick, F. Cancer gene therapy: fringe or cutting edge? Nat. Rev. Cancer, 1: 130-141, 2001.
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 130-141
    • McCormick, F.1
  • 2
    • 0034927057 scopus 로고    scopus 로고
    • Replication-selective virotherapy for cancer: Biological principles, risk management and future directions
    • Kirn, D., Martuza, R. L., and Zwiebel, J. Replication-selective virotherapy for cancer: biological principles, risk management and future directions. Nat. Med., 7: 781-787, 2001.
    • (2001) Nat. Med. , vol.7 , pp. 781-787
    • Kirn, D.1    Martuza, R.L.2    Zwiebel, J.3
  • 4
    • 0030917202 scopus 로고    scopus 로고
    • ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents
    • Heise, C., Sampson-Johannes, A., Williams, A., McCormick, F., Von Hoff, D. D., and Kirn, D. H. ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents. Nat. Med., 3: 639-645, 1997.
    • (1997) Nat. Med. , vol.3 , pp. 639-645
    • Heise, C.1    Sampson-Johannes, A.2    Williams, A.3    McCormick, F.4    Von Hoff, D.D.5    Kirn, D.H.6
  • 5
    • 0035863499 scopus 로고    scopus 로고
    • Antitumor synergy of CN787, a prostate cancer-specific adenovirus, and paclitaxel and docetaxel
    • Yu, D., Chen, Y., Dilley, J., Li, Y., Embry, M., Zhang, H., Amin, P., Oh, J., and Henderson, D. Antitumor synergy of CN787, a prostate cancer-specific adenovirus, and paclitaxel and docetaxel. Cancer Res., 61: 517-525, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 517-525
    • Yu, D.1    Chen, Y.2    Dilley, J.3    Li, Y.4    Embry, M.5    Zhang, H.6    Amin, P.7    Oh, J.8    Henderson, D.9
  • 8
    • 0029023868 scopus 로고
    • Attenuated multimutated herpes simplex virus-1 for the treatment of malignant gliomas
    • Mineta, T., Rabkin, S., Yazaki, T., Hunter, W., and Martuza, R. Attenuated multimutated herpes simplex virus-1 for the treatment of malignant gliomas. Nat. Med., 1: 938-943, 1995.
    • (1995) Nat. Med. , vol.1 , pp. 938-943
    • Mineta, T.1    Rabkin, S.2    Yazaki, T.3    Hunter, W.4    Martuza, R.5
  • 9
    • 0030790684 scopus 로고    scopus 로고
    • Prostate attenuated replication competent adenovirus (ARCA) CN706: A selective cytotoxic for prostate-specific antigen-positive prostate cancer cells
    • Rodriguez, R., Schuur, E. R., Lim, H. Y., Henderson, G. A., Simons, J. W., and Henderson, D. R. Prostate attenuated replication competent adenovirus (ARCA) CN706: a selective cytotoxic for prostate-specific antigen-positive prostate cancer cells. Cancer Res., 57: 2559-2563, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 2559-2563
    • Rodriguez, R.1    Schuur, E.R.2    Lim, H.Y.3    Henderson, G.A.4    Simons, J.W.5    Henderson, D.R.6
  • 10
  • 11
    • 0033693231 scopus 로고    scopus 로고
    • Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: A Phase II trial
    • Nemunaitis, J., Ganly, I., Khuri, F., Arseneau, J., Kuhn, J., McCarty, T., Landers, S., Maples, P., Romel, L., Randley, B., Reid, T., Kaye, S., and Kirn, D. Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a Phase II trial. Cancer Res., 60: 6359-6366, 2000.
    • (2000) Cancer Res. , vol.60 , pp. 6359-6366
    • Nemunaitis, J.1    Ganly, I.2    Khuri, F.3    Arseneau, J.4    Kuhn, J.5    McCarty, T.6    Landers, S.7    Maples, P.8    Romel, L.9    Randley, B.10    Reid, T.11    Kaye, S.12    Kirn, D.13
  • 12
    • 0035134629 scopus 로고    scopus 로고
    • Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: What have we learned?
    • Kirn, D. Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: what have we learned? Gene Ther., 8: 89-98, 2001.
    • (2001) Gene Ther. , vol.8 , pp. 89-98
    • Kirn, D.1
  • 15
    • 0023805167 scopus 로고
    • Mathematical model of simultaneous diffusion and binding of antitumor antibodies in multicellular human tumor spheroids
    • McFadden, R., and Kwok, C. S. Mathematical model of simultaneous diffusion and binding of antitumor antibodies in multicellular human tumor spheroids. Cancer Res., 48: 4032-4037, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 4032-4037
    • McFadden, R.1    Kwok, C.S.2
  • 16
    • 0026425576 scopus 로고
    • An analysis of monoclonal antibody distribution in microscopic tumor nodules: Consequences of a "binding site barrier"
    • van Osdol, W., Fujimori, K., and Weinstein, J. N. An analysis of monoclonal antibody distribution in microscopic tumor nodules: consequences of a "binding site barrier." Cancer Res., 51: 4776-4784, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 4776-4784
    • Van Osdol, W.1    Fujimori, K.2    Weinstein, J.N.3
  • 17
    • 0024584819 scopus 로고
    • Transport of fluid and macromolecules in tumors. I. Role of interstitial pressure and convection
    • Baxter, L. T., and Jain, R. K. Transport of fluid and macromolecules in tumors. I. Role of interstitial pressure and convection. Microvasc. Res., 37: 77-104, 1989.
    • (1989) Microvasc. Res. , vol.37 , pp. 77-104
    • Baxter, L.T.1    Jain, R.K.2
  • 18
    • 0025065107 scopus 로고
    • Transport of fluid and macromolecules in tumors. II. Role of heterogeneous perfusion and lymphatics
    • Baxter, L. T., and Jain, R. K. Transport of fluid and macromolecules in tumors. II. Role of heterogeneous perfusion and lymphatics. Microvasc. Res., 40: 246-263, 1990.
    • (1990) Microvasc. Res. , vol.40 , pp. 246-263
    • Baxter, L.T.1    Jain, R.K.2
  • 19
    • 0025869933 scopus 로고
    • Transport of fluid and macromolecules in tumors. III. Role of binding and metabolism
    • Baxter, L. T., and Jain. R. K. Transport of fluid and macromolecules in tumors. III. Role of binding and metabolism. Microvasc. Res., 41: 5-23, 1991.
    • (1991) Microvasc. Res. , vol.41 , pp. 5-23
    • Baxter, L.T.1    Jain, R.K.2
  • 20
    • 0016277217 scopus 로고
    • Diffusion and convection in normal and neoplastic tissues
    • Swabb, E. A., Wei, J., and Gullino, P. M. Diffusion and convection in normal and neoplastic tissues. Cancer Res., 34: 2814-2822, 1974.
    • (1974) Cancer Res. , vol.34 , pp. 2814-2822
    • Swabb, E.A.1    Wei, J.2    Gullino, P.M.3
  • 21
    • 0028470454 scopus 로고
    • Barriers to drug delivery in solid tumors
    • Jain, R. Barriers to drug delivery in solid tumors. Sci. Am., 271: 58-65, 1994.
    • (1994) Sci. Am. , vol.271 , pp. 58-65
    • Jain, R.1
  • 23
    • 0034905801 scopus 로고    scopus 로고
    • Modeling and analysis of a virus that replicates selectively in tumor cells
    • Wu, J. T., Byrne, H. M., Kirn, D. H., and Wein, L. M. Modeling and analysis of a virus that replicates selectively in tumor cells. Bull. Math. Biol., 63: 731-768, 2001.
    • (2001) Bull. Math. Biol. , vol.63 , pp. 731-768
    • Wu, J.T.1    Byrne, H.M.2    Kirn, D.H.3    Wein, L.M.4
  • 24
    • 0012553176 scopus 로고    scopus 로고
    • Analysis of a three-way race between tumor growth, a replication-competent virus and an immune response
    • in press
    • Wu, J. T., Kirn, D. H., and Wein, L. M. Analysis of a three-way race between tumor growth, a replication-competent virus and an immune response. Bulletin Math Biol., in press, 2003.
    • (2003) Bulletin Math Biol.
    • Wu, J.T.1    Kirn, D.H.2    Wein, L.M.3
  • 25
    • 0035177690 scopus 로고    scopus 로고
    • Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: A Phase I trial
    • Reid, T., Galanis, E., Abbruzzese, J., Sze, D., Andrews, J., Romel, L., Hatfield, M., Rubin, J., and Kirn, D. Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a Phase I trial. Gene Ther., 8: 1618-26, 2001.
    • (2001) Gene Ther. , vol.8 , pp. 1618-1626
    • Reid, T.1    Galanis, E.2    Abbruzzese, J.3    Sze, D.4    Andrews, J.5    Romel, L.6    Hatfield, M.7    Rubin, J.8    Kirn, D.9
  • 26
    • 0033218746 scopus 로고    scopus 로고
    • Efficacy of a replication-competent adenovirus (ONYX-015) is associated with intratumoral distribution
    • Heise, C., Williams, A., Olesch, J., and Kirn, D. H. Efficacy of a replication-competent adenovirus (ONYX-015) is associated with intratumoral distribution. Cancer Gene Ther., 6: 499-504, 1999.
    • (1999) Cancer Gene Ther. , vol.6 , pp. 499-504
    • Heise, C.1    Williams, A.2    Olesch, J.3    Kirn, D.H.4
  • 27
    • 0032471162 scopus 로고    scopus 로고
    • Cancer gene therapy using a replication-competent herpes simplex virus type I vector
    • Yoon, S. S., Carroll, N. M., Chiocca, E. A., and Tanabe, K. K. Cancer gene therapy using a replication-competent herpes simplex virus type I vector. Ann. Surg., 228: 366-374, 1998.
    • (1998) Ann. Surg. , vol.228 , pp. 366-374
    • Yoon, S.S.1    Carroll, N.M.2    Chiocca, E.A.3    Tanabe, K.K.4
  • 28
    • 0033152894 scopus 로고    scopus 로고
    • Intravenous administration of ONYX-015, a selectively replicating adenovirus, induces antitumoral efficacy
    • Heise, C. C., Williams, A. M., Xue, S., Propst, M. and Kirn, D. H. Intravenous administration of ONYX-015, a selectively replicating adenovirus, induces antitumoral efficacy. Cancer Res., 59: 2623-2628, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 2623-2628
    • Heise, C.C.1    Williams, A.M.2    Xue, S.3    Propst, M.4    Kirn, D.H.5
  • 29
    • 0028842671 scopus 로고
    • Relationships between tumor size and curability for uniformly targeted therapy with β-emitting radionuclides
    • O'Donoghue, J. A., Bardies, M., and Wheldon, T. E. Relationships between tumor size and curability for uniformly targeted therapy with β-emitting radionuclides. J. Nucl. Med., 36: 1902-1909, 1995.
    • (1995) J. Nucl. Med. , vol.36 , pp. 1902-1909
    • O'Donoghue, J.A.1    Bardies, M.2    Wheldon, T.E.3
  • 30
    • 0025719447 scopus 로고
    • The phantom of tumor treatment - Continually rapid proliferation unmasked
    • Fowler, J. F. The phantom of tumor treatment - continually rapid proliferation unmasked. Radiother. Oncol., 22: 156-158, 1991.
    • (1991) Radiother. Oncol. , vol.22 , pp. 156-158
    • Fowler, J.F.1
  • 31
    • 0031039632 scopus 로고    scopus 로고
    • Interstitial fluid pressure in intracranial tumours in patients and in rodents
    • Boucher, Y., Salehi, H., Witwer, B., Harsh, IV, G. R., and Jain, R. K. Interstitial fluid pressure in intracranial tumours in patients and in rodents. Br. J. Cancer (Phil.), 75: 829-836, 1997.
    • (1997) Br. J. Cancer (Phil.) , vol.75 , pp. 829-836
    • Boucher, Y.1    Salehi, H.2    Witwer, B.3    Harsh G.R. IV4    Jain, R.K.5
  • 33
    • 0034086730 scopus 로고    scopus 로고
    • Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein
    • Doronin, K., Toth, K., Kuppuswamy, M., Ward, P., Tollefson, A., and Wold, W. Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein. J. Virol., 74: 6147-6155, 2000.
    • (2000) J. Virol. , vol.74 , pp. 6147-6155
    • Doronin, K.1    Toth, K.2    Kuppuswamy, M.3    Ward, P.4    Tollefson, A.5    Wold, W.6
  • 34
    • 0034893340 scopus 로고    scopus 로고
    • Gene delivery from the E3 region of replicating human adenovirus: Evaluation of the ADP region
    • Hawkins, L. K., and Hermiston, T. Gene delivery from the E3 region of replicating human adenovirus: evaluation of the ADP region. Gene Ther., 15: 1142-1148, 2001.
    • (2001) Gene Ther. , vol.15 , pp. 1142-1148
    • Hawkins, L.K.1    Hermiston, T.2
  • 36
    • 0035870287 scopus 로고    scopus 로고
    • Viruses as antitumor weapons: Defining conditions for tumor remission
    • Wodarz, D. Viruses as antitumor weapons: defining conditions for tumor remission. Cancer Res., 61: 3501-3507, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 3501-3507
    • Wodarz, D.1
  • 37


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.